Fertility in all mammals is regulated by neuronal circuits in the hypothalamus, which converge onto the gonadotropin-releasing hormone (GnRH) neurons. These circuits integrate internal and external cues to generate appropriate patterns of GnRH secretion. In females, the central circadian clock precisely times the preovulatory GnRH surge, ensuring that ovulation coincides with sex behaviour. Our research combines anatomical and functional approaches to understand how neurons in the suprachiasmatic nucleus – which hosts the central clock – may drive the activity of GnRH neurons and their afferent circuits to accurately time the preovulatory surge.
|Date||Monday, 19 November 2018|
|Time||1:00pm - 2:00pm|
|Event Category||Health Sciences|
|Location||Hercus d'Ath Lecture Theatre, Great King Street|