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Sir John Walsh Research Institute researcher profile

Dr Lara Friedlander

PositionSenior Lecturer Endodontics
DepartmentDepartment of Oral Rehabilitation
QualificationsBDS MDS PhD(Otago) FRACDS FICD
Research summaryEndodontics, practice-based research, dental education, immunopathology
Teaching
  • Chair, Final Year Dentistry
  • Course Co-ordinator Clinical Practice for General Dentistry
  • Clinical Co-ordinator of Clinical Doctorate in Endodontics
ClinicalSpecialist endodontics with particular interest in immature permanent teeth, vital pulp therapy and regeneration.

Research

Dr Lara Friedlander is a Specialist Endodontist with research in the areas of pulp development and disease, practice-based research, dental education and immunopathology. She is deputy director of the Immunopathology Research Group of the Sir John Walsh Research Institute.

Dr Friedlander has developed research themes in pulpal biology, regeneration and angiogenesis; and separate from this is also active in research related to Endodontic curriculum development and teaching.

Results of her PhD research around pulp biology and angiogenesis associated with immature permanent teeth have been presented at international conferences and published in internationally peer-reviewed journals. This work has influenced clinical practice by providing further knowledge about pulp cell behaviour and healing following dental trauma.

As main author she has published on Endodontic teaching and this work is on-going and now looking at 5 year outcomes. Dr Friedlander was invited to Switzerland to speak on endodontic curriculum development at the University Forum of 160 international universities and has been an invited international judge on a research panel.

Lara is a co-supervisor of Clinical Doctorate students and has PhD student supervision. She has had substantial competitive grant applications associated with these. Lara assists in advising on projects and funding applications including PhD pulp research which has evolved from her own research theme.

Dr Friedlander enjoys engaging with general dentists in practice-based research and is a member of the New Zealand Dental Research Foundation Board.

Additional details

Senior Examiner for Final examination for Fellowship with the Royal Australasian College of Dental Surgeons

Publications

Al-Hassiny, A., Hussani, H., Milne, T., Seo, B., Rich, A. M., & Friedlander, L. T. (2019). Vascularity and angiogenic signaling in the dentine-pulp complex of immature and mature permanent teeth. European Endodontic Journal, 4(2), 80-85. doi: 10.14744/eej.2019.26349

Friedlander, L. T., Meldrum, A. M., & Lyons, K. (2019). Curriculum development in final year dentistry to enhance competency and professionalism for contemporary general dental practice. European Journal of Dental Education. Advance online publication. doi: 10.1111/eje.12458

Al-Hassiny, A., Friedlander, L. T., Parachuru, V. P. B., Seo, B., Hussaini, H. M., & Rich, A. M. (2018). Upregulation of angiogenesis in oral lichen planus. Journal of Oral Pathology & Medicine, 47(2), 173-178. doi: 10.1111/jop.12665

Friedlander, L. T., Coates, D., Seymour, G., Cullinan, M., & Rich, A. M. (2018). Vascularity and VEGF/VEGFR2 signaling in the dentine–pulp complex of immature and mature permanent teeth. European Endodontic Journal, 3(3), 153-159. doi: 10.14744/eej.2018.07269

Russell, A. A., Chandler, N. P., & Friedlander, L. T. (2018). Crack formation following root-end preparation in roots with the butterfly effect. European Endodontic Journal, 3(2), 107-112. doi: 10.14744/eej.2018.47965

Journal - Research Article

Al-Hassiny, A., Hussani, H., Milne, T., Seo, B., Rich, A. M., & Friedlander, L. T. (2019). Vascularity and angiogenic signaling in the dentine-pulp complex of immature and mature permanent teeth. European Endodontic Journal, 4(2), 80-85. doi: 10.14744/eej.2019.26349

Friedlander, L. T., Meldrum, A. M., & Lyons, K. (2019). Curriculum development in final year dentistry to enhance competency and professionalism for contemporary general dental practice. European Journal of Dental Education. Advance online publication. doi: 10.1111/eje.12458

Al-Hassiny, A., Friedlander, L. T., Parachuru, V. P. B., Seo, B., Hussaini, H. M., & Rich, A. M. (2018). Upregulation of angiogenesis in oral lichen planus. Journal of Oral Pathology & Medicine, 47(2), 173-178. doi: 10.1111/jop.12665

