Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Otago Medical School staff profiles

Professor Patrick Manning

PositionClinical Professor of Medicine; Consultant Endocrinologist; Director, Endocrinology Research Group
DepartmentDepartment of Medicine (Dunedin)
QualificationsBHB MB ChB MMedSci FRACP
Research summaryEndocrinology and diabetes.

Research

The Endocrinology Research Group's major focus relates to clinical trials in all areas of endocrinology including diabetes, general endocrinology, and metabolism. A key area of research focus is the link between obesity and insulin resistance.

The group has published widely on the effect of meal composition on postprandial inflammation and is involved in clinical trials in obesity, type 2 diabetes and osteoporosis.

The group consists of Prof Patrick Manning, Dr Wayne Sutherland, Dr Ted Nye, and is assisted by three research nurses (Anne Ryalls, Liz Berry and Gavin Hendry). In addition the group has collaborative projects with other members of the Department of Medicine, as well as other researchers both nationally and internationally.

Opportunities

If you have research interest in clinical endocrinology including diabetes and/or obesity and have either a tertiary science degree or a medical degree then feel free to make contact with Prof Patrick Manning to find out if there are any current research opportunities available within the research group.

Otago Kidney Research

Publications

Manning, P., Munasinghe, P. E., Bellae Papannarao, J., Gray, A. R., Sutherland, W., & Katare, R. (2019). Acute weight loss restores dysregulated circulating microRNAs in obese individuals. Journal of Clinical Endocrinology & Metabolism, 104(4), 1239-1248. doi: 10.1210/jc.2018-00684

Manning, P. J., Grattan, D., Merriman, T., Manning, T., Williams, S., & Sutherland, W. (2018). Pharmaceutical interventions for weight-loss maintenance: No effect from cabergoline. International Journal of Obesity. Advance online publication. doi: 10.1038/s41366-018-0165-3

Ma, Z. F., Venn, B. J., Manning, P. J., Cameron, C. M., & Skeaff, S. A. (2018). The sensitivity and specificity of thyroglobulin concentration using repeated measures of urinary iodine excretion. European Journal of Nutrition, 57(4), 1313-1320. doi: 10.1007/s00394-017-1410-6

Leong, S. L., Vanneste, S., Lim, J., Smith, M., Manning, P., & De Ridder, D. (2018). A randomised, double-blind, placebo-controlled parallel trial of closed-loop infraslow brain training in food addiction. Scientific Reports, 8, 11659. doi: 10.1038/s41598-018-30181-7

Leong, S. L., De Ridder, D., Vanneste, S., Sutherland, W., Ross, S., & Manning, P. (2018). High definition transcranial pink noise stimulation of anterior cingulate cortex on food craving: An explorative study. Appetite, 120, 673-678. doi: 10.1016/j.appet.2017.10.034

Chapter in Book - Research

De Ridder, D., Manning, P., Cape, G., Vanneste, S., Langguth, B., & Glue, P. (2016). Pathophysiology-based neuromodulation for addictions: An overview. In V. R. Preedy (Ed.), Neuropathology of drug addictions and substance misuse (Vol. 1: Foundations of understanding, tobacco, alcohol, cannabinoids and opioids). (pp. 14-24). London: Elsevier. doi: 10.1016/B978-0-12-800213-1.00002-X

^ Top of page

Journal - Research Article

Manning, P., Munasinghe, P. E., Bellae Papannarao, J., Gray, A. R., Sutherland, W., & Katare, R. (2019). Acute weight loss restores dysregulated circulating microRNAs in obese individuals. Journal of Clinical Endocrinology & Metabolism, 104(4), 1239-1248. doi: 10.1210/jc.2018-00684

Manning, P. J., Grattan, D., Merriman, T., Manning, T., Williams, S., & Sutherland, W. (2018). Pharmaceutical interventions for weight-loss maintenance: No effect from cabergoline. International Journal of Obesity. Advance online publication. doi: 10.1038/s41366-018-0165-3

