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Otago Medical School staff profiles

Mhairi Nimick

PositionAssistant Research Fellow
DepartmentDepartment of Pharmacology and Toxicology
Research summaryCancer drug development

Research

Mhairi works with Associate Professor Rhonda Rosengren.

Publications

Finlay, D. B., Sircombe, K. J., Nimick, M., Jones, C., & Glass, M. (2020). Terpenoids from cannabis do not mediate an entourage effect by acting at cannabinoid receptors. Frontiers in Pharmacology, 11, 359. doi: 10.3389/fphar.2020.00359

Bland, A. R., Bower, R. L., Nimick, M., Hawkins, B. C., Rosengren, R. J., & Ashton, J. C. (2019). Cytotoxicity of curcumin derivatives in ALK positive non-small cell lung cancer. European Journal of Pharmacology, 865, 172749. doi: 10.1016/j.ejphar.2019.172749

Shrestha, N., Lateef, Z., Martey, O., Bland, A. R., Nimick, M., Rosengren, R., & Ashton, J. C. (2019). Does the mouse tail vein injection method provide a good model of lung cancer? F1000Research, 8, 190. doi: 10.12688/f1000research.17964.1

Shrestha, N., Nimick, M., Dass, P., Rosengren, R. J., & Ashton, J. C. (2019). Mechanisms of suppression of cell growth by dual inhibition of ALK and MEK in ALK-positive non-small cell lung cancer. Scientific Reports, 9, 18842. doi: 10.1038/s41598-019-55376-4

Chen, S., Nimick, M., Cridge, A. G., Hawkins, B. C., & Rosengren, R. J. (2018). Anticancer potential of novel curcumin analogs towards castrate-resistant prostate cancer. International Journal of Oncology, 52(2), 579-588. doi: 10.3892/ijo.2017.4207

Journal - Research Article

Finlay, D. B., Sircombe, K. J., Nimick, M., Jones, C., & Glass, M. (2020). Terpenoids from cannabis do not mediate an entourage effect by acting at cannabinoid receptors. Frontiers in Pharmacology, 11, 359. doi: 10.3389/fphar.2020.00359

Bland, A. R., Bower, R. L., Nimick, M., Hawkins, B. C., Rosengren, R. J., & Ashton, J. C. (2019). Cytotoxicity of curcumin derivatives in ALK positive non-small cell lung cancer. European Journal of Pharmacology, 865, 172749. doi: 10.1016/j.ejphar.2019.172749

Shrestha, N., Nimick, M., Dass, P., Rosengren, R. J., & Ashton, J. C. (2019). Mechanisms of suppression of cell growth by dual inhibition of ALK and MEK in ALK-positive non-small cell lung cancer. Scientific Reports, 9, 18842. doi: 10.1038/s41598-019-55376-4

Shrestha, N., Lateef, Z., Martey, O., Bland, A. R., Nimick, M., Rosengren, R., & Ashton, J. C. (2019). Does the mouse tail vein injection method provide a good model of lung cancer? F1000Research, 8, 190. doi: 10.12688/f1000research.17964.1

Chen, S., Nimick, M., Cridge, A. G., Hawkins, B. C., & Rosengren, R. J. (2018). Anticancer potential of novel curcumin analogs towards castrate-resistant prostate cancer. International Journal of Oncology, 52(2), 579-588. doi: 10.3892/ijo.2017.4207

Martey, O., Nimick, M., Taurin, S., Sundararajan, V., Greish, K., & Rosengren, R. J. (2017). Styrene maleic acid-encapsulated RL71 micelles suppress tumor growth in a murine xenograft model of triple negative breast cancer. International Journal of Nanomedicine, 12, 7225-7237. doi: 10.2147/ijn.s148908

Wilson, C., Nimick, M., Nehoff, H., & Ashton, J. C. (2017). ALK and IGF-1R as independent targets in crizotinib resistant lung cancer. Scientific Reports, 7, 13955. doi: 10.1038/s41598-017-14289-w

Taurin, S., Nimick, M., Larsen, L., & Rosengren, R. J. (2016). A novel curcumin derivative increases the cytotoxicity of raloxifene in estrogen receptor-negative breast cancer cell lines. International Journal of Oncology, 48, 385-398. doi: 10.3892/ijo.2015.3252

De Wever, V., Nasa, I., Chamousset, D., Lloyd, D., Nimick, M., Trinkle-Mulcahy, L., … Moorhead, G. B. G. (2014). The human mitotic kinesin KIF18A binds protein phosphatase 1 (PP1) through a highly conserved docking motif. Biochemical & Biophysical Research Communications, 453(3), 432-437. doi: 10.1016/j.bbrc.2014.09.105

Skene-Arnold, T. D., Luu, H. A., Uhrig, R. G., De Wever, V., Nimick, M., Maynes, J., … Holmes, C. F. B. (2013). Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins. Biochemical Journal, 449(3), 649-659. doi: 10.1042/BJ20120506

De Wever, V., Lloyd, D. C., Nasa, I., Nimick, M., Trinkle-Mulcahy, L., Gourlay, R., … Moorhead, G. B. G. (2012). Isolation of human mitotic protein phosphatase complexes: Identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21. PLoS ONE, 7(6), e39510. doi: 10.1371/journal.pone.0039510

Tran, H. T., Nimick, M., Uhrig, R. G., Templeton, G., Morrice, N., Gourlay, R., … Moorhead, G. B. G. (2012). Arabidopsis thaliana histone deacetylase 14 (HDA14) is an α-tubulin deacetylase that associates with PP2A and enriches in the microtubule fraction with the putative histone acetyltransferase ELP3. Plant Journal, 71(2), 263-272. doi: 10.1111/j.1365-313X.2012.04984.x

Araújo, W. L., Tohge, T., Nunes-Nesi, A., Daloso, D. M., Nimick, M., Krahnert, I., … Fernie, A. R. (2012). Phosphonate analogs of 2-oxoglutarate perturb metabolism and gene expression in illuminated Arabidopsis leaves. Frontiers in Plant Science, 3, 114. doi: 10.3389/fpls.2012.00114

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Journal - Research Other

Tran, H. T., Uhrig, R. G., Nimick, M., & Moorhead, G. B. (2012). Interfacing protein lysine acetylation and protein phosphorylation: Ancient modifications meet on ancient proteins [Short communication]. Plant Signaling & Behavior, (7), 8, 901-903. doi: 10.4161/psb.20704

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