Contact Details
- Phone
- +64 3 479 7379
- dorothy.oorschot@otago.ac.nz
University Links
- Position
- Professor
- Department
- Department of Anatomy
- Qualifications
- BSc(Hons)(W Aust) PhD(Otago)
- Research summary
- Brain research, hypoxia, stem cells, stereology, connectomics
Research
Brain research, including investigation of the effects of low oxygen levels (hypoxia) during the second trimester, or around birth, on brain development. Investigation of treatments to rescue the hypoxic-injured brain, including researching the restorative potential of adult-sourced stem cells. Mapping of the microcircuitry of the brain (i.e. connectomics) during health, and after injury, using electron microscopy. Three-dimensional anatomical methods used (i.e. stereology), primarily to increase knowledge on the basal ganglia of the brain. Stereological advice provided on request.
Publications
Oorschot, D. E., Gowing, E. K., Seo, S., & Kohe, S. E. (2023). Cellular neuroanatomy helps attention deficit hyperactivity disorder (ADHD). Proceedings of the 10th Asia Pacific International Congress of Anatomists (APICA) and the 20th Australian & New Zealand Association of Clinical Anatomists (ANZACA) Conference: Reconnect, Ka Mua, Ka Muri. Retrieved from https://apica2023.com Conference Contribution - Published proceedings: Abstract
Tomlinson, J. C. L., Zwirner, J., Oorschot, D. E., Morawski, M., Ondruschka, B., Zhang, M., & Hammer, N. (2023). Microstructural analysis on the innervation of the anterior, medial, and lateral human hip capsule: Preliminary evidence on its neuromechanical contribution. Osteoarthritis & Cartilage. Advance online publication. doi: 10.1016/j.joca.2023.07.009 Journal - Research Article
Kohe, S. E., Gowing, E. K., Seo, S., & Oorschot, D. E. (2023). A novel rat model of ADHD-like hyperactivity/impulsivity after delayed reward has selective loss of dopaminergic neurons in the right ventral tegmental area. International Journal of Molecular Sciences, 24, 11252. doi: 10.3390/ijms241411252 Journal - Research Article
Seo, S., Parr-Brownlie, L., Bilkey, D., Hughes, S., & Oorschot, D. (2023, June). Opposite changes in midbrain dopamine microcircuitry in the repeated hypoxic rat model of ADHD-like hyperactivity/impulsivity versus the maternal immune activation rat model of schizophrenia: Potential bases for new therapies. Poster session presented at the International Basal Ganglia Society (IBAGS) XIV Meeting, Stockholm, Sweden. Conference Contribution - Poster Presentation (not in published proceedings)
Zhou, Y., Richard, S., Batchelor, N. J., Oorschot, D. E., Anderson, G. M., & Pankhurst, M. W. (2022). Anti-Müllerian hormone-mediated preantral follicle atresia is a key determinant of antral follicle count in mice. Human Reproduction, 37(11), 2635-2645. doi: 10.1093/humrep/deac204 Journal - Research Article
2023
Journal - Research Article
Tomlinson, J. C. L., Zwirner, J., Oorschot, D. E., Morawski, M., Ondruschka, B., Zhang, M., & Hammer, N. (2023). Microstructural analysis on the innervation of the anterior, medial, and lateral human hip capsule: Preliminary evidence on its neuromechanical contribution. Osteoarthritis & Cartilage. Advance online publication. doi: 10.1016/j.joca.2023.07.009
Kohe, S. E., Gowing, E. K., Seo, S., & Oorschot, D. E. (2023). A novel rat model of ADHD-like hyperactivity/impulsivity after delayed reward has selective loss of dopaminergic neurons in the right ventral tegmental area. International Journal of Molecular Sciences, 24, 11252. doi: 10.3390/ijms241411252
Conference Contribution - Published proceedings: Abstract
Oorschot, D. E., Gowing, E. K., Seo, S., & Kohe, S. E. (2023). Cellular neuroanatomy helps attention deficit hyperactivity disorder (ADHD). Proceedings of the 10th Asia Pacific International Congress of Anatomists (APICA) and the 20th Australian & New Zealand Association of Clinical Anatomists (ANZACA) Conference: Reconnect, Ka Mua, Ka Muri. Retrieved from https://apica2023.com
Conference Contribution - Poster Presentation (not in published proceedings)
Seo, S., Parr-Brownlie, L., Bilkey, D., Hughes, S., & Oorschot, D. (2023, June). Opposite changes in midbrain dopamine microcircuitry in the repeated hypoxic rat model of ADHD-like hyperactivity/impulsivity versus the maternal immune activation rat model of schizophrenia: Potential bases for new therapies. Poster session presented at the International Basal Ganglia Society (IBAGS) XIV Meeting, Stockholm, Sweden.