Leong, S. L., De Ridder, D., Vanneste, S., Sutherland, W., Ross, S., & Manning, P. (2018). High definition transcranial pink noise stimulation of anterior cingulate cortex on food craving: An explorative study. Appetite, 120, 673-678. doi: 10.1016/j.appet.2017.10.034

Leong, S. L., Vanneste, S., Lim, J., Smith, M., Manning, P., & De Ridder, D. (2018). A randomised, double-blind, placebo-controlled parallel trial of closed-loop infraslow brain training in food addiction. Scientific Reports, 8, 11659. doi: 10.1038/s41598-018-30181-7

Ma, Z. F., Venn, B. J., Manning, P. J., Cameron, C. M., & Skeaff, S. A. (2018). The sensitivity and specificity of thyroglobulin concentration using repeated measures of urinary iodine excretion. European Journal of Nutrition, 57(4), 1313-1320. doi: 10.1007/s00394-017-1410-6

Wilson, L. C., Peebles, K. C., Hoye, N. A., Manning, P., Sheat, C., Williams, M. J. A., Wilkins, G. T., Wilson, G. A., & Baldi, J. C. (2017). Resting heart rate variability and exercise capacity in Type 1 diabetes. Physiological Reports, 5(8), e13248. doi: 10.14814/phy2.13248

Rawal, S., Munasinghe, P. E., Shindikar, A., Paulin, J., Cameron, V., Manning, P., Williams, M. J. A., Jones, G. T., Bunton, R., Galvin, I., & Katare, R. (2017). Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. Cardiovascular Research, 113(1), 90-101. doi: 10.1093/cvr/cvw235

Rawal, S., Munasinghe, E. P., Nagesh, P. T., Lew, J. K. S., Jones, G. T., Williams, M. J. A., Davis, P., Bunton, R. W., Galvin, I. F., Manning, P., Lamberts, R. R., & Katare, R. (2017). Downregulation of miR-15a/b accelerates fibrotic remodelling in the Type-2 diabetic human and mouse heart. Clinical Science, 131(9), 847-863. doi: 10.1042/cs20160916

Williams, K. H., Sullivan, D. R., Nicholson, G. C., George, J., Jenkins, A. J., Januszewski, A. S., … Manning, P., … Keech, A. C. (2016). Opposite associations between alanine aminotransferase and γ-glutamyl transferase levels and all-cause mortality in type 2 diabetes: Analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Metabolism, 65(5), 783-793. doi: 10.1016/j.metabol.2015.12.008

De Ridder, D., Vanneste, S., Gillett, G., Manning, P., Glue, P., & Langguth, B. (2016). Psychosurgery reduces uncertainty and increases free will? A review. Neuromodulation, 19, 239-248. doi: 10.1111/ner.12405

De Ridder, D., Manning, P., Leong, S. L., Ross, S., & Vanneste, S. (2016). Allostasis in health and food addiction. Scientific Reports, 6, 37126. doi: 10.1038/srep37126

De Ridder, D., Manning, P., Leong, S. L., Ross, S., Sutherland, W., Horwath, C., & Vanneste, S. (2016). The brain, obesity and addiction: An EEG neuroimaging study. Scientific Reports, 6, 34122. doi: 10.1038/srep34122

Ma, Z. F., Venn, B. J., Manning, P. J., Cameron, C. M., & Skeaff, S. A. (2016). Iodine supplementation of mildly iodine-deficient adults lowers thyroglobulin: A randomized controlled trial. Journal of Clinical Endocrinology & Metabolism, 101(4), 1737-1744. doi: 10.1210/jc.2015-3591

Holdaway, I. M., Hunt, P., Manning, P., Cutfield, W., Gamble, G., Ninow, N., … Metcalfe, S. (2015). Three-year experience with access to nationally funded growth hormone (GH) replacement for GH-deficient adults. Clinical Endocrinology, 83(1), 85-90. doi: 10.1111/cen.12691

Evans, M. C., Clark, V. W., Manning, P. J., De Ridder, D., & Reynolds, J. N. J. (2015). Optimizing deep brain stimulation of the nucleus accumbens in a reward preference rat model. Neuromodulation, 18(7), 531-541. doi: 10.1111/ner.12339

Rawal, S., Manning, P., & Katare, R. (2014). Cardiovascular microRNAs: As modulators and diagnostic biomarkers of diabetic heart disease. Cardiovascular Diabetology, 13, 44. doi: 10.1186/1475-2840-13-44

Francois, M. E., Baldi, J. C., Manning, P. J., Lucas, S. J. E., Hawley, J. A., Williams, M. J. A., & Cotter, J. D. (2014). ‘Exercise snacks’ before meals: A novel strategy to improve glycaemic control in individuals with insulin resistance. Diabetologia, 57(7), 1437-1445. doi: 10.1007/s00125-014-3244-6

Manning, P. J., Sutherland, W. H. F., Williams, S. M., Walker, R. J., Berry, E. A., De Jong, S. A., & Ryalls, A. R. (2013). The effect of lipoic acid and vitamin E therapies in individuals with the metabolic syndrome. Nutrition, Metabolism & Cardiovascular Diseases, 23(6), 543-549. doi: 10.1016/j.numecd.2011.11.006

Manning, P. J., Sutherland, W. H. F., Williams, S. M., de Jong, S. A., & Hendry, G. P. (2013). Oral but not intravenous glucose acutely decreases circulating interleukin-6 concentrations in overweight individuals. PLoS ONE, 8(6), e66395. doi: 10.1371/journal.pone.0066395

Latta, L., Tordoff, D., Manning, P., & Dent, J. (2013). Enhancing clinical skill development through an Ambulatory Medicine Teaching Programme: An evaluation study. Medical Teacher, 35(8), 648-654. doi: 10.3109/0142159X.2013.801553

Vos, F. E., Schollum, J. B., Coulter, C. V., Manning, P. J., Duffull, S. B., & Walker, R. J. (2012). Assessment of markers of glycaemic control in diabetic patients with chronic kidney disease using continuous glucose monitoring. Nephrology, 17(2), 182-188. doi: 10.1111/j.1440-1797.2011.01517.x

Manning, P. J., De Jong, S. A., Ryalls, A. R., & Sutherland, W. H. F. (2012). Paraoxonase 1 activity in chylomicrons and VLDL: The effect of type 2 diabetes and meals rich in saturated fat and oleic acid. Lipids, 47(3), 259-267. doi: 10.1007/s11745-011-3640-3

Silverman, S. L., Chines, A. A., Kendler, D. L., Kung, A. W. C., Teglbjærg, C. S., Felsenberg, D., … for the Bazedoxifene Study Group, including Manning, P. (2012). Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: Results of a 5-year, randomized, placebo-controlled study. Osteoporosis International, 23(1), 351-363. doi: 10.1007/s00198-011-1691-1

Sullivan, D., Forder, P., Simes, J., Whiting, M., Kritharides, L., Merrifield, A., … for the FIELD Study Investigators, including Manning, P. (2011). Associations between the use of metformin, sulphonylureas, or diet alone and cardiovascular outcomes in 6005 people with type 2 diabetes in the FIELD study. Diabetes Research & Clinical Practice, 94(2), 284-290. doi: 10.1016/j.diabres.2011.07.028

Sosenko, J. M., Skyler, J. S., Palmer, J. P., Krischer, J. P., Cuthbertson, D., Yu, L., … Diabetes Prevention Trial-Type 1, and Type 1 Diabetes TrialNet Study Groups, including Manning, P. (2011). A longitudinal study of GAD65 and ICA512 autoantibodies during the progression to type 1 diabetes in Diabetes Prevention Trial-Type 1 (DPT-1) participants. Diabetes Care, 34(11), 2435-2437. doi: 10.2337/dc11-0981

Scott, R., Donoghoe, M., Watts, G. F., O'Brien, R., Pardy, C., Taskinen, M.-R., … Manning, P., … Keech, A. C. (2011). Impact of metabolic syndrome and its components on cardiovascular disease event rates in 4900 patients with type 2 diabetes assigned to placebo in the FIELD randomised trial. Cardiovascular Diabetology, 10, 102. doi: 10.1186/1475-2840-10-102

Davis, T. M. E., Ting, R. D., Best, J. D., Donoghoe, M. W., Drury, P. L., Sullivan, D. R., … on behalf of the FIELD Study Investigators, including Manning, P. (2011). Effects of fenofibrate on renal function in patients with type 2 diabetes mellitus: The fenofibrate intervention and event lowering in diabetes (FIELD) study. Diabetologia, 54(2), 280-290. doi: 10.1007/s00125-010-1951-1

Vehik, K., Cuthbertson, D., Ruhlig, H., Schatz, D. A., Peakman, M., Krischer, J. P., for the DPT-1 and TrialNet Study Groups, including Manning, P. (2011). Long-term outcome of individuals treated with oral insulin: Diabetes Prevention Trial-Type 1 (DPT-1) oral insulin trial. Diabetes Care, 34(7), 1585-1590. doi: 10.2337/dc11-0523

Slade, H., Williams, S. M., Manning, P. J., & Walker, R. J. (2011). High-risk diabetic nephropathy patients: The outcome of evidence-based clinical practice in an outpatient clinic. Diabetes Research & Clinical Practice, 92(3), 356-360. doi: 10.1016/j.diabres.2011.02.022

Vehik, K., Beam, C. A., Mahon, J. L., Schatz, D. A., Haller, M. J., Sosenko, J. M., … for the TrialNet Natural History Study Group, including Manning, P. (2011). Development of autoantibodies in the TrialNet Natural History study. Diabetes Care, 34(9), 1897-1901. doi: 10.2337/dc11-0560

Sosenko, J. M., Skyler, J. S., Mahon, J., Krischer, J. P., Beam, C. A., Boulware, D. C., … the Type 1 Diabetes TrialNet and Diabetes Prevention Trial-Type 1 Study Groups, including Manning, P. (2011). Validation of the Diabetes Prevention Trial-Type 1 risk score in the TrialNet Natural History study. Diabetes Care, 34(8), 1785-1787. doi: 10.2337/dc11-0641

Sosenko, J. M., Mahon, J., Rafkin, L., Lachin, J. M., Krause-Steinrauf, H., Krischer, J. P., … and the Diabetes Prevention Trial-Type 1 and TrialNet Study Groups, including Manning, P. (2011). A comparison of the baseline metabolic profiles between Diabetes Prevention Trial-Type 1 and TrialNet Natural History study participants. Pediatric Diabetes, 12(2), 85-90. doi: 10.1111/j.1399-5448.2010.00662.x

Vos, F. E., Manning, P. J., Sutherland, W. H. F., Schollum, J. B., & Walker, R. J. (2011). Anti-inflammatory effect of an insulin infusion in patients on maintenance haemodialysis: A randomized controlled pilot study. Nephrology, 16(1), 68-75. doi: 10.1111/j.1440-1797.2010.01329.x

Taylor, R. W., Brooking, L., Williams, S. M., Manning, P. J., Sutherland, W. H., Coppell, K. J., Tipene-Leach, D., Dale, K. S., McAuley, K. A., & Mann, J. I. (2010). Body mass index and waist circumference cutoffs to define obesity in indigenous New Zealanders. American Journal of Clinical Nutrition, 92, 390-397. doi: 10.3945/ajcn.2010.29317

Taskinen, M.-R., Barter, P. J., Ehnholm, C., Sullivan, D. R., Mann, K., Simes, J., … on behalf of the FIELD Study Investigators, including Manning, P. (2010). Ability of traditional lipid ratios and apolipoprotein ratios to predict cardiovascular risk in people with type 2 diabetes. Diabetologia, 53(9), 1846-1855. doi: 10.1007/s00125-010-1806-9

Simes, J., Voysey, M., O'Connell, R., Glasziou, P., Best, J. D., Scott, R., … for the FIELD Study Investigators, including Manning, P. (2010). A novel method to adjust efficacy estimates for uptake of other active treatments in long-term clinical trials. PLoS ONE, 5(1), e8580. doi: 10.1371/journal.pone.0008580

Mahon, J. L., Sosenko, J. M., Rafkin-Mervis, L., Krause-Steinrauf, H., Lachin, J. M., Thompson, C., … for the TrialNet Natural History Committee, and Type 1 Diabetes TrialNet Study Group, including Manning, P. (2009). The TrialNet Natural History study of the development of type 1 diabetes: Objectives, design, and initial results. Pediatric Diabetes, 10(2), 97-104. doi: 10.1111/j.1399-5448.2008.00464.x

Scott, R., O'Brien, R., Fulcher, G., Pardy, C., D'Emden, M., Tse, D., … on behalf of the Fenofibrate Intervention and Event Lowering in Diabete (FIELD) Study Investigators, including Manning, P. (2009). Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome. Diabetes Care, 32(3), 493-498. doi: 10.2337/dc08-1543

Taskinen, M.-R., Sullivan, D. R., Ehnholm, C., Whiting, M., Zannino, D., Simes, R. J., … for the FIELD Study Investigators, including Manning, P. (2009). Relationships of HDL cholesterol, ApoA-I, and ApoA-II with homocysteine and creatinine in patients with type 2 diabetes treated with fenofibrate. Arteriosclerosis, Thrombosis, & Vascular Biology, 29, 950-955. doi: 10.1161/ATVBAHA.108.178228

Herold, K. C., Brooks-Worrell, B., Palmer, J., Dosch, H. M., Peakman, M., Gottlieb, P., … and the Type 1 Diabetes TrialNet Research Group, including Manning, P. (2009). Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes. Diabetes, 58(11), 2588-2595. doi: 10.2337/db09-0249

Rajamani, K., Colman, P. G., Li, L. P., Best, J. D., Voysey, M., D'Emden, M. C., … on behalf of the FIELD Study Investigators, including Manning, P. (2009). Effect of fenofibrate on amputation events in people with type 2 diabetes mellitus (FIELD study): A prespecified analysis of a randomised controlled trial. Lancet, 373(9677), 1780-1788. doi: 10.1016/S0140-6736(09)60698-X

Manning, P. J., Sutherland, W. H. F., Walker, R. J., Williams, S. M., de Jong, S. A., & Berry, E. A. (2008). The effect of rosiglitazone on oxidative stress and insulin resistance in overweight individuals. Diabetes Research & Clinical Practice, 81, 209-215.

Manning, P. J., Sutherland, W. H. F., Walker, R. J., de Jong, S. A., & Berry, E. A. (2008). The effect of glucose ingestion on inflammation and oxidative stress in obese individuals. Metabolism, 57, 1345-1349.

Greenbaum, C., Mandrup-Poulsen, T., McGee, P. F., Battelino, T., Haastert, B., Ludvigsson, J., … the Type 1 Diabetes TrialNet Research Group, and the European C-Peptide Trial Study Group, including Manning, P. (2008). Mixed-meal tolerance test versus glucagon stimulation test for the assessment of β-cell function in therapeutic trials in type 1 diabetes. Diabetes Care, 31(10), 1966-1971. doi: 10.2337/dc07-2451

Manning, P. J., Sutherland, W. H. F., McGrath, M. M., de Jong, S. A., Walker, R. J., & Williams, M. J. A. (2008). Postprandial cytokine concentrations and meal composition in obese and lean women. Obesity, 16(9), 2046-2052. doi: 10.1038/oby.2008.334

Sutherland, W. H. F., Manning, P. J., Walker, R. J., de Jong, S. A., Ryalls, A. R., & Berry, E. A. (2007). Vitamin E supplementation and plasma 8-isoprostane and adiponectin in overweight subjects. Obesity, 15(2), 386-391. doi: 10.1038/oby.2007.546

Helge, J. W., Rehrer, N. J., Pilegaard, H., Manning, P., Lucas, S. J. E., Gerrard, D. F., & Cotter, J. D. (2007). Increased fat oxidation and regulation of metabolic genes with ultraendurance exercise. Acta Physiologica, 191, 77-86.

Keech, A. C., Mitchell, P., Summanen, P. A., O'Day, J., Davis, T. M. E., Moffitt, M. S., … for the FIELD Study Investigators, including Manning, P. (2007). Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): A randomised controlled trial. Lancet, 370(9600), 1687-1697. doi: 10.1016/S0140-6736(07)61607-9

Florkowski, C. M., Brownlie, B. E. W., Croxson, M. S., Manning, P., Farrand, S., Smith, G., … George, P. M. (2006). Thyroid hormone resistance: The role of mutational analysis. Internal Medicine Journal, 36, 738-741.

Coppell, K. J., Anderson, K., Williams, S., Manning, P., & Mann, J. (2006). Evaluation of diabetes care in the Otago region using a diabetes register, 1998-2003. Diabetes Research & Clinical Practice, 71, 345-352.

O'Connell, R., Parkin, L., Manning, P., Bell, D., Herbison, P., & Holmes, J. (2005). A cluster of thyrotoxicosis associated with consumption of a soy milk product. Australian & New Zealand Journal of Public Health, 29(6), 511-512. doi: 10.1111/j.1467-842X.2005.tb00240.x

Adams, D. D., Knight, J. G., Manning, P., & Smith, G. (2005). An informative case of Graves' disease with implications for schizophrenia. Journal of Clinical & Laboratory Immunology, 53, 13-25.

Markou, A., Manning, P., Kaya, B., Datta, S. N., Bomanji, J. B., & Conway, G. S. (2005). [18F]fluoro-2-deoxy-D-glucose ([18F]FDG) positron emission tomography imaging of thymic carcinoid tumor presenting with recurrent Cushing's syndrome. European Journal of Endocrinology, 152(4), 521-525.

Goulding, A., Jones, I. E., Williams, S. M., Grant, A. M., Taylor, R. W., Manning, P. J., & Langley, J. (2005). First fracture is associated with increased risk of new fractures during growth. Journal of Pediatrics, 146, 286-288.

Manning, P. J., Sutherland, W. H., Walker, R. J., Williams, S. M., de Jong, S. A., Ryalls, A. R., & Berry, E. A. (2004). Effect of high-dose vitamin E on insulin resistance and associated parameters in overweight subjects. Diabetes Care, 27(9), 2166-2171.

Manning, P. J., Sutherland, W. H., Hendry, G., de Jong, S. A., McGrath, M., & Williams, S. M. (2004). Changes in circulating postprandial proinflammatory cytokine concentrations in diet-controlled type 2 diabetes and the effect of ingested fat. Diabetes Care, 27(10), 2509-2511.

Manning, P. J., Espiner, E. A., Yoon, K., Drury, P. L., Holdaway, I. M., & Bowers, A. J. (2003). An unusual cause of hyperinsulinaemic hypoglycaemia syndrome. Diabetic Medicine, 20, 772-776.

Hall, R. J., Merriman, M. E., Green, R. A., Markham, V. H., Smyth, D. J., Heward, J. M., … Braithwaite, A., … Darlow, B. A., … Harrison, A. A., Highton, J., Hunt, P. J., Manning, P. J., … Scott, R. S., Taylor, B. J., Willis, J., … Merriman, T. R. (2003). The Deleted in Colorectal Carcinoma (DCC) gene 201 R → G polymorphism: No evidence for genetic association with autoimmune disease. European Journal of Human Genetics, 11, 840-844.

Manning, P. J., Sutherland, W. H. F., Allum, A. R., de Jong, S. A., & Jones, S. (2003). HRT does not improve urinary albumen excretion in postmenopausal diabetic women. Diabetes Research & Clinical Practice, 60(1), 33-39.

