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Otago Medical School staff profiles

Dr Stephen Sowerby

PositionHonorary Senior Research Fellow
DepartmentDepartment of Biochemistry
QualificationsBSc (Hons) PhD
Research summaryBioengineering

Research

My research interest is in the area of Bioengineering: the use and the development of devices and technologies and the management and commercialisation of associated intellectual property for the physical and chemical investigation of biological systems.

Publications

Ayana, M., Vlaminck, J., Cools, P., Ame, S., Albonico, M., Dana, D., … Sowerby, S., … Levecke, B. (2018). Modification and optimization of the FECPAKG2 protocol for the detection and quantification of soil-transmitted helminth eggs in human stool. PLoS Neglected Tropical Diseases, 12(10), e0006655. doi: 10.1371/journal.pntd.0006655

Sowerby, S. J., Crump, J. A., Johnstone, M. C., Krause, K. L., & Hill, P. C. (2016). Smartphone microscopy of parasite eggs accumulated into a single field of view. American Journal of Tropical Medicine & Hygiene, 94(1), 227-230. doi: 10.4269/ajtmh.15-0427

Hoekendijk, D. J. L., Hill, P. C., & Sowerby, S. J. (2016). Rationale for quality assurance in fecal egg monitoring of soil-transmitted helminthiasis [Perspective]. American Journal of Tropical Medicine & Hygiene, 95(3), 502-504. doi: 10.4269/ajtmh.15-0463

Cooke, I. R., Laing, C. J., White, L. V., Wakes, S. J., & Sowerby, S. J. (2015). Analysis of menisci formed on cones for single field of view parasite egg microscopy. Journal of Microscopy, 257(2), 133-141. doi: 10.1111/jmi.12192

White, L. V., Cooke, I. R., Wakes, S. J., & Sowerby, S. J. (2013). Quantitative particle microscopy in self-metered fluids. Journal of Microscopy, 250(3), 159-165. doi: 10.1111/jmi.12031

Journal - Research Article

Ayana, M., Vlaminck, J., Cools, P., Ame, S., Albonico, M., Dana, D., … Sowerby, S., … Levecke, B. (2018). Modification and optimization of the FECPAKG2 protocol for the detection and quantification of soil-transmitted helminth eggs in human stool. PLoS Neglected Tropical Diseases, 12(10), e0006655. doi: 10.1371/journal.pntd.0006655

Sowerby, S. J., Crump, J. A., Johnstone, M. C., Krause, K. L., & Hill, P. C. (2016). Smartphone microscopy of parasite eggs accumulated into a single field of view. American Journal of Tropical Medicine & Hygiene, 94(1), 227-230. doi: 10.4269/ajtmh.15-0427

Cooke, I. R., Laing, C. J., White, L. V., Wakes, S. J., & Sowerby, S. J. (2015). Analysis of menisci formed on cones for single field of view parasite egg microscopy. Journal of Microscopy, 257(2), 133-141. doi: 10.1111/jmi.12192

White, L. V., Cooke, I. R., Wakes, S. J., & Sowerby, S. J. (2013). Quantitative particle microscopy in self-metered fluids. Journal of Microscopy, 250(3), 159-165. doi: 10.1111/jmi.12031

Sowerby, S. J., Mirams, G. J., Hill, P. C., & Paulin, M. G. (2011). An axisymmetric meniscus converges particles for microscopy. Journal of Microscopy, 244(3), 230-234. doi: 10.1111/j.1365-2818.2011.03527.x

Sowerby, S. J., & Petersen, G. B. (2009). A proposition for single molecule DNA sequencing through a nanopore entropie trap. International Journal of Nanotechnology, 6(3-4), 398-407. doi: 10.1504/IJNT.2009.022928

Sowerby, S. J., Broom, M. F., & Petersen, G. B. (2007). Dynamically resizable nanometre-scale apertures for molecular sensing. Sensors & Actuators B, 123(1), 325-330. doi: 10.1016/j.snb.2006.08.031

Sowerby, S. J., & Petersen, G. B. (2002). Life Before RNA. Astrobiology, 2(3), 231-239.

Sowerby, S. J., Holm, N. G., & Petersen, G. B. (2001). Origins of life: A route to nanotechnology. Biosystems, 61, 69-78.

Sowerby, S. J., Stockwell, P. A., Heckl, W. M., & Petersen, G. B. (2000). Self-programmable, self-assembling, two dimensional genetic matter. Origins of Life & Evolution of the Biosphere, 30, 81-99.

Benjes, S. M., Millow, L. J., Jeffs, A. R., Sowerby, S. J., Reeve, A. E., & Morris, C. M. (1999). 3' BCR recombines with IGL locus in BCR-ABL-positive Philadelphia-negative chronic myeloid leukaemia. Genes Chromosomes & Cancer, 26(4), 366-371.

Frevel, M. A. E., Sowerby, S. J., Petersen, G. B., & Reeve, A. E. (1999). Methylation sequencing analysis refines the region of H19 epimutation in Wilms Tumor. Journal of Biological Chemistry, 274(41), 29331-29340.

Sowerby, S. J., Edelwirth, M., & Heckl, W. M. (1998). Self-assembly at the prebiotic solid-liquid interface: Structures of self-assembled monolayers of adenine and guanine bases formed on inorganic surfaces. Journal of Physical Chemistry B, 102(30), 5914-5922.

Sowerby, S. J., & Heckl, W. M. (1998). The role of self-assembled monolayers of the purine and pyrimidine bases in the emergence of life. Origins of Life & Evolution of the Biosphere, 28, 283-310.

Jeffs, A. R., Benjes, S. M., Smith, T. L., Sowerby, S. J., & Morris, C. M. (1998). The BCR gene recombines preferentially with Alu elements in complex BCR-ABL translocations of chronic myeloid leukaemia. Human Molecular Genetics, 7, 767-776.

Sowerby, S. J., Edelwirth, M., Reiter, M., & Heckl, W. M. (1998). Scanning tunneling microscopy image contrast as a function of scan angle in hydrogen-bonded self-assembled monolayers. Langmuir, 14(18), 5195-5202.

Sowerby, S. J., Edelwirth, M., & Heckl, W. M. (1998). Molecular mechanics simulation of uracil adlayers on molybdenum disulfide and graphite surfaces. Applied Physics A, 66, S649-S653.

Edelwirth, M., Freund, J., Sowerby, S. J., & Heckl, W. M. (1998). Molecular mechanics study of hydrogen bonded self-assembled adenine monolayers on graphite. Surface Science, 417, 201-209.

Sowerby, S. J., & Petersen, G. B. (1997). Scanning Tunneling microscopy of uracil monolayers self-assembled at the solid/liquid interface. Journal of Electroanalytical Chemistry, 433(1-2), 85-90.

Sowerby, S. J., Heckl, W. M., & Petersen, G. B. (1996). Chiral symmetry breaking during the self-assembly of monolayers from achiral purine molecules. Journal of Molecular Evolution, 43(5), 419-424.

Sowerby, S. J., Kennedy, M. A., Fitzgerald, P. H., & Morris, C. M. (1993). DNA sequence analysis of the major breakpoint cluster region of the BCR gene rearranged in Philadelphia-positive human leukemias. Oncogene, 8(6), 1679-1683.

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Journal - Research Other

Hoekendijk, D. J. L., Hill, P. C., & Sowerby, S. J. (2016). Rationale for quality assurance in fecal egg monitoring of soil-transmitted helminthiasis [Perspective]. American Journal of Tropical Medicine & Hygiene, 95(3), 502-504. doi: 10.4269/ajtmh.15-0463

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