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Identifying the best source of stem cells for the regeneration of diseased heart

A postgraduate research opportunity at the University of Otago.

Details

Close date
Friday, 8 December 2017
Academic background
Sciences, Health Sciences
Host campus
Dunedin
Qualification
PhD
Department
Physiology
Supervisor
Associate Professor Rajesh Katare

Overview

Autologous stem cell transplantation is considered as the next generation of drug treatment in patients with cardiovascular disease. However, the best source of stem cells for the regeneration of heart is still not known. This project in collaboration with the cardiac surgeons at Dunedin Hospital will aim to establish the optimal stem cells for the treatment of patients with cardiovascular disease. The project involves isolation and characterization (using flowcytometry) of stem cells from the atria, ventricle, epicardial fat tissue and peripheral blood and saphenous vein of a single donor. Protocol for isolation and characterization of some of these cells have been already established in my laboratory. The efficacy of the cells will be then tested in the animal model of cardiovascular disease to identify the best cells for regenerating the diseased heart.

Contact

Associate Professor Rajesh Katare
Tel   64 3 479 7292
Email   rajesh.katare@otago.ac.nz