Associate Professor Rakesh Veedu
Center for Molecular Medicine and Innovative Therapeutics, Murdoch University, and Perron Institute for Neurological and Translational Science, Perth, Australia
Precision Nucleic Acids: Beginning of an Era of Gene-Targeting Therapies
Human genome sequencing has been a major milestone which significantly contributed towards the development of precision nucleic acid therapeutics to correct or regulate the expression of disease-causing genetic hallmarks. Various nucleic acid therapeutics approaches with different mechanisms of action including antisense oligonucleotides (ASOs), siRNAs, microRNA mimics, antimiRs, DNAzymes, aptamers and triplex-forming oligonucleotides have been developed over the years. Of these, ASO technology remains the most prominent and successful therapeutic strategy with eight ASO-based drugs approved for clinical use so far. Our research is focused on developing novel precision nucleic acid therapeutics and covers three core areas: nucleic acid synthesis, therapeutic & diagnostic development and nucleic acid drug delivery. My talk will provide an overview about our recent activities and the impact of oligonucleotide therapeutics for patient benefits.
A/Prof Veedu was an invited speaker at the recent Nucleic Acid Chemical Biology workshop at Massey University, and his visit to Dunedin is supported by the Departments of Pathology & Biochemistry.
|Date||Wednesday, 11 March 2020|
|Time||12:00pm - 1:00pm|
|Event Category||Health Sciences|
|Department||Biochemistry, Pathology (Dunedin)|
|Location||D’Ath Lecture Theatre, Department of Pathology|