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Gretel Major

Research focus

Gretel is developing 3D hydrogel matrices with encapsulated adipocytes for fat grafting and in vitro models of breast cancer.

She is supervised by Professor Tim Woodfield and Associate Professor Khoon Lim.

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Publications

Mekhileri, N. V., Major, G., Lim, K., Mutreja, I., Chitcholtan, K., Phillips, E., Hooper, G., & Woodfield, T. (2022). Biofabrication of modular spheroids as tumour-scale microenvironments for drug screening. Advanced Healthcare Materials. Advance online publication. doi: 10.1002/adhm.202201581

Longoni, A., Major, G., Atienza-Roca, P., Wise, L., Hooper, G., Kieser, D., Woodfield, T., … Lim, K. (2022). Gelatin incorporation in VEGF-loaded PVA-Tyramine hydrogels to enhance cellular interaction and vascular infiltration. Tissue Engineering Part A, 28(Suppl. 3), (pp. 642). doi: 10.1089/ten.tea.2022.29036.abstracts

Major, G., Longoni, A., Simcock, J., Lim, K., & Woodfield, T. (2022). Developing next generation adipose tissue grafts for soft tissue reconstruction. Tissue Engineering Part A, 28(Suppl. 3), (pp. 187). doi: 10.1089/ten.tea.2022.29036.abstracts

Major, G. (2022, April). Developing next generation adipose tissue grafts for soft tissue reconstruction. Keynote presentation at the Australasian Society for Biomaterials and Tissue Engineering (ASBTE) 27th annual Conference, Melbourne, Australia.

Soliman, B. G., Major, G. S., Atienza-Roca, P., Murphy, C. A., Longoni, A., Alcala-Orozco, C. R., … Woodfield, T. B. F., & Lim, K. S. (2022). Development and characterization of gelatin-norbornene bioink to understand the interplay between physical architecture and micro-capillary formation in biofabricated vascularized constructs. Advanced Healthcare Materials, 11(2), 2101873. doi: 10.1002/adhm.202101873

Filipe, E. C., Parker, A. L., Cadell, A. L., Major, G., Croucher, D. R., & Cox, T. R. (2021). In vitro 3D models of tunable stiffness. In U. S. Stein (Ed.), Metastasis: Methods and Protocols: Methods in molecular biology (Vol. 2294). (pp. 27-42). New York, NY: Humana Press. doi: 10.1007/978-1-0716-1350-4_3

Chapter in Book - Research

Major, G. S., Simcock, J. W., Woodfield, T. B. F., & Lim, K. S. (2022). Overcoming functional challenges in autologous and engineered fat grafting trends. Trends in Biotechnology, 40(1), 77-92. doi: 10.1016/j.tibtech.2021.04.006

Journal - Research Article

Mekhileri, N. V., Major, G., Lim, K., Mutreja, I., Chitcholtan, K., Phillips, E., Hooper, G., & Woodfield, T. (2022). Biofabrication of modular spheroids as tumour-scale microenvironments for drug screening. Advanced Healthcare Materials. Advance online publication. doi: 10.1002/adhm.202201581

Journal - Research Article

Soliman, B. G., Major, G. S., Atienza-Roca, P., Murphy, C. A., Longoni, A., Alcala-Orozco, C. R., … Woodfield, T. B. F., & Lim, K. S. (2022). Development and characterization of gelatin-norbornene bioink to understand the interplay between physical architecture and micro-capillary formation in biofabricated vascularized constructs. Advanced Healthcare Materials, 11(2), 2101873. doi: 10.1002/adhm.202101873

Journal - Research Article

Perry, J., Ashford, B., Thind, A. S., Gauthier, M.-E., Minaei, E., Major, G., … Ranson, M. (2020). Comprehensive mutational and phenotypic characterization of new metastatic cutaneous squamous cell carcinoma cell lines reveal novel drug susceptibilities. International Journal of Molecular Sciences, 21(24), 9536. doi: 10.3390/ijms21249536

Journal - Research Article

Chitty, J. L., Skhinas, J. N., Filipe, E. C., Wang, S., Rodriquez Cupello, C., Grant, R. D., … Major, G., … Cox, T. R. (2020). The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development. Cancer Reports, 3(1), e1209. doi: 10.1002/cnr2.1209

Journal - Research Other

Elgundi, Z., Papanicolaou, M., Major, G., Cox, T. R., Melrose, J., Whitelock, J. M., & Farrugia, B. L. (2020). Cancer metastasis: The role of the extracellular matrix and the heparan sulfate proteoglycan perlecan. Frontiers in Oncology, 9, 1482. doi: 10.3389/fonc.2019.01482

Journal - Research Other

Longoni, A., Major, G., Atienza-Roca, P., Wise, L., Hooper, G., Kieser, D., Woodfield, T., … Lim, K. (2022). Gelatin incorporation in VEGF-loaded PVA-Tyramine hydrogels to enhance cellular interaction and vascular infiltration. Tissue Engineering Part A, 28(Suppl. 3), (pp. 642). doi: 10.1089/ten.tea.2022.29036.abstracts

Conference Contribution - Published proceedings: Abstract

Major, G., Longoni, A., Simcock, J., Lim, K., & Woodfield, T. (2022). Developing next generation adipose tissue grafts for soft tissue reconstruction. Tissue Engineering Part A, 28(Suppl. 3), (pp. 187). doi: 10.1089/ten.tea.2022.29036.abstracts

Conference Contribution - Published proceedings: Abstract

Major, G. (2022, April). Developing next generation adipose tissue grafts for soft tissue reconstruction. Keynote presentation at the Australasian Society for Biomaterials and Tissue Engineering (ASBTE) 27th annual Conference, Melbourne, Australia.

Conference Contribution - Verbal presentation and other Conference outputs

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