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The role of extracellular vesicles in immune regulation by cancer-causing human papillomaviruses

A postgraduate research opportunity at the University of Otago.

Details

Academic background
Sciences, Health Sciences
Host campus
Dunedin
Qualifications
Honours, Master’s, PhD
Departments
Pathology (Dunedin), Medicine (Dunedin)
Supervisor
Associate Professor Merilyn Hibma

Overview

High-risk human papillomavirus (HPV) types cause cancer of the cervix, and many head and neck cancers.  Our research explores viral regulation of the host immune response by HPV.  We are particularly interested in the role of extracellular vesicles (EVs) in the regulation of immunity by HPV.

EVs are particles that are naturally released from cells.  They can be taken up by other cells, and can alter their function.  The focus of the project is to explore the immune regulatory effects of EVs on cells of the immune system.

Understanding the immune regulatory effects of HPV is important for the design of immune therapies for cancer caused by this virus.

Contact

Merilyn Hibma
Email   merilyn.hima@otago.ac.nz