Email mark.lokman@otago.ac.nz
Phone 64-3-479-5846
Teaching
- BIOL 112 Animal Biology
- ZOOL 223 Animal Physiology
- ZOOL 313 Animal Function and Environment
- ZOOL 414 Comparative Physiology
- ZOOL 421 Essentials of Molecular Zoology
Research Interests
- Endocrine control of previtellogenic oocyte growth
- Mechanisms controlling fecundity in fish
- Evolution of vertebrate endocrine systems
- Growth and reproduction of aquaculture species in NZ
- Developmental Genetics
Current issues (potential research projects) in the NZ aquaculture industry include:
1. full artificial control of abalone reproduction
2. interaction between growth and reproduction in salmon
3. control of reproduction in eel, hapuka (groper) and giant kokopu
4. development of farming methods for new aquaculture species
Postgraduate Students
- Erin Forbes (PhD) - effects of androgens on eel liver physiology
- Khalid Alqaisi (PhD) - evolution of steroidogenesis in starfish
- Sean Divers (PhD) - induced spawning of eel
- Yair Kohn (PhD) - oogenesis and egg quality in hapuka
- Ali Falahati (PhD) - GDF-9 signaling in the eel ovary
- Alireza (Hamed) Shoae (PhD) - the ovarian IGF-I system in eel
- Sam Van der Horst (MSc) - effects of steroids on eel heaptocytes
- Tasman Gillies (MSc) - spawning induction in abalone
Publications
Baker, N. J., Boubee, J., Lokman, P. M., & Bolland, J. D. (2020). Evaluating the impact of hydropower on downstream migrating anguillid eels: Catchment-wide and fine-scale approaches to identify cost-effective solutions. Science of the Total Environment, 748, 141111. doi: 10.1016/j.scitotenv.2020.141111
Akhavan, S. R., Falahatkar, B., McCormick, S. P. A., & Lokman, P. M. (2020). Changes in lipid biology during ovarian development in farmed beluga sturgeon, Huso huso L. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 319, R376-R386. doi: 10.1152/ajpregu.00364.2019
Rahdari, A., Khoshkholgh, M., Yarmohammadi, M., Ortiz-Zarragoitia, M., Lokman, P. M., Akhavan, S. R., … Falahatkar, B. (2020). The effects of 11-ketotestosterone implants on transcript levels of gonadotropin receptors, foxl2 and dmrt1 genes in the Previtellogenic ovary of cultured beluga (Huso huso). Journal of Fish Biology, 97, 374-382. doi: 10.1111/jfb.14366
Damsteegt, E. L., Thomson-Laing, G., Wylie, M. J., & Lokman, P. M. (2020). Effects of estradiol and 11-ketotestosterone pre-treatment on artificial induction of maturation in silver female shortfinned eels (Anguilla australis). PLoS ONE, 15(2), e0229391. doi: 10.1371/journal.pone.0229391
Nguyen, A. T., Chia, J. H. Z., Kazeto, Y., Wylie, M. J., & Lokman, P. M. (2020). Induction of oocyte development in previtellogenic eel, Anguilla australis. General & Comparative Endocrinology, 291, 113404. doi: 10.1016/j.ygcen.2020.113404
Chapter in Book - Research
Young, G., Kusakabe, M., Nakamura, I., Lokman, P. M., & Goetz, F. W. (2005). Gonadal steroidogenesis in teleost fish. In P. Melamed & N. Sherwood (Eds.), Molecular aspects of fish and marine biology (vol. 4): Hormones and their receptors in fish reproduction. (pp. 155-223). Singapore: World Scientific.
Lokman, P. M., Rohr, D. H., Davie, P. S., & Young, G. (2003). The physiology of silvering in anguillid eels: Androgens and control of metamorphosis from the yellow to silver stage. In K. Aida, K. Tsukamoto & K. Yamauchi (Eds.), Eel biology. (pp. 331-349). Tokyo: Springer.
