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Otago Medical School staff profiles

Associate Professor Katrina Sharples

PositionResearch Associate Professor
DepartmentDepartment of Medicine (Dunedin)
QualificationsMSc(Auck) PhD(Wash)
Research summaryBiostatistics

Research

Katrina is a biostatictician who has worked in conjunction with many different researchers and on different areas of research in preventive medicine and other disciplines including the AIDS Epidemiology Group.

Publications

Parkin, L., Sharples, K. J., Barson, D. J., & Blank, M.-L. (2017). Simvastatin dose and acute kidney injury without concurrent serious muscle injury: A nationwide nested case-control study. PLoS ONE, 12(7), e0182066. doi: 10.1371/journal.pone.0182066

Burns, K. E., Lo, W.-Y., Findlay, M. P., Sharples, K., Laking, G., & Helsby, N. A. (2016). High CYP2C19 phenotypic variability in gastrointestinal cancer patients. Cancer Chemotherapy & Pharmacology, 77, 195-204. doi: 10.1007/s00280-015-2923-4

Perez, D., Sharples, K. J., Broom, R., Jeffery, M., Proctor, J., Hinder, V., … Simpson, A., … Findlay, M. (2015). A randomised phase IIb trial to assess the efficacy of ReCharge ice cream in preventing chemotherapy-induced diarrhoea. Supportive Care in Cancer, 23(11), 3307-3315. doi: 10.1007/s00520-015-2755-0

Parkin, L., Sharples, K., Hernandez, R. K., & Jick, S. S. (2011). Risk of venous thromboembolism in users of oral contraceptives containing drospirenone or levonorgestrel: Nested case-control study based on UK General Practice Research Database. BMJ, 342, d2139. doi: 10.1136/bmj.d2139

Broom, R. J., Hinder, V., Sharples, K., Proctor, J., Duffey, S., Pollard, S., … Findlay, M. P. N. (2015). Everolimus and zoledronic acid in patients with renal cell carcinoma with bone metastases: A randomized first-line phase II trial. Clinical Genitourinary Cancer, 13(1), 50-58. doi: 10.1016/j.clgc.2014.07.002

Journal - Research Article

Parkin, L., Sharples, K. J., Barson, D. J., & Blank, M.-L. (2017). Simvastatin dose and acute kidney injury without concurrent serious muscle injury: A nationwide nested case-control study. PLoS ONE, 12(7), e0182066. doi: 10.1371/journal.pone.0182066

McKergow, E., Parkin, L., Barson, D. J., Sharples, K. J., & Wheeler, B. J. (2017). Demographic and regional disparities in insulin pump utilization in a setting of universal funding: A New Zealand nationwide study. Acta Diabetologica, 54(1), 63-71. doi: 10.1007/s00592-016-0912-7

van Roode, T., Sharples, K., Dickson, N., & Paul, C. (2017). Life-course relationship between socioeconomic circumstances and timing of first birth in a birth cohort. PLoS ONE, 12(1), e0170170. doi: 10.1371/journal.pone.0170170

Firth, M. J., Sharples, K. J., Hinder, V. A., Macapagal, J., Sarfati, D., Derrett, S. L., … Atmore, C., Keating, J. P., Jeffery, M., … Jackson, C. G. C. A., & Findlay, M. P. N. (2016). Methods of a national colorectal cancer cohort study: The PIPER Project. New Zealand Medical Journal, 129(1440), 25-36. Retrieved from https://www.nzma.org.nz/journal

Burns, K. E., Lo, W.-Y., Findlay, M. P., Sharples, K., Laking, G., & Helsby, N. A. (2016). High CYP2C19 phenotypic variability in gastrointestinal cancer patients. Cancer Chemotherapy & Pharmacology, 77, 195-204. doi: 10.1007/s00280-015-2923-4

Broom, R. J., Hinder, V., Sharples, K., Proctor, J., Duffey, S., Pollard, S., … Findlay, M. P. N. (2015). Everolimus and zoledronic acid in patients with renal cell carcinoma with bone metastases: A randomized first-line phase II trial. Clinical Genitourinary Cancer, 13(1), 50-58. doi: 10.1016/j.clgc.2014.07.002

