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Regulation of the neuronal circuits that control fertility by the central circadian clock

Fertility in all mammals is regulated by neuronal circuits in the hypothalamus, which converge onto the gonadotropin-releasing hormone (GnRH) neurons. These circuits integrate internal and external cues to generate appropriate patterns of GnRH secretion. In females, the central circadian clock precisely times the preovulatory GnRH surge, ensuring that ovulation coincides with sex behaviour. Our research combines anatomical and functional approaches to understand how neurons in the suprachiasmatic nucleus – which hosts the central clock – may drive the activity of GnRH neurons and their afferent circuits to accurately time the preovulatory surge.

Date Monday, 19 November 2018
Time 1:00pm - 2:00pm
Audience All University
Event Category Health Sciences
Event Type Departmental Seminar
LocationHercus d'Ath Lecture Theatre, Great King Street

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