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Biochemistry Seminar: Associate Professor Liz Ledgerwood

Redox Signalling, Oxidative Stress and Ageing

Reactive oxygen species have both beneficial and detrimental effects in cells – on the one hand they can damage biomolecules but on the other they are essential signalling intermediates. Cells have a network of antioxidants that determine the cellular response to ROS, ranging from immediate protection to longer term adaptive responses. Variability in these responses is thought to contribute to a wide range of diseases and to normal ageing.

Our work is focused on understanding the redox networks and the role of these networks in various cellular contexts. Here I will present our data on these networks, and how we are analysing the relationship between redox networks and oxidative stress in participants in the Dunedin Multidisciplinary Health and Development Study, with a long term goal of understanding the role of redox networks and oxidative stress in ageing.

Date Tuesday, 20 April 2021
Time 12:00pm - 1:00pm
Audience All University
Event Category Health Sciences
Event Type Departmental Seminar
CampusDunedin
DepartmentBiochemistry
LocationBiochemistry Seminar Room BIG13, Dunedin
CostFree
Contact NameDepartment of Biochemistry
Contact Emailbiochemistry@otago.ac.nz

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