The epithelial and integrative functions of the gastrointestinal and renal systems of the human body will be examined at the cellular and molecular levels. Examples of pathophysiological conditions will be highlighted.
PHSL 233 builds on and extends the renal/urinary and gastrointestinal system topics introduced in HUBS 192.
| Paper title | Cellular, Gastrointestinal and Renal Physiology |
|---|---|
| Paper code | PHSL233 |
| Subject | Physiology |
| EFTS | 0.15 |
| Points | 18 points |
| Teaching period | Semester 2 (On campus) |
| Domestic Tuition Fees (NZD) | $1,141.35 |
| International Tuition Fees | Tuition Fees for international students are elsewhere on this website. |
- Prerequisite
- HUBS 191 and HUBS 192 and two of BIOC 192, CELS 191, CHEM 191, PHSI 191
- Restriction
- MELS 251, PHCY 251, PHSL 251, PHTY 251
- Recommended Preparation
- PHSL 231
- Schedule C
- Science
- Eligibility
- Essential for Physiology, and Functional Human Biology majors
- Contact
- phsl.231-2-3@otago.ac.nz
- More information link
View more information on the Department of Physiology's website
- Teaching staff
Convener: Dr Andrew Bahn
Lecturers: Dr Mike Gill
Associate Professor Kirk Hamilton
Please note: Teaching staff maybe subject to change.
- Paper Structure
The lecture blocks will focus on:
- Cellular physiology
- Introduction to epithelia
- Cellular communication and signaling in epithelia
- Epithelial polarity and protein trafficking
- Renal system
- Gastrointestinal system
Six laboratories will give you skills in a range of techniques:
- Passive movement of solutes through cell membranes, osmosis
- Glucose transport into everted sacs of the small intestine
- The properties of epithelia
- Renal function
- DNA analysis of the ENaC and ROMK1 genes
- Smooth muscle contraction
Assessment:
- Internal assessment (40%) comprises two evening progress tests
- Final examination comprises 60% of the final grade
- Teaching Arrangements
- You will attend 2 or 3 lectures each week and a laboratory session on alternate weeks.
- Textbooks
The primary textbook for this paper is 'Berne & Levy Physiology', 7th edn, 2018, eds. Koeppen & Stanton.
- Graduate Attributes Emphasised
- Lifelong learning, Scholarship, Communication, Critical thinking, Ethics, Research,
Self-motivation, Teamwork.
View more information about Otago's graduate attributes. - Learning Outcomes
Students who successfully complete this paper will:
- Acquire extensive knowledge of the physiology of the renal and gastrointestinal systems and some pathophysiological conditions that affect epithelial tissues
- Master skills to study epithelial characteristics
- Develop an understanding of ethics in physiology