2022
Journal - Research Article
Zhou, Y., Richard, S., Batchelor, N. J., Oorschot, D. E., Anderson, G. M., & Pankhurst, M. W. (2022). Anti-Müllerian hormone-mediated preantral follicle atresia is a key determinant of antral follicle count in mice. Human Reproduction, 37(11), 2635-2645. doi: 10.1093/humrep/deac204
Carrasco, A., Oorschot, D. E., Barzaghi, P., & Wickens, J. R. (2022). Three-dimensional spatial analyses of cholinergic neuronal distributions across the mouse septum, nucleus basalis, globus pallidus, nucleus accumbens, and caudate-putamen. Neuroinformatics, 20, 1121-1136. doi: 10.1007/s12021-022-09588-1
Zhou, Y., Neyt, C., Batchelor, N. J., Kelley, R. L., Jaafar Amsak, K., Anderson, G. M., Oorschot, D. E., Jasoni, C. L., Girling, J. E., & Pankhurst, M. W. (2022). Fetal resorption coincides with dysregulated LH secretion in AMH-overexpressing mice. Journal of Endocrinology, 253(2), 53-62. doi: 10.1530/joe-21-0430
Conference Contribution - Verbal presentation and other Conference outputs
Zhou, Y., Richard, S., Batchelor, N. J., Oorschot, D. E., Anderson, G. M., & Pankhurst, M. W. (2022, August-September). Anti-Müllerian hormone-mediated preantral follicle atresia is a key determinant of antral follicle counts in mice. Verbal presentation at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2021
Journal - Research Article
Seo, S., Sizemore, R. J., Reader, K. L., Smither, R. A., Wicky, H. E., Hughes, S. M., Bilkey, D. K., Parr-Brownlie, L. C., & Oorschot, D. E. (2021). A schizophrenia risk factor induces marked anatomical deficits at GABAergic-dopaminergic synapses in the rat ventral tegmental area: Essential evidence for new targeted therapies. Journal of Comparative Neurology, 529, 3946-3973. doi: 10.1002/cne.25225
Basham, H. K., Aghoghovwia, B. E., Papaioannou, P., Seo, S., & Oorschot, D. E. (2021). Delayed double treatment with adult-sourced adipose-derived mesenchymal stem cells increases striatal medium-spiny neuronal number, decreases striatal microglial number, and has no subventricular proliferative effect, after acute neonatal hypoxia-ischemia in male rats. International Journal of Molecular Sciences, 22, 7862. doi: 10.3390/ijms22157862
Other Research Output
Oorschot, D. (2021, May). Brain circuitry matters. University of Otago, Dunedin, New Zealand. [Inaugural Professorial Lecture].