Journal - Research Article
Baker, N. J., Boubee, J., Lokman, P. M., & Bolland, J. D. (2020). Evaluating the impact of hydropower on downstream migrating anguillid eels: Catchment-wide and fine-scale approaches to identify cost-effective solutions. Science of the Total Environment, 748, 141111. doi: 10.1016/j.scitotenv.2020.141111
Nguyen, A. T., Chia, J. H. Z., Kazeto, Y., Wylie, M. J., & Lokman, P. M. (2020). Induction of oocyte development in previtellogenic eel, Anguilla australis. General & Comparative Endocrinology, 291, 113404. doi: 10.1016/j.ygcen.2020.113404
Damsteegt, E. L., Thomson-Laing, G., Wylie, M. J., & Lokman, P. M. (2020). Effects of estradiol and 11-ketotestosterone pre-treatment on artificial induction of maturation in silver female shortfinned eels (Anguilla australis). PLoS ONE, 15(2), e0229391. doi: 10.1371/journal.pone.0229391
Rahdari, A., Khoshkholgh, M., Yarmohammadi, M., Ortiz-Zarragoitia, M., Lokman, P. M., Akhavan, S. R., … Falahatkar, B. (2020). The effects of 11-ketotestosterone implants on transcript levels of gonadotropin receptors, foxl2 and dmrt1 genes in the Previtellogenic ovary of cultured beluga (Huso huso). Journal of Fish Biology, 97, 374-382. doi: 10.1111/jfb.14366
Akhavan, S. R., Falahatkar, B., McCormick, S. P. A., & Lokman, P. M. (2020). Changes in lipid biology during ovarian development in farmed beluga sturgeon, Huso huso L. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 319, R376-R386. doi: 10.1152/ajpregu.00364.2019
Smart, D. C., Heenan, S., Lokman, P. M., & Lamare, M. D. (2020). Seasonal reproduction of the blue mussel (Mytilus galloprovincialis) from two locations in southern New Zealand. New Zealand Journal of Marine & Freshwater Research. Advance online publication. doi: 10.1080/00288330.2020.1757472
Horiuchi, M., Izumi, H., Lokman, P. M., Ijiri, S., & Adachi, S. (2020). Relationship between abundance and localization of maternal messenger RNA and egg quality in artificially matured Japanese eel Anguilla japonica. Fisheries Science, 86, 43-56. doi: 10.1007/s12562-019-01377-1
Goikoetxea, A., Damsteegt, E. L., Todd, E. V., McNaughton, A., Gemmell, N. J., & Lokman, P. M. (2020). An in vitro ovarian explant culture system to examine sex change in a hermaphroditic fish. PeerJ, 8, e10323. doi: 10.7717/peerj.10323
Palstra, A. P., Jéhannet, P., Swinkels, W., Heinsbroek, L. T. N., Lokman, P. M., Vesala, S., … Saukkonen, S. (2020). First observation of a spontaneously matured female European eel (Anguilla anguilla). Scientific Reports, 10, 2339. doi: 10.1038/s41598-020-59331-6
Falahati, A., Ozaki, Y., Damsteegt, E. L., Zadmajid, V., Freeman, K. J., & Lokman, P. M. (2020). Spatiotemporal expression of activin receptor-like kinase-5 and bone morphogenetic protein receptor type II in the ovary of shortfinned eel, Anguilla australis. Comparative Biochemistry & Physiology Part B. Advance online publication. doi: 10.1016/j.cbpb.2020.110509
Wylie, M. J., Setiawan, A. N., Irvine, G. W., Elizur, A., Zohar, Y., Symonds, J. E., & Lokman, P. M. (2019). Induced spawning of F1 wreckfish (Hāpuku) Polyprion oxygeneios using a synthetic agonist of gonadotropin-releasing hormone. Fishes, 4(3), 41. doi: 10.3390/fishes4030041
Wylie, M. J., Symonds, J. E., Setiawan, A. N., Irvine, G. W., Liu, H., Elizur, A., & Lokman, P. M. (2019). Transcriptomic changes during previtellogenic and vitellogenic stages of ovarian development in wreckfish (hāpuku), Polyprion oxygeneios (Perciformes). Fishes, 4(1), 16. doi: 10.3390/fishes4010016
