Professor Ian Morison
MB ChB, BMedSc, PhD, FRCPA(Haem)Professor Ian Morison is a research haematologist at the University of Otago.
Ian's research interests are focused around genetic and epigenetic aspects of haematology and blood cancers, as well as the role of epigenetics in development. His work includes: studying childhood acute lymphoblastic leukaemia and its molecular origins; studying the epigenetics of myelodysplastic syndrome; identifying epigenetic differences between individuals; and the biochemical mechanisms behind familial thrombocytopenia.
After graduating from Otago with a medical degree, Ian took up a residency in clinical pathology at the University of Washington. It was during this time that he recognised the potential for research in all areas of pathology and laboratory medicine. In the years since, he has built a career as both a diagnostic haematologist and a researcher, maximising the synergies between the two.
Publications
Adriaansen, M. J., Morison, I. M., & Perry, H. E. (2024). Discrepancies between two D-dimer assays and impact on clinical decisions: A retrospective analysis of samples tested in community- and hospital-based laboratories in Auckland. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1589), 12-19. Retrieved from https://nzmj.org.nz/ Journal - Research Article
Powell, R. M., Moravec, J. C., Jones, G. T., Bhat, B., Lin, S. M., Planer, J. D., … Pattison, S., Morison, I. M., … Eccles, M. R., & Macaulay, E. C. (2024). DNA methylation profiling of heterogeneous sporadic LAM and matched lung tissue. American Journal of Respiratory Cell & Molecular Biology, 70(1), 81-84. doi: 10.1165/rcmb.2023-0300LE Journal - Research Other
Ronayne, C., Morison, I., & Hancox, B. (2023). Looking through the lipid glass: Is everything as it seems? In T. Milne, M. Anwar, L. Burga, H. Harcombe, M. Garelja, A. Middleton, D. C. Ribeiro, N. Fleming, K. Ogbuehi & A. Bahn (Eds.), Proceedings of the 266th Otago Medical School Research Society (OMSRS) Meeting: Research Staff Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839 Conference Contribution - Published proceedings: Abstract
Dunnet, M. J., Ortega-Recalde, O. J., Waters, S. A., Weeks, R. J., Morison, I. M., & Hore, T. A. (2022). Leukocyte-specific DNA methylation biomarkers and their implication for pathological epigenetic analysis. Epigenetics Communications, 2, 5. doi: 10.1186/s43682-022-00011-z Journal - Research Article
Dunnet, M. J., Ortega-Recalde, O. J., Waters, S. A., Weeks, R. J., Morison, I. M., & Hore, T. A. (2022, August). Cell-specific DNA methylation patterns of leukocytes and their implication for epigenetic analyses of health and disease. Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Ravichandran, M., Rafalski, D., Davies, C. I., Ortega-Recalde, O., Nan, X., Glanfield, C. R., … Mayyas, I. M., Kardailsky, O., … Morison, I. M., Hore, T. A., & Jurkowski, T. P. (2022). Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function. Science Advances, 8, eabm2427. doi: 10.1126/sciadv.abm2427 Journal - Research Article
Powell, R. M., Pattison, S., Moravec, J. C., Bhat, B., Guirguis, N., Markie, D., Jones, G. T., … Print, C. G., Morison, I. M., Gavryushkin, A., … Eccles, M. R., & Macaulay, E. C. (2022). Tuberous sclerosis complex: A complex case. Molecular Case Studies, 8, a006182. doi: 10.1101/mcs.a006182 Journal - Research Article
Dunstan-Harrison, C., Morison, I. M., & Ledgerwood, E. C. (2022). A novel frameshift GP1BB mutation causes autosomal dominant macrothrombocytopenia with decreased vWF receptor expression but normal platelet aggregation. Platelets, 33(2), 324-327. doi: 10.1080/09537104.2021.1909716 Journal - Research Other
Dunstan-Harrison, C., Ledgerwood, E., & Morison, I. (2021). Determining the molecular and functional basis of inherited thrombocytopenia in New Zealand families. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 280). Retrieved from https://www.faobmb2021.org Conference Contribution - Published proceedings: Abstract
Davies, C. I., Wang, A. H., Kardailsky, O., Morison, I., & Hore, T. A. (2021). Exploring the role of ZNF595 in Wilms tumour. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 52). Retrieved from https://www.faobmb2021.org Conference Contribution - Published proceedings: Abstract
Dunnet, M. J., Bond, D. M., Waters, S. A., Morison, I. M., & Hore, T. A. (2021). Cell-specific DNA methylation patterns of leukocytes and their implications for epigenetic analyses of health and disease. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 81). Retrieved from https://www.faobmb2021.org Conference Contribution - Published proceedings: Abstract
Dunnet, M. J., Bond, D. M., Waters, S. A., Morison, I. M., & Hore, T. A. (2021). Cell-specific DNA methylation patterns of leukocytes and their implication for epigenetic analyses of health and disease. Proceedings of the Genetics Otago (GO) Annual Symposium. Retrieved from https://blogs.otago.ac.nz/go Conference Contribution - Published proceedings: Abstract
Tschirley, A. M., Stockwell, P. A., Rodger, E. J., Eltherington, O., Morison, I. M., Christensen, N., Chatterjee, A., & Hibma, M. (2021). The mouse papillomavirus epigenetic signature is characterised by DNA hypermethylation after lesion regression. Viruses, 13, 2045. doi: 10.3390/v13102045 Journal - Research Article
Ludgate, J. L., Weeks, R. J., & Morison, I. M. (2021). Aberrant immunoglobulin kappa locus rearrangement in a patient with CARD11-related B cell lymphocytosis. Journal of Clinical Immunology, 41, 1943-1945. doi: 10.1007/s10875-021-01114-3 Journal - Research Other
Sneyd, M. J., Gray, A. R., & Morison, I. M. (2021). Trends in survival from myeloma, 1990-2015: A competing risks analysis. BMC Cancer, 21, 821. doi: 10.1186/s12885-021-08544-7 Journal - Research Article
Almomani, S. N., Alsaleh, A. A., Weeks, R. J., Chatterjee, A., Day, R. C., Honda, I., … Fukuzawa, R., Slatter, T. L., Hung, N. A., Devenish, C., Morison, I. M., & Macaulay, E. C. (2021). Identification and validation of DNA methylation changes in pre-eclampsia. Placenta, 110, 16-23. doi: 10.1016/j.placenta.2021.05.005 Journal - Research Article
Sneyd, M. J., Gray, A., & Morison, I. M. (2021). Regional distribution of myeloma in New Zealand. New Zealand Medical Journal, 134(1531), 11-22. Retrieved from https://www.nzma.org.nz/journal Journal - Research Article
Mayyas, I. M., Weeks, R. J., Day, R. C., Magrath, H. E., O’Connor, K. M., Kardailsky, O., Hore, T. A., Hampton, M. B., & Morison, I. M. (2021). Hairpin-bisulfite sequencing of cells exposed to decitabine documents the process of DNA demethylation. Epigenetics, 16(11), 1251-1259. doi: 10.1080/15592294.2020.1861169 Journal - Research Article
Weeks, R. J., Ludgate, J. L., Le Mée, G., Khanal, R., Mehta, S., Williams, G., Slatter, T. L., Braithwaite, A. W., & Morison, I. M. (2020). Silencing of Testin expression is a frequent event in spontaneous lymphomas from Trp53-mutant mice. Scientific Reports, 10, 16255. doi: 10.1038/s41598-020-73229-3 Journal - Research Article
Antony, J., Gimenez, G., Taylor, T., Khatoon, U., Day, R., Morison, I. M., & Horsfield, J. A. (2020). BET inhibition prevents aberrant RUNX1 and ERG transcription in STAG2 mutant leukaemia cells. Journal of Molecular Cell Biology, 12(5), 397-399. doi: 10.1093/jmcb/mjz114 Journal - Research Other
Macaulay, E. C., Almomani, S., Lynch-Sutherland, C. F., Chatterjee, A. C., Stockwell, P. A., Alsaleh, A. A., Wilson, J. L., Weeks, R. J., Day, R. C., Fukuzawa, R., Slatter, T. L., Hung, N. A., Devenish, C., Morison, I. M., & Eccles, M. R. (2019, August-September). The placental potential: Harnessing insights from placental epigenetics to predict disease. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chai, K. Y., Boyke Berahmana, A. A., & Morison, I. M. (2019). Haematologists usually over-estimate the percentage of CD138+ plasma cells in marrow biopsies. Pathology, 51(6), 647-648. doi: 10.1016/j.pathol.2019.05.010 Journal - Research Other
