Phone +64 3 479 5019
Email sandhya.ramrakha@otago.ac.nz
Sandhya is the Research manager for the Dunedin Multidisciplinary Health and Development Study. Her role includes research administrative support to the Director and to the Dunedin Study Theme leaders, as well as the management of the assessment phases of the Dunedin Study. She has previously worked as a clinical psychologist in the New South Wales Department of Corrective Services in Australia.
Research Interests
Sandhya's PhD used Dunedin Study data to examine the links between mental and sexual health, with specific reference to risky sexual behaviour. Her current research interest involves examining the mental health and psychosocial correlates and consequences of skin conditions.
Publications
Brennan, G. M., Moffitt, T. E., Ambler, A., Harrington, H., Hogan, S., Houts, R. M., Mani, R., Poulton, R., Ramrakha, S., & Caspi, A. (2023). Tracing the origins of midlife despair: Association of psychopathology during adolescence with a syndrome of despair-related maladies at midlife. Psychological Medicine. Advance online publication. doi: 10.1017/S0033291723001320
Whitman, E. T., Knodt, A. R., Elliott, M. L., Abraham, W. C., Cheyne, K., Hogan, S., Ireland, D., Keenan, R., Leung, J. H., Melzer, T. R., Poulton, R., Purdy, S., Ramrakha, S., … Hariri, A. R. (2023). Functional topography of the neocortex predicts covariation in complex cognitive and basic motor abilities. Cerebral Cortex, bhad109. Advance online publication. doi: 10.1093/cercor/bhad109
Sugden, K., Moffitt, T. E., Arpawong, T. E., Arseneault, L., Belsky, D. W., Corcoran, D. L., … Poulton, R., Ramrakha, S., … Caspi, A. (2023). Cross-national and cross-generational evidence that educational attainment may slow the pace of aging in European-descent individuals. Journals of Gerontology Series B. Advance online publication. doi: 10.1093/geronb/gbad056
Bourassa, K. J., Caspi, A., Brennan, G. M., Hall, K. S., Harrington, H., Houts, R., … Poulton, R., Ramrakha, S., … Moffitt, T. E. (2023). Which types of stress are associated with accelerated biological aging? Comparing perceived stress, stressful life events, childhood adversity, and posttraumatic stress disorder. Psychosomatic Medicine. Advance online publication. doi: 10.1097/psy.0000000000001197
Barrett-Young, A., Abraham, W. C., Cheung, C. Y., Gale, J., Hogan, S., Ireland, D., Keenan, R., … Melzer, T. R., Moffitt, T. E., Ramrakha, S., … Wilson, G. A., … Poulton, R. (2023). Associations between thinner retinal neuronal layers and suboptimal brain structural integrity in a middle-aged cohort. Eye & Brain, 15, 25-35. doi: 10.2147/EB.S402510
Barrett-Young, A., Abraham, W. C., Cheung, C. Y., Gale, J., Hogan, S., Ireland, D., Keenan, R., … Melzer, T. R., Moffitt, T. E., Ramrakha, S., … Wilson, G. A., … Poulton, R. (2023). Associations between thinner retinal neuronal layers and suboptimal brain structural integrity in a middle-aged cohort. Eye & Brain, 15, 25-35. doi: 10.2147/EB.S402510
Journal - Research Article
Bourassa, K. J., Caspi, A., Brennan, G. M., Hall, K. S., Harrington, H., Houts, R., … Poulton, R., Ramrakha, S., … Moffitt, T. E. (2023). Which types of stress are associated with accelerated biological aging? Comparing perceived stress, stressful life events, childhood adversity, and posttraumatic stress disorder. Psychosomatic Medicine. Advance online publication. doi: 10.1097/psy.0000000000001197
