Previous winners of Otago Medical School Research Society prizes

1. Dr Indranil Basak
Department of Biochemistry
Characterisation of CLN5 Batten disease in induced pluripotent stem
cell derived human neurons.

Pat Cragg Summer Student Prize

1. Oscar German
Department of Biochemistry
Investigation of the mechanism of aspirin action in combined breast
cancer therapy.

2= Helene Chua
Department of Oral Rehabilitation
The cooling efficiency of different dental high-speed handpiece coolant
port designs.

2= Eleni Hackwell
Department of Anatomy
Prolactin action on kisspeptin neurons is required for maintaining
lactational infertility.

1= Adam Chau
Department of Pharmacology and Toxicology
Attenuation of ischaemia reperfusion injury in hypertrophic hearts with
oCOm-21: a potential inotrope through the modulation of calcium.
1= Grace Macaulay
Department of Women's and Children's Health
Sleep in children and adolescents with Type 1 Diabetes Mellitus.

1. Brin Ryder
   Department of Microbiology and Immunology
   Immunisation with BCG alters lung phagocyte dynamics during early mycobacterial infection of mice.
2. Serada Ketharnathan
   Department of Pathology
   A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression.

1. Sarah Donald
   Department of Preventive and Social Medicine
   Treating for two - exploring the use and safety of medicines in pregnancy.
2. Sarah Rhodes
   School of Physiotherapy
   Physical activity in obstructive sleep apnoea:If it were easy, everybody would be doing it.
3. Jessica Young
   Department of General Practice and Rural Health
   Is there a right time to die?

1. Rachel Darnell
   Department of Microbiology and Immunology
   Staying one step ahead: Understanding the development of resistance to new antimicrobial teixobactin using Enterococcus faecali as a model.

Pat Cragg Summer Student Prize

1. Sophie Mathiesen
   Department of Psychology and Department of Biochemistry
   Assessing the efficacy of a novel adeno-associated viral capsid in targeting the brain.
2. Ashton Blake-Barlow
   Departments of Medicine and Department of Surgical Sciences
   Aortic size index to predict risk in coronary artery disease patients.

1. Maya Wilde
   Department of Psychology
   Secreted amyloid precursor protein-alpha and active peptide fragments regulate neuronal morphology.
2. Sarah Trevelyan
   Department of Biochemistry
   Characterisation of C-terminal oligomerisation domains within Apoptosis Signal-regulating Kinases.

1. Roisin Hegarty
   Department of Psychology
   Accepting the things we cannot change – a solution to the problem of fatigue in arthritis?
2. Alice-Roza Eruera
   Department of Microbiology and Immunology
   Parasites and People; a Malarious Relationship.
3. Sarah Parackal
   Department of Biochemistry
   Blood Will Tell! Circulating Tumour DNA as a Diagnostic and Surveillance Clinical Tool for Cancer Patients.

1. Hannah Best
   Department of Biochemistry
   Therapeutic targeting of cellular clearance pathways in neurodegenerative Batten disease.

1. Stella Cameron
   Department of Anatomy
   Pathophysiological and anatomical changes of the deep cerebellar nuclei in a chronic rat model of Parkinson's disease.
2. Matthew Sykes
   Department of Anatomy
   Low-intensity magnetic stimulation and excitability in the rodent neocortex as measured by local field potentials

1. Carol Bussey
   Department of Physiology
   Increased right cardiac sympathetic and parasympathetic nerve activity in type 2 diabetes.

Pat Cragg Summer Student Prize

1. Julia Gouws
   Department of Physiology
   Determining sexually dimorphic changes in CRH neural network activity induced by stress hormones.

2= Bryony Hamilton
Department of Pathology
A new peripheral blood test for HPV to predict perinatal disease.
2= Jodi Thomas
Department of Anatomy
Investigating early genetic regulators of sex change in labrid fish.

1. Natalie Fleming
   School of Pharmacy
   A mathematical model for urate transport across a proximal tubule cell.
   
2. Bradley Jamieson
   Centre for Neuroendocrinology and the Department of Physiology
   Endocannabinoid-mediated negative feedback control of the stress axis.
   

1. Hannah Kennedy
   A Diagnostic Odyssey: Finding a Cardiac Killer
   
2. Sarah Maessen
   The perils of snoring: Don't ignore the elephant in the bedroom

1. Kirsten Ward
   Department of Microbiology and Immunology
   Effector regulatory T cells are associated with disease-free survival in colorectal cancer.
2. Safina Gadeock
   Department of Physiology
   Increased permeability is an inherent defect in the colonic epithelium of Chrohn's disease patients.

1. Sujita Narayan
   School of Pharmacy
   Antihypertensive medicines utilisation: A decade-long nationwide study of octogenarians, nonagenarians and centenarians.

Research Staff 234^th Meeting

1. Dr Emmet Power
   Department of Physiology
   Altered metabotropic glutamate receptor activity in early spinocerebellar ataxia type 1.

