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Principal Investigator

Christine Jasoni 186x228Professor Christine Jasoni

Email christine.jasoni@otago.ac.nz
Tel +64 3 479 3071
Fax +64 3 479 7254
Laboratory of Developmental Neuroendocrinology
Department of Anatomy website

Research interests

The focus of our research is on discovering how the maternal environment during pregnancy affects the formation of the fetal brain. With conditions such as obesity and diabetes on the rise in Western society, it is critical that we fully understand the health implications of these disorders for future generations.

At the Centre for Neuroendocrinology we seek to:

  • Discover epigenetic changes in the brains of the offspring of obese or diabetic mothers
  • Establish specifically how these changes bring about altered development of axon tracts in the offspring hypothalamus

Clinical conditions

Jasoni Laboratory staff & students

Yugo Watanabe_webYugo Watanabe, Postdoctoral Fellow
The origins of PCOS by prenatal androgen exposure
Email yugo.watanabe@otago.ac.nz

Visit Our people for an alphabetical list of all Centre for Neuroendocrinology staff.

Research Funders

Publications

Higgins, M. B. A., Glendining, K. A., & Jasoni, C. L. (2024). The temporal and spatial pattern of leptin receptor-expressing cells in the developing mouse hypothalamus. Journal of Neuroendocrinology, 36, e13366. doi: 10.1111/jne.13366

Richard, S., Zhou, Y., Jasoni, C. L., & Pankhurst, M. W. (2024). Ovarian follicle size or growth rate can both be determinants of ovulatory follicle selection in mice. Biology of Reproduction, 110(1), 127-136. doi: 10.1093/biolre/ioad134

Prescott, M., Watanabe, Y., Ruddenklau, A., Fisher, L., Jasoni, C. L., & Campbell, R. E. (2023). Kisspeptin neuron projections and expression patterns are unaltered in prenatally androgenized female mice modeling PCOS. Journal of the Endocrine Society, 7(Suppl. 1), (pp. A649-A650). doi: 10.1210/jendso/bvad114.1213

Kamstra, K., van der Burg, C., Quertermous, H. M., Muncaster, S., Todd, E. V., Jasoni, C. L., … Gemmell, N. J. (2023). Neuroanatomy of a sex changing fish: The New Zealand spotty wrasse (Notolabrus celidotus) brain atlas. New Zealand Journal of Zoology. Advance online publication. doi: 10.1080/03014223.2023.2216939

Watanabe, Y., Fisher, L., Campbell, R. E., & Jasoni, C. L. (2023). Defining potential targets of prenatal androgen excess: Expression analysis of androgen receptor on hypothalamic neurons in the fetal female mouse brain. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13302

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