Research in our lab is carried out as part of the Sir John Walsh Research Institute. Our staff and students are part of the Oral Molecular and Immunopathology Research Group with a focus on molecular pathogenesis of oral diseases, with a particular emphasis on oral cancer and immune-mediated diseases.
Current projects
- Angiogenic factors in oral squamous cell carcinoma
- Angiogenic factors in the pulp-dentine complex
- Endoplasmic reticulum (ER) stress in the development of oral squamous cell carcinoma
- ER stress modulation of STAT3 pathways in oral squamous cell carcinoma
- Lymphangiogenesis in the oral squamous cell carcinoma microenvironment
- Novel cytokine networks in the pathogenesis of oral lichen planus
- Role of interleukin 17 (IL17) in the development of oral squamous cell carcinoma
- Stem cells derived from the dental pulp
- The role of angiogenesis in the pathogenesis of oral lichen planus
- The use of periosteum-derived mesenchymal multipotent progenitor cells for bone regeneration on titanium surfaces
- Exosomes in oral cancer
Research techniques
At the Oral Pathology Centre we have diagnostic level research equipment available for research use. All our equipmentare thoroughly maintained as per IANZ standardsand operated by registered medical laboratory scientists.
- Histology: Sample preparation, processing, embedding and blocking. Preparation of sections and routine / special staining.
- Frozen sections and cryostat
- Immunohistochemistry: Automated IHC immunostainer (Leica BOND-III). Diagnostic and research antibodies
- Immunofluorescence: Diagnostic quality Olympus LED immunofluorescence microscope.
- Digital whole slide scanning: Leica Aperio CS2and Olympus DP23. Whole slide scanning, diagnostic quality photomicrography
Further information
For more information and research opportunities, contact:
Dr Benedict Seo
Head, Oral Pathology Centre
Email benedict.seo@otago.ac.nz