Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Determine the contribution of the p53 isoform, Δ133p53, in the development of bowel inflammation and IBD

A postgraduate research opportunity at the University of Otago.


Academic background
Health Sciences
Host campus
Postgraduate Diploma, Honours, Master’s
Pathology (Dunedin)
Dr Kunyu Li, Professor Antony Braithwaite


The p53 was originally known to function as a tumour suppressor gene that prevents cellular transformation and cancer development. Recent studies have shown that the p53 family also plays a regulatory role in the immune response. Our previous studies show that one of its isoforms, namely Δ133p53, has a pro-inflammatory function in both cancer and autoimmune conditions.

This project aims to determine the contribution of Δ133p53 isoform in Inflammatory Bowel Disease (IBD), using both a mouse model of colitis and samples from IBD patients.

Students with substantial knowledge in IBD, inflammation, and immunology are desired.


Kunyu Li
Tel   +64 21 155 9148