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Physiology profile

Ruben Vergara Silva

PositionPhD Student
DepartmentDepartment of Physiology
QualificationsBSc BSc(Hons)
Research summaryRyanodine receptor: The next target for Alzheimer's disease


My principal research interest is in the role of ryanodine receptor (RyR2) in Alzheimer's disease (AD). In particular, my focus is in understanding RyR2 function and its organisation in AD.

RyR2 has been shown to be involved in both AD and heart disease. Therefore, we aim to characterise how the activity of RyR2 is altered in disease and how it can be restored to its normal function.