Coppell, K., & Manning, P. J. (2002). Establishing a regional diabetes register and a description of the registered population after one year. New Zealand Medical Journal, 115(1160), U146. Retrieved from http://www.nzma.org.nz/journal/

Goulding, A., Taylor, R. W., Jones, I. E., Manning, P. J., & Williams, S. M. (2002). Spinal overload: A concern for obese children and adolescents? Osteoporosis International, 13, 835-840.

Manning, P. J., Sutherland, W. H. F., Allum, A. R., de Jong, S. A., & Jones, S. D. (2002). The effect of hormone replacement therapy on inflammation-sensitive proteins in post-menopausal women with Type 2 diabetes. Diabetic Medicine, 19(10), 847-852. doi: 10.1046/j.1464-5491.2002.00808.x

Jones, I. E., Taylor, R. W., Williams, S. M., Manning, P. J., & Goulding, A. (2002). Four-year gain in bone mineral in girls with and without past forearm fractures: A DXA study. Journal of Bone & Mineral Research, 17(6), 1065-1072.

Manning, P. J., Allum, A., Jones, S., Sutherland, W. H. F., & Williams, S. M. (2001). The effect of hormone replacement therapy on cardiovascular risk factors in type 2 diabetes: A randomised controlled trial. Archives of Internal Medicine, 161, 1772-1776.

Sutherland, W. H., Manning, P. J., de Jong, S. A., Allum, A. R., Jones, S. D., & Williams, S. M. (2001). Hormone replacement therapy increases serum paraoxonase arylesterase activity in diabetic postmenopausal women. Metabolism, 50, 319-324.

Hip Intervention Program Study, & Manning, P. J. (2001). Effect of risedronate on the risk of hip fracture in elderly women. New England Journal of Medicine, 344(5), 333-340.

Goulding, A., Jones, I. E., Taylor, R. W., Williams, S. M., & Manning, P. J. (2001). Bone mineral density and body composition in boys with distal forearm fractures: A dual-energy x-ray absorptiometry study. Journal of Pediatrics, 139(4), 509-515.

Goulding, A., Taylor, R. W., Jones, I. E., McAuley, K. A., Manning, P. J., & Williams, S. M. (2000). Overweight and obese children have low bone mass and area for their weight. International Journal of Obesity, 24, 627-632.

McBain, L., McLeod, D., Coppell, K., & Manning, P. J. (2000). Diabetes care in general practice. New Zealand Family Physician, 27(6), 49-60.

Rodby, R. A., Rohde, R. D., Clarke, W. R., Hunsicker, L. G., Anzalone, D. A., Atkins, R. C., … Manning, P. J. (2000). The Ibesarten type 2 diabetic nephropathy trial: Study design and baseline characteristics. Nephrology Dialysis Transplantation, 15(4), 487-497.

Goulding, A., Jones, I. E., Taylor, R. W., Manning, P. J., & Williams, S. M. (2000). More broken bones: A 4-year double cohort study of young girls with and without distal forearm fractures. Journal of Bone & Mineral Research, 15(10), 2011-2018.

McBain, L., McLeod, D., Coppell, K., & Manning, P. (2000). The provision of care for patients with diabetes in general practice. New Zealand Family Physician, 27(26), 49-55.

McAuley, K., Cambridge, L., Galloway, S. M., Sullivan, J. A., & Manning, P. J. (2000). De nono deletion of xq associated with premature ovarian failure. Australian & New Zealand Journal of Medicine, 30, 89-90.

Schwartz, M. M., Lewis, E. J., Leonard-Martin, T., Lewis, J. B., Batlle, D., & Manning, P. J. (1998). Renal pathology patterns in type 2 diabetes mellitis: Relationship with retinopathy: The collaborative study group. Nephrology Dialysis Transplantation, 13(10), 2547-2552.

McAuley, K. A., Jones, S., Lewis-Barned, N. J., Manning, P. J., & Goulding, A. (1997). Low vitamin D status is common among elderly Dunedin women. New Zealand Medical Journal, 110(1048), 275-277.