Perez, D., Sharples, K. J., Broom, R., Jeffery, M., Proctor, J., Hinder, V., … Simpson, A., … Findlay, M. (2015). A randomised phase IIb trial to assess the efficacy of ReCharge ice cream in preventing chemotherapy-induced diarrhoea. Supportive Care in Cancer, 23(11), 3307-3315. doi: 10.1007/s00520-015-2755-0

Moore, A. E., Muirhead, J. C., Sharples, K., & Stringer, M. D. (2014). The effect of upper limb position on ultrasonographic arterial flow to the ulnar nerve. Anaesthesia, 69(4), 356-361. doi: 10.1111/anae.12543

Harvey, V. J., Sharples, K. J., Isaacs, R. J., Jameson, M. B., Jeffery, G. M., McLaren, B. R., … Simpson, A. B., … Findlay, M. P. (2013). A randomized phase II study comparing capecitabine alone with capecitabine and oral cyclophosphamide in patients with advanced breast cancer-cyclox II. Annals of Oncology, 24(7), 1828-1834. doi: 10.1093/annonc/mdt065

Konings, A. F., Martin, L. W., Sharples, K. J., Roddam, L. F., Latham, R., Reid, D. W., & Lamont, I. L. (2013). Pseudomonas aeruginosa uses multiple pathways to acquire iron during chronic infection in cystic fibrosis lungs. Infection & Immunity, 81(8), 2697-2704. doi: 10.1128/IAI.00418-13

Saha, D., Akinsola, A., Sharples, K., Adeyemi, M. O., Antonio, M., Imran, S., … Hill, P. C. (2013). Health Care Utilization and Attitudes Survey: Understanding diarrheal disease in rural Gambia. American Journal of Tropical Medicine & Hygiene, 89(Suppl. 1), 13-20. doi: 10.4269/ajtmh.12-0751

Stringer, M. D., Fraser, S., Gordon, K. C., Sharples, K., & Windsor, J. A. (2013). Gallstones in New Zealand: Composition, risk factors and ethnic differences. ANZ Journal of Surgery, 83(7-8), 575-580. doi: 10.1111/j.1445-2197.2012.06234.x

Cameron, C. M., Coppell, K. J., Fletcher, D. J., & Sharples, K. J. (2012). Capture-recapture using multiple data sources: Estimating the prevalence of diabetes. Australian & New Zealand Journal of Public Health, 36(3), 223-228. doi: 10.1111/j.1753-6405.2012.00868.x

Saxton, P. J. W., Dickson, N. P., McAllister, S. M., Hughes, A. J., & Sharples, K. (2012). HIV prevalence among men who have sex with men in New Zealand 1985-2009: 25 years of public health monitoring. International Journal of STD & AIDS, 23(4), 274-279. doi: 10.1258/ijsa.2011.011213

van Roode, T., Dickson, N., Sharples, K., & Paul, C. (2012). Patterns of sexual partnering and reproductive history: Associations with timing of first birth in a birth cohort. Perspectives on Sexual & Reproductive Health, 44(1), 48-56. doi: 10.1363/4404812

O'Sullivan, P., Sharples, K., Dalphin, M., Davidson, P., Gilling, P., Cambridge, L., … Luxmanan, C., … Yoon, H.-S., … Guilford, P. J. (2012). A multigene urine test for the detection and stratification of bladder cancer in patients presenting with hematuria. Journal of Urology, 188(3), 741-747. doi: 10.1016/j.juro.2012.05.003

Dickson, N. P., McAllister, S., Sharples, K., & Paul, C. (2012). Late presentation of HIV infection among adults in New Zealand: 2005-2010. HIV Medicine, 13(3), 182-189. doi: 10.1111/j.1468-1293.2011.00959.x

Saxton, P. J. W., Dickson, N. P., McAllister, S. M., Sharples, K., & Hughes, A. J. (2011). Increase in HIV diagnoses among men who have sex with men in New Zealand from a stable low period. Sexual Health, 8(3), 311-318. doi: 10.1071/SH10087