Journal - Research Article
Brennan, G. M., Moffitt, T. E., Ambler, A., Harrington, H., Hogan, S., Houts, R. M., Mani, R., Poulton, R., Ramrakha, S., & Caspi, A. (2023). Tracing the origins of midlife despair: Association of psychopathology during adolescence with a syndrome of despair-related maladies at midlife. Psychological Medicine. Advance online publication. doi: 10.1017/S0033291723001320
Journal - Research Article
Sugden, K., Moffitt, T. E., Arpawong, T. E., Arseneault, L., Belsky, D. W., Corcoran, D. L., … Poulton, R., Ramrakha, S., … Caspi, A. (2023). Cross-national and cross-generational evidence that educational attainment may slow the pace of aging in European-descent individuals. Journals of Gerontology Series B. Advance online publication. doi: 10.1093/geronb/gbad056
Journal - Research Article
Whitman, E. T., Knodt, A. R., Elliott, M. L., Abraham, W. C., Cheyne, K., Hogan, S., Ireland, D., Keenan, R., Leung, J. H., Melzer, T. R., Poulton, R., Purdy, S., Ramrakha, S., … Hariri, A. R. (2023). Functional topography of the neocortex predicts covariation in complex cognitive and basic motor abilities. Cerebral Cortex, bhad109. Advance online publication. doi: 10.1093/cercor/bhad109
Journal - Research Article
Wilson, G. A., Cheyne, K., Ramrakha, S., Ambler, A., Tan, G. S. W., Caspi, A., … Poulton, R. (2023). Are macular drusen in midlife a marker of accelerated biological ageing? Clinical & Experimental Optometry, 106(1), 41-46. doi: 10.1080/08164622.2021.2012428
Journal - Research Article
Bourassa, K. J., Moffitt, T. E., Ambler, A., Hariri, A. R., Harrington, H., Houts, R. M., Ireland, D., Knodt, A., Poulton, R., Ramrakha, S., & Caspi, A. (2022). Association of treatable health conditions during adolescence with accelerated aging at midlife. JAMA Pediatrics. Advance online publication. doi: 10.1001/jamapediatrics.2021.6417
Journal - Research Article
Bourassa, K. J., Moffitt, T. E., Harrington, H., Houts, R., Poulton, R., Ramrakha, S., … Caspi, A. (2022). Childhood adversity and midlife health: Shining a light on the black box of psychosocial mechanisms. Prevention Science. Advance online publication. doi: 10.1007/s11121-022-01431-y
Journal - Research Article
Carlisi, C. O., Moffitt, T. E., Knodt, A. R., Harrington, H., Langevin, S., Ireland, D., Melzer, T. R., Poulton, R., Ramrakha, S., Caspi, A., … Viding, E. (2022). Association of subcortical gray-matter volumes with life-course-persistent antisocial behavior in a population-representative longitudinal birth cohort. Development & Psychopathology, 34(5), 2012-2022. doi: 10.1017/S0954579421000377
Journal - Research Article
Guiney, H., Caspi, A., Ambler, A., Belsky, J., Kokaua, J., Broadbent, J., Cheyne, K., Dickson, N., Hancox, R. J., Harrington, H., Hogan, S., Ramrakha, S., Righarts, A., Thomson, W. M., … Poulton, R. (2022). Childhood sexual abuse and pervasive problems across multiple life domains: Findings from a five-decade study. Development & Psychopathology. Advance online publication. doi: 10.1017/S0954579422001146
Journal - Research Article
Knodt, A. R., Meier, M. H., Ambler, A., Gehred, M. Z., Harrington, H., Ireland, D., Poulton, R., Ramrakha, S., Caspi, A., Moffitt, T. E., & Hariri, A. R. (2022). Diminished structural brain integrity in long-term cannabis users reflects a history of polysubstance use. Biological Psychiatry. Advance online publication. doi: 10.1016/j.biopsych.2022.06.018
