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Novel mutations as a driver of dapromycin resistance in VRE

Novel Mutations as a Driver of Daptomycin Resistance in VRE.

Adrianna Turner PhD candidate, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Australia.

Bacterial pathogens such as vancomycin-resistant Enterococcus faecium (VRE) that resist all antibiotics are among the top threats to human health.

Utilising a combination of phylogenetics and molecular microbiology approaches, we identified novel mutations associated with daptomycin resistance in VRE, with globally circulating lineages harbouring these mutations. Importantly, we uncover the therapeutic use of an unrelated, prophylactic antibiotic has likely led to the international dissemination of daptomycin-resistant strains harbouring these novel mutations of resistance.

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Date Monday, 15 August 2022
Time 1:00pm - 2:00pm
Audience Postgraduate students,Staff
Event Category Health Sciences
Event Type Seminar
DepartmentMicrobiology and Immunology
LocationVia Zoom
Contact NameJennifer van Eunen
Contact Phone+64 3 479 7734

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