Martin, L. W., Reid, D. W., Sharples, K. J., & Lamont, I. L. (2011). Pseudomonas siderophores in the sputum of patients with cystic fibrosis. Biometals, 24(6), 1059-1067. doi: 10.1007/s10534-011-9464-z

Murray, M., Brown, J., Hinder, V., Merrie, A., Hill, A., Hulme-Moir, M., Sharples, K., & Findlay, M. (2011). The colorectal cancer patients' journey: The Auckland region. New Zealand Medical Journal, 124(1331). Retrieved from http://journal.nzma.org.nz/journal

Parkin, L., Sharples, K., Hernandez, R. K., & Jick, S. S. (2011). Risk of venous thromboembolism in users of oral contraceptives containing drospirenone or levonorgestrel: Nested case-control study based on UK General Practice Research Database. BMJ, 342, d2139. doi: 10.1136/bmj.d2139

Al-Mahrouqi, H., Parkin, L., & Sharples, K. (2011). Incidence of stomach cancer in Oman and the other Gulf Cooperation Council countries. Oman Medical Journal, 26(4), 258-262. doi: 10.5001/omj.2011.62

McCredie, M. R. E., Paul, C., Sharples, K. J., Baranyai, J., Medley, G., Skegg, D. C. G., & Jones, R. W. (2010). Consequences in women of participating in a study of the natural history of cervical intraepithelial neoplasia 3. Australian & New Zealand Journal of Obstetrics & Gynaecology, 50(4), 363-370. doi: 10.1111/j.1479-828X.2010.01170.x

Stewart, R. A. H., North, F. M., Sharples, K. J., Simes, R. J., Tonkin, A. M., White, H. D., for the Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Investigators. (2008). Differences in cardiovascular mortality between Australia and New Zealand according to socioeconomic status: findings from the Long-term Intervention with Pravastatiin in Ischaemic Disease (LIPID) study. New Zealand Medical Journal, 121(1269). Retrieved from http://journal.nzma.org.nz/journal

McAllister, S. M., Dickson, N. P., Sharples, K., Reid, M. R., Morgan, J. M., MacDonald, E. J., Coughlan, E., … Paul, C. (2008). Unlinked anonymous HIV prevalence among New Zealand sexual health clinic attenders: 2005-2006. International Journal of STD & AIDS, 19(11), 752-757.

Fleming, T. R., Sharples, K., McCall, J., Moore, A., Rodgers, A., & Stewart, R. (2008). Maintaining confidentiality of interim data to enhance trial integrity and credibility. Clinical Trials, 5, 157-167. doi: 10.1177/1740774508089459

Furneaux, C. C., Marshall, E. S., Yeoh, K., Monteith, S. J., Mews, P. J., Sansur, C. A., … Sharples, K. J., & Baguley, B. C. (2008). Cell cycle times of short-term cultures of brain cancers as predictors of survival. British Journal of Cancer, 99(10), 1678-1683.

Helsby, N. A., Lo, W.-Y., Sharples, K., Riley, G., Murray, M., Spells, K., … Findlay, M. (2008). CYP2C19 pharmacogenetics in advanced cancer: Compromised function independent of genotype. British Journal of Cancer, 99(8), 1251-1255.

McCredie, M. R. E., Sharples, K. J., Paul, C., Baranyai, J., Medley, G., Jones, R. W., & Skegg, D. C. G. (2008). Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial neoplasia 3: A retrospective cohort study. Lancet Oncology, 9(5), 425-434. doi: 10.1016/S1470-2045(08)70103-7

Findlay, M., Sharples, K., Riley, G., Simpson, A., Ackland, S., Hall, K., … McKeage, M. J. (2007). Capecitabine and oral cyclophosphamide: A novel oral treatment combination for advanced cancer. Asia-Pacific Journal of Clinical Oncology, 3, 99-105. doi: 10.1111/j.1743-7563.2007.00095.x

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Journal - Research Other

Jackson, C., McCall, J., Robinson, B., Sharples, K., & Findlay, M. (2013). Cancer trials in New Zealand: Patients are not the problem. New Zealand Medical Journal, 126(1381). Retrieved from http://www.nzma.org.nz/journal

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