Summer Students
233^rd Meeting

Pat Cragg Summer Student Prize

1. Danyon Graham
   Sir John Walsh Research Institute, Faculty of Dentistry
   The molecular basis of triazole inhibition of an antifungal target.
2. Isabelle van Hout
   Department of Physiology
   The effects of bacterial components on colonic stem cell proliferation.
   

1. Christopher Hakkaart and Parry Guilford
   Department of Biochemistry
   Screening for predisposition for gastric cancer in Māori

Honours/Masters
232^nd Meeting

1. Olivia Egan
   Department of Anatomy
   Leptin receptor signalling in Agouti-related peptide (AgRP) neurons modulates puberty
2. Sarah Scott
   School of Physiotherapy
   "Not always a straight path": patients' perspectives following anterior cruciate ligament rupture and reconstruction.

PhD 231^st Meeting

1. Andrew Reynolds,
   Department of Human NutritionImpact of glycaemia of walking after eating and standard physical activity advice in type 2 diabetes: a randomised crossover trial
   
2. Kate Thomas,
   School of Physical Education, Sport and Exercise Sciences
   Hot-water immersion increases popliteal artery shear stress in peripheral arterial disease

1. Nikita Potemkin,
   Department of Anatomy
   Helping the fights against Alzheimer's disease: beating the bullies
2. Aimee Ward,
   Department of Preventive and Social Medicine and Department of Geography
   How do we know the 'Happy Wanderer' is really happy?

1. Dr Owen Jones
   Department of Psychology and Brain Health Research Centre
   Astrocytes regulate synaptic plasticity in the hippocampus.
   

Summer Students
228^th Meeting

Pat Cragg Summer Student Prize

1. Philippa Ross,
   Department of Women's and Children's Health
   Incidence and characteristics of insulin pump-associated adverse events in New Zealand children and adults with type 1 diabetes mellitus
2. Terry Zhang
   Department of Anatomy
   Evaluating the immune modulating effects of microparticles from Human papillomavirus type 16-E7 expressing keratinocytes on Langerhans cell-like cells

1. Tim Hodgson
   Southern District Health Board
   Green inclusions seen in neutrophils and monocytes are lipid-rich and associated with ischaemic hepatitis, lactic acidosis and high mortality
2. Harry Dean
   Department of General Surgery
   Improving trauma team function at Dunedin Public Hospital

Pre-Doctoral meeting
226th meeting

1. Kieran Bunn
   Department of Women's and Children's Health
   Novel mutations in DVL1 cause an increase in bone mineral density through the WNT signalling pathway
2. Samuel Wilkins
   Department of Microbiology and Immunology
   Engineering electrospun nanofibres with orf virus proteins for improved wound healing

1. Sam Norton
   Department of Microbiology and Immunology
   Colorectal tumour associated macrophages are more pro-inflammatory than adjacent control bowel tissue macrophage populations
   
2. Nicole Neverman
   Department of Biochemistry
   Identification and correction of prenatal synaptic pathologies in CLN6 ovine Batten disease.

1. Joanne Jung Eun Choi
   Sir John Walsh Research Institute, Faculty of Dentistry
   Continuous and simultaneous measurement of intraoral pH and temperature

1. Chris Harris
   Masters student, Department of Biochemistry
   Unlocking Prostate Cancer
2. Monika Sharma
   PhD student, Department of Biochemistry
   Lipoprotein(a): step-child in the lipid family

1. Su Young Han
   Department of Physiology
   Optogenetic control of arcuate kisspeptin neurons in vivo

1. Ivor Malahay (1st=)
   Department of Physiology
   COMMD10 is important for zymogen granule formation in AR42J pancreatic acinar cells
   Chris Marshall (1st=)
   Department of Physiology
   Measuring pulsatile lutenizing hormone secretion in a prenatal androgen treated model of polycystic ovarian syndrome

1. Tracey Putt
   Department of Medicine
   GFR may not accurately predict aspects of proximal tubule drug handling

Science Writing Prize

1. Sophia Cameron-Christie
   PhD Student, Department of Women's and Children's Health
2. Brigid Ryan
   PhD Student, Department of Anatomy

Pre-Doctoral
220th Meeting

1. Crystal Diong
   Department of Physiology
   Increased sympathetic activity in obesity may protect against pulmonary hypertension
2. Hannah Twigg
   Centre for Neuroendocrinology and Department of Anatomy
   The effect of maternal obesity of developmental gene expression in the fetal arcuate nucleus

PhD Students
219th Meeting

1. Simon de Croft
   Centre for Neuroendocrinology and Department of Physiology
   Peptidergic intercommunication between kisspeptin neurons of the arcuate nucleus of the male mouse
2. Maggie Corr
   Centre for Neuroendocrinology and Department of Anatomy
   Insulin receptor signalling in gamma-aminobutyric acid (GABA) neurons plays a role in regulating metabolic function, but not reproductive function, in female mice

Research Staff
217th Meeting

1. Clementine Bosch
   Department of Anatomy
   The role of the motor thalamus in Parkinson's disease

Summer Students
216th Meeting

1. Jessica Macindoe
   Department of Pharmacology and Toxicology
   In vitro preconditioning of hippocampal slices with GYKI-52466
2. Elliot Dunn
   Departments of Physiology, Microbiology and Immunology, and Medicine
   Long-term in vitro expansion of human intestinal organoids