Russell, A. A., Chandler, N. P., & Friedlander, L. T. (2018). Crack formation following root-end preparation in roots with the butterfly effect. European Endodontic Journal, 3(2), 107-112. doi: 10.14744/eej.2018.47965

Friedlander, L. T., Coates, D., Seymour, G., Cullinan, M., & Rich, A. M. (2018). Vascularity and VEGF/VEGFR2 signaling in the dentine–pulp complex of immature and mature permanent teeth. European Endodontic Journal, 3(3), 153-159. doi: 10.14744/eej.2018.07269

Russell, A., Friedlander, L., & Chandler, N. (2018). Sealer penetration and adaptation in root canals with the butterfly effect. Australian Endodontic Journal, 44(3), 225-234. doi: 10.1111/aej.12238

Russell, A. A., Chandler, N. P., & Friedlander, L. T. (2017). Vertical root fractures in root canal-treated teeth. ENDO, 11(3), 173-182.

Firth, F. A., Friedlander, L. T., Parachuru, V. P. B., Kardos, T. B., Seymour, G. J., & Rich, A. M. (2015). Regulation of immune cells in oral lichen planus. Archives of Dermatological Research, 307, 333-339. doi: 10.1007/s00403-015-1540-8

Friedlander, L. T., Hussaini, H., Cullinan, M. P., Seymour, G. J., De Silva, R. K., De Silva, H., Cameron, C., & Rich, A. M. (2015). VEGF and VEGFR2 in dentigerous cysts associated with impacted third molars. Pathology, 47(5), 446-451. doi: 10.1097/pat.0000000000000272

Friedlander, L., McElroy, K., Daniel, B., Cullinan, M., & Hanlin, S. (2015). Direct pulp capping of permanent teeth in New Zealand general dental practice: A practice based research study. New Zealand Dental Journal, 111(2), 58-64.

Alothmani, O. S., Friedlander, L. T., Monteith, B. D., & Chandler, N. P. (2013). Influence of clinical experience on the radiographic determination of endodontic working length. International Endodontic Journal, 46(3), 211-216. doi: 10.1111/j.1365-2591.2012.02109.x

Alothmani, O. S., Friedlander, L. T., & Chandler, N. P. (2013). Radiographic assessment of endodontic working length. Saudi Endodontic Journal, 3(2), 57-64. doi: 10.4103/1658-5984.118145

Alothmani, O. S., Chandler, N. P., & Friedlander, L. T. (2013). The anatomy of the root apex: A review and clinical considerations in endodontics. Saudi Endodontic Journal, 3(1), 1-9. doi: 10.4103/1658-5984.116273

Lin, Y. P., Love, R. M., Friedlander, L. T., Shang, H. F., & Pai, M. H. (2013). Expression of Toll-like receptor 2 and 4, and the OPG-RANKL-RANK system in inflammatory external root resorption and external cervical resorption. International Endodontic Journal, 46, 971-981. doi: 10.1111/iej.12088

Friedlander, L., & Anderson, V. (2011). A new predoctoral endodontic module: Evaluating learning and effectiveness. Journal of Dental Education, 75(3), 351-359.

Friedlander, L. T., Love, R. M., & Cullinan, M. P. (2009). Dental stem cells and their potential role in apexogenesis and apexification. International Endodontic Journal, 42(11), 955-962. doi: 10.1111/j.1365-2591.2009.01622.x

Buchanan, J., Colquhoun, A., Friedlander, L., Evans, S., Whitley, B., & Thomson, M. (2005). Maxillofacial fractures at Waikato Hospital, New Zealand: 1989 to 2000. New Zealand Medical Journal, 118(1217). Retrieved from http://journal.nzma.org.nz/journal/118-1217/1529/content.pdf

Friedlander, L. T., Love, R. M., & Chandler, N. P. (2002). A comparision of phosphor-plate digital images with conventional radiographs for the perceived clarity of fine endodontic files and periapical lesions. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 93, 321-327.

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Journal - Research Other

Friedlander, L. T., Chandler, N. P., & Drummond, B. K. (2013). Avulsion and replantation of a primary incisor tooth. Dental Traumatology, 29(6), 494-497. doi: 10.1111/j.1600-9657.2012.01168.x

Friedlander, L., Chandler, N., & Love, R. (2011). Periapical healing following combined non-surgical and surgical retreatments [Case report]. ENDO, 5(1), 27-34.

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