2020
Journal - Research Other
Oorschot, D. E., Sizemore, R. J., & Amer, A. R. (2020). Treatment of neonatal hypoxic-ischemic encephalopathy with erythropoietin alone, and erythropoietin combined with hypothermia: History, current status, and future research. International Journal of Molecular Sciences, 21(4), 1487. doi: 10.3390/ijms21041487
2019
Journal - Research Article
Aghoghovwia, B. E., Goddard, L., & Oorschot, D. E. (2019). Long-term fine motor capability on the staircase test correlates with the absolute number, but not the density, of DARPP-positive neurons in the caudate-putamen. Anatomical Record, 302(11), 2040-2048. doi: 10.1002/ar.24196
2018
Journal - Research Article
Pankhurst, M. W., Kelley, R. L., Sanders, R. L., Woodcock, S. R., Oorschot, D. E., & Batchelor, N. J. (2018). Anti-Müllerian hormone overexpression restricts preantral ovarian follicle survival. Journal of Endocrinology, 237(2), 153-163. doi: 10.1530/joe-18-0005
Amer, A. R., & Oorschot, D. E. (2018). Xenon combined with hypothermia in perinatal hypoxic-ischemic encephalopathy: A noble gas, a noble mission. Pediatric Neurology, 84, 5-10. doi: 10.1016/j.pediatrneurol.2018.02.009
Conference Contribution - Published proceedings: Abstract
Seo, S., Sizemore, R. J., Bilkey, D. K., Hughes, S. M., Parr-Brownlie, L. C., & Oorschot, D. E. (2018). Changes in midbrain dopamine circuitry in the maternal immune activation rat model of schizophrenia. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 30). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr
Oorschot, D. E., Seo, S., Bilkey, D. K., Hughes, S. M., Parr-Brownlie, L. C., & Sizemore, R. J. (2018). Synaptic triad arrangement within an aversive pathway in the normal uninjured brain. In K. Hillman (Ed.), Proceedings of the 36th International Australasian Winter Conference on Brain Research. (pp. 29). AWCBR. Retrieved from https://www.otago.ac.nz/awcbr
Conference Contribution - Verbal presentation and other Conference outputs
Pankhurst, M. W., Kelley, R. L., Sanders, R. L., Woodcock, S. R., Oorschot, D. E., & Batchelor, N. J. (2018, November). Why does anti-Müllerian hormone slow the depletion of eggs in the ovary? Verbal presentation at the Women’s Wellbeing Symposium, Dunedin, New Zealand.
2017
Chapter in Book - Research
Oorschot, D. E. (2017). Cell types in the different nuclei of the basal ganglia. In H. Steiner & K. Y. Tseng (Eds.), Handbook of basal ganglia structure and function. (2nd ed.) (pp. 99-117). London, UK: Academic Press. doi: 10.1016/B978-0-12-802206-1.00005-2
Conference Contribution - Published proceedings: Abstract
Oorschot, D. E., Narayanan, S., & Goddard, L. (2017). Post-treatment with melatonin prevents cerebral myelin and memory deficits in male rats exposed to repeated hypoxia during the equivalent of extreme prematurity. Proceedings of the Society for Neuroscience 47th Annual Meeting. 395.04/DD4. SfN. Retrieved from https://www.sfn.org/
Okpe, O., Goddard, L., & Oorschot, D. E. (2017). Treatment of brain injury due to extreme prematurity: Effect of melatonin on ADHD-like hyperactivity and midbrain dopaminergic neurons. Proceedings of the Society for Neuroscience 47th Annual Meeting. 303.23/X15. SfN. Retrieved from https://www.sfn.org/
Aghoghovwia, B. E., & Oorschot, D. E. (2017). Delayed post-treatment with adult-sourced adipose-derived MSCs is neurorestorative of striatal DARPP-32 neurons after neonatal rat HI. Proceedings of the Society for Neuroscience 47th Annual Meeting. 138.05/Z24. SfN. Retrieved from https://www.sfn.org/
Seo, S., Kohe, S. E., Gowing, E., Zheng, Y., Kokay, I., Grattan, D. R., Liu, P., & Oorschot, D. E. (2017). Effect of extreme prematurity on brain monoamine metabolism. Proceedings of the Society for Neuroscience 47th Annual Meeting. 035.06/C44. SfN. Retrieved from https://www.sfn.org/
Conference Contribution - Verbal presentation and other Conference outputs
Oorschot, D. E. (2017, March ). Synaptic connectome of midbrain dopaminergic neurons, striatal spiny projection neurons and striatal cholinergic interneurons in the rat. Verbal presentation at the 12th International Basal Ganglia Society Meeting (IBAGS XII), Mérida, Mexico.
