The incidence of Chlamydia infection, in both females and males, is increasing world-wide. Male infections have been associated clinically with urethritis, epididymitis and orchitis, believed to be caused by ascending infection, although the impact of infection on male fertility remains controversial. Using a mouse model of male chlamydial infection, we have demonstrated long lasting chronic infection in the testes resulting in germ cell DNA damage, impaired spermatogenesis, autoimmune disease, intergenerational effects on offspring and a haematogenous route of infection. Concomitant studies in human male infertility patients has revealed a hitherto unexpectedly high incidence of active chlamydial infection in asymptomatic men undergoing testicular biopsy for fertility assessment and assisted reproduction treatments.
|Date||Friday, 25 October 2019|
|Time||1:00pm - 2:00pm|
|Event Category||Health Sciences|
|Location||D'ath Lecture Theatre, Hercus Building|
|Contact Name||Dr Euan Rodger|