Journal - Research Article
Langevin, S., Caspi, A., Barnes, J. C., Brennan, G., Poulton, R., Purdy, S. C., Ramrakha, S., … Moffitt, T. E. (2022). Life-course persistent antisocial behavior and accelerated biological aging in a longitudinal birth cohort. International Journal of Environmental Research & Public Health, 19, 14402. doi: 10.3390/ijerph192114402
Journal - Research Article
Meier, M. H., Caspi, A., Ambler, A., Hariri, A. R., Harrington, H., Hogan, S., … Ramrakha, S., … Poulton, R., & Moffitt, T. E. (2022). Preparedness for healthy ageing and polysubstance use in long-term cannabis users: A population-representative longitudinal study. Lancet Healthy Longevity, 3(10), 703-714. doi: 10.1016/S2666-7568(22)00201-X
Journal - Research Article
Meier, M. H., Caspi, A., Knodt, A. R., Hall, W., Ambler, A., Harrington, H., Hogan, S., … Poulton, R., Ramrakha, S., … Moffitt, T. E. (2022). Long-term cannabis use and cognitive reserves and hippocampal volume in midlife. American Journal of Psychiatry. Advance online publication. doi: 10.1176/appi.ajp.2021.21060664
Journal - Research Article
Meredith-Jones, K., Haszard, J., Taylor, R., Waters, D., Hogan, S., Ramrakha, S., & Poulton, R. (2022). Is repeated childhood fracture related to areal bone density or body composition in middle age? Osteoporosis International, 33, 2369-2379. doi: 10.1007/s00198-022-06500-0
Journal - Research Article
Moffitt, T. E., Caspi, A., Ambler, A., Bourassa, K., Harrington, H., Hogan, S., … Ramrakha, S., … Poulton, R. (2022). Deep-seated psychological histories of COVID-19 vaccine hesitance and resistance. PNAS Nexus. Advance online publication. doi: 10.1093/pnasnexus/pgac034
Journal - Research Article
Poulton, R., Guiney, H., Ramrakha, S., & Moffitt, T. E. (2022). The Dunedin study after half a century: Reflections on the past, and course for the future. Journal of the Royal Society of New Zealand. Advance online publication. doi: 10.1080/03036758.2022.2114508
Journal - Research Article
Reuben, A., Moffitt, T. E., Abraham, W. C., Ambler, A., Elliott, M. L., Hariri, A. R., … Hogan, S., … Ireland, D., … Pearson, A., Poulton, R., … Ramrakha, S., … Wilson, G., & Caspi, A. (2022). Improving risk indexes for Alzheimer’s disease and related dementias for use in midlife. Brain Communications, 4(5), fcac223. doi: 10.1093/braincomms/fcac223
Journal - Research Article
Ruiz, B., Broadbent, J. M., Thomson, W. M., Ramrakha, S. K., Boden, J., Horwood, L. J., & Poulton, R. (2022). Childhood caries experience in two Aotearoa New Zealand birth cohorts: Implications for research, policy and practice. Journal of the Royal Society of New Zealand. Advance online publication. doi: 10.1080/03036758.2022.2061018
Journal - Research Article
Ruiz, B., Broadbent, J. M., Thomson, W. M., Ramrakha, S., Boden, J., Horwood, J., & Poulton, R. (2022). Is childhood oral health the 'canary in the coal mine' for poor adult general health? Findings from two New Zealand birth cohort studies. Community Dentistry & Oral Epidemiology. Advance online publication. doi: 10.1111/cdoe.12772
Journal - Research Article
Slutske, W. S., Richmond-Rakerd, L. S., Piasecki, T. M., Ramrakha, S., Poulton, R., Moffitt, T. E., & Caspi, A. (2022). Disordered gambling in a longitudinal birth cohort: From childhood precursors to adult life outcomes. Psychological Medicine. Advance online publication. doi: 10.1017/S0033291722003051