Pre-Doctoral
215th Meeting

1. Papillon Gustafson
   Department of Anatomy
   Characterisation of a tamoxifen-inducible STAT5 knockout mouse
2. Elliot Dunn
   Department of Microbiology and Immunology
   Macrophage and T cell distribution in autoimmune inflammation of the gut

PhD Students
214th Meeting

1. Su Young Han
   Centre for Neuroendocrinology and Department of Physiology
   Induction of hypertension blunts baroreflex inhibition of vasopressin neuron activity in Cyp1a1-Ren2 (inducible hypertensive) rats
2. Ali Mirjalili
   Department of Anatomy
   Is iatrogenic injury of the spinal accessory nerve necessarily the surgeon's fault?

Post-Doctoral
212th Meeting

1. Jenny Clarkson
   Centre for Neuroendocrinology and Department of Physiology
   Gonadotrophin-releasing hormone and G-protein-coupled receptor-54 signaling are required to establish the sexually dimorphic brain of mice

Summer Students
211th Meeting

1. Daniel Sundaresan
   Faculty of Dentistry
   Investigating the oral bacterial diversity of Dunedin children
2. Samantha Murray
   Department of Anatomy
   Do schizophrenia-inducing signals alter development of the fetal brain?

1. Andrew Highton
   Department of Microbiology and Immunology
   Immunisation Using Sustained Release Vaccines Generates a Discrete CD8 T Cell Memory Population in the Gut

Pre-Doctoral
210th Meeting

1. Mike Fleete
   Department of Anatomy
   Altered nitric oxide synthase and arginase activity and expression in the Alzheimer's diseased brain
2. Yeri Kim
   Department of Physiology
   Alpha-7 nicotinic acetylcholine receptors contribute to cerebellar excitatory synaptic transmission

PhD Students
209th Meeting

1. Amy Wolf
   Department of Psychology
   Long-term consequences of maternal immune activation on contextual processing in the offspring: relevance to schizophrenia
2. Zarina D'Costa (2nd=)
   Microbiology and Immunology
   Human papillomavirus type 16 E6 regulates E-cadherin in a DNA methyltransferase-dependent manner
   Yanfeng Zhang (2nd=)
   Department of Anatomy and Structural Biology, Department of Psychology, and Brain Health Research Centre
   Timing dependent effects of reinforcement on visual responses in the superior colliculus

Post-Doctoral
208th Meeting

1. Karl Iremonger
   Centre for Neuroendocrinology and Department of Physiology
   An unusual site of action potential initiation in gonadotropin-releasing hormone (GnRH) neurons

Summer Students
207th Meeting

1. Clare Burn
   Department of Microbiology and Immunology
   Human papillomavirus virus-like particles and their potential as gene delivery vectors in the skin
2. Michael Fleete (2nd=)
   Department of Anatomy and Structural Biology
   Effects of aging on arginine metabolism in the striatum and spinal cord in rats
   Edward Ottley (2nd=)
   Anatomy and Structural Biology
   Activin C: a possible therapeutic target in prostate cancer progression

Pre-Doctoral
205th meeting

1. Dharshini Sreenivasan
   Department of Anatomy and Structural Biology
2. Shane Hellyer
   Department of Pharmacology and Toxicology

PhD Students
203rd Meeting

1. Jean-Ha Baek
   Department of Pharmacology and Toxicology
2. Evan Tan
   Department of Women's and Children's Health

Summer Students
202nd Meeting

1. John Zhang
   Department of Anatomy and Structural Biology
2. Jordan Vincent
   Department of Medical and Surgical Sciences

Post-Doctoral
201st Meeting

1. Dr Kristin Hillman
   Department of Psychology

1. Yie Kuan Wong
   Department of Microbiology and Immunology
2. Andrew Wong
   Department of Oral Sciences

1. Zsombor Koszegi
   Department of Physiology
2. Verity Oliver (2nd=)
   Department of Biochemistry
   Margriet van Kogelenberg (2nd=)
   Department of Paediatrics and Child Health

1. Kirstie Allen
   Department of Pharmacology and Toxicology
2. Michael Corbett
   Department of Microbiology and Immunology

1. Kajsa Igelstrom
2. Marcus Lee

1. Ian Winburn
2. Zabeen Lateef
3. Kelly McKelvey

1. Lisa Smith
2. Sara McKee

1. Shilpa Raju
   Department of Oral Sciences
2. Chamil Samaranayaka
   Department of Oral Sciences

1. Stephanie Sonnberg
   Department of Microbiology and Immunology
2. Dana Westphal
   Department of Microbiology and Immunology

1. Madihah Rushaidhi
   Department of Anatomy and Structural Biology
2. Zarina D'Costa
   Department of Microbiology and Immunology

1. Jenny Clarkson
   Department of Microbiology and Immunology
2. Francesca Crowel
   Department of Human Nutrition

1. Caroline Talbot
   Department of Anatomy and Structural Biology
2. Melissa Barry
   Department of Anatomy and Structural Biology