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Department of Medicine Seminar Series

Is the healthy respiratory system built just right, overbuilt, or underbuilt to meet the demands imposed by exercise?

Emeritus Professor Jerome Dempsey PhD
International presenter via Zoom from UW-Madison School of Medicine and Public Health

In the healthy, untrained young adult, a case is made for a respiratory system (airways, pulmonary vasculature, lung parenchyma, respiratory muscles, and neural ventilatory control system) that is near ideally designed to ensure a highly efficient, homeostatic response to exercise of varying intensities and durations.

Our aim was then to consider circumstances in which the intra/extrathoracic airways, pulmonary vasculature, respiratory muscles, and/or blood-gas distribution are underbuilt or inadequately regulated relative to the demands imposed by the cardiovascular system.

In these instances, the respiratory system presents a significant limitation to O2 transport and contributes to the occurrence of locomotor muscle fatigue, inhibition of central locomotor output, and exercise performance.

Most prominent in these examples of an “underbuilt” respiratory system are highly trained endurance athletes, with additional influences of sex, aging, hypoxic environments, and the highly inbred equine.

We summarize by evaluating the relative influences of these respiratory system limitations on exercise performance and their impact on pathophysiology and provide recommendations for future investigation.

Date Friday, 12 February 2021
Time 1:00pm - 2:00pm
Audience All University,Other
Event Category Health Sciences
DepartmentMedicine (Dunedin)
Location9th floor Seminar Room, Dunedin Public Hospital, and via Zoom
Contact NameAmanda Buchanan

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