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Otago Medical School staff profiles

Mr Ivor Galvin

PositionClinical Senior Lecturer
DepartmentDepartment of Surgical Sciences (DSM)
QualificationsMB BCh BAO FRCSI FRACS
Research summaryCoronary artery surgery, surgical techniques
Teaching
  • Cardiothoracic supervisor of training - Dunedin Public Hospital
  • Registrar training
Memberships
  • Examiner in Cardiothoracic Surgery, Courts of Examiners RACS
Clinical
  • Coronary artery surgery and valvular surgery in specific
  • Cardiothoracic surgery in general

Research

I am a principle investigator/clinician on 'Heart Otago'. We are looking at protein analysis, biomarkers, and catecholamine effects on human atrial and ventricular live biopsies.

Recent publications

Saxena, P., Haji Mohd Yasin, N. A. B., & Galvin, I. F. (2013). Lung volume reexpansion surgery: A surgical secret. American Journal of Respiratory & Critical Care Medicine, 187(5), 552. doi: 10.1164/rccm.201209-1645IM

Saxena, P., Chai, P. H., & Galvin, I. (2012). Composite venous coronary grafts: Construction made simple. The Annals of Thoracic Surgery, 93(4), 1324–1325. doi: 10.1016/j.athoracsur.2011.11.069

Galvin, S. D., Wademan, B., & Galvin, I. F. (2012). Pulmonary embolism secondary to metastatic renal cell carcinoma. [Case Reports]. Journal of Cardiac Surgery, 27(6), 707–708. doi: 10.1111/j.1540-8191.2012.01427.x

Galvin, S. D., Ninan, S. B., Lau, G. B., & Galvin, I. F. (2010). Rupture of aortic pseudoaneursym arising from a transverse aortotomy line 12 years following mechanical aortic valve replacement. [Case Reports]. Journal of Cardiac Surgery, 25(5), 563–565. doi: 10.1111/j.1540-8191.2010.01068.x

Galvin, S. D., Celi, L. A. G., Galvin, I. F., & Bunton, R. W. (2011). Use of machine learning algorithms to assess outcomes in patients over 80-years of age undergoing cardiac surgery. Heart, Lung and Circulation, 20(1), 48. doi: 10.1016/j.hlc.2010.10.031

Galvin, I. F., & Galvin, S. D. (2010). Top-end aortocoronary anastomosis made easy: The visor technique. Journal of Cardiac Surgery, 25(5), 511-512. doi: 10.1111/j.1540-8191.2010.01090.x

Publications

Rawal, S., Nagesh, P. T., Coffey, S., Van Hout, I., Galvin, I. F., Bunton, R. W., Davis, P., Williams, M. J. A., & Katare, R. (2019). Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium. Cardiovascular Diabetology, 18, 13. doi: 10.1186/s12933-019-0814-4

Fomison-Nurse, I., Saw, E. E. L., Gandhi, S., Munasinghe, P. E., Van Hout, I., Williams, M. J. A., Galvin, I., Bunton, R., Davis, P., Cameron, V., & Katare, R. (2018). Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells. Cell Death & Differentiation, 25, 1336-1349. doi: 10.1038/s41418-017-0047-6

Dixit, P., Donnelly, H., Edamatsu, M., Galvin, I., Bunton, R., & Katare, R. (2017). Progenitor cells from atria, ventricle and peripheral blood of the same patients exhibit functional differences associated with cardiac repair. International Journal of Cardiology, 228, 412-421. doi: 10.1016/j.ijcard.2016.11.178

Rawal, S., Munasinghe, E. P., Nagesh, P. T., Lew, J. K. S., Jones, G. T., Williams, M. J. A., Davis, P., Bunton, R. W., Galvin, I. F., Manning, P., Lamberts, R. R., & Katare, R. (2017). Downregulation of miR-15a/b accelerates fibrotic remodelling in the Type-2 diabetic human and mouse heart. Clinical Science, 131(9), 847-863. doi: 10.1042/cs20160916

