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PHAL421 General Pharmacology and Toxicology

PHAL 421 consists of a series of lectures and is a requirement for both BSc(Hons) and MSc.

Paper title General Pharmacology and Toxicology
Paper code PHAL421
Subject Pharmacology
EFTS 0.1667
Points 20 points
Teaching period First Semester
Domestic Tuition Fees (NZD) $1,622.82
International Tuition Fees (NZD) $6,017.70

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Contact
paul.smith@otago.ac.nz
Teaching staff
Professor Rhonda Rosengren
Professor Paul Smith
Dr Lyn Wise
Textbooks

Textbooks are not required for this paper.

Graduate Attributes Emphasised
Interdisciplinary perspective, Lifelong learning, Scholarship, Communication, Critical thinking, Ethics, Environmental literacy, Research, Self-motivation, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
The aim of this paper is to provide an advanced general course in pharmacology and toxicology, with emphasis on issues relating to preclinical experimental research and the problems of translating this to clinical medicine. Statistical analysis of pharmacological data is also a core component of this paper.

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Course Coordinator

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Teaching staff 

Description

The PHAL 421 consists of a series of presentations and is a requirement for both BSc(Hons) and MSc.  

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Course objectives

The aim of this paper is to provide an advanced general course in pharmacology and toxicology, with emphasis on issues relating to preclinical experimental research and the problems of translating this to clinical medicine. The PHAL 421 course will consist of a series of presentations and will run for two hours per week, on Tuesdays from 9am–11 am. 

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Course content

Part 1: Translational Pharmacology

  • Reproducibility of results in the biomedical literature
  • Quality of experimental design in biomedical science I
  • Quality of experimental design in biomedical science II
  • Translating preclinical research to clinical medicine
  • Animal models in preclinical research

Part 2: Advanced Pharmacodynamics and Pharmacokinetics

  • Advanced PK. Drug Metabolism I
  • Advanced PK. Drug Metabolism II
  • Advanced PK. Drug Formulation
  • Advanced PD. Dose response and drug combination
  • Advanced PD. Personalised medicine
  • Dr Sarah Baird's topic
  • Review Section
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Assessment

  • Assignment 1 (20%)
    • Students will a series of related research articles from a list of options provided and critically review the experimental design followed in the investigations. Limit is 3000 words.
  • Essay (20%)
    • Students are required to write a 3000 word essays reviewing the strengths and weaknesses of ONE preclinical model as a paradigm for studying a human pathology.
  • Final exam (60%)

For more information on this course, please contact Professor Paul Smith:

Email paul.smith@otago.ac.nz

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Timetable

First Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
A1 Tuesday 09:00-10:50 9-16, 18-22