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MICR334 Advanced Immunology

Mechanisms of immune activation and tolerance, molecular immunology, allergy, autoimmunity, immunodeficiency, immunoendocrinology, tumour immunotherapy and transplant immunology. Tools for tumour immunotherapy, fluorescent cell sorting, lymphocyte activation, cytotoxicity and cytokine assays.

The immune system helps determine how our bodies respond to infections, allergens, transplantation and cancer. Understanding how it functions is essential for the development of effective vaccines and treatments. This paper will demonstrate how the immune system functions and give you the opportunity to see how your knowledge can be applied.

A course in immunology opens up career possibilities in fields as diverse as influenza vaccine development, cancer immunology and autoimmunity. This paper will build on your fundamental knowledge of immunology. This paper is ideal if you want to explore and develop your understanding of the immune system and investigate the application of immunology knowledge at the interface between disease and the host response to disease.

Paper title Advanced Immunology
Paper code MICR334
Subject Microbiology
EFTS 0.15
Points 18 points
Teaching period Semester 1 (On campus)
Domestic Tuition Fees (NZD) $1,141.35
International Tuition Fees Tuition Fees for international students are elsewhere on this website.

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Prerequisite
MICR 223
Recommended Preparation
MICR 221
Schedule C
Science
Eligibility
Appropriate for BSc or BBiomedSc students.
Contact

Professor Roslyn Kemp: roslyn.kemp@otago.ac.nz

Teaching staff

Convenor: Professor Roslyn Kemp
Other Lecturers: Professor Alex McLellan
Associate Professor Jo Kirman
Megan Hall

Paper Structure

The lectures focus on:

  • Comparative Immunity and Innate Immune Responses Antigen Recognition and Presentation
  • Lab Preparation
  • T Cell Immunology
  • B Cell Immunology
  • Immune Memory and Vaccines

The laboratory course investigates T cell heterogeneity. In these labs, you will work in groups to design and carry out experiments to culture T cell populations and to change them into different populations. Several protocols will be provided to help you.

Assessment:

  • Poster for Practical Component (20%)
  • Blackboard Quiz on lab content (10%)
  • Final Exam (70%)
Teaching Arrangements

Twenty-four lectures
Four weeks of practical work (12 hours/week)

There are two lectures per week for all weeks of the first semester. There is one laboratory session per week, with each laboratory session running over 2-4 days. Students may leave the lab for other commitments, such as lectures, and are able to plan their experiments to fit in with these commitments. The laboratory classes run in weeks 5-8 of the first semester.

Textbooks

Textbooks are not required for this paper.

Course outline

Contact the course convenor for a course outline.

Graduate Attributes Emphasised
Scholarship, Communication, Critical thinking, Ethics, Information literacy, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes

Students who successfully complete this paper will:

  • Build on fundamental knowledge of immunology
  • Investigate the application of immunology knowledge at the interface between disease and the host response to disease

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Timetable

Semester 1

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
A1 Tuesday 13:00-13:50 9-14, 16, 18-22
Friday 13:00-13:50 9-13, 16-22

Practical

Stream Days Times Weeks
Attend one stream from
A1 Monday 14:00-17:50 13-14, 16-17
Tuesday 09:00-12:50 13-14, 16
Tuesday 14:00-17:50 13-14, 16-17
Wednesday 09:00-09:50 13-14, 16-17
A2 Monday 14:00-17:50 13-14, 16-17
Tuesday 09:00-12:50 13-14, 16
Tuesday 14:00-17:50 13-14, 16-17
Wednesday 10:00-10:50 13-14, 16-17
A3 Monday 14:00-17:50 13-14, 16-17
Tuesday 09:00-12:50 13-14, 16
Tuesday 14:00-17:50 13-14, 16-17
Wednesday 11:00-11:50 13-14, 16-17
A4 Wednesday 14:00-17:50 13-14, 16-17
Thursday 09:00-17:50 13-14, 16-17
Friday 09:00-09:50 13, 16-17
A5 Wednesday 14:00-17:50 13-14, 16-17
Thursday 09:00-17:50 13-14, 16-17
Friday 10:00-10:50 13, 16-17
A6 Wednesday 14:00-17:50 13-14, 16-17
Thursday 09:00-17:50 13-14, 16-17
Friday 11:00-11:50 13, 16-17