Rawal, S., Munasinghe, P. E., Shindikar, A., Paulin, J., Cameron, V., Manning, P., Williams, M. J. A., Jones, G. T., Bunton, R., Galvin, I., & Katare, R. (2017). Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. Cardiovascular Research, 113(1), 90-101. doi: 10.1093/cvr/cvw235

Journal - Research Article

Rawal, S., Nagesh, P. T., Coffey, S., Van Hout, I., Galvin, I. F., Bunton, R. W., Davis, P., Williams, M. J. A., & Katare, R. (2019). Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium. Cardiovascular Diabetology, 18, 13. doi: 10.1186/s12933-019-0814-4

Fomison-Nurse, I., Saw, E. E. L., Gandhi, S., Munasinghe, P. E., Van Hout, I., Williams, M. J. A., Galvin, I., Bunton, R., Davis, P., Cameron, V., & Katare, R. (2018). Diabetes induces the activation of pro-ageing miR-34a in the heart, but has differential effects on cardiomyocytes and cardiac progenitor cells. Cell Death & Differentiation, 25, 1336-1349. doi: 10.1038/s41418-017-0047-6

Dixit, P., Donnelly, H., Edamatsu, M., Galvin, I., Bunton, R., & Katare, R. (2017). Progenitor cells from atria, ventricle and peripheral blood of the same patients exhibit functional differences associated with cardiac repair. International Journal of Cardiology, 228, 412-421. doi: 10.1016/j.ijcard.2016.11.178

Rawal, S., Munasinghe, P. E., Shindikar, A., Paulin, J., Cameron, V., Manning, P., Williams, M. J. A., Jones, G. T., Bunton, R., Galvin, I., & Katare, R. (2017). Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. Cardiovascular Research, 113(1), 90-101. doi: 10.1093/cvr/cvw235

Rawal, S., Munasinghe, E. P., Nagesh, P. T., Lew, J. K. S., Jones, G. T., Williams, M. J. A., Davis, P., Bunton, R. W., Galvin, I. F., Manning, P., Lamberts, R. R., & Katare, R. (2017). Downregulation of miR-15a/b accelerates fibrotic remodelling in the Type-2 diabetic human and mouse heart. Clinical Science, 131(9), 847-863. doi: 10.1042/cs20160916

Munasinghe, P. E., Riu, F., Dixit, P., Edamatsu, M., Saxena, P., Hamer, N. S. J., Galvin, I. F., Bunton, R. W., Lequeux, S., Jones, G., Lamberts, R. R., … Katare, R. (2016). Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway. International Journal of Cardiology, 202, 13-20. doi: 10.1016/j.ijcard.2015.08.111

Coffey, S., Williams, M. J. A., Phillips, L. V., Galvin, I. F., Bunton, R. W., & Jones, G. T. (2016). Integrated microRNA and messenger RNA analysis in aortic stenosis. Scientific Reports, 6, 36904. doi: 10.1038/srep36904

Rawal, S., Parshu Ram, T., Coffey, S., Williams, M. J. A., Saxena, P., Bunton, R. W., Galvin, I. F., & Katare, R. (2016). Differential expression pattern of cardiovascular microRNAs in the human type-2 diabetic heart with normal ejection fraction. International Journal of Cardiology, 202, 40-43. doi: 10.1016/j.ijcard.2015.08.161

Bussey, C. T., Hughes, G., Saxena, P., Galvin, I. F., Bunton, R. W., Noye, M. K., Coffey, S., Williams, M. J. A., Baldi, J. C., Jones, P. P., & Lamberts, R. R. (2015). Chamber-specific changes in calcium-handling proteins in the type 2 diabetic human heart with preserved ejection fraction. International Journal of Cardiology, 193, 53-55. doi: 10.1016/j.ijcard.2015.05.053