Thomas, J. T., Todd, E. V., Muncaster, S., Lokman, P. M., Damsteegt, E. L., Liu, H., … Gemmell, N. J. (2019). Conservation and diversity in expression of candidate genes regulating socially-induced female-male sex change in wrasses. PeerJ, 7, e7032. doi: 10.7717/peerj.7032
Akhavan, S. R., Falahatkar, B., Ward, J. M., & Lokman, P. M. (2019). 11-Ketotestosterone induces oocyte growth, but does not affect oocyte cytology in pre-vitellogenic captive beluga, Huso huso L. Comparative Biochemistry & Physiology Part B, 232, 51-59. doi: 10.1016/j.cbpb.2019.02.009
Nguyen, A. T., Chia, J. H. Z., Kazeto, Y., & Lokman, P. M. (2019). Expression of gonadotropin subunit and gonadotropin receptor genes in wild female New Zealand shortfinned eel (Anguilla australis) during yellow and silver stages. General & Comparative Endocrinology, 272, 83-92. doi: 10.1016/j.ygcen.2018.12.001
Ozaki, Y., Damsteegt, E. L., Setiawan, A. N., Miura, T., & Lokman, P. M. (2019). Expressional regulation of gonadotropin receptor genes and androgen receptor genes in the eel testis. General & Comparative Endocrinology, 280, 123-133. doi: 10.1016/j.ygcen.2019.04.020
Thomson-Laing, G., Damsteegt, E. L., Nagata, J., Ijiri, S., Adachi, S., Todo, T., … Lokman, P. M. (2019). Synergistic effects of estradiol and 11-ketotestosterone on vitellogenin physiology in the shortfinned eel (Anguilla australis). Biology of Reproduction, 100(5), 1319-1332. doi: 10.1093/biolre/ioz007
Jéhannet, P., Kruijt, L., Damsteegt, E. L., Swinkels, W., Heinsbroek, L. T. N., Lokman, P. M., & Palstra, A. P. (2019). A mechanistic model for studying the initiation of anguillid vitellogenesis by comparing the European eel (Anguilla anguilla) and the shortfinned eel (A. australis). General & Comparative Endocrinology, 279, 129-138. doi: 10.1016/j.ygcen.2019.02.018
Stuart, R. E., Closs, G. P., Lokman, P. M., & Jellyman, D. (2019). The influence of environmental cues on the activity of silver eels (Anguilla dieffenbachii) in Lake Manapouri, New Zealand. New Zealand Journal of Marine & Freshwater Research, 53(2), 169-181. doi: 10.1080/00288330.2018.1483955
Matsubara, H., Lokman, P. M., Kazeto, Y., Okumura, H., Ijiri, S., Hirai, T., … Yamauchi, K. (2019). Changes in sex steroids and ovarian steroidogenic enzyme mRNA levels in artificially maturing Japanese eel (Anguilla japonica) and naturally maturing New Zealand longfin eel (Anguilla dieffenbachii) during vitellogenesis. Fishes, 4, 52. doi: 10.3390/fishes4040052
Izumi, H., Gen, K., Lokman, P. M., Hagihara, S., Horiuchi, M., Tanaka, T., … Adachi, S. (2019). Maternal transcripts in good and poor quality eggs from Japanese eel, Anguilla japonica: Their identification by large-scale quantitative analysis. Molecular Reproduction & Development, 86, 1846-1864. doi: 10.1002/mrd.23273
Burgerhout, E., Lokman, P. M., van den Thillart, G. E. E. J. M., & Dirks, R. P. (2019). The time-keeping hormone melatonin: A possible key cue for puberty in freshwater eels (Anguilla spp.). Reviews in Fish Biology & Fisheries, 29, 1-21. doi: 10.1007/s11160-018-9540-3
Wylie, M. J., Setiawan, A. N., Irvine, G. W., Symonds, J. E., Elizur, A., Dos Santos, M., & Lokman, P. M. (2018). Ovarian development of captive F1 wreckfish (hāpuku) Polyprion oxygeneios under constant and varying temperature regimes: Implications for broodstock management. General & Comparative Endocrinology, 257, 86-96. doi: 10.1016/j.ygcen.2017.08.022