Journal - Research Article
Baldwin, J. R., Caspi, A., Meehan, A. J., Ambler, A., Arseneault, L., Fisher, H. L., Harrington, H., … Poulton, R., Ramrakha, S., Moffitt, T. E., & Danese, A. (2021). Population vs individual prediction of poor health from results of adverse childhood experiences screening. JAMA Pediatrics, 175(4), 385-393. doi: 10.1001/jamapediatrics.2020.5602
Journal - Research Article
Bourassa, K. J., Moffitt, T. E., Harrington, H., Houts, R., Poulton, R., Ramrakha, S., & Caspi, A. (2021). Lower cardiovascular reactivity is associated with more childhood adversity and poorer midlife health: Replicated findings from the Dunedin and MIDUS cohorts. Clinical Psychological Science, 9(5), 961-978. doi: 10.1177/2167702621993900
Journal - Research Article
Bourassa, K. J., Rasmussen, L. J. H., Danese, A., Eugen-Olsen, J., Harrington, H., Houts, R., Poulton, R., Ramrakha, S., … Moffitt, T. E., & Caspi, A. (2021). Linking stressful life events and chronic inflammation using suPAR (soluble urokinase plasminogen activator receptor). Brain, Behavior & Immunity, 97, 79-88. doi: 10.1016/j.bbi.2021.06.018
Journal - Research Article
d'Arbeloff, T., Elliott, M. L., Knodt, A. R., Sison, M., Melzer, T. R., Ireland, D., Ramrakha, S., Poulton, R., Caspi, A., Moffitt, T. E., & Hariri, A. R. (2021). Midlife cardiovascular fitness is reflected in the brain's white matter. Frontiers in Aging Neuroscience, 13, 652575. doi: 10.3389/fnagi.2021.652575
Journal - Research Article
Elliott, M. L., Belsky, D. W., Knodt, A. R., Ireland, D., Melzer, T. R., Poulton, R., Ramrakha, S., Caspi, A., Moffitt, T. E., & Hariri, A. R. (2021). Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort. Molecular Psychiatry, 26, 3829-3838. doi: 10.1038/s41380-019-0626-7
Journal - Research Article
Elliott, M. L., Caspi, A., Houts, R. M., Ambler, A., Broadbent, J. M., Hancox, R. J., … Hogan, S., Keenan, R., … Melzer, T. R., … Ramrakha, S., … Righarts, A., … Thomson, W. M., Thorne, P. R., … Wilson, G., … Poulton, R., & Moffitt, T. E. (2021). Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy. Nature Aging, 1(3), 295-308. doi: 10.1038/s43587-021-00044-4
Journal - Research Article
Gehred, M. Z., Knodt, A. R., Ambler, A. P., Bourassa, K. J., Danese, A., Elliott, M. L., Hogan, S., Ireland, D., Poulton, R., Ramrakha, S., … Caspi, A. (2021). Long-term neural embedding of childhood adversity in a population-representative birth cohort followed for five decades. Biological Psychiatry, 90, 182-193. doi: 10.1016/j.biopsych.2021.02.971
Journal - Research Article
Mason, D., Ronald, A. R., Ambler, A., Caspi, A., Houts, R., Poulton, R., Ramrakha, S., … Moffitt, T. E., & Happé, F. (2021). Autistic traits are associated with faster pace of aging: Evidence from the Dunedin study at age 45. Autism Research, 14, 1684-1694. doi: 10.1002/aur.2534
Journal - Research Article
Rasmussen, L. J. H., Caspi, A., Ambler, A., Danese, A., Elliott, M., Eugen-Olsen, J., … Harrington, H., … Poulton, R., Ramrakha, S., … Moffitt, T. E. (2021). Association between elevated suPAR, a new biomarker of inflammation, and accelerated aging. Journals of Gerontology Series A, 76(2), 318-327. doi: 10.1093/gerona/glaa178
Journal - Research Article
Richmond-Rakerd, L. S., Caspi, A., Ambler, A., d'Arbeloff, T., de Bruine, M., Elliott, M., … Hogan, S., … Ireland, D., … Poulton, R., Ramrakha, S., … Moffitt, T. E. (2021). Childhood self-control forecasts the pace of midlife aging and preparedness for old age. PNAS, 118(3), e2010211118. doi: 10.1073/pnas.2010211118
Journal - Research Article
Romer, A. L., Elliott, M. L., Knodt, A. R., Sison, M. L., Ireland, D., Houts, R., Ramrakha, S., Poulton, R., Keenan, R., Melzer, T. R., … Hariri, A. R. (2021). Pervasively thinner neocortex as a transdiagnostic feature of general psychopathology. American Journal of Psychiatry, 178(2), 174-182. doi: 10.1176/appi.ajp.2020.19090934
Journal - Research Article
Romer, A. L., Knodt, A. R., Sison, M. L., Ireland, D., Houts, R., Ramrakha, S., Poulton, R., Keenan, R., Melzer, T. R., Moffitt, T. E., Caspi, A., & Hariri, A. R. (2021). Replicability of structural brain alterations associated with general psychopathology: Evidence from a population-representative birth cohort. Molecular Psychiatry, 26, 3839-3846. doi: 10.1038/s41380-019-0621-z
Journal - Research Article
Wertz, J., Caspi, A., Ambler, A., Broadbent, J., Hancox, R. J., Harrington, H., Hogan, S., … Leung, J. H., Poulton, R., … Ramrakha, S., … Thorne, P. R., Wilson, G. A., & Moffitt, T. E. (2021). Association of history of psychopathology with accelerated aging at midlife. JAMA Psychiatry, 78(5), 530-539. doi: 10.1001/jamapsychiatry.2020.4626
Journal - Research Article
Bourassa, K. J., Caspi, A., Harrington, H., Houts, R., Poulton, R., Ramrakha, S., & Moffitt, T. E. (2020). Intimate partner violence and lower relationship quality are associated with faster biological aging. Psychology & Aging, 35(8), 1127-1139. doi: 10.1037/pag0000581
Journal - Research Article
Carlisi, C. O., Moffitt, T. E., Knodt, A. R., Harrington, H., Ireland, D., Melzer, T. R., Poulton, R., Ramrakha, S., … Viding, E. (2020). Associations between life-course-persistent antisocial behaviour and brain structure in a population-representative longitudinal birth cohort. Lancet Psychiatry, 7(3), 245-253. doi: 10.1016/s2215-0366(20)30002-x
Journal - Research Article
Caspi, A., Houts, R. M., Ambler, A., Danese, A., Elliott, M. L., Hariri, A., … Hogan, S., Poulton, R., Ramrakha, S., … Moffitt, T. E. (2020). Longitudinal assessment of mental health disorders and comorbidities across 4 decades among participants in the Dunedin Birth Cohort Study. JAMA Network Open, 3(4), e203221. doi: 10.1001/jamanetworkopen.2020.3221
Journal - Research Article
d'Arbeloff, T., Cooke, M., Knodt, A. R., Sison, M., Melzer, T. R., Ireland, D., Poulton, R., Ramrakha, S., Moffitt, T. E., Caspi, A., & Hariri, A. R. (2020). Is cardiovascular fitness associated with structural brain integrity in midlife? Evidence from a population-representative birth cohort study. Aging, 12(20), 20888-20914. doi: 10.18632/aging.104112
Journal - Research Article
Elliott, M. L., Knodt, A. R., Ireland, D., Morrison, M. L., Poulton, R., Ramrakha, S., … Hariri, A. R. (2020). What is the test-retest reliability of common task-functional MRI measures? New empirical evidence and a meta-analysis. Psychological Science, 31(7), 792-806. doi: 10.1177/0956797620916786
Journal - Research Article
Reuben, A., Elliott, M. L., Abraham, W. C., Broadbent, J., Houts, R. M., Ireland, D., Knodt, A. R., Poulton, R., Ramrakha, S., … Caspi, A., & Moffitt, T. E. (2020). Association of childhood lead exposure with MRI measurements of structural brain integrity in midlife. JAMA, 324(19), 1970-1979. doi: 10.1001/jama.2020.19998
Journal - Research Article
Richmond-Rakerd, L. S., D'Souza, S., Andersen, S. H., Hogan, S., Houts, R. M., Poulton, R., Ramrakha, S., … Milne, B. J., & Moffitt, T. E. (2020). Clustering of health, crime and social-welfare inequality in 4 million citizens from two nations. Nature Human Behaviour, 4, 255-264. doi: 10.1038/s41562-019-0810-4
Journal - Research Article
Richmond-Rakerd, L. S., Moffitt, T. E., Arseneault, L., Belsky, D. W., Connor, J., Corcoran, D. L., … Poulton, R., … Ramrakha, S., … Caspi, A. (2020). A polygenic score for age-at-first-birth predicts disinhibition. Journal of Child Psychology & Psychiatry, 61(12), 1346-1359. doi: 10.1111/jcpp.13224
Journal - Research Article
d'Arbeloff, T., Elliott, M. L., Knodt, A. R., Melzer, T. R., Keenan, R., Ireland, D., Ramrakha, S., Poulton, R., Anderson, T., … Hariri, A. R. (2019). White matter hyperintensities are common in midlife and already associated with cognitive decline. Brain Communications, 1(1), fcz041. doi: 10.1093/braincomms/fcz041
Journal - Research Article
Elliott, M. L., Knodt, A. R., Cooke, M., Kim, M. J., Melzer, T. R., Keenan, R., Ireland, D., Ramrakha, S., Poulton, R., … Hariri, A. R. (2019). General functional connectivity: Shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks. NeuroImage, 189, 516-532. doi: 10.1016/j.neuroimage.2019.01.068
Journal - Research Article
Rasmussen, L. J. H., Caspi, A., Ambler, A., Broadbent, J. M., Cohen, H. J., d'Arbeloff, T., … Hancox, R. J., … Hogan, S., … Ireland, D., Knodt, A. R., Meredith-Jones, K., … Morrison, L., Poulton, R., Ramrakha, S., … Sneddon, K., Thomson, W. M., … Moffitt, T. E. (2019). Association of neurocognitive and physical function with gait speed in midlife. JAMA Network Open, 2(10), e1913123. doi: 10.1001/jamanetworkopen.2019.13123
Journal - Research Article
Reuben, A., Schaefer, J. D., Moffitt, T. E., Broadbent, J., Harrington, H., Houts, R. M., Ramrakha, S., Poulton, R., & Caspi, A. (2019). Association of childhood lead exposure with adult personality traits and lifelong mental health. JAMA Psychiatry, 76(4), 418-425. doi: 10.1001/jamapsychiatry.2018.4192
Journal - Research Article
Wertz, J., Belsky, J., Moffitt, T. E., Belsky, D. W., Harrington, H., Avinun, R., Poulton, R., Ramrakha, S., & Caspi, A. (2019). Genetics of nurture: A test of the hypothesis that parents' genetics predict their observed caregiving. Developmental Psychology, 55(7), 1461-1472. doi: 10.1037/dev0000709
Journal - Research Article
Beckley, A. L., Caspi, A., Broadbent, J., Harrington, H., Houts, R. M., Poulton, R., Ramrakha, S., … Moffitt, T. E. (2018). Association of childhood blood lead levels with criminal offending. JAMA Pediatrics, 172(2), 166-173. doi: 10.1001/jamapediatrics.2017.4005
Journal - Research Article
Shearer, D. M., Thomson, W. M., Cameron, C. M., Ramrakha, S., Wilson, G., Wong, T. Y., Williams, M. J. A., McLean, R., Theodore, R., & Poulton, R. (2018). Periodontitis and multiple markers of cardiometabolic risk in the fourth decade: A cohort study. Community Dentistry & Oral Epidemiology, 46(6), 615-623. doi: 10.1111/cdoe.12414
Journal - Research Article
Theodore, R., Taumoepeau, M., Tustin, K., Gollop, M., Unasa, C., Kokaua, J., Taylor, N., Ramrakha, S., Hunter, J., & Poulton, R. (2018). Pacific university graduates in New Zealand: What helps and hinders completion. AlterNative, 14(2), 138-146. doi: 10.1177/1177180118764126
Journal - Research Article