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GENE222 Genes, Chromosomes and Populations

Eukaryote genomes and genome evolution; phylogenetics; cytogenetics and chromosomes; extensions of Mendelian genetics; genetic mapping in eukaryotes; genes in populations; quantitative genetics.

GENE 222 gives a broad coverage of all of the concepts that are central to modern eukaryote genetics including human genetics. As such it is directly relevant for students with an interest in any of the biological or biomedical sciences. The different parts of the paper are linked by a common theme of genetic analysis and the use of specific examples to illustrate general principles. The lecture course is complemented by a laboratory course that gives hands-on experience of many of the methods that are used in genetic analysis of eukaryotes.

Paper title Genes, Chromosomes and Populations
Paper code GENE222
Subject Genetics
EFTS 0.1500
Points 18 points
Teaching period Second Semester
Domestic Tuition Fees (NZD) $1,059.15
International Tuition Fees (NZD) $4,914.00

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Prerequisite
CELS 191 and 90 further points
Recommended Preparation
GENE 221 and BIOC 221
Schedule C
Science
Eligibility
Appropriate for students majoring in genetics, other biological and health sciences and molecular biotechnology.
Contact

genetics@otago.ac.nz

Teaching staff

Convenor: Professor Iain Lamont (Department of Biochemistry)
Other teaching staff: Professor Jon Waters (Department of Zoology), Dr Janice Lord (Department of Botany), Professor Tony Merriman (Department of Biochemistry), Dr Martyn Kennedy (Department of Pathology) and Dr Gillian MacKay (Genetics Programme)

Paper Structure
The lecture course is divided into seven blocks:
  • Eukaryote genomes and genome evolution
  • Phylogenetics
  • Cytogenetics and chromosomes
  • Extensions of Mendelian genetics
  • Genetic mapping in eukaryotes
  • Genes in populations
  • Quantitative genetics
The lecture course is complemented by a laboratory course, which provides training in data analysis and relevant genetic methods, including Mendelian genetics and linkage, cytogenetics, working with Drosophila, genomics, population genetics and quantitative genetics.
Teaching Arrangements
There are six weeks of laboratory classes, in three 2-week blocks, and students are assigned to one of two lab streams.
Textbooks

The recommended text book for GENE 221 is: Introduction to Genetic Analysis (Griffiths, Wessler, Carroll, Doebley), 11th Edition. Earlier editions of this book are also satisfactory if you have access to a copy.

Graduate Attributes Emphasised
Global perspective, Interdisciplinary perspective, Scholarship, Critical thinking, Self-motivation, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
The broad objectives of GENE 222 are to understand:
  • Genomic variation within and between species
  • How to construct and interpret phylogenetic trees
  • The origins and diagnostic features of karyotypic variation
  • The extensions of Mendelian genetics
  • How to test alternative genetic hypotheses
  • How to map monogenic and complex disease genes
  • How evolution is explained by principles of variation, heredity and selection
  • Quantitative traits and the norm of reaction
  • Heritability, QTLs and their uses

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Timetable

Second Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
A1 Monday 09:00-09:50 28-34
AND
B1 Tuesday 13:00-13:50 28-34, 36-41
AND
C1 Wednesday 12:00-12:50 28-34, 36-41

Practical

Stream Days Times Weeks
Attend one stream from
A1 Friday 14:00-15:50 30-31, 34, 36, 39-40
Friday 16:00-18:50 31, 36
A2 Friday 14:00-15:50 31, 36
Friday 16:00-18:50 30-31, 34, 36, 39-40
A3 Monday 14:00-15:50 31-32, 36-37, 40-41
Monday 16:00-18:50 32, 37
A4 Monday 14:00-15:50 32, 37
Monday 16:00-18:50 31-32, 36-37, 40-41

Eukaryote genomes and genome evolution; phylogenetics; cytogenetics and chromosomes; extensions of Mendelian genetics; genetic mapping in eukaryotes; genes in populations; quantitative genetics.