Wylie, M. J., Setiawan, A. N., Irvine, G. W., Symonds, J. E., Elizur, A., & Lokman, P. M. (2018). Effects of neuropeptides and sex steroids on the pituitary-gonadal axis of pre-pubertal F1 wreckfish (hāpuku) Polyprion oxygeneios in vivo: Evidence of inhibitory effects of androgens. General & Comparative Endocrinology, 257, 113-121. doi: 10.1016/j.ygcen.2017.08.018
Nguyen, A. T., Tsukamoto, K., & Lokman, P. M. (2018). Composition and distribution of freshwater eels Anguilla spp. in Vietnam. Fisheries Science, 84, 987-994. doi: 10.1007/s12562-018-1239-9
Damsteegt, E. L., Davie, A., & Lokman, P. M. (2018). The evolution of apolipoprotein B and its mRNA editing complex: Does the lack of editing contribute to hypertriglyceridemia? Gene, 641, 46-54. doi: 10.1016/j.gene.2017.10.024
Mordenti, O., Emmanuele, P., Casalini, A., Lokman, P. M., Zaccaroni, A., Di Biase, A., & Parmeggiani, A. (2018). Effect of aromatable androgen (17-methyltestosterone) on induced maturation of silver European eels (Anguilla Anguilla): Oocyte performance and synchronization. Aquaculture Research, 49(1), 442-448. doi: 10.1111/are.13475
Thomson-Laing, G., Jasoni, C. L., & Lokman, P. M. (2018). The effects of migratory stage and 11-ketotestosterone on the expression of rod opsin genes in the shortfinned eel (Anguilla australis). General & Comparative Endocrinology, 257, 211-219. doi: 10.1016/j.ygcen.2017.06.025
Di Biase, A., Lokman, P. M., Govoni, N., Casalini, A., Emmanuele, P., Parmeggiani, A., & Mordenti, O. (2017). Co-treatment with androgens during artificial induction of maturation in female eel, Anguilla anguilla: Effects on egg production and early development. Aquaculture, 479, 508-515. doi: 10.1016/j.aquaculture.2017.06.030
Liu, H., Todd, E. V., Lokman, M. P., Lamm, M. S., Godwin, J. R., & Gemmell, N. J. (2017). Sexual plasticity: A fishy tale. Molecular Reproduction & Development, 84(2), 171-194. doi: 10.1002/mrd.22691
Setiawan, A. N., Muncaster, S., Pether, S., King, A., Irvine, G. W., Lokman, P. M., & Symonds, J. E. (2016). The effects of gonadotropin-releasing hormone analog on yellowtail kingfish Seriola lalandi (Valenciennes, 1833) spawning and egg quality. Aquaculture Reports, 4, 1-9. doi: 10.1016/j.aqrep.2016.05.001
Wylie, M. J., Closs, G. P., Damsteegt, E. L., & Lokman, P. M. (2016). Effects of salinity and temperature on artificial cultivation and early ontogeny of giant kokopu, Galaxias argenteus (Gmelin 1789). Aquaculture Research, 47(5), 1472-1480. doi: 10.1111/are.12605
Lokman, P. M., Damsteegt, E. L., Wallace, J., Downes, M., Goodwin, S. L., Facoory, L. J., & Wylie, M. J. (2016). Dose-responses of male silver eels, Anguilla australis, to human chorionic gonadotropin and 11-ketotestosterone in vivo. Aquaculture, 463, 97-105. doi: 10.1016/j.aquaculture.2016.05.009
Damsteegt, E. L., Ozaki, Y., McCormick, S. P. A., & Lokman, P. M. (2016). Triacylglyceride physiology in the shortfinned eel, Anguilla australis: The effects of androgen. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 310, R422-R431. doi: 10.1152/ajpregu.00149.2015
Alqaisi, K. M., Lamare, M. D., Grattan, D. R., Damsteegt, E. L., Schneider, W. J., & Lokman, P. M. (2016). A comparative study of vitellogenesis in Echinodermata: Lessons from the sea star. Comparative Biochemistry & Physiology Part A, 198, 72-86. doi: 10.1016/j.cbpa.2016.04.013