2016
Journal - Research Article
Aghoghovwia, B. E., & Oorschot, D. E. (2016). Absolute number of parvicellular and magnocellular neurons in the red nucleus of the rat midbrain: A stereological study. Journal of Anatomy, 229(3), 406-415. doi: 10.1111/joa.12495
Sizemore, R. J., Zhang, R., Lin, N., Goddard, L., Wastney, T., Parr-Brownlie, L. C., Reynolds, J. N. J., & Oorschot, D. E. (2016). Marked differences in the number and type of synapses innervating the somata and primary dendrites of midbrain dopaminergic neurons, striatal cholinergic interneurons and striatal spiny projection neurons in the rat. Journal of Comparative Neurology, 524(5), 1062-1080. doi: 10.1002/cne.23891
Conference Contribution - Published proceedings: Abstract
Aghoghovwia, B. E., Goddard, L., & Oorschot, D. E. (2016). Effect of delayed post-treatment with adult-sourced adipose-derived mesenchymal stem cells on motor function and striatal medium-spiny projection neurons after neonatal rat hypoxia-ischemia. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 58). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Okpe, O., Goddard, L., & Oorschot, D. E. (2016). Treatment of brain injury due to extreme prematurity: Effect of melatonin on ADHD-like hyperactivity. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 57). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Oorschot, D. E., & Aghoghovwia, B. E. (2016). Absolute number of parvicellular and magnocellular neurons in the red nucleus of the rat midbrain: A stereological study. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 44). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Seo, S., Goddard, L., Parr-Brownlie, L. C., Sizemore, R. J., & Oorschot, D. E. (2016). Marked differences in the number and type of synapses innervating the primary dendrites of nigral versus ventral tegmental dopaminergic neurons, and nigral dopaminergic versus striatal spiny projection neurons, in the rat. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 28). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
2015
Journal - Research Article
Oswald, M. J., Schulz, J. M., Kelsch, W., Oorschot, D. E., & Reynolds, J. N. J. (2015). Potentiation of NMDA receptor-mediated transmission in striatal cholinergic interneurons. Frontiers in Cellular Neuroscience, 9, 116. doi: 10.3389/fncel.2015.00116
Cameron, S. H., Alwakeel, A. J., Goddard, L., Hobbs, C. E., Gowing, E. K., Barnett, E. R., Kohe, S. E., Sizemore, R. J., & Oorschot, D. E. (2015). Delayed post-treatment with bone marrow-derived mesenchymal stem cells is neurorestorative of striatal medium-spiny projection neurons and improves motor function after neonatal rat hypoxia-ischemia. Molecular & Cellular Neuroscience, 68, 56-72. doi: 10.1016/j.mcn.2015.03.019
Conference Contribution - Published proceedings: Abstract
Oorschot, D. E., Alwakeel, A. J., Goddard, L., Hobbs, C. E., Gowing, E. K., Barnett, E. R., Kohe, S. E., Sizemore, R. J., & Cameron, S. H. (2015). Delayed post-treatment with bone marrow-derived mesenchymal stem cells is neurorestorative of striatal medium-spiny projection neurons and improves motor function after neonatal rat hypoxia-ischemia. In B. Leitch (Ed.), Proceedings of the 33rd International Australasian Winter Conference on Brain Research. (pp. 31). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Sizemore, R. J., Parr-Brownlie, L. C., Hughes, S. M., & Oorschot, D. E. (2015). Complex GABAergic innervation onto ventral tegmental dopamine neurons. In B. Leitch (Ed.), Proceedings of the 33rd International Australasian Winter Conference on Brain Research. (pp. 30). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Oorschot, D., Zhang, R., Lin, N., Wastney, T., Parr-Brownlie, L. C., Reynolds, J. N. J., & Sizemore, R. J. (2015). A stereological transmission electron microscopy study: Marked differences in the number and type of synapses innervating the somata and primary dendrites of three neuronal subtypes in the rat brain. Proceedings of the 27th National Conference on Microscopy. Retrieved from http://microscopy2015.otago.ac.nz/index.html
Conference Contribution - Verbal presentation and other Conference outputs
Cameron, S. H., Alwakeel, A. J., Goddard, L., Hobbs, C. E., Gowing, E. K., Barnett, E. R., … Sizemore, R. J., & Oorschot, D. E. (2015, July). Delayed post-treatment with bone marrow-derived mesenchymal stem cells is neurorestorative of striatal medium-spiny projection neurons in the brain and improves motor function after neonatal rat hypoxia-ischemia. Verbal presentation at the Perinatal Society of New Zealand (PSNZ) 35th Annual Scientific Meeting, Dunedin, New Zealand.
