I am a Registered Nurse and Senior Research Fellow with the Wellington Asthma Research Group. Currently I am a co-investigator in the Maternal Probiotic Study (Studies of Probiotics and Allergic Disease). This is a randomized controlled trial clinical trial investigating the use of probiotics to prevent the development of allergic disease in infants, and reduce gestational diabetes and bacterial vaginal infections in pregnant women.
Research expertise and interest
My current research interest is in the field of allergic disease.
In the past four years I have worked on a series of quantitative studies related to both the prevention and treatment of allergic disease (eczema, hay fever and asthma).
Previous to this work my research interest and experience was in the area of oncology/palliative care using qualitative approaches to research.
Publications
Barthow, C., Kuiper, N., Betty, B., Viliamu-Amusia, I., Bryant, L., Ranchhod, D., … McKinlay, E., & Krebs, J. (2023). Seen and unseen work: The intensity of service provision for individuals with type 2 diabetes in a high-needs population [Research letter]. New Zealand Medical Journal/Te ara tika o te hauora hapori, 136(1581), 79-85. Retrieved from https://journal.nzma.org.nz/
Journal - Research Other
Williams, B., Ropati, J., Barthow, C., & McKinlay, E. (2023). Experiences of intergenerational diabetes in a Māori whānau and a Sāmoan aiga. Proceedings of the 46th New Zealand Society for the Study of Diabetes (NZSSD) Annual Scientific Meeting. Oral 16. Retrieved from https://www.nzssd.org.nz/home.html
Conference Contribution - Published proceedings: Abstract
Barthow, C., Krebs, J., & McKinlay, E. (2023). A multiple case study of pre-diabetes care undertaken by general practice in Aotearoa/New Zealand: De-incentivised and de-prioritised work. BMC Primary Care, 24, 109. doi: 10.1186/s12875-023-02053-1
Journal - Research Article
Barthow, C., Pullon, S., McKinlay, E., & Krebs, J. (2022). It is time for a more targeted approach to prediabetes in primary care in Aotearoa New Zealand. Journal of Primary Health Care, 14(4), 372-377. doi: 10.1071/HC22089
Journal - Research Other
Barthow, C., Pullon, S., Weatherall, M., & Krebs, J. (2022). They're sicker than we think: An exploratory study profiling the cardio-metabolic health in a sample of adults with pre-diabetes in Aotearoa New Zealand. Journal of Primary Health Care, 14(3), 221-228. doi: 10.1071/HC22068
Journal - Research Article
Barthow, C. A. (2022). Diabetes prevention amongst those with pre-diabetes in Aotearoa New Zealand (PhD). University of Otago, Dunedin, New Zealand. Retrieved from http://hdl.handle.net/10523/13597
Awarded Doctoral Degree
Parry Strong, A., Wright-McNaughton, M., Weatherall, M., Hall, R. M., Coppell, K. J., Barthow, C., & Krebs, J. D. (2022). Very low carbohydrate (ketogenic) diets in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials. Diabetes, Obesity & Metabolism, 24, 2431-2442. doi: 10.1111/dom.14837
Journal - Research Article
McKinlay, E., Hilder, J., Hood, F., Morgan, S., Barthow, C., Gray, B., Huthwaite, M., Weatherall, M., Crane, J., Krebs, J., & Pullon, S. (2022). Uncertainty and certainty: Perceptions and experiences of prediabetes in New Zealand primary care: A qualitative study. Journal of Primary Health Care, 14(2), 138-145. doi: 10.1071/HC21066
Journal - Research Article
Barthow, C., Pullon, S., Weatherall, M., & Krebs, J. (2022). They're sicker than we think: An exploratory study profiling the cardio-metabolic health of adults with pre-diabetes in Aotearoa New Zealand. Proceedings of the 45th New Zealand Society for the Study of Diabetes (NZSSD) Annual Scientific Meeting. (pp. 40). Retrieved from https://www.ivvy.com.au/event/NZSSD22/welcome.html
Conference Contribution - Published proceedings: Abstract
Parry Strong, A., Wright-McNaughton, M., Weatherall, M., Hall, R., Coppell, K., Barthow, C., & Krebs, J. (2022). Ketogenic compared to control diets in pre-diabetes and type 2 diabetes: A systematic review. Proceedings of the 45th New Zealand Society for the Study of Diabetes (NZSSD) Annual Scientific Meeting. (pp. 26). Retrieved from https://www.ivvy.com.au/event/NZSSD22/welcome.html
Conference Contribution - Published proceedings: Abstract
Barthow, C., Krebs, J., & McKinlay, E. (2022). Disincentivised and de-prioritised mahi: A Multiple case study of pre-diabetes care undertaken by
general practice in Aotearoa/New Zealand. Proceedings of the 45th New Zealand Society for the Study of Diabetes (NZSSD) Annual Scientific Meeting. (pp. 19). Retrieved from https://www.ivvy.com.au/event/NZSSD22/welcome.html
Conference Contribution - Published proceedings: Abstract
Barthow, C., Hood, F., Crane, J., Huthwaite, M., Weatherall, M., Parry-Strong, A., & Krebs, J. (2022). A randomised controlled trial of a probiotic and a prebiotic examining metabolic and mental health outcomes in adults with pre-diabetes. BMJ Open, 12, e055214. doi: 10.1136/bmjopen-2021-055214
Journal - Research Article
Barthow, C., Hood, F., Crane, J., Huthwaite, M., Weatherall, M., Parry-Strong, A., & Krebs, J. (2021). Can pro or pre-biotics prevent the progression of pre-diabetes? The effect of lactobaccilus rhamnosus hn001 and beta glucan on metabolic and mental health outcomes in adults with prediabetes: A randomized controlled trial. Proceedings of the 44th New Zealand Society for the Study of Diabetes (NZSSD) Annual Scientific Meeting. Retrieved from https://www.ivvy.com.au/event/NZSSD2021
Conference Contribution - Published proceedings: Abstract
Chen, Y., Lu, J., Wickens, K., Stanley, T., Maude, R. M., Stone, P., Barthow, C., Crane, J., … Murphy, R. (2021). Effect of Lactobacillus rhamnosus probiotic in early pregnancy on plasma conjugated bile acids in a randomised controlled trial. Nutrients, 13, 209. doi: 10.3390/nu13010209
Journal - Research Article
Crane, J., Barthow, C., Kang, J., Hood, F., Stanley, T., & Wickens, K. (2020). Probiotics for humans: Hoax, hype, hope, or help. Journal of the Royal Society of New Zealand, 50(3), 456-469. doi: 10.1080/03036758.2019.1692364
Journal - Research Other
Barthow, C., Hood, F., McKinlay, E., Hilder, J., Cleghorn, C., Huthwaite, M., Weatherall, M., Parry-Strong, A., Pullon, S., Gray, B., Wickens, K., Crane, J., & Krebs, J. (2019). Food 4 Health: He Oranga Kai: Assessing the efficacy, acceptability and economic implications of Lactobacillus rhamnosus HN001 and β-glucan to improve glycated haemoglobin, metabolic health, and general well-being in adults with pre-diabetes: Study protocol for a 2 x 2 factorial design, parallel group, placebo-controlled randomized controlled trial, with embedded qualitative study and economic analysis. Trials, 20, 464. doi: 10.1186/s13063-019-3553-7
Journal - Research Other
Slykerman, R. F., Coomarasamy, C., Wickens, K., Thompson, J. M. D., Stanley, T. V., Barthow, C., Kang, J., Crane, J., & Mitchell, E. A. (2019). Exposure to antibiotics in the first 24 months of life and neurocognitive outcomes at 11 years of age. Psychopharmacology, 236, 1573-1582. doi: 10.1007/s00213-019-05216-0
Journal - Research Article
Murphy, R., Morgan, X. C., Wang, X. Y., Wickens, K., Purdie, G., Fitzharris, P., Otal, A., Lawley, B., Stanley, T., Barthow, C., Crane, J., … Tannock, G. W. (2019). Eczema-protective probiotic alters infant gut microbiome functional capacity but not composition: Sub-sample analysis from a RCT. Beneficial Microbes, 10(1), 5-17. doi: 10.3920/bm2017.0191
Journal - Research Article
Pullon, S., Ballantyne, A., Macdonald, L., Barthow, C., Wickens, K., & Crane, J. (2019). Daily decision-making about food during pregnancy: A New Zealand study. Health Promotion International, 34(3), 469-478. doi: 10.1093/heapro/dax098
Journal - Research Article
Wickens, K., Barthow, C., Mitchell, E. A., Kang, J., Van Zyl, N., Purdie, G., Stanley, T., … Crane, J. (2018). Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 years. Pediatric Allergy & Immunology, 29, 808-814. doi: 10.1111/pai.12982
Journal - Research Article
Slykerman, R. F., Kang, J., Van Zyl, N., Barthow, C., Wickens, K., Stanley, T., … Purdie, G., … Crane, J., & Mitchell, E. A. (2018). Effect of early probiotic supplementation on childhood cognition, behaviour and mood a randomised, placebo-controlled trial. Acta Paediatrica, 107, 2172-2178. doi: 10.1111/apa.14590
Journal - Research Article
Crane, J., Barthow, C., Mitchell, E. A., Stanley, T. V., Purdie, G., Rowden, J., Kang, J., Hood, F., Barnes, P., … Wickens, K. (2018). Is yoghurt an acceptable alternative to raw milk for reducing eczema and allergy in infancy? Clinical & Experimental Allergy, 48(5), 604-606. doi: 10.1111/cea.13121
Journal - Research Other
Wickens, K., Barthow, C., Mitchell, E. A., Stanley, T. V., Purdie, G., Rowden, J., Kang, J., Hood, F., … Franklin, I., Barnes, P., … Abels, P., … Crane, J. (2018). Maternal supplementation alone with Lactobacillus rhamnosus HN001 during pregnancy and breastfeeding does not reduce infant eczema. Pediatric Allergy & Immunology, 29(3), 296-302. doi: 10.1111/pai.12874
Journal - Research Article
Slykerman, R., Hood, F., Wickens, K., Thompson, J., Barthow, C., Murphy, R., Kang, J., … Crane, J., Stanley, T., Abels, P., Purdie, G., … Mitchell, E. (2017, November). Effect of lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: A randomised double-blind placebo-controlled trial. Verbal presentation at the Paediatric Society of New Zealand 69th Annual Scientific Meeting, Christchurch, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
McKinlay, E., Gallagher, P., Jones, B., Macdonald, L., & Barthow, C. (2017). Crossing professional cultures: A qualitative study of nurses working in a medical school. Contemporary Nurse, 53(6), 633-646. doi: 10.1080/10376178.2017.1416304
Journal - Research Article
Slykerman, R. F., Hood, F., Wickens, K., Thompson, J. M. D., Barthow, C., Murphy, R., Kang, J., … Crane, J., Stanley, T., Abels, P., Purdie, G., … the Probiotic in Pregnancy Study Group. (2017). Effect of Lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: A randomised double-blind placebo-controlled trial. EBioMedicine, 24, 159-165. doi: 10.1016/j.ebiom.2017.09.013
Journal - Research Article
Ballantyne, A., Pullon, S., Macdonald, L., Barthow, C., Wickens, K., & Crane, J. (2017). The experiences of pregnant women in an interventional clinical trial: Research in Pregnancy Ethics (RIPE) study. Bioethics, 31(6), 476-483. doi: 10.1111/bioe.12361
Journal - Research Article
Wickens, K. L., Barthow, C. A., Murphy, R., Abels, P. R., Maude, R. M., Stone, P. R., … Stanley, T. V., Purdie, G. L., Kang, J. M., Hood, F. E., … Barnes, P. K., … Crane, J. (2017). Early pregnancy probiotic supplementation with Lactobacillus rhamnosus HN001 may reduce the prevalence of gestational diabetes mellitus: A randomised controlled trial. British Journal of Nutrition, 117(6), 804-813. doi: 10.1017/S0007114517000289
Journal - Research Article
Hood, F., Wickens, K., Barthow, C., Maude, R., Murphy, R., Abels, P., … Stanley, T., Kang, J., … Purdie, G., & Crane, J. (2016, August). Can early pregnancy probiotic supplementation reduce the rate of gestational diabetes? Verbal presentation at the 14th New Zealand College of Midwives Biennial National Conference, Auckland, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Ballantyne, A., Barthow, C., & Wickens, K. (2016). Research into lifestyle changes in pregnancy. In F. Baylis & A. Ballantyne (Eds.), Clinical research involving pregnant women. (pp. 211-225). Springer. doi: 10.1007/978-3-319-26512-4_12
Chapter in Book - Research
Maude, R., Wickens, K., Barthow, C., Murphy, R., Abels, P., Stone, P., … Stanley, T., Purdie, G., Kang, J., Hood, F., … Barnes, P., … Crane, J. (2016, October). Can early pregnancy probiotic supplementation reduce the rate of gestational diabetes? Poster session presented at the 11th International Normal Labour and Birth Conference (NLBC), Sydney, Australia.
Conference Contribution - Poster Presentation (not in published proceedings)
Barthow, C., Wickens, K., Stanley, T., Mitchell, E. A., Maude, R., Abels, P., Purdie, G., … Kang, J., Hood, F., … Barnes, P., Fitzharris, P., … Crane, J. (2016). The Probiotics in Pregnancy Study (PiP Study): Rationale and design of a double-blind randomised controlled trial to improve maternal health during pregnancy and prevent infant eczema and allergy. BMC Pregnancy & Childbirth, 16, 133. doi: 10.1186/s12884-016-0923-y
Journal - Research Other
Wickens, K., Barthow, C., Murphy, R., Abels, P., Stone, P., Mitchell, E., … Stanley, T., … Kang, J., Hood, F., Fitzharris, P., & Crane, J. (2015, April). Can early pregnancy probiotic supplementation reduce gestational diabetes incidence? Poster session presented at the Developmental Origins of Health & Disease (DOHaD) Society of Australia & New Zealand Conference: A Healthy Start for the Human Race, Melbourne, Australia.
Conference Contribution - Poster Presentation (not in published proceedings)
Barthow, C., Wickens, K., Murphy, R., Abels, P., Stone, P., Mitchell, E., … Stanley, T., Kang, J., Hood, F., Fitzharris, P., Purdie, G., & Crane, J. (2015, June-July). Can early pregnancy probiotic supplementation reduce the rate of gestational diabetes? Verbal presentation at the UK Probiotics Conference, Egham, UK.
Conference Contribution - Verbal presentation and other Conference outputs
Marlow, G., Han, D. Y., Wickens, K., Stanley, T., Crane, J., Mitchell, E. A., … Barthow, C., … Morgan, A. R. (2015). Differential effects of two probiotics on the risks of eczema and atopy associated with single nucleotide polymorphisms to Toll-like receptors. Pediatric Allergy & Immunology, 26(3), 262-271. doi: 10.1111/pai.12371
Journal - Research Article
Barthow, C., Jones, B., Macdonald, L., Vernall, S., Gallagher, P., & McKinlay, E. (2015). Researching in the community: The value and contribution of nurses to community based or primary health care research. Primary Health Care Research & Development, 16, 224-234. doi: 10.1017/s1463423614000097
Journal - Research Article
Wickens, K., Stanley, T., Mitchell, E., Barthow, C., Fitzharris, P., Purdie, G., Siebers, R., … Crane, J. (2014). Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: Does it also reduce atopic sensitization? Clinical & Translational Allergy, 4(Suppl. 1), O9. doi: 10.1186/2045-7022-4-S1-O9
Conference Contribution - Published proceedings: Abstract
Siebers, R., Wickens, K., Stanley, T., Barthow, C., Mitchell, E. A., Fitzharris, P., … Crane, J. (2014). Increased serum thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) levels in 6 year-old children with eczema are related to disease severity. Allergy, 69(Suppl. 99), (pp. 218). doi: 10.1111/all.12476
Conference Contribution - Published proceedings: Abstract
Morgan, A. R., Han, D. Y., Wickens, K., Barthow, C., Mitchell, E. A., Stanley, T. V., Dekker, J., Crane, J., & Ferguson, L. R. (2014). Differential modification of genetic susceptibility to childhood eczema by two probiotics. Clinical & Experimental Allergy, 44(10), 1255-1265. doi: 10.1111/cea.12394
Journal - Research Article
Wickens, K., Stanley, T. V., Mitchell, E. A., Barthow, C., Fitzharris, P., Purdie, G., Siebers, R., … Crane, J. (2013). Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: Does it also reduce atopic sensitization? Clinical & Experimental Allergy, 43(9), 1048-1057. doi: 10.1111/cea.12154
Journal - Research Article
Barthow, C., Jones, B., Macdonald, L., Vernall, S., Gallagher, P., & McKinlay, E. (2012, November). Research nurses in community based research: Transferring evidence of effectiveness. Verbal presentation at the New Zealand Nurses Organisation (NZNO) Nursing Research Section Conference, Nelson, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Wickens, K., Black, P., Stanley, T. V., Mitchell, E., Barthow, C., Fitzharris, P., Purdie, G., & Crane, J. (2012). A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clinical & Experimental Allergy, 42(7), 1071-1079. doi: 10.1111/j.1365-2222.2012.03975.x
Journal - Research Article
Barthow, C., Wickens, K., Ingham, T., Swanney, M., Stanton, J., Lampshire, P., Town, I., Epton, M., Pattemore, P., Crane, J., and the New Zealand Asthma and Allergy Cohort Study Group. (2011). Spirometry quality control and ability to predict asthma in 6 yr old children. Proceedings of the Annual Scientific Meetings of The Thoracic Society of Australia and New Zealand (TSANZ) & The Australian and New Zealand Society of Respiratory Science (ANZSRS). TP-004. Retrieved from http://www.fcconventions.com.au/TSANZ2011/08.pdf
Conference Contribution - Published proceedings: Abstract
Barthow, C., Wickens, K., Ingham, T., Swanney, M., Stanton, J., Lampshire, P., Town, I., Epton, M., Pattemore, P., Crane, J., The New Zealand Asthma and Allergy Cohort Study Group. (2011). Spirometry quality control and ability to predict asthma in 6-year-old children. Respirology, 16(Suppl. 1), (pp. 37). doi: 10.1111/j.1440-1843.2011.01937_1.x
Conference Contribution - Published proceedings: Abstract
Wickens, K., Black, P., Stanley, T., Mitchell, E., Barthow, C., Fitzharris, P., Purdie, G., & Crane, J. (2011). A differential effect of 2 probiotics on allergic disease to age 4 years. Journal of Allergy and Clinical Immunology.127(2, Suppl. 1), (pp. AB38). doi: 10.1016/j.jaci.2010.12.160
Conference Contribution - Published proceedings: Abstract
Crane, J., Wickens, K., Stanley, T., Mitchell, E., Barthow, C., Fitzharris, P., & Black, P. (2010). Staphylococcal colonisation and atopy. Internal Medicine Journal.40(Suppl. 4), (pp. 6). doi: 10.1111/j.1445-5994.2010.02322.x
Conference Contribution - Published proceedings: Abstract
Wickens, K., Black, P., Stanley, T. V., Mitchell, E., Barthow, C., Purdie, G., Fitzharris, P., & Crane, J. (2010). A differential effect of 2 probiotics on allergic disease to age 4 years. Internal Medicine Journal.40(Suppl. 4), (pp. 19-20). doi: 10.1111/j.1445-5994.2010.02322.x
Conference Contribution - Published proceedings: Abstract
McCullough, L., McKinlay, E., Barthow, C., Moss, C., & Wise, D. (2010). A model of treatment decision making when patients have advanced cancer: How do cancer treatment doctors and nurses contribute to the process? European Journal of Cancer Care, 19(4), 482-491. doi: 10.1111/j.1365-2354.2009.01074.x
Journal - Research Article
Barthow, C. & Jones, B. (May, 2009). Probiotic study: A study to prevent eczema & allergy in children. Otago Wellington Nurses Network, Wellington, New Zealand. [Research Presentation].
Other Research Output
Barthow, C., Moss, C., McKinlay, E., McCullough, L., & Wise, D. (2009). To be involved or not: Factors that influence nurses' involvement in providing treatment decisional support in advanced cancer. European Journal of Oncology Nursing, 13(1), 22-28. doi: 10.1016/j.ejon.2008.09.004
Journal - Research Article
McCullough, L., McKinlay, E., Barthow, C., Wise, D., & Moss, C. (2005). Exploring clinician decision-making in advanced cancer treatment. Proceedings of the 13th National Haematology & Oncology Nurses Conference [Abstracts]. (A4). [Abstract]
Conference Contribution - Published proceedings: Abstract
Barthow, C., Moss, C., McCullough, L., McKinlay, E., & Wise, D. (2005). Nurses roles in decision-making regarding the use of anticancer therapy in advanced disease. Proceedings of the National 13th Haematology & Oncology Nurses Conference [Abstracts]. (A17). [Abstract]
Conference Contribution - Published proceedings: Abstract
McCullough, L., Barthow, C., McKinlay, E., Wise, D., & Moss, C. (2004, August). Decision-making in advanced cancer treatment. Poster session presented at the 13th International Conference on Cancer Nursing, Sydney, Australia.
Conference Contribution - Poster Presentation (not in published proceedings)