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A postgraduate research opportunity at the University of Otago.

Details

Close date
Thursday, 30 November 2023
Academic background
Health Sciences
Host campus
Dunedin
Qualifications
Master's, PhD
Department
Pathology (Dunedin)
Supervisor
Dr Adele Woolley

Overview

Osteoarthritis (OA) is a debilitating disease which is projected to affect increasing numbers of our aging population, posing an ongoing and significant health and economic burden to New Zealand.

OA is the most common form of arthritis and is traditionally associated with mechanical 'wear and tear'. There are limited therapeutic options available, resulting in prolonged disability and decreased quality of life, until the advent of end stage joint replacement. Recent research has found that patients may suffer from different types of OA which are due to a variety of factors including some which are driven by inflammation.

This proposal aims to identify inflammatory biomarkers in patients with this inflammatory subtype which will lead to both early intervention and to greatly improved health outcomes.

This project uses immunofluorescence to label specific proteins in patient tissue before imaging using microscopy. It also involves the use of RNAScope to label specific transcripts within the cells

Contact

Dr Adele Woolley
Emailadele.woolley@otago.ac.nz

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