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Pharmacy staff profile

Isabelle Kuan

PositionPhD Student
Research summaryModel-based estimation of glomerular filtration rate

Additional details

Supervised by Dr Dan Wright and Professor Steve Duffull, and sponsored by NZPERF.

Publications

Pradhan, S., Duffull, S. B., Wilson, L. C., Kuan, I. H. S., Walker, R. J., Putt, T. L., Schollum, J. B. W., & Wright, D. F. B. (2021). Does the intact nephron hypothesis provide a reasonable model for metformin dosing in chronic kidney disease? British Journal of Clinical Pharmacology. Advance online publication. doi: 10.1111/bcp.14919

Kuan, I. H. S., Wilson, L. C., Leishman, J. C., Cosgrove, S., Walker, R. J., Putt, T. L., Schollum, J. B. W., & Wright, D. F. B. (2021). Metformin doses to ensure efficacy and safety in patients with reduced kidney function. PLoS ONE, 16(2), e0246247. doi: 10.1371/journal.pone.0246247

Kuan, I. H. S., Wright, D. F. B., Duffull, S. B., & Zhu, X. (2020). Understanding the association between metformin plasma concentrations and lactate. British Journal of Clinical Pharmacology, 87(2), 700-701. doi: 10.1111/bcp.14394

Sinnappah, K. A., Kuan, I. H. S., Thynne, T. R. J., Doogue, M. P., & Wright, D. F. B. (2020). The pharmacokinetics of metformin in patients receiving intermittent haemodialysis [Short report]. British Journal of Clinical Pharmacology, 86, 1430-1443. doi: 10.1111/bcp.14244

Ji, X.-W., Xue, F., Kang, Z.-S., Zhong, W., Kuan, I. H.-s., Yang, X.-P., Zhu, X., … Lv, Y. (2020). Model-informed drug development, pharmacokinetic/pharmacodynamic cutoff value determination, and antibacterial efficacy of benapenem against Enterobacteriaceae. Antimicrobial Agents & Chemotherapy, 64(3), e01751-19. doi: 10.1128/aac.01751-19

Kuan, I. H. S., Wilson, L. C., Leishman, J. C., Cosgrove, S., Walker, R. J., Putt, T. L., Schollum, J. B. W., & Wright, D. F. B. (2021). Metformin doses to ensure efficacy and safety in patients with reduced kidney function. PLoS ONE, 16(2), e0246247. doi: 10.1371/journal.pone.0246247

Journal - Research Article

Pradhan, S., Duffull, S. B., Wilson, L. C., Kuan, I. H. S., Walker, R. J., Putt, T. L., Schollum, J. B. W., & Wright, D. F. B. (2021). Does the intact nephron hypothesis provide a reasonable model for metformin dosing in chronic kidney disease? British Journal of Clinical Pharmacology. Advance online publication. doi: 10.1111/bcp.14919

Journal - Research Article

Ji, X.-W., Xue, F., Kang, Z.-S., Zhong, W., Kuan, I. H.-s., Yang, X.-P., Zhu, X., … Lv, Y. (2020). Model-informed drug development, pharmacokinetic/pharmacodynamic cutoff value determination, and antibacterial efficacy of benapenem against Enterobacteriaceae. Antimicrobial Agents & Chemotherapy, 64(3), e01751-19. doi: 10.1128/aac.01751-19

Journal - Research Article

Kuan, I. H. S., Savage, R. L., Duffull, S. B., Walker, R. J., & Wright, D. F. B. (2019). The association between metformin therapy and lactic acidosis. Drug Safety, 42, 1449-1469. doi: 10.1007/s40264-019-00854-x

Journal - Research Article

Kuan, I. H. S., Duffull, S. B., Putt, T. L., Schollum, J. B. W., Walker, R. J., & Wright, D. F. B. (2017). A population pharmacokinetic model for 51Cr EDTA to estimate renal function. Clinical Pharmacokinetics, 56(6), 671-678. doi: 10.1007/s40262-016-0489-x

Journal - Research Article

Kuan, I. H. S., Wright, D. F. B., Duffull, S. B., & Zhu, X. (2020). Understanding the association between metformin plasma concentrations and lactate. British Journal of Clinical Pharmacology, 87(2), 700-701. doi: 10.1111/bcp.14394

Journal - Research Other

Sinnappah, K. A., Kuan, I. H. S., Thynne, T. R. J., Doogue, M. P., & Wright, D. F. B. (2020). The pharmacokinetics of metformin in patients receiving intermittent haemodialysis [Short report]. British Journal of Clinical Pharmacology, 86, 1430-1443. doi: 10.1111/bcp.14244

Journal - Research Other

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