GENE 222 gives a broad coverage of all of the concepts that are central to modern eukaryote genetics including human genetics. As such it is directly relevant for students with an interest in any of the biological or biomedical sciences. The different parts of the paper are linked by a common theme of genetic analysis and the use of specific examples to illustrate general principles. The lecture course is complemented by a laboratory course that gives hands-on experience of many of the methods that are used in genetic analysis of eukaryotes.

Paper title Genes, Chromosomes and Populations
Paper code GENE222
Subject Genetics
EFTS 0.1500
Points 18 points
Teaching period Second Semester
Domestic Tuition Fees Tuition Fees for 2020 have not yet been set
International Tuition Fees Tuition Fees for international students are elsewhere on this website.

^ Top of page

Prerequisite
CELS 191 and 90 further points
Recommended Preparation
GENE 221 and BIOC 221
Schedule C
Science
Eligibility
Appropriate for students majoring in genetics, other biological and health sciences and molecular biotechnology.
Contact

genetics@otago.ac.nz

Teaching staff

Convenor: Professor Iain Lamont (Department of Biochemistry)
Other teaching staff: Professor Jon Waters (Department of Zoology), Dr Janice Lord (Department of Botany), Professor Tony Merriman (Department of Biochemistry), Dr Martyn Kennedy (Department of Pathology) and Dr Gillian MacKay (Genetics Programme)

Paper Structure
The lecture course is divided into seven blocks:
  • Eukaryote genomes and genome evolution
  • Phylogenetics
  • Cytogenetics and chromosomes
  • Extensions of Mendelian genetics
  • Genetic mapping in eukaryotes
  • Genes in populations
  • Quantitative genetics
The lecture course is complemented by a laboratory course, which provides training in data analysis and relevant genetic methods, including Mendelian genetics and linkage, cytogenetics, working with Drosophila, genomics, population genetics and quantitative genetics.
Teaching Arrangements

There are six weeks of laboratory classes, in three 2-week blocks, and students are assigned to one of four lab streams.

Textbooks

The recommended text book for GENE 221 is: Introduction to Genetic Analysis (Griffiths, Wessler, Carroll, Doebley), 11th Edition. Earlier editions of this book are also satisfactory if you have access to a copy.

Graduate Attributes Emphasised
Global perspective, Interdisciplinary perspective, Scholarship, Critical thinking, Self-motivation, Teamwork.
View more information about Otago's graduate attributes.
Learning Outcomes
The broad objectives of GENE 222 are to understand:
  • Genomic variation within and between species
  • How to construct and interpret phylogenetic trees
  • The origins and diagnostic features of karyotypic variation
  • The extensions of Mendelian genetics
  • How to test alternative genetic hypotheses
  • How to map monogenic and complex disease genes
  • How evolution is explained by principles of variation, heredity and selection
  • Quantitative traits and the norm of reaction
  • Heritability, QTLs and their uses

^ Top of page

Timetable

Second Semester

Location
Dunedin
Teaching method
This paper is taught On Campus
Learning management system
Blackboard

Lecture

Stream Days Times Weeks
Attend
A1 Monday 09:00-09:50 28-34
AND
B1 Tuesday 13:00-13:50 28-34, 36-41
AND
C1 Wednesday 12:00-12:50 28-34, 36-41

Practical

Stream Days Times Weeks
Attend one stream from
A1 Friday 14:00-15:50 30-31, 34, 36, 39-40
Friday 16:00-18:50 31, 36
A2 Friday 14:00-15:50 31, 36
Friday 16:00-18:50 30-31, 34, 36, 39-40
A3 Monday 14:00-15:50 31-32, 36-37, 40-41
Monday 16:00-18:50 32, 37
A4 Monday 14:00-15:50 32, 37
Monday 16:00-18:50 31-32, 36-37, 40-41