Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Munro Lab

^ Top of Page

Research interests

I am interested in how the cardiac ultrastructure impacts the function of the heart, in particular the organisation of specialised structures known as the dyad and transverse tubules. I am investigating how these structures are remodelled in atrial fibrillation and heart failure, and whether specific proteins can be targeted to restore cardiac organisation and function in heart disease.

^ Top of Page

Projects

  • Restoration of calcium balance by calsequestrin in atrial fibrillation

^ Top of Page

Current funding

  • 2019–2022: Heart Foundation of New Zealand Research Fellowship
  • 2020–2022: Health Research Council Emerging Researcher First Grant

^ Top of Page

Previous funding

  • Heart Foundation of New Zealand small project grant

^ Top of Page

Publications

Munro, M. (2022, June). Biphasic regulation of RyR2 activity by calsequestrin-2: Implications in Ca-mediated arrhythmias. Invited presentation at the XXIV World Congress of the International Society for Heart Research (ISHR), Berlin, Germany.

Parveen, S., Cheah, P. H. S., Worthington, L. P. I., Smither, R. A., Munro, M. L., Bussey, C. T., Lamberts, R. R., & Jones, P. P. (2022). Depressed HCN4 function in the type 2 diabetic sinoatrial node. Molecular & Cellular Biochemistry. Advance online publication. doi: 10.1007/s11010-022-04635-6

Waddell, H. M. M., de Jonge, W. M., & Munro, M. L. (2022, August-September). Preparation of functional human atrial slices and multi-day tissue culture. Poster session presented at the New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Iposu, K. O., Waddell, H. M. M., & Munro, M. L. (2022, August-September). Characterisation of t-tubules and dyads in human atrial myocytes. Poster session presented at the New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Sibbles, E., Jones, P., & Munro, M. (2022, August-September). Determining the functional effect of CSQ2 glycosylation on calcium-handling and heart failure. Verbal presentation at the New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.