Di Biase, A., Casalini, A., Emmanuele, P., Mandelli, M., Lokman, P. M., & Mordenti, O. (2016). Controlled reproduction in Anguilla anguilla (L.): Comparison between spontaneous spawning and stripping-insemination approaches. Aquaculture Research, 47(10), 3052-3060. doi: 10.1111/are.12755
Damsteegt, E. L., McHugh, N., & Lokman, P. M. (2016). Storage by lyophilization: Resulting RNA quality is tissue dependent. Analytical Biochemistry, 511, 92-96. doi: 10.1016/j.ab.2016.08.005
Kohn, Y. Y., Symonds, J. E., Kleffmann, T., Nakagawa, S., Lagisz, M., & Lokman, P. M. (2015). Proteomic analysis of early-stage embryos: Implications for egg quality in hapuku (Polyprion oxygeneios). Fish Physiology & Biochemistry, 41(6), 1403-1417. doi: 10.1007/s10695-015-0095-0
Akhavan, S. R., Falahatkar, B., Tolouei Gilani, M. H., & Lokman, P. M. (2015). Effects of estradiol-17β implantation on growth rate, ovarian growth, sex steroid levels and vitellogenin proxies in previtellogenic sturgeon Huso huso. Animal Reproduction Science, 157, 1-10. doi: 10.1016/j.anireprosci.2014.12.010
Zadmajid, V., Falahatimarvast, A., Damsteegt, E. L., Setiawan, A. N., Ozaki, Y., Shoae, A., & Lokman, P. M. (2015). Effects of 11-ketotestosterone and temperature on inhibin subunit mRNA levels in the ovary of the shortfinned eel, Anguilla australis. Comparative Biochemistry & Physiology Part B, 187, 14-21. doi: 10.1016/j.cbpb.2015.04.012
Lokman, P. M., Wylie, M. J., Downes, M., Di Biase, A., & Damsteegt, E. L. (2015). Artificial induction of maturation in female silver eels, Anguilla australis: The benefits of androgen pre-treatment. Aquaculture, 437, 1111-1119. doi: 10.1016/j.aquaculture.2014.11.026
Senior, A. M., Lokman, M. P., Closs, G. P., & Nakagawa, S. (2015). Ecological and evolutionary applications for environmental sex reversal of fish. Quarterly Review of Biology, 90(1), 23-44. doi: 10.1086/679762
Damsteegt, E. L., Falahatimarvast, A., McCormick, S. P. A., & Lokman, P. M. (2015). Triacylglyceride physiology in the short-finned eel, Anguilla australis: Changes throughout early oogenesis. American Journal of Physiology: Regulatory, Integrative & Comparative Physiology, 308(11), R935-R944. doi: 10.1152/ajpregu.00436.2014
Damsteegt, E. L., Mizuta, H., Ozaki, Y., Hiramatsu, N., Todo, T., Hara, A., … Lokman, P. M. (2014). Development and partial characterisation of an antiserum against apolipoprotein B of the short-finned eel, Anguilla australis. Journal of Comparative Physiology B, 184(5), 589-599. doi: 10.1007/s00360-014-0821-4
Akbaripasand, A., Ramezani, J., Lokman, P. M., & Closs, G. P. (2014). Can drifting invertebrates meet the energy requirements of drift-feeding fish? A Case Study on Galaxias fasciatus. Freshwater Science, 33(3), 904-914. doi: 10.1086/676957
Johnson, S. L., Villarroel, M., Rosengrave, P., Carne, A., Kleffmann, T., Lokman, P. M., & Gemmell, N. J. (2014). Proteomic analysis of Chinook salmon (Oncorhynchus tshawytscha) ovarian fluid. PLoS ONE, 9(8), e104155. doi: 10.1371/journal.pone.0104155
Lokman, P. M., & Symonds, J. E. (2014). Molecular and biochemical tricks of the research trade: -omics approaches in finfish aquaculture. New Zealand Journal of Marine & Freshwater Research, 48(3), 492-505. doi: 10.1080/00288330.2014.928333
Akbaripasand, A., Ramezani, J., Lokman, P. M., & Closs, G. P. (2014). Does social status within a dominance hierarchy mediate individual growth, residency and relocation? Oecologia, 176(3), 771-779. doi: 10.1007/s00442-014-3038-z