Associate Professor Shieak YC Tzeng, Department of Surgery and Anaesthesia

Journal - Research Article

Fan, J.-L., O'Donnell, T., Lanford, J., Croft, K., Watson, E., Smyth, D., … Tzeng, Y.-C. (2020). Dietary nitrate reduces blood pressure and cerebral artery velocity fluctuations and improve cerebral autoregulation in transient ischemic attack patients. Journal of Applied Physiology. Advance online publication. doi: 10.1152/japplphysiol.00160.2020

Fan, J.-L., O'Donnell, T., Gray, C. L., Croft, K., Noakes, A. K., Koch, H., & Tzeng, Y.-C. (2019). Dietary nitrate supplementation enhances cerebrovascular CO₂ reactivity in a sex-specific manner. Journal of Applied Physiology, 127, 760-769. doi: 10.1152/japplphysiol.01116.2018

Allan, P. D., O'Donnell, T., & Tzeng, Y.-C. (2018). Agreement between finger plethysmography- and brachial oscillometry-derived blood pressure measurements. Clinical Physiology & Functional Imaging, 38(3), 439-446. doi: 10.1111/cpf.12435

Allan, P. D., Tzeng, Y.-C., Gowing, E. K., Clarkson, A. N., & Fan, J.-L. (2018). Dietary nitrate supplementation reduces low frequency blood pressure fluctuations in rats following distal middle cerebral artery occlusion. Journal of Applied Physiology, 125(3), 862-869. doi: 10.1152/japplphysiol.01081.2017

Saleem, S., Vucina, D., Sarafis, Z., Lee, A. H. X., Squair, J. W., Barak, O. F., … Tzeng, Y.-C., & Phillips, A. A. (2018). Wavelet decomposition analysis is a clinically relevant strategy to evaluate cerebrovascular buffering of blood pressure after spinal cord injury. American Journal of Physiology: Heart & Circulatory Physiology, 314(5), H1108-H1114. doi: 10.1152/ajpheart.00152.2017

Saleem, S., Teal, P. D., Howe, C. A., Tymko, M. M., Ainslie, P. N., & Tzeng, Y.-C. (2018). Is Cushing mechanism a dynamic blood pressure stabilizing system? Insights from Granger causality analysis of spontaneous blood pressure and cerebral blood flow. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 315(3), R484-R495. doi: 10.1152/ajpregu.00032.2018

Malenfant, S., Brassard, P., Paquette, M., Le Blanc, O., Chouinard, A., Nadeau, V., Allan, P. D., Tzeng, Y.-C., … Provencher, S. (2017). Compromised cerebrovascular regulation and cerebral oxygenation in pulmonary arterial hypertension. Journal of the American Heart Association, 6(10), e006126. doi: 10.1161/jaha.117.006126

Faulkner, J., Tzeng, Y.-C., Lambrick, D., Woolley, B., Allan, P. D., O'Donnell, T., Lanford, J., Wong, L., & Stoner, L. (2017). A randomized controlled trial to assess the central hemodynamic response to exercise in patients with transient ischaemic attack and minor stroke. Journal of Human Hypertension, 31, 172-177. doi: 10.1038/jhh.2016.72

Phillips, A. A., Squair, J., Currie, K., Tzeng, Y.-C., Ainslie, P., & Krassioukov, A. V. (2017). 2015 ParaPan American Games: Autonomic function, but not physical activity, is associated with vascular-cognitive impairment in spinal cord injury. Journal of Neurotrauma, 34(6), 1283-1288. doi: 10.1089/neu.2016.4751

Saleem, S., Tzeng, Y.-C., Kleijn, W. B., & Teal, P. D. (2017). Detection of impaired sympathetic cerebrovascular control using functional biomarkers based on principal dynamic mode analysis. Frontiers in Physiology, 7, 685. doi: 10.3389/fphys.2016.00685

Witter, T., Tzeng, Y.-C., O'Donnell, T., Kusel, J., Walker, B., Berry, M., & Taylor, C. E. (2017). Inter-individual relationships between sympathetic arterial baroreflex function and cerebral perfusion control in healthy males. Frontiers in Neuroscience, 11, 457. doi: 10.3389/fnins.2017.00457

Saleem, S., Teal, P. D., Kleijn, W. B., Ainslie, P. N., & Tzeng, Y.-C. (2016). Identification of human sympathetic neurovascular control using multivariate wavelet decomposition analysis. American Journal of Physiology: Heart & Circulatory Physiology, 311(3), H837-H848. doi: 10.1152/ajpheart.00254.2016

Smirl, J. D., Hoffman, K., Tzeng, Y.-C., Hansen, A., & Ainslie, P. N. (2016). The relationship between blood pressure and cerebral blood flow during supine cycling: Influence of aging. Journal of Applied Physiology, 120(5), 552-563. doi: 10.1152/japplphysiol.00667.2015

Saleem, S., Teal, P. D., Kleijn, W. B., O'Donnell, T., Witter, T., & Tzeng, Y.-C. (2015). Non-linear characterisation of cerebral pressure-flow dynamics in humans. PLoS ONE, 10(9), e0139470. doi: 10.1371/journal.pone.0139470

Horsman, H. M., Peebles, K. C., & Tzeng, Y. C. (2015). Interactions between breathing rate and low-frequency fluctuations in blood pressure and cardiac intervals. Journal of Applied Physiology, 119, 793-798. doi: 10.1152/japplphysiol.00525.2015

Rickards, C. A., Sprick, J. D., Colby, H. B., Kay, V., & Tzeng, Y.-C. (2015). Coupling between arterial pressure, cerebral blood velocity, and cerebral tissue oxygenation with spontaneous and forced oscillations. Physiological Measurement, 36(4), 785-801. doi: 10.1088/0967-3334/36/4/785

Smirl, J. D., Hoffman, K., Tzeng, Y.-C., Hansen, A., & Ainslie, P. N. (2015). Methodological comparison of active- and passive-driven oscillations in blood pressure: Implications for the assessment of cerebral pressure-flow relationships. Journal of Applied Physiology, 119(5), 487-501. doi: 10.1152/japplphysiol.00264.2015

Allan, P. D., Faulkner, J., O'Donnell, T., Lanford, J., Wong, L., Saleem, S., … Tzeng, Y.-C. (2015). Hemodynamic variability and cerebrovascular control after transient cerebral ischemia. Physiological Reports, 3(11), e12602. doi: 10.14814/phy2.12602

Rickards, C. A., & Tzeng, Y.-C. (2014). Arterial pressure and cerebral blood flow variability: Friend or foe? A review. Frontiers in Physiology, 5, 120. doi: 10.3389/fphys.2014.00120

Meel-van den Abeelen, A. S. S., Simpson, D. M., Wang, L. J. Y., Slump, C. H., Zhang, R., Tarumi, T., … Tzeng, Y.-C., … Claassen, J. A. H. R. (2014). Between-centre variability in transfer function analysis, a widely used method for linear quantification of the dynamic pressure-flow relation: The CARNet study. Medical Engineering & Physics, 36(5), 620-627. doi: 10.1016/j.medengphy.2014.02.002

Horsman, H. M., Tzeng, Y. C., Galletly, D. C., & Peebles, K. C. (2014). The repeated sit-to-stand manoeuvre is a superior method for cardiac baroreflex assessment: A comparison with the modified Oxford method and Valsalva manoeuvre. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 307(11), R1345-R1352. doi: 10.1152/ajpregu.00376.2014

Smirl, J. D., Tzeng, Y. C., Monteleone, B. J., & Ainslie, P. N. (2014). Influence of cerebrovascular resistance on the dynamic relationship between blood pressure and cerebral blood flow in humans. Journal of Applied Physiology, 116(12), 1614-1622. doi: 10.1152/japplphysiol.01266.2013

Berry, M., Tzeng, Y., & Marsland, C. (2014). Percutaneous transtracheal ventilation in an obstructed airway model in post-apnoeic sheep. British Journal of Anaesthesia, 113(6), 1039-1045. doi: 10.1093/bja/aeu188

Tzeng, Y.-C., & Ainslie, P. N. (2014). Blood pressure regulation IX: Cerebral autoregulation under blood pressure challenges. European Journal of Applied Physiology, 114(3), 545-559. doi: 10.1007/s00421-013-2667-y

Smirl, J. D., Haykowsky, M. J., Nelson, M. D., Tzeng, Y.-C., Marsden, K. R., Jones, H., & Ainslie, P. N. (2014). Relationship between cerebral blood flow and blood pressure in long-term heart transplant recipients. Hypertension, 64, 1314-1320. doi: 10.1161/hypertensionaha.114.04236

Tzeng, Y. C., MacRae, B. A., Ainslie, P. N., & Chan, G. S. H. (2014). Fundamental relationships between blood pressure and cerebral blood flow in humans. Journal of Applied Physiology, 117(9), 1037-1048. doi: 10.1152/japplphysiol.00366.2014

Willie, C. K., Tzeng, Y.-C., Fisher, J. A., & Ainslie, P. N. (2014). Integrative regulation of human brain blood flow. Journal of Physiology, 592(5), 841-859. doi: 10.1113/jphysiol.2013.268953

Taylor, C. E., Willie, C. K., Ainslie, P. N., & Tzeng, Y.-C. (2014). Assessment of human baroreflex function using carotid ultrasonography: What have we learnt? Acta Physiologica, 211(2), 297-313. doi: 10.1111/apha.12302

Taylor, C. E., Willie, C. K., Atkinson, G., Jones, H., & Tzeng, Y.-C. (2013). Postural influences on the mechanical and neural components of the cardiovagal baroreflex. Acta Physiologica, 208(1), 66-73. doi: 10.1111/apha.12087

Horsman, H. M., Peebles, K. C., Galletly, D. C., & Tzeng, Y.-C. (2013). Cardiac baroreflex gain is frequency dependent: Insights from repeated sit-to-stand maneuvers and the modified Oxford Method. Applied Physiology, Nutrition, & Metabolism, 38(7), 753-759. doi: 10.1139/apnm-2012-0444

Peebles, K. C., Horsman, H., & Tzeng, Y.-C. (2013). The influence of tobacco smoking on the relationship between pressure and flow in the middle cerebral artery in humans. PLoS ONE, 8(8), e72624. doi: 10.1371/journal.pone.0072624

Tan, C. O., Tzeng, Y.-C., Hamner, J. W., Tamisier, R., & Taylor, J. A. (2013). Alterations in sympathetic neurovascular transduction during acute hypoxia in humans. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 304(11), R959-R965. doi: 10.1152/ajpregu.00071.2013

Tzeng, Y.-C., & MacRae, B. A. (2013). Interindividual relationships between blood pressure and cerebral blood flow variability with intact and blunted cerebrovascular control. Journal of Applied Physiology, 114(7), 888-895. doi: 10.1152/japplphysiol.01388.2012

Willie, C. K., Ainslie, P. N., Taylor, C. E., Eves, N. D., & Tzeng, Y.-C. (2013). Maintained cerebrovascular function during post-exercise hypotension. European Journal of Applied Physiology, 113(6), 1597-1604. doi: 10.1007/s00421-012-2578-3

Peebles, K. C., Ball, O. G., MacRae, B. A., Horsman, H. M., & Tzeng, Y. C. (2012). Sympathetic regulation of the human cerebrovascular response to carbon dioxide. Journal of Applied Physiology, 113(5), 700-706. doi: 10.1152/japplphysiol.00614.2012

Gelinas, J. C., Marsden, K. R., Tzeng, Y. C., Smirl, J. D., Smith, K. J., Willie, C. K., … Ainslie, P. N. (2012). Influence of posture on the regulation of cerebral perfusion. Aviation, Space, & Environmental Medicine, 83(8), 751-757. doi: 10.3357/asem.3269.2012

Marsden, K. R., Haykowsky, M. J., Smirl, J. D., Jones, H., Nelson, M. D., Altamirano-Diaz, L. A., … Tzeng, Y. C., … Ainslie, P. N. (2012). Aging blunts hyperventilation-induced hypocapnia and reduction in cerebral blood flow velocity during maximal exercise. Age, 34(3), 725-735. doi: 10.1007/s11357-011-9258-9

Tzeng, Y. C., Ainslie, P. N., Cooke, W. H., Peebles, K. C., Willie, C. K., MacRae, B. A., … Horsman, H. M., & Rickards, C. A. (2012). Assessment of cerebral autoregulation: The quandary of quantification. American Journal of Physiology: Heart & Circulatory Physiology, 303(6), H658-H671. doi: 10.1152/ajpheart.00328.2012

Willie, C. K., Macleod, D. B., Shaw, A. D., Smith, K. J., Tzeng, Y. C., Eves, N. D., … Ainslie, P. N. (2012). Regional brain blood flow in man during acute changes in arterial blood gases. Journal of Physiology, 590(14), 3261-3275. doi: 10.1113/jphysiol.2012.228551

Ainslie, P. N., Lucas, S. J. E., Fan, J.-L., Thomas, K. N., Cotter, J. D., Tzeng, Y. C., & Burgess, K. R. (2012). Influence of sympathoexcitation at high altitude on cerebrovascular function and ventilatory control in humans. Journal of Applied Physiology, 113(7), 1058-1067. doi: 10.1152/japplphysiol.00463.2012

Sin, P. Y. W., Webber, M. R., Galletly, D. C., & Tzeng, Y. C. (2012). Relationship between cardioventilatory coupling and pulmonary gas exchange. Clinical Physiology & Functional Imaging, 32(6), 476-480. doi: 10.1111/j.1475-097X.2012.01144.x

Hamner, J. W., Tan, C. O., Tzeng, Y.-C., & Taylor, J. A. (2012). Cholinergic control of the cerebral vasculature in humans. Journal of Physiology, 590(24), 6343-6352. doi: 10.1113/jphysiol.2012.245100

Tzeng, Y.-C., & Chan, G. S. H. (2011). Unraveling the human cerebral circulation: Insights from cerebral blood pressure and flow recordings. Journal of Applied Physiology, 111(2), 349-350. doi: 10.1152/japplphysiol.00715.2011

Willie, C. K., Ainslie, P. N., Taylor, C. E., Jones, H., Sin, P. Y. W., & Tzeng, Y.-C. (2011). Neuromechanical features of the cardiac baroreflex after exercise. Hypertension, 57, 927-933. doi: 10.1161/HYPERTENSIONAHA.110.164616

Chan, G. S. H., Ainslie, P. N., Willie, C. K., Taylor, C. E., Atkinson, G., Jones, H., … Tzeng, Y.-C. (2011). Contribution of arterial Windkessel in low-frequency cerebral hemodynamics during transient changes in blood pressure. Journal of Applied Physiology, 110(4), 917-925. doi: 10.1152/japplphysiol.01407.2010

Bellapart, J., Chan, G. S., Tzeng, Y.-C., Ainslie, P., Barnett, A. G., Dunster, K. R., … Fraser, J. F. (2011). The effect of Ventricular Assist Devices on cerebral autoregulation: A preliminary study. BMC Anesthesiology, 11, 4. doi: 10.1186/1471-2253-11-4

Lewis, N. C. S., Atkinson, G., Lucas, S. J. E., Grant, E. J. M., Jones, H., Tzeng, Y. C., Horsman, H., & Ainslie, P. N. (2011). Is there diurnal variation in initial and delayed orthostatic hypotension during standing and head-up tilt? Chronobiology International, 28(2), 135-145. doi: 10.3109/07420528.2010.536283

Bellapart, J., Chan, G. S. H., Tzeng, Y.-C., Ainslie, P. N., Dunster, K. R., Barnett, A. G., … Fraser, J. F. (2011). The effect of ventricular assist devices on cerebral blood flow and blood pressure fractality. Physiological Measurement, 32(9), 1361-1372. doi: 10.1088/0967-3334/32/9/001

Atkinson, G., Batterham, A. M., Jones, H., Taylor, C. E., Willie, C. K., & Tzeng, Y.-C. (2011). Appropriate within-subjects statistical models for the analysis of baroreflex sensitivity. Clinical Physiology & Functional Imaging, 31(1), 80-82. doi: 10.1111/j.1475-097X.2010.00974.x

Willie, C. K., Colino, F. L., Bailey, D. M., Tzeng, Y. C., Binsted, G., Jones, L. W., … Lucas, S. J., … Ainslie, P. N. (2011). Utility of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function. Journal of Neuroscience Methods, 196(2), 221-237. doi: 10.1016/j.jneumeth.2011.01.011