Munasinghe, P. E., Riu, F., Dixit, P., Edamatsu, M., Saxena, P., Hamer, N. S. J., Galvin, I. F., Bunton, R. W., Lequeux, S., Jones, G., Lamberts, R., … Katare, R. (2015). Data supporting the activation of autophagy genes in the diabetic heart. Data in Brief, 5, 269-275. doi: 10.1016/j.dib.2015.09.003

Moore, A., Shindikar, A., Fomison-Nurse, I., Riu, F., Munasinghe, P. E., Parshu Ram, T., Saxena, P., Coffey, S., Bunton, R. W., Galvin, I. F., Williams, M. J. A., … Katare, R. (2014). Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1. Cardiovascular Diabetology, 13, 68. doi: 10.1186/1475-2840-13-68

Lamberts, R. R., Lingam, S. J., Wang, H.-Y., Bollen, I. A. E., Hughes, G., Galvin, I. F., Bunton, R. W., Bahn, A., Katare, R., Baldi, J. C., Williams, M. J. A., Saxena, P., Coffey, S., & Jones, P. P. (2014). Impaired relaxation despite upregulated calcium-handling protein atrial myocardium from type 2 diabetic patients with preserved ejection fraction. Cardiovascular Diabetology, 13, 72. doi: 10.1186/1475-2840-13-72

Galvin, S. D., Celi, L. A., Thomas, K. N., Clendon, T. R., Galvin, I. F., Bunton, R. W., & Ainslie, P. N. (2010). Effects of age and coronary artery disease on cerebrovascular reactivity to carbon dioxide in humans. Anaesthesia & Intensive Care, 38(4), 710-717.

Jones, G. T., Solomon, C., Moaveni, A., van Rij, A. M., Thomson, I. A., & Galvin, I. (1999). Venous morphology predicts class of chronic venous insufficiency. European Journal of Vascular & Endovascular Surgery, 18(4), 349-354. doi: 10.1053/ejvs.1999.0902

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Journal - Research Other

Ram, T. P., Fomison-Nurse, I., Gandhi, S., Coffey, S., Saxena, P., Galvin, I., Bunton, R., Williams, M. J. A., Lamberts, R. R., & Katare, R. (2017). The diagnostic sensitivity of circulating cardio-enriched microRNAs is increased after normalization of high-density lipoprotein levels [Short communication]. International Journal of Cardiology, 236, 498-500. doi: 10.1016/j.ijcard.2017.01.119

Galvin, I. F., Haji Mohd Yasin, N. A. B., & Saxena, P. (2013). Kinky circumflex grafts: The left appendage flip maneuver. Thoracic & Cardiovascular Surgeon, 60(08), 687-690. doi: 10.1055/s-0033-1351117

Saxena, P., Chai, P. H.-Y., & Galvin, I. (2012). Composite venous coronary grafts: Construction made simple. Annals of Thoracic Surgery, 93(4), 1324-1325. doi: 10.1016/j.athoracsur.2011.11.069

Galvin, S. D., Wademan, B., & Galvin, I. F. (2012). Pulmonary embolism secondary to metastatic renal cell carcinoma. Journal of Cardiac Surgery, 27(6), 707-708. doi: 10.1111/j.1540-8191.2012.01427.x

Galvin, I. F., & Galvin, S. D. (2010). Top-end aortocoronary anastomosis made easy: The visor technique. Journal of Cardiac Surgery, 25(5), 511-512. doi: 10.1111/j.1540-8191.2010.01090.x

Galvin, S. D., Ninan, S. B., Lau, G. B., & Galvin, I. F. (2010). Rupture of aortic pseudoaneurysm arising from a transverse aortotomy line 12 years following mechanical aortic valve replacement [Case report]. Journal of Cardiac Surgery, 25(5), 563-565. doi: 10.1111/j.1540-8191.2010.01068.x

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