Sneyd, M. J., Cox, B., & Morison, I. M. (2019). Trends in myeloma incidence, mortality and survival in New Zealand (1985–2016). Cancer Epidemiology, 60, 55-59. doi: 10.1016/j.canep.2019.03.006 Journal - Research Article
Ledgerwood, E. C., Dunstan-Harrison, C., Ong, L., & Morison, I. M. (2019). CYCS gene variants associated with thrombocytopenia. Platelets, 30(5), 672-674. doi: 10.1080/09537104.2018.1543866 Journal - Research Other
Antony, J., Giminez, G., Khatoon, U., Day, R., Morison, I., & Horsfield, J. (2018). Targeted disruption of the cohesin subunit STAG2 leads to loss of insulation and inappropriate gene activation in response to differentiation signals. Blood, 132(Suppl. 1), (pp. 878). doi: 10.1182/blood-2018-99-117965 Conference Contribution - Published proceedings: Abstract
Mayyas, I., Weeks, R., Hampton, M., Hore, T., & Morison, I. (2018, August). Mechanisms of active DNA demethylation in somatic cells. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Das, A. B., Kakadia, P. M., Morison, I. M., Bohlander, S. K., & Vissers, M. C. M. (2018, August). The potential use of ascorbate as an epigenetic therapeutic in acute myeloid leukaemia. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Das, A., Morison, I., Kennedy, M., & Vissers, M. (2018, April). The potential use of ascorbate as an epigenetic therapeutic in acute myeloid leukaemia by enhancing 2-oxoglutarate dependent dioxygenase activity. Poster session presented at the Keystone Symposium: Therapeutic Targeting of Hypoxia-Sensitive Pathways, Oxford, UK. Conference Contribution - Poster Presentation (not in published proceedings)
Falisse, E., Ducos, B., Stockwell, P. A., Morison, I. M., Chatterjee, A., & Silvestre, F. (2018). DNA methylation and gene expression alterations in zebrafish early-life stages exposed to the antibacterial agent triclosan. Environmental Pollution, 243(Part B), 1867-1877. doi: 10.1016/j.envpol.2018.10.004 Journal - Research Article
Das, A., Morison, I., Bohlander, S., & Vissers, M. (2018). The potential use of ascorbate as an epigenetic therapeutic in acute myeloid leukaemia. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/ Conference Contribution - Published proceedings: Abstract
Halliday, B. J., Fukuzawa, R., Markie, D. M., Grundy, R. G., Ludgate, J. L., Black, M. A., … Weeks, R. J., … Morison, I. M. (2018). Germline mutations and somatic inactivation of TRIM28 in Wilms tumour. PLoS Genetics, 14(6), e1007399. doi: 10.1371/journal.pgen.1007399 Journal - Research Article
Sharp, P. A., Clarkson, R., Hussain, A., Weeks, R. J., & Morison, I. M. (2018). DNA methylation of hepatic iron sensing genes and the regulation of hepcidin expression. PLoS ONE, 13(5), e0197863. doi: 10.1371/journal.pone.0197863 Journal - Research Article
Chai, K. Y., Byrne, A. L., & Morison, I. M. (2018). Roxithromycin monotherapy inducing a partial response in a patient with myeloma: A case report. Journal of Medical Case Reports, 12, 124. doi: 10.1186/s13256-018-1636-9 Journal - Research Other
Mayyas, I., Weeks, R., Hampton, M., & Morison, I. (2017). Mechanisms of active DNA demethylation in somatic cells. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 770. Retrieved from http://gen2017.w.events4you.currinda.com Conference Contribution - Published proceedings: Abstract
Das, A., Morison, I., Kennedy, M., & Vissers, M. (2017, October). The potential use of ascorbate as an epigenetic drug in acute myeloid leukaemia. Poster session presented at the New Zealand Society for Oncology (NZSO) Conference, Auckland, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. (2017, June). Tissue-specific epigenetic markers and disease discovery. Invited presentation at the Southern Health Symposium, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Alsaleh, A., Weeks, R., & Morison, I. (2017). Using DNA methylation to investigate a novel model for childhood acute lymphoblastic leukemia. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 762. Retrieved from http://gen2017.w.events4you.currinda.com Conference Contribution - Published proceedings: Abstract
Almomani, S., Morison, I., Hung, N., Slatter, T., & Macaulay, E. (2017). Predicting altered methylation patterns in early pre-eclampsia. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 778. Retrieved from http://gen2017.w.events4you.currinda.com Conference Contribution - Published proceedings: Abstract
Parakra, R., McDonald, K. O., Ong, L., Todd, P., Mohamad Nor, A., Morison, I. M., Jameson, G. N. L., & Ledgerwood, L. (2017, September). Insights into function from naturally occurring cytochrome c mutations. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Momani, S., Morison, I. M., Hung, N. A., Slatter, T. L., & Macaulay, E. C. (2017, September). Predicting altered methylation patterns in early pre-eclampsia. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Mayyas, I., Weeks, R., Hampton, M., & Morison, I. (2017, September). Mechanisms of active DNA demethylation in somatic cells. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. M., Weeks, R. J., Macaulay, E. C., Alsaleh, A. A., Almomani, S. N., & Day, R. C. (2017, September). Tissue-specific epigenetic markers and disease discovery. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Antony, J., Morison, I. M., & Horsfield, J. A. (2017, September). Dysregulated transcriptional response to differentiation signals in cohesin-mutant myeloid cells. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Fukuzawa, R., Anaka, M. R., Morison, I. M., & Reeve, A. E. (2017). The developmental programme for genesis of the entire kidney is recapitulated in Wilms tumour. PLoS ONE, 12(10), e0186333. doi: 10.1371/journal.pone.0186333 Journal - Research Article
Macaulay, E. C., Momani, S., Hung, N. A., Slatter, T. L., Devenish, C., & Morison, I. M. (2017, September). Profiling the placental epigenome in pre-eclampsia to predict pregnancy outcomes. Invited presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Macaulay, E. C., Chatterjee, A., Cheng, X., Baguley, B. C., Eccles, M. R., & Morison, I. M. (2017). The genes of life and death: A potential role for placental-specific genes in cancer: Active retrotransposons in the placenta encode unique functional genes that may also be used by cancer cells to promote malignancy. BioEssays, 39(11), 1700091. doi: 10.1002/bies.201700091 Journal - Research Article
Ludgate, J. L., Wright, J., Stockwell, P. A., Morison, I. M., Eccles, M. R., & Chatterjee, A. (2017). A streamlined method for analysing genome-wide DNA methylation patterns from low amounts of FFPE DNA. BMC Medical Genomics, 10, 54. doi: 10.1186/s12920-017-0290-1 Journal - Research Article
Sharp, P., Weeks, R., & Morison, I. (2017). DNA methylation regulates the expression of Transferrin receptor 2. American Journal of Hematology, 92(8), (pp. E314). doi: 10.1002/ajh.24812 Conference Contribution - Published proceedings: Abstract
Chatterjee, A., Macaulay, E. C., Ahn, A., Ludgate, J. L., Stockwell, P. A., Weeks, R. J., Parry, M. F., Foster, T. J., … Eccles, M. R., & Morison, I. M. (2017). Comparative assessment of DNA methylation patterns between reduced representation bisulfite sequencing and Sequenom EpiTyper methylation analysis. Epigenomics, 9(6), 823-832. doi: 10.2217/epi-2016-0176 Journal - Research Article
