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Investigating the relationship between microRNA expression, brain structure and biochemistry in anxiety disorders and their potential treatment with ketamine

This seminar will outline the background and methodology in Sophie's upcoming PhD, as well as some preliminary results from her first year.

Sophie will start with a brief background on anxiety disorders, including how discerning underlying pathologies are vital to producing better treatment outcomes. She will then explore how neuroimaging (structural and chemical brain quantification using Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy) and differential gene expression (microRNA) have contributed to a better understanding of anxiety pathology.

Following this background, Sophie will share the rationale and some preliminary results from the first aspect of her PhD; investigating correlates between brain structure and anxiety/depression symptoms in an amalgamated cohort of healthy participants.

In the final part of the seminar, Sophie will introduce the future directions of her PhD, investigating correlates between brain structure, chemistry, and gene expression in a cohort of people with treatment-resistant anxiety disorders, and their response to a pharmacotherapy trial with Ketamine.

Date Monday, 12 September 2022
Time 12:00pm - 1:00pm
Audience Public,Undergraduate students,Postgraduate students,Staff
Event Category Sciences
Event Type Seminar
LocationGoddard Laboratories, Room 2.02, Dunedin
Contact NameNarun Pat

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