Manning, P. J., Sutherland, W. H. F., & Mann, J. (1997). Hyperchylomicronaemia might have resolved anyway. British Medical Journal, 314, 65.

Taylor, R. W., Gold, E. J., Manning, P. J., & Goulding, A. (1997). Gender differences in body fat content are present well before puberty. International Journal of Obesity, 21(11), 1082-1084.

Manning, P. J., Sutherland, W. H. F., & Mann, J. (1997). Late diagnosis of diabetic ketoacidosis and underlying disease influence response to treatment. British Medical Journal, 314, 63.

Florkowski, C. M., Holdaway, I. M., Manning, P. J., & Donald, R. A. (1996). The case for growth hormone replacement in adult hypopituitarism. New Zealand Medical Journal, 109, 349-351.

^ Top of page

Journal - Research Other

Oliphant, J., Veale, J., Macdonald, J., Carroll, R., Johnson, R., Harte, M., … Cole, D., & Manning, P. (2018). Guidelines for gender affirming healthcare for gender diverse and transgender children, young people and adults in Aotearoa, New Zealand. New Zealand Medical Journal, 131(1487), 86-96. Retrieved from https://www.nzma.org.nz/journal

Manning, P. (2017). Osteoporosis and osteonecrosis of the jaw. New Zealand Dental Journal, 113(2), 2-3. [Editorial].

De Ridder, D., Leong, S. L., Manning, P., Vanneste, S., & Glue, P. (2017). Anterior cingulate implant for obsessive-compulsive disorder. World Neurosurgery, 97, 754.e7-754.e16. doi: 10.1016/j.wneu.2016.10.046

De Ridder, D., Manning, P., Glue, P., Cape, G., Langguth, B., & Vanneste, S. (2016). Anterior cingulate implant for alcohol dependence. Neurosurgery, 78(6), E883-E893. doi: 10.1227/neu.0000000000001248

Manning, T. E., Manning, A. E., & Manning, P. J. (2015). Systemic capillary leak syndrome: A case-report. New Zealand Medical Journal, 128(1415). Retrieved from https://www.nzma.org.nz/journal

Baldi, J. C., Manning, P. J., Hofman, P. L., & Walker, R. J. (2013). Comment on: TODAY Study Group. Effects of Metformin, Metformin plus Rosiglitazone, and Metformin plus lifestyle on insulin sensitivity and β-cell function in TODAY. Diabetes Care 2013;36:1749-1757 [Comment]. Diabetes Care, 36, e223. doi: 10.2337/dc13-1426

Wheeler, B. J., Patterson, N., Love, D. R., Prosser, D., Tomlinson, P., Taylor, B. J., & Manning, P. (2013). Frequency and genetic spectrum of maturity-onset diabetes of the young (MODY) in southern New Zealand. Journal of Diabetes & Metabolic Disorders, 12, 46. doi: 10.1186/2251-6581-12-46

Choi, A.-R. A., & Manning, P. (2009). Overshooting the mark: Subclinical hyperthyroidism secondary to excess thyroid hormone treatment may be more prevalent than we realise [Letter]. New Zealand Medical Journal, 122(1289). Retrieved from http://journal.nzma.org.nz/journal/122-1289/3473/content.pdf

Astwood, D., Yoon, H.-S., & Manning, P. J. (2006). Hyperandrogenism in a patient with previous colorectal cancer [Letter to the editor]. Internal Medicine Journal, 36(11), 751-752.

Manning, P. J., Sutherland, W. H. F., & Walker, R. J. (2005). Effect of high-dose vitamin E on insulin resistance and associated parameters in overweight subjects [Response to Vale]. Diabetes Care, 28(1), 230-231.

Stott, V., Manning, P., & Hung, N. (2005). Idiopathic granulomatous hypophysitis [Case report]. New Zealand Medical Journal, 118(1211). Retrieved from http://journal.nzma.org.nz/journal/118-1211/1355/content.pdf

More publications...