Chatterjee, A., Rodger, E. J., Morison, I. M., Eccles, M. R., & Stockwell, P. A. (2017). Tools and strategies for analysis of genome-wide and gene-specific DNA methylation patterns. In G. J. Seymour, M. P. Cullinan & N. C. K. Heng (Eds.), Oral biology: Molecular techniques and applications: Methods in molecular biology (Vol. 1537). (2nd ed.) (pp. 249-277). New York, NY: Springer. doi: 10.1007/978-1-4939-6685-1_15 Chapter in Book - Research
Chatterjee, A., Rodger, E. J., Stockwell, P. A., Le Mée, G., & Morison, I. M. (2017). Generating multiple base-resolution DNA methylomes using reduced representation bisulfite sequencing. In G. J. Seymour, M. P. Cullinan & N. C. K. Heng (Eds.), Oral biology: Molecular techniques and applications: Methods in molecular biology (Vol. 1537). (2nd ed.) (pp. 279-298). New York, NY: Springer. doi: 10.1007/978-1-4939-6685-1_16 Chapter in Book - Research
Ong, L., Morison, I. M., & Ledgerwood, E. C. (2017). Megakaryocytes from CYCS mutation-associated thrombocytopenia release platelets by both proplatelet-dependent and -independent processes. British Journal of Haematology, 176(2), 268-279. doi: 10.1111/bjh.14421 Journal - Research Article
Macaulay, E. C., Chatterjee, A., Rodger, E. J., Stockwell, P. A., Parry, M. F., Roberts, H. E., Slatter, T. L., Hung, N. A., & Morison, I. M. (2016, March). Placental hypomethylation is more pronounced in genomic loci devoid of retroelements. Poster session presented at the Keystone Symposia on Molecular and Cellular Biology: Chromatin and Epigenetics, Whistler, Canada. Conference Contribution - Poster Presentation (not in published proceedings)
Momani, S., Macaulay, E., Roberts, H., Hung, N., Slatter, T., Devenish, C., & Morison, I. (2016, August-September). Predicting altered methylation patterns in early pre-eclampsia. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Chatterjee, A., Macaulay, E. C., Rodger, E. J., Stockwell, P. A., Parry, M. F., Roberts, H. E., Slatter, T. L., Hung, N. A., Devenish, C. J., & Morison, I. M. (2016). Placental hypomethylation is more pronounced in genomic loci devoid of retroelements. Genes Genomes Genetics, 6(7), 1911-1921. doi: 10.1534/g3.116.030379 Journal - Research Article
Weeks, R. J., Ludgate, J. L., LeMée, G., & Morison, I. M. (2016). TESTIN induces rapid death and suppresses proliferation in childhood B acute lymphoblastic leukaemia cells. PLoS ONE, 11(3), e0151341. doi: 10.1371/journal.pone.0151341 Journal - Research Article
Chatterjee, A., Stockwell, P. A., Rodger, E. J., & Morison, I. M. (2016). Genome-scale DNA methylome and transcriptome profiling of human neutrophils. Scientific Data, 3, 160019. doi: 10.1038/sdata.2016.19 Journal - Research Article
Momani, S., Macaulay, E., Roberts, H., Hung, N., Slatter, T., Devenish, C., & Morison, I. (2015, August-September). Predicting altered methylation patterns in early pre-eclampsia. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Alsaleh, A. A., Weeks, R. J., & Morison, I. M. (2015, August-September). Using epigenetics to identify the fetal cell of origin for childhood B-cell acute lymphoblastic leukaemia. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. M., Macaulay, E. C., & Chatterjee, A. (2015, August-September). Patterns of placental methylation and implications for placental disease and cancer. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chatterjee, A., Stockwell, P. A., Rodger, E. J., Duncan, E. J., Parry, M. F., Weeks, R. J., & Morison, I. M. (2015). Genome-wide DNA methylation map of human neutrophils reveals widespread inter-individual epigenetic variation. Scientific Reports, 5, 17328. doi: 10.1038/srep17328 Journal - Research Article
Macaulay, E. C., Roberts, H. E., Al-Momani, S., Hung, N. A., Slatter, T. L., Devenish, C., & Morison, I. M. (2015). Methylome meets maternity ward: Predicting pre-eclampsia in early pregnancy. Proceedings of the 6th ACM Conference on Bioinformatics, Computational Biology and Health Informatics (BCB). (pp. 484-485). New York: ACM. doi: 10.1145/2808719.2811419 Conference Contribution - Published proceedings: Full paper
Josephs, T. M., Hibbs, M. E., Ong, L., Morison, I. M., & Ledgerwood, E. C. (2015). Interspecies variation in the functional consequences of mutation of cytochrome c. PLoS ONE, 10(6), e0130292. doi: 10.1371/journal.pone.0130292 Journal - Research Article
Ong, L., Morison, I. M., & Ledgerwood, E. C. (2015). Investigating the cause of thrombocytopenia cargeeg. Proceedings of the 27th National Conference on Microscopy. Retrieved from http://microscopy2015.otago.ac.nz/index.html Conference Contribution - Published proceedings: Abstract
Morison, I. (2015) Catalogue of parent of origin effects: Imprinted genes and related effects, University of Otago, Dunedin, New Zealand. Retrieved from http://igc.otago.ac.nz/home.html Other Research Output
Hodgson, T. O., Ruskova, A., Shugg, C. J., McCallum, V. J., & Morison, I. M. (2015). Green neutrophil and monocyte inclusions: Time to acknowledge and report. British Journal of Haematology, 170, 229-235. doi: 10.1111/bjh.13434 Journal - Research Article
Nishina-Uchida, N., Fukuzawa, R., Hasegawa, Y., & Morison, I. M. (2015). Identification of X monosomy cells from a gonad of mixed gonadal dysgenesis with a 46,XY karyotype. Medicine, 94(14), e720. doi: 10.1097/md.0000000000000720 Journal - Research Other
Morison, I. (2014) Catalogue of parent of origin effects: Imprinted genes and related effects, University of Otago, Dunedin, New Zealand. Retrieved from http://igc.otago.ac.nz/home.html Other Research Output
Rodger, E. J., Chatterjee, A., & Morison, I. M. (2014). 5-hydroxymethylcytosine: A potential therapeutic target in cancer. Epigenomics, 6(5), 503-514. doi: 10.2217/epi.14.39 Journal - Research Article
Chatterjee, A., Stockwell, P. A., Horsfield, J. A., Morison, I. M., & Nakagawa, S. (2014). Base-resolution DNA methylation landscape of zebrafish brain and liver [Data in brief]. Genomics Data, 2, 342-344. doi: 10.1016/j.gdata.2014.10.008 Journal - Research Other
Morison, I., & Smith, G. (2014, August). Improved interpretation of chemistry and haematology lab results. Workshop presentation at the South General Practice Conference & Medical Exhibition (GP CME), Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Rodger, E., Chatterjee, A., Stockwell, P., & Morison, I. (2014). DNA methylation markers of myedysplastic syndrome. New Zealand Medical Journal, 127(1398). Retrieved from http://www.nzma.org.nz/journal Conference Contribution - Published proceedings: Abstract
Morison, I. (2014, March). Epigenetics for the practising haematologist. Verbal presentation at the Haematology Society of Australia and New Zealand (HSANZ) New Zealand Annual Branch Meeting, Palmerston North, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Knarston, I., Macaulay, E., Roberts, H., Slatter, T., Hung, N., Devenish, C., & Morison, I. (2014). Validation of DNA methylation biomarkers for pre-eclampsia. New Zealand Medical Journal, 127(1395). Retrieved from http://www.nzma.org.nz/journal Conference Contribution - Published proceedings: Abstract
Macaulay, E. C., Roberts, H. E., Cheng, X., Jeffs, A. R., Baguley, B. C., & Morison, I. M. (2014). Retrotransposon hypomethylation in melanoma and expression of a placenta-specific gene. PLoS ONE, 9(4), e95840. doi: 10.1371/journal.pone.0095840 Journal - Research Article
Stockwell, P. A., Chatterjee, A., Rodger, E. J., & Morison, I. M. (2014). DMAP: Differential methylation analysis package for RRBS and WGBS data. Bioinformatics, 30(13), 1814-1822. doi: 10.1093/bioinformatics/btu126 Journal - Research Article
