Predicting a positive response to physiotherapy treatments for patients in the MOA Trial

Principal Investigators: Cathy Chapple (PhD Candidate), Dr Alexis Wright (PhD Candidate)

Co-Investigators: Associate Professor J Haxby Abbott (Orthopaedic Surgery, Department of Surgical Sciences), Professor G David Baxter (School of Physiotherapy), Associate Professor John Dockerty (Department of Preventive & Social Medicine), Professor Helen Nicholson (Otago School of Medical Sciences)

Study Details

Objective: To determine clinical prognostic factors that maximize the accuracy of identifying patients with hip or knee osteoarthritis likely to demonstrate a favorable response to physiotherapy treatment.

Design: Prognostic studies nested within the MOA Trial RCT.

Methods: Participants in the MOA Trial were assessed at baseline in order to later determine which patient characteristics, when clustered together, were most predictive of a favorable response to physical therapy treatment. Positive responders to the MOA Trial physiotherapy interventions were identified after one year.

Conclusions: Both the hip study (Dr Lexie Wright) and the knee study (Cathy Chapple) found clustered combinations of clinical findings that indicate the probability of a favorable response to physiotherapy treatment in patients with OA.


HRCThis research was funded by the Health Research Council of New Zealand.



Wright AA, Cook CE, Flynn TW, Baxter GD, Abbott JH. Predictors for response to therapeutic physical therapy interventions in patients with primary hip osteoarthritis. Physical Therapy. 2011; 91(4):510-524. doi: 10.2522/ptj.20100171


Department of Surgical Sciences Orthopaedic Surgery University of Otago Dunedin School of Medicine