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Physiology profile

Dr Jenny Clarkson

PositionResearch Fellow
DepartmentDepartment of Physiology
QualificationsPhD
Research summaryKisspeptin and fertility

Research

Jenny is working in Prof Allan Herbison's laboratory. Her research centres around dissecting the critical role of kisspeptin neurons in the control of fertility.

Publications

Clarkson, J., & Herbison, A. E. (2006). Postnatal development of kisspeptin neurons in mouse hypothalamus: Sexual dimorphism and projections to gonadotropin-releasing hormone neurons. Endocrinology, 147(12), 5817-5825.

Clarkson, J., d'Anglemont de Tassigny, X., Santos Moreno, A., Colledge, W. H., & Herbison, A. E. (2008). Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge. Journal of Neuroscience, 28(35), 8691-8697. doi: 10.1523/JNEUROSCI.1775-08.2008

Clarkson, J., Boon, W. C., Simpson, E. R., & Herbison, A. E. (2009). Postnatal development of an estradiol-kisspeptin positive feedback mechanism implicated in puberty onset. Endocrinology, 150(7), 3214-3220. doi: 10.1210/en.2008-1733

Clarkson, J., d'Anglemont de Tassigny, X., Colledge, W. H., Caraty, A., & Herbison, A. E. (2009). Distribution of kisspeptin neurones in the adult female mouse brain. Journal of Neuroendocrinology, 21(8), 673-682. doi: 10.1111/j.1365-2826.2009.01892.x

Clarkson, J. (2013). Effects of estradiol on kisspeptin neurons during puberty. Frontiers in Neuroendocrinology, 34, 120-131. doi: 10.1016/j.yfrne.2013.02.002

Clarkson, J., & Herbison, A. E. (2006). Postnatal development of kisspeptin neurons in mouse hypothalamus: Sexual dimorphism and projections to gonadotropin-releasing hormone neurons. Endocrinology, 147(12), 5817-5825.

Journal - Research Article

Clarkson, J., d'Anglemont de Tassigny, X., Santos Moreno, A., Colledge, W. H., & Herbison, A. E. (2008). Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge. Journal of Neuroscience, 28(35), 8691-8697. doi: 10.1523/JNEUROSCI.1775-08.2008

Journal - Research Article

Clarkson, J., Boon, W. C., Simpson, E. R., & Herbison, A. E. (2009). Postnatal development of an estradiol-kisspeptin positive feedback mechanism implicated in puberty onset. Endocrinology, 150(7), 3214-3220. doi: 10.1210/en.2008-1733

Journal - Research Article

Clarkson, J., d'Anglemont de Tassigny, X., Colledge, W. H., Caraty, A., & Herbison, A. E. (2009). Distribution of kisspeptin neurones in the adult female mouse brain. Journal of Neuroendocrinology, 21(8), 673-682. doi: 10.1111/j.1365-2826.2009.01892.x

Journal - Research Article

Clarkson, J. (2013). Effects of estradiol on kisspeptin neurons during puberty. Frontiers in Neuroendocrinology, 34, 120-131. doi: 10.1016/j.yfrne.2013.02.002

Journal - Research Article

Clarkson, J., & Herbison, A. E. (2011). Dual phenotype kisspeptin-dopamine neurones of the rostral periventricular area of the third ventricle project to gonadotrophin-releasing hormone neurones. Journal of Neuroendocrinology, 23(4), 293-301. doi: 10.1111/j.1365-2826.2011.02107.x

Journal - Research Article

Clarkson, J., Shamas, S., Mallinson, S., & Herbison, A. E. (2012). Gonadal steroid induction of kisspeptin peptide expression in the rostral periventricular area of the third ventricle during postnatal development in the male mouse. Journal of Neuroendocrinology, 24(6), 907-915. doi: 10.1111/j.1365-2826.2012.02294.x

Journal - Research Article

Constantin, S., Piet, R., Iremonger, K., Yeo, S. H., Clarkson, J., Porteous, R., & Herbison, A. E. (2012). GnRH neuron firing and response to GABA in vitro depend on acute brain slice thickness and orientation. Endocrinology, 153(8), 3758-3769. doi: 10.1210/en.2012-1126

Journal - Research Article

Clarkson, J., & Herbison, A. E. (2006). Development of GABA and glutamate signaling at the GnRH neuron in relation to puberty. Molecular & Cellular Endocrinology, 254-255, 32-38.

Journal - Research Article

Clarkson, J., & Herbison, A. E. (2009). Oestrogen, kisspeptin, GPR54 and the pre-ovulatory luteinising hormone surge. Journal of Neuroendocrinology, 21(4), 305-311. doi: 10.1111/j.1365-2826.2009.01835.x

Journal - Research Article

Clarkson, J., Han, S.-K., Liu, X., Lee, K., & Herbison, A. E. (2010). Neurobiological mechanisms underlying kisspeptin activation of gonadotropin-releasing hormone (GnRH) neurons at puberty. Molecular & Cellular Endocrinology, 324, 45-50. doi: 10.1016/j.mce.2010.01.026

Journal - Research Article

Kuo, J., Hamid, N., Bondar, G., Dewing, P., Clarkson, J., & Micevych, P. (2010). Sex differences in hypothalamic astrocyte response to estradiol stimulation. Biology of Sex Differences, 1, 7. doi: 10.1186/2042-6410-1-7

Journal - Research Article

Clarkson, A. N., Clarkson, J., Jackson, D. M., & Sammut, I. A. (2007). Mitochondrial involvement in transhemispheric diaschisis following hypoxia-ischemia: Clomethiazole-mediated amelioration. Neuroscience, 144, 547-561.

Journal - Research Article

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