Josephs, T. M., Morison, I. M., Day, C. L., Wilbanks, S. M., & Ledgerwood, E. C. (2014). Enhancing the peroxidase activity of cytochrome c by mutation of residue 41: Implications for the peroxidase mechanism and cytochrome c release. Biochemical Journal, 458(2), 259-265. doi: 10.1042/BJ20131386 Journal - Research Article
Lander, R. L., Bailey, K. B., Lander, A. G., Alsaleh, A. A., Costa-Ribeiro, H. C., Mattos, A. P., … Houghton, L. A., Morison, I. M., Williams, S. M., & Gibson, R. S. (2014). Disadvantaged pre-schoolers attending day care in Salvador, Northeast Brazil have a low prevalence of anaemia and micronutrient deficiencies. Public Health Nutrition, 19(9), 1984-1992. doi: 10.1017/s1368980013002310 Journal - Research Article
Morison, I. (2013) Catalogue of parent of origin effects: Imprinted genes and related effects, University of Otago, Dunedin, New Zealand. Retrieved from http://igc.otago.ac.nz/home.html Other Research Output
Morison, I. (2013, September). Beyond the human genome: Cutting-edge developments in leukaemia treatment. Verbal presentation at the Inaugural Genetics Week, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2013, August). Impact of next generation whole genome sequencing on haematology. Verbal presentation at the NZ Institute of Medical Laboratory Science (NZIMLS) Annual Scientific Meeting: Bridging Science and Education, Hamilton, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Macaulay, E. C., Roberts, H. E., Hung, N. A., & Morison, I. M. (2013, July). Epigenetic markers for pre-eclampsia. Poster session presented at the EpiCongress, Boston, USA. Conference Contribution - Poster Presentation (not in published proceedings)
Macaulay, E. C., Roberts, H. E., Hung, N. A., & Morison, I. M. (2013). Epigenetic markers for pre-eclampsia. Proceedings of the Gravida Annual Science Symposium: How Can We Create a Better Future For All New Zealanders? Retrieved from http://www.gravida.org.nz/video/gravida-science-symposium-2013/ Conference Contribution - Published proceedings: Abstract
Josephs, T. M., Morison, I. M., Wilbanks, S. M., Bren, K., & Ledgerwood, E. C. (2013, August). Cytochrome c mutations: Biochemistry and physiology. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Roberts, H. E., Macaulay, E. C., Hung, N. A., & Morison, I. M. (2013, August). Epigenetic profiling of pre-eclamptic placentas. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. M., Chatterjee, A., & Stockwell, P. (2013, August). Epigenetic variation in healthy persons: Where is it and what does it mean? Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chatterjee, A., Ozaki, Y., Stockwell, P. A., Horsfield, J. A., Morison, I. M., & Nakagawa, S. (2013). Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing. Epigenetics, 8(9), 979-989. doi: 10.4161/epi.25797 Journal - Research Article
Roberts, H., Macaulay, E., Hung, N., & Morison, I. (2013). Epigenetic profiling of pre-eclamptic placentas. Placenta, 34(9), (pp. A66). doi: 10.1016/j.placenta.2013.06.199 Conference Contribution - Published proceedings: Abstract
Ludgate, J. L., Le Mée, G., Fukuzawa, R., Rodger, E. J., Weeks, R. J., Reeve, A. E., & Morison, I. M. (2013). Global demethylation in loss of imprinting subtype of Wilms tumor. Genes Chromosomes & Cancer, 52(2), 174-184. doi: 10.1002/gcc.22017 Journal - Research Article
Josephs, T. M., Morison, I. M., Wilbanks, S. M., & Ledgerwood, E. C. (2012). Cytochrome c peroxidase activity and mitochondrial release during apoptosis. Proceedings of the Oxygen Theme Meeting. (pp. 16). Dunedin, New Zealand: University of Otago. Retrieved from https://www.otago.ac.nz/research/otago051864.pdf Conference Contribution - Published proceedings: Abstract
Chatterjee, A., Stockwell, P. A., Rodger, E. J., & Morison, I. M. (2012, September). Base-pair resolution DNA methylation map of neutrophils indicates widespread epigenetic variation among normal individuals. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. (2012) Catalogue of parent of origin effects: Imprinted genes and related effects, University of Otago, Dunedin, New Zealand. Retrieved from http://igc.otago.ac.nz/home.html Other Research Output
Magrath-Cohen, H., Morison, I., & Weeks, R. (2012, November). Oxidative stress induced DNA hemi-hypomethilation and the role of maintenance methylation. Verbal presentation at the Gravida Annual Science Symposium: What Makes the Best Start for a Healthy Life? Palmerston North, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Roberts, H. E., Macaulay, E. C., & Morison, I. M. (2012, November). Epigenetic profiling of pre-eclamptic placentas. Verbal presentation at the Gravida Annual Science Symposium: What Makes the Best Start for a Healthy Life? Palmerston North, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chatterjee, A., Stockwell, P. A., Rodger, E. J., & Morison, I. M. (2012, November). Genome-wide DNA methylation map indicates widespread epigenetic variation in normal individuals. Verbal presentation at the Gravida Annual Science Symposium: What Makes the Best Start for a Healthy Life? Palmerston North, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Salā, S., & Morison, I. (2012). Working towards an improved histopathology service in Samoa through internship in the Southern Community Laboratories in Dunedin Public Hospital. Proceedings of the 5th Annual Otago International Health Research Network (OIHRN) Conference. Retrieved from http://dnmeds.otago.ac.nz/departments/psm/research/international_hlth/conference/programme.html Conference Contribution - Published proceedings: Abstract
Chatterjee, A., Rodger, E. J., Stockwell, P. A., Weeks, R. J., & Morison, I. M. (2012). Technical considerations for reduced representation bisulfite sequencing with multiplexed libraries. Journal of Biomedicine & Biotechnology, 2012, 741542. doi: 10.1155/2012/741542 Journal - Research Article
Chatterjee, A., Stockwell, P. A., Rodger, E. J., & Morison, I. M. (2012, August). Base-pair resolution DNA methylation map of neutrophils indicates widespread epigenetic variation among normal individuals. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Roberts, H. E., Macaulay, E. C., Cheng, S., & Morison, I. M. (2012, August). Retrotransposon hypomethylation is linked to expression of a placenta-specific transcript in melanoma. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Weeks, R. J., Le Mee, G., Ludgate, J., & Morison, I. M. (2012, August). TES(ting) a candidate gene for childhood acute lymphoblastic leukaemia. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Miller, J. C., Thomson, C. D., Williams, S. M., van Havre, N., Wilkins, G. T., Morison, I. M., Ludgate, J. L., & Skeaff, C. M. (2012). Influence of the glutathione peroxidase 1 Pro200Leu polymorphism on the response of glutathione peroxidase activity to selenium supplementation: A randomized controlled trial. American Journal of Clinical Nutrition, 96, 923-931. doi: 10.3945/ajcn.112.043125 Journal - Research Article
Chatterjee, A., Stockwell, P. A., Rodger, E. J., & Morison, I. M. (2012). Comparison of alignment software for genome-wide bisulphite sequence data. Nucleic Acids Research, 40(10), e79. doi: 10.1093/nar/gks150 Journal - Research Article
Oliver, V. F., Miles, H. L., Cutfield, W. S., Hofman, P. L., Ludgate, J. L., & Morison, I. M. (2012). Defects in imprinting and genome-wide DNA methylation are not common in the in vitro fertilization population. Fertility & Sterility, 97(1), 147-153.e7. doi: 10.1016/j.fertnstert.2011.10.027 Journal - Research Article
Rodger, E. J., & Morison, I. M. (2012). Myelodysplastic syndrome in New Zealand and Australia. Internal Medicine Journal, 42(11), 1235-1242. doi: 10.1111/j.1445-5994.2011.02619.x Journal - Research Article
Morison, I. (2011, October). The impact of 'next generation' sequencing technology in the diagnostic laboratory. Verbal presentation at the New Zealand Institute of Medical Laboratory Science Otago Southland Education Seminar, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2011, March). DNA methylation and cell lineage specification: Lessons for and from cancer. Verbal presentation at the New Zealand/Singapore Cancer Symposium, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M., & Weeks, R. J. (2011, February). Epigenetics, imprinting. Verbal presentation at the Inaugural International Cancer Symposium, Wellington, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2011, November). The future role of massively parallel Sequencing in the diagnostic laboratory. Verbal presentation at the New Zealand Institute of Medical Laboratory Science (NZIMLS) Seminar: Immunology Special Interest Group (SIG), Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Weeks, R. J., Le Mee, G., Ludgate, J., & Morison, I. M. (2011, March). TES: A candidate gene for childhood acute lymphoblastic leukaemia. Verbal presentation at the New Zealand/Singapore Cancer Symposium, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chatterjee, A., Stockwell, P. A., Rodger, E. J., & Morison, I. M. (2011, September). Genome-scale DNA methylation mapping: Unraveling inter-individual variation. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Roberts, H., & Morison, I. (2011, September). Allele specific methylation and parent of origin effects: Discovering novel imprinted genes. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Rodger, E. J., Chatterjee, A., & Morison, I. M. (2011, September). Mapping the methylome of myelodysplasia. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Le Mée, G., Weeks, R., & Morison, I. (2011, September). Role of the tumor suppressor gene TES in zebrafish development. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Macaulay, E. C., & Morison, I. M. (2011, November). The intersect of placental epigenetics with placental function and dysfunction. Verbal presentation at the National Research Centre for Growth & Development Science Symposium, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Chatterjee, A., & Morison, I. M. (2011). Monozygotic twins: Genes are not the destiny? [Views and challenges]. Bioinformation, 7(7), 369-370. Journal - Research Other
Morison, I. (2011) Catalogue of parent of origin effects: Imprinted genes and related effects, University of Otago, Dunedin, New Zealand. Retrieved from http://igc.otago.ac.nz/home.html Other Research Output
Bordé, E. C., Ouzegdouh, Y., Ledgerwood, E. C., & Morison, I. M. (2011). Congenital thrombocytopenia and cytochrome c mutation: A matter of birth and death. Seminars in Thrombosis & Hemostasis, 37(6), 664-672. doi: 10.1055/s-0031-1291376 Journal - Research Article
Macaulay, E. C., Weeks, R. J., Andrews, S., & Morison, I. M. (2011). Hypomethylation of functional retrotransposon-derived genes in the human placenta. Mammalian Genome, 22, 722-735. doi: 10.1007/s00335-011-9355-1 Journal - Research Article
Le Mée, G., Weeks, R., Horsfield, J., & Morison, I. (2011, February). Using zebrafish models to study the role of TES in childhood leukaemia (ALL). Verbal presentation at the 12th Australia & New Zealand Zebrafish Meeting, Brisbane, Australia. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M., & Weeks, R. J. (2011). Aberrant DNA methylation in childhood ALL? Proceedings of the Inaugural International Cancer Symposium. Retrieved from http://www.wnmeds.ac.nz/cancersymposium/programme.html Conference Contribution - Published proceedings: Abstract
Morison, I. (2011, February). Epigenetics of haematological malignancies. Verbal presentation at the Inaugural International Cancer Symposium, Wellington, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Daly, E. C., & Morison, I. M. (2010, October). Epigenetics in the placenta: A SINE of the times. Verbal presentation at the International Federation of Placenta Associations (IFPA) Conference: Fetus and Placenta: A Perfect Harmony, Santiago, Chile. Conference Contribution - Verbal presentation and other Conference outputs
Daly, E. C., & Morison, I. M. (2010, June). Differential epigenetic modification of retrotransposon-derived genes in the human placenta. Poster session presented at the Epigenetic Mechanisms in Health & Disease Conference, Brussels, Belgium. Conference Contribution - Poster Presentation (not in published proceedings)
Daly, E., & Morison, I. (2010, August). Dichotomous methylation of retrotransposon-derived genes reveals early human cell lineage commitment. Verbal presentation at the National Research Centre for Growth & Development Science Symposium, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Daly, E. C., & Morison, I. M. (2010). Differential epigenetic modification of retrotransposon-derived genes in the human placenta. Proceedings of the Genetics Society of America Conference: Model Organisms to Human Biology. (pp. 72-73). Retrieved from http://www.genetics-gsa.org/pages/conferences.shtml Conference Contribution - Published proceedings: Abstract
Morison, I. M., & Reik, W. (2010). Nutrition, environment and epigenetics. In M. E. Symonds & M. M. Ramsay (Eds.), Maternal-fetal nutrition during pregnancy and lactation. (pp. 180-195). Cambridge University Press. Chapter in Book - Research
Morison, I. M., & Weeks, R. J. (2010, October). Epigenetics of haematopoietic differentiation and neoplasia. Verbal presentation at the Haematology Society of Australia and New Zealand, The Australian & New Zealand Society of Blood Transfusion and the Australasian Society of Thrombosis and Haemostasis (HAA) Annual Scientific Meeting, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2010) Catalogue of parent of origin effects: Imprinted genes and related effects, University of Otago, Dunedin, New Zealand. Retrieved from http://igc.otago.ac.nz/home.html Other Research Output
Miller, J. C., van Havre, N., Wilkins, G., Sutherland, W., de Jong, S., Morison, I. M., Ludgate, J. L., Drake, K. M., Williams, S., Skeaff, C. M., & Thomson, C. D. (2010, May-June). Effect of polymorphisms in the glutathione peroxidase 1 gene on enzyme activity in response to selenium supplementation. Verbal presentation at the 9th International Symposium on Selenium in Biology and Medicine, Kyoto, Japan. Conference Contribution - Verbal presentation and other Conference outputs
Bell, C. G., Finer, S., Lindgren, C. M., Wilson, G. A., Rakyan, V. K., Teschendorff, A. E., … Morison, I. M., … Hitman, G. A. (2010). Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO Type 2 diabetes and obesity susceptibility locus. PLoS ONE, 5(11), e14040. doi: 10.1371/journal.pone.0014040 Journal - Research Article
Josephs, T., Fagerlund, R., Hughes, G., Morison, I., Wilbanks, S., & Ledgerwood, L. (2010, September). Does the first naturally occurring mutation of Cytochrome C challenge the current understanding of apoptosis? Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Chatterjee, A., Rodger, E. J., & Morison, I. M. (2010, September). Genome-scale DNA methylation mapping in normal population. Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Weeks, R. J., Kees, U. R., Song, S., & Morison, I. M. (2010). Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia. Molecular Cancer, 9, 163. doi: 10.1186/1476-4598-9-163 Journal - Research Article