2014
Journal - Research Article
Barry, M. D., Boddington, L. J., Igelström, K. M., Gray, J. P., Shemmell, J., Tseng, K. Y., Oorschot, D. E., & Reynolds, J. N. J. (2014). Utility of intracerebral theta burst electrical stimulation to attenuate interhemispheric inhibition and to promote motor recovery after cortical injury in an animal model. Experimental Neurology, 261, 258-266. doi: 10.1016/j.expneurol.2014.05.023
Kim, E. H., Thu, D. C. V., Tippett, L. J., Oorschot, D. E., Hogg, V. M., Roxburgh, R., … Faull, R. L. M. (2014). Cortical interneuron loss and symptom heterogeneity in Huntington disease. Annals of Neurology, 75(5), 717-727. doi: 10.1002/ana.24162
Nana, A. L., Kim, E. H., Thu, D. C. V., Oorschot, D. E., Tippett, L. J., Hogg, V. M., … Faull, R. L. M. (2014). Widespread heterogenous neuronal loss across the cerebral cortex in Huntington's disease. Journal of Huntington's Disease, 3(1), 45-64. doi: 10.3233/JHD-140092
Conference Contribution - Published proceedings: Abstract
Oorschot, D. E., Voss, L., Covey, M. V., Goddard, L., Huang, W., Birchall, P. R., Bilkey, D. K., & Kohe, S. E. (2014). Spectrum of short- and long-term brain pathology and long-term behavioural deficits in male repeated hypoxic rats closely resembling human extreme prematurity. Proceedings of the Australasian Neuroscience Society 34th Annual Meeting. Retrieved from http://www.ans.org.au/
Oorschot, D. E., Alwakeel, A. J., Goddard, L., Hobbs, C. E., Gowing, E. K., Barnett, E. R., Kohe, S. E., Sizemore, R. J., & Cameron, S. H. (2014). Delayed post-treatment with bone marrow-derived mesenchymal stem cells is neurorestorative of striatal medium-spiny projection neurons and improves motor function after neonatal rat hypoxia-ischemia. Proceedings of the Society for Neuroscience 44th Annual Meeting. SfN. Retrieved from http://www.sfn.org/annual-meeting/neuroscience-2014/abstracts
Parr-Brownlie, L. C., Sizemore, R. J., Hughes, S. M., & Oorschot, D. E. (2014). Virus infects electron microscopy: Combining techniques for enhanced imaging of brain circuitry. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 32nd International Australasian Winter Conference on Brain Research. 32, (pp. 83). AWCBR. Retrieved from https://web.psy.otago.ac.nz/awcbr/proceedings.html
2013
Journal - Research Article
Oorschot, D. E., Voss, L., Covey, M. V., Goddard, L., Huang, W., Birchall, P., Bilkey, D. K., & Kohe, S. E. (2013). Spectrