Novel Mutations as a Driver of Daptomycin Resistance in VRE.
Adrianna Turner PhD candidate, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Australia.
Bacterial pathogens such as vancomycin-resistant Enterococcus faecium (VRE) that resist all antibiotics are among the top threats to human health.
Utilising a combination of phylogenetics and molecular microbiology approaches, we identified novel mutations associated with daptomycin resistance in VRE, with globally circulating lineages harbouring these mutations. Importantly, we uncover the therapeutic use of an unrelated, prophylactic antibiotic has likely led to the international dissemination of daptomycin-resistant strains harbouring these novel mutations of resistance.
Zoom link: https://otago.zoom.us/j/98929322137
|Date||Monday, 15 August 2022|
|Time||1:00pm - 2:00pm|
|Event Category||Health Sciences|
|Department||Microbiology and Immunology|
|Contact Name||Jennifer van Eunen|
|Contact Phone||+64 3 479 7734|