Daly, E. C., & Morison, I. M. (2009, September-October). An epigenetic analysis of first-trimester human placenta. Verbal presentation at the National Research Centre for Growth & Development Science Symposium, Hamilton, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M., Weeks, R. J., Oliver, V. F., & Daly, E. C. (2009, February). Rapidly changing technologies in the epigenetics of development. Verbal presentation at the Centre for Reproduction and Genomics First Annual Research Colloquium, Mosgiel, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Glaser, R. L., & Morison, I. M. (2009). Equality of the sexes? Parent-of-origin effects on transcription and de novo mutations. In S. Krawetz (Ed.), Bioinformatics for systems biology. (pp. 485-513). New York: Springer. doi: 10.1007/978-1-59745-440-7_26 Chapter in Book - Research
Morison, I. (2009, August). New genes in AML/MDS. Verbal presentation at the Haematology Society of Australia and New Zealand (HSANZ ) (NZ) Winter Update Meeting, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Oliver, V., Cutfield, W., Miles, H., Hofman, P., & Morison, I. (2009). Epigenetic defects are uncommon after in vitro fertilisation. New Zealand Medical Journal, 122(1299). Retrieved from http://journal.nzma.org.nz/journal/122-1299/3706/content.pdf Conference Contribution - Published proceedings: Abstract
Morison, I. (2009) Catalogue of parent of origin effects: Imprinted genes and related effects, University of Otago, Dunedin, New Zealand. [Database Maintenance]. Other Research Output
Daly, E. C., & Morison, I. (2009, September). Turning off tumours: The placental potential. Poster session presented at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. (2009, September). Epigenetics: Plastic or programmed? Verbal presentation at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Ledgerwood, E. C., & Morison, I. M. (2009). Targeting the apoptosome for cancer therapy. Clinical Cancer Research, 15(2), 420-424. doi: 10.1158/1078-0432.CCR-08-1172 Journal - Research Article
Fukuzawa, R., Anaka, M. R., Weeks, R. J., Morison, I. M., & Reeve, A. E. (2009). Canonical WNT signalling determines lineage specificity in Wilms tumour. Oncogene, 28(8), 1063-1075. doi: 10.1038/onc.2008.455 Journal - Research Article
Morison, I., Ledgerwood, E. C., Cramer, E. M., Cheong, P. L., Hughes, G., Holyoake, A. J., & Fichelson, S. (2008). Familial thrombocytopenia caused by a pro-apoptotic mutation of cytochrome C. Haematologica, 93(Suppl. 1), (pp. 119). [Abstract] Conference Contribution - Published proceedings: Abstract
Daly, E. C., & Morison, I. M. (2008, November). An epigenetic analysis of first-trimester human placenta. Verbal presentation at the Post-Graduates of Genetics Otago Research Symposium, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2008, August). A New Zealand family with a novel form of thrombocytopenia reveals and unexpected mutation. Verbal presentation at the New Zealand Institute of Medical Laboratory Science and New Zealand Society of Cytology (NZIMLS/NZSC) Conference, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2008, August). The new genetics now includes epigenetics: Whole genome genetic and epigenetic analysis in the future diagnostic laboratory. Verbal presentation at the New Zealand Institute of Medical Laboratory Science and New Zealand Society of Cytology (NZIMLS/NZSC) Conference, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2008, March). Could epigenetics play a role in the developmental origins of health and disease? Verbal presentation at the European Society of Human Reproduction and Embryology (ESHRE) Campus Course, Lisbon, Portugal. Conference Contribution - Verbal presentation and other Conference outputs
Daly, E. C., & Morison, I. M. (2008). Epigenetics in the placenta: A genome-wide methylation analysis of first trimester trophoblasts. Proceedings of the 8th Annual Australasian Microarray and Associated Technologies (AMATA) Conference. Retrieved from http://www.amata.org.au/index.php/resources/2008-conference-abstracts Conference Contribution - Published proceedings: Abstract
Oliver, V., Cutfield, W., Miles, H., Hofman, P., & Morison, I. (2008). Is DNA methylation altered by in vitro fertilisation? Proceedings of the 8th Annual Australasian Microarray and Associated Technologies (AMATA) Conference. Retrieved from http://www.amata.org.au/index.php/resources/2008-conference-abstracts Conference Contribution - Published proceedings: Abstract
Weeks, R. J., & Morison, I. M. (2008, August). Aberrant methylation in childhood leukaemia: Insights into mechanisms of tumorigenesis. Verbal presentation at the New Zealand Society for Oncology (NZSO) Conference, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2008) Catalogue of parent of origin effects: Imprinted genes and related effects, University of Otago, Dunedin, New Zealand. [Database Maintenance]. Other Research Output
Fukuzawa, R., Anaka, M. R., Heathcott, R. W., McNoe, L. A., Morison, I. M., Perlman, E. J., & Reeve, A. E. (2008). Wilms tumour histology is determined by distinct types of precursor lesions and not epigenetic changes. Journal of Pathology, 215(4), 377-387. doi: 10.1002/path.2366 Journal - Research Article
Krueger, C., & Morison, I. M. (2008). Random monoallelic expression: Making a choice. Trends in Genetics, 24(6), 257-259. Journal - Research Article
Morison, I. M., Cramer Bordé, E. M., Cheesman, E. J., Cheong, P. L., Holyoake, A. J., Fichelson, S., Weeks, R. J., Lo, A., Davies, S. M. K., Wilbanks, S. M., Fagerlund, R. D., Ludgate, M. W., da Silva Tatley, F. M., Coker, M. S. A., Bockett, N. A., Hughes, G., Pippig, D. A., Smith, M. P., … Ledgerwood, E. C. (2008). A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia. Nature Genetics, 40(4), 387-389. doi: 10.1038/ng.103 Journal - Research Article
Morison, I. M. (2007, May). Megakaryocyte development and platelet formation. Verbal presentation at the Haematology Society of Australia and New Zealand (HANZ) NZ Branch Meeting, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2007, May). Epigenomic modifications are therapeutic targets in cancer. Verbal presentation at the New Zealand Society for Oncology (NZSO) Conference, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (2007) Catalogue of parent of origin effects: Imprinted genes and related effects, University of Otago, Dunedin, New Zealand. [Database Maintenance]. Other Research Output
Cutfield, W. S., Hofman, P. L., Mitchell, M., & Morison, I. M. (2007). Could epigenetics play a role in the developmental origins of health and disease? Pediatric Research, 61(5), 68R-75R. Journal - Research Article
Elsworthy, J., Venn, B. J., Reeve, A. E., Morison, I. M., & Green, T. J. (2007). No effect of folic acid depletion or repletion on leukocyte DNA methylation overall or by MTHFR 677C→T genotype in healthy individuals. FASEB Journal, 21, 544.12. [Abstract] Conference Contribution - Published proceedings: Abstract
Morison, I. (2006, November). Molecular genetics of disease: Laborator assessment of gene activity and mechanisms of gene regulation. Invited presentation at the New Zealand Society of Gastroenterology Annual Scientific Meeting, Blenheim, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Glaser, R. L., Ramsay, J. P., & Morison, I. M. (2006). The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations. Nucleic Acids Research, 34(Database), D29-D31. Journal - Research Article
Morison, I. M., Weeks, R. J., & Oliver, V. F. (2006, September). Epigenetic regulation of imprinted gene expression. Verbal presentation at the Gene Expression & Chromatin Symposium, Auckland, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Weeks, R. J., & Morison, I. M. (2006). Detailed methylation analysis of CpG islands on human chromosome region 9p21. Genes Chromosomes & Cancer, 45(4), 357-364. Journal - Research Article
Slatter, T. L., Williams, M. J. A., Frikke-Schmidt, R., Tybjærg-Hansen, A., Morison, I. M., & McCormick, S. P. A. (2006). Promoter haplotype of a new ABCA1 mutant influences expression of familial hypoalphalipoproteinemia. Atherosclerosis, 187, 393-400. Journal - Research Article
Drake, K. M., & Morison, I. M. (2005). Analysis of immunoglobulin heavy chain V-D-J and D-J junctional diversity in human fetal B cells. Proceedings of the American Association for Cancer Research (AACR) 96th Annual Meeting. Retrieved from http://www.aacrmeetingabstracts.org/ Conference Contribution - Published proceedings: Abstract
Morison, I. M., Cheong, P. L., Holyoake, A. J., Fichelson, S., Cramer, E. M., & Cheesman, E. J. (2005, August). A new form of familial thrombocytopenia associated with a mutation of cytochrome C. Poster session presented at the 20th International Society of Thrombosis and Haemostasis Congress, Sydney, Australia. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. (2005, October). A census of imprinted genes: Is there still too much missing data for good story telling?. Babraham Seminar Series, Cambridge, UK. [Invited Presentation]. Other Research Output
Wilson, J. L., & Morison, I. M. (2005). No evidence for preferential maternal origin of duplicated chromosome 14 in hyperdiploid ALL. Blood, 105(4), 1837-1838. doi: 10.1182/blood-2004-09-3804 Journal - Research Other
Fukuzawa, R., Heathcott, R. W., Morison, I. M., & Reeve, A. E. (2005). Imprinting, expression, and localisation of DLK1 in Wilms tumours. Journal of Clinical Pathology, 58, 145-150. Journal - Research Article
Fukuzawa, R., Reeve, A. E., & Morison, I. M. (2005). Correct usage of ″Loss of imprinting″ [Correspondence]. American Journal of Medical Genetics Part A, 138A, 412. Journal - Research Other
Morison, I. (Ed.) (2005). A catalogue of imprinted genes and parent-of-origin effects in humans and animals. Dunedin, New Zealand: University of Otago. http://igc.otago.ac.nz/home.html. Dunedin, New Zealand: University of Otago, [Website Update] edition. Retrieved from http://igc.otago.ac.nz/home.html Other Research Output
Morison, I. M., Ramsay, J. P., & Spencer, H. G. (2005). A census of mammalian imprinting. Trends in Genetics, 21(8), 457-465. Journal - Research Article
Slatter, T. L., Williams, M. J., Frikke-Schmidt, R., Tybjærg-Hansen, A., Morison, I., & McCormick, S. P. A. (2004, December). ABCA1 promoter haplotypes influence HDL levels in a novel case of Tangier disease. Poster session presented at the 14th Annual Queenstown Molecular Biology Meeting in conjunction with the New Zealand Society for Biochemical and Molecular Biology Conference, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. M., & Ramsay, J. P. (2004, May). A census of mammalian imprinting. Poster session presented at the Second Weissenburg Symposium, Bayern, Germany. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. M. (2004, August). Reporting haematology results: Redundancy in the full blood count. Verbal presentation at the New Zealand Institute of Medical Laboratory Science Waikato Conference, Wellington, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M. (2004, August). Microarray analysis in lymphoid malignancies. Verbal presentation at the New Zealand Institute of Medical Laboratory Science Waikato Conference, Wellington, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M., Holyoake, A. J., Cramer, E. M., Fichelson, S., & Cheesman, E. J. (2004, March). Family thrombocytopenia: A key to platelet biology. Verbal presentation at the Haematology Society of Australia and New Zealand Conference, Dunedin, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. (Ed.) (2004). A catalogue of imprinted genes and parent-of-origin effects in humans and animals. Dunedin, New Zealand: University of Otago. http://igc.otago.ac.nz/home.html. Retrieved from http://igc.otago.ac.nz/home.html Other Research Output
Fukuzawa, R., Heathcott, R. W., Sano, M., Morison, I. M., Yun, K., & Reeve, A. E. (2004). Myogenesis in Wilms' tumors is associated with mutations of the WT1 gene and activation of Bcl-2 and the Wnt signaling pathway. Pediatric & Developmental Pathology, 7, 125-137. Journal - Research Article
Fukuzawa, R., Breslow, N. E., Morison, I. M., Dwyer, P., Kusafuka, T., Kobayashi, Y., … Reeve, A. E. (2004). Epigenetic differences between Wilms' tumors in white and east-Asian children. Lancet, 363, 446-451. Journal - Research Article
Fukuzawa, R., Heathcott, R. W., Morison, I. M., Reeve, A. E., & Sano, M. (2004). Reply to Dr. Sredni and colleagues. Pediatric & Developmental Pathology, 7, 670. Journal - Research Other
Grant, C. C., Scragg, R., Schaaf, D., Fitzgerald, E., Wilson, N., Ferguson, E., & Morison, I. (2004, October). Low prevalence of iron deficiency in New Zealand children aged five-14 years. Verbal presentation at the Paediatric Society of New Zealand Conference Conference Contribution - Verbal presentation and other Conference outputs
Henaghan, M., Evans, D., Merriman, T., Morison, I., & Tipene-Matua, B. (2003). The regulatory implications of the human genome project for New Zealand: Phase 1. Commissioned by New Zealand Law Foundation. Dunedin, New Zealand: University of Otago. 75p. Commissioned Report for External Body
Morison, I. M., Holyoake, A. J., Cramer, E. M., Fichelson, S., & Cheesman, E. J. (2003, June). Autosomal dominant familial thrombocytopenia associated with a mutation of cytochrome C. Poster session presented at the 8th Meeting of the European Hematology Association, Lyon, France. Conference Contribution - Poster Presentation (not in published proceedings)
Morison, I. M. (2003, October). The genes in childhood ALL provide clues to its origin. Verbal presentation at the HSANZ Annual Scientific Meeting, Christchurch, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Morison, I.(Ed.)(2003) A catalogue of imprinted genes and parent-of-origin effects in humans and animals. Dunedin, New Zealand: University of Otago. http://igc.otago.ac.nz/home.html. Retrieved from http://igc.otago.ac.nz/home.html Other Research Output
Schooten, C. J. M., Ellis, L., & Morison, I. M. (2003). Reassessment of loss of heterozygosity within MLL in childhood acute lymphoblastic leukemia. Blood, 101(10), 4222. Journal - Research Other
Morison, I.(Ed.)(2002) A catalogue of imprinted genes and parent-of-origin effects in humans and animals. Dunedin, New Zealand: University of Otago. http://igc.otago.ac.nz/home.html. [Website Editing]. Other Research Output
Morison, I. M. (2002). The new cancer genetics. Verbal presentation at the Wakefield Hospital's 6th Annual Conference for General Practitioners Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M. (2002). Predictions for the future role of the molecular laboratory in the management of common adult cancer. Verbal presentation at the New Zealand Annual Scientific Meeting of the Royal Australasian College of Surgeons Conference Contribution - Verbal presentation and other Conference outputs
Heathcott, R. W., Morison, I. M., Gubler, M. C., Corbett, R., & Reeve, A. E. (2002). A review of the phenotypic variation due to the Denys-Drash Syndrome-associated germline WT1 mutation R362X. Human Mutation, 19(4), 462. Journal - Research Article
Morison, I. M., Becroft, D. M. O., & Reeve, A. E. (2002). Re: Loss of imprinting of insulin-like growth factor-II (IGF2) gene in distinguishing specific biologic subtypes of Wilms Tumor. Journal of the National Cancer Institute, 94(23), 1809-1810. Journal - Professional & Other Non-Research Articles
Morison, I. M., Ellis, L., Teague, L. R., & Reeve, A. E. (2002). Preferential loss of maternal 9p alleles in childhood acute lymphoblastic leukemia. Blood, 99(1), 375-377. Journal - Research Article
Tycko, B., & Morison, I. M. (2002). Physiological functions of imprinted genes. Journal of Cellular Physiology, 192, 245-258. Journal - Research Article
Reeve, A. E., Becroft, D. M. O., Morison, I. M., & Fukuzawa, R. (2002). IGF2 imprinting in cancer. Lancet, 359, 2050-2051. Journal - Research Article
Morison, I.(Ed.)(2001) A catalogue of imprinted genes and parent-of-origin effects in humans and animals. Dunedin, New Zealand: University of Otago. http://igc.otago.ac.nz/home.html. [Website Editing]. Other Research Output
Morison, I. M. (2001). CLL in a child: 36 years later. Verbal presentation at the Annual Scientific Meeting of the Haematology Society of Australia and New Zealand & New Zealand Society for Oncology Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M., & Ferguson, E. L. (2001). Differences in haemoglobin concentrations reflect physiological differences. British Medical Journal, 323, 806. Journal - Professional & Other Non-Research Articles
Morison, I. M., Paton, C. J., & Cleverley, S. D. (2001). The imprinted gene and parent-of-origin effect database. Nucleic Acids Research, 29(1), 275-276. Journal - Research Article
Morison, I. M. (2001). Thrombophilia testing lacks specificity and clinical utility. Letter in response to Clinical Chemistry 47(9):1597 (2001). Clinical Chemistry. Journal - Professional & Other Non-Research Articles
Ferguson, E. L., Morison, I. M., Faed, J. M., Parnell, W. R., McKenzie, J. E., Wilson, N. C., & Russell, D. G. (2001). Dietary iron intakes and biochemical iron status of 15-49 year old women in New Zealand: Is there a cause for concern? New Zealand Medical Journal, 114, 134-148. Journal - Research Article
Morison, I.(Ed.)(2000) A catalogue of imprinted genes and parent-of-origin effects in humans and animals. Dunedin, New Zealand: University of Otago. http://igc.otago.ac.nz/home.html. [Website Editing]. Other Research Output
Morison, I. M. (2000). Implications of the molecular genetics of childhood acute lymphoblastic leukaemia. Verbal presentation at the Haematology Society of Australia and New Zealand Congress Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M., Ellis, L. M., Mudford, J., & Reeve, A. E. (2000). Clinical and epidemiological implications of molecular genetics studies in childhood acute lymphoblastic leukaemia. Verbal presentation at the New Zealand Society for Oncology Annual Scientific Meeting Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M., Ellis, L. M., Teague, L. R., & Reeve, A. E. (2000). Evidence for germ-line origin of childhood acute leukaemia. Verbal presentation at the Haematology Society of Australia and New Zealand Congress Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M. (2000). Familial thrombocytopenia. Verbal presentation at the Haematology Society of Australia and New Zealand Congress Conference Contribution - Verbal presentation and other Conference outputs
Itoh, N., Becroft, D. M. O., Reeve, A. E., & Morison, I. M. (2000). Proportion of cells with paternal 11p15 uniparental disomy correlates with organ enlargement in Wiedemann-Beckwith Syndrome. American Journal of Medical Genetics, 92, 111-116. Journal - Research Article
Morison, I. M. (2000). Comments on a published paper - Abe "infantile leukemia and soybeans". Leukemia, 14, 524-525. Journal - Professional & Other Non-Research Articles
Morison, I. M., Eccles, M. R., & Reeve, A. E. (2000). Imprinting of insulin-like growth factor 2 is modulated during hematopoiesis. Blood, 96(9), 3023-3028. Journal - Research Article
Morison, I. M. (1999). Molecular genetics in the haematology laboratory [Invited]. Verbal presentation at the Southern Pacific Congress of Medical Laboratory Science Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M. (1999). The role of molecular studies in the diagnosis and management of leukaemia and lymphoma [Invited]. Verbal presentation at the Southern Pacific Congress of Medical Laboratory Science Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M. (1999). A catalogue of imprinted genes and parent-of-origin effects in humans and animals [Website]. University of Otago: Dunedin, New Zealand. Retrieved from http://www.otago.ac.nz/IGC. [Website]. Other Research Output
Ferguson, E. L., Faed, J. M., Morison, I. M., McKenzie, J. D., Parnell, W. R., Wilson, N. C., & Russell, D. G. (1999). Iron status in New Zealand: Is there a public health concern? Pacific Partners in Nutrition, 2nd South-West Pacific Nutrition & Dietetic Conference. Auckland. [Abstract] Conference Contribution - Published proceedings: Abstract
Morison, I. M. (1998). Macrocytosis and polycynthaemia are associated with hereditary haemochromatosis: Implications for concepts of optimal erythropoiesis. Verbal presentation at the Annual Meeting of the New Zealand Society for Haematology Conference Contribution - Verbal presentation and other Conference outputs
Morison, I. M., & Reeve, A. E. (1998, April). IGF2 overexpression and imprinting in overgrowth syndromes. Verbal presentation at the Eli Lilly Global Medical Conference on Pediatric Endocrinology, Indianapolis, USA. Conference Contribution - Verbal presentation and other Conference outputs
Okamoto, K., Morison, I. M., Reeve, A. E., Tommerup, N., Wiedemann, H. R., & Friedrich, U. (1998). Is p57KIP2 mutation a common mechanism for Beckwith-Wiedemann syndrome or somatic overgrowth? Journal of Medical Genetics, 35(1), 86. Journal - Professional & Other Non-Research Articles
Morison, I. M., & Reeve, A. E. (1998). Insulin-like growth factor 2 and overgrowth: Molecular biology and clinical implications. Molecular Medicine Today, 4(3), 110-115. doi: 10.1016/S1357-4310(97)01197-0 Journal - Research Other
Morison, I. M., & Reeve, A. E. (1998). A catalogue of imprinted genes and parent-of-origin effects in humans and animals. Human Molecular Genetics, 7(10), 1599-1609. doi: 10.1093/hmg/7.10.1599 Journal - Research Other
Morison, I. M., Becroft, D. M. O., Taniguchi, T., Okamoto, K., & Reeve, A. E. (1997). Constitutional relaxation of insulin-like growth factor II imprinting is associated with a braod spectrum of overgrowth manifestations. Poster session presented at the American Association for Cancer Research Annual Meeting. Conference Contribution - Poster Presentation (not in published proceedings)
Burt, M. J., Upton, J. D., Morison, I. M., Chapman, B. A., Faed, J. M., & George, P. M. (1997). Molecular analysis of HLA-H gene mutations in New Zealand patients with haemochromatosis. New Zealand Medical Journal, 110(1056), 429-432. Journal - Research Article
Williams, M. J. A., Morison, I. M., Parker, J. H., & Stewart, R. A. H. (1997). Progression of the culprit lesion in unstable coronary artery disease with warfarin and aspirin versus aspirin alone: preliminary study. JACC, 30(2), 364-369. Journal - Research Article
Okamoto, K., Morison, I. M., Taniguchi, T., & Reeve, A. E. (1997). Epigenetic changes at the insulin-like growth factor II/H19 locus in developing kidney is an early event in Wilms tumorigenesis. PNAS, 94(10), 5367-5371. Journal - Research Article
Morison, I. M., Becroft, D. M., Taniguchi, T., Reeve, A. E., & Woods, C. G. (1996). Somatic overgrowth associated with overexpression of insulin—like growth factor II. Nature Medicine, 2, 311-316. doi: 10.1038/nm0396-311 Journal - Research Article
Taniguchi, T., Schofield, A. E., Scarlett, J. L., Morison, I. M., Sullivan, M. J., & Reeve, A. E. (1995). Altered specificity of IGF2 promoter imprinting during fetal development and onset of Wilms tumour. Oncogene, 11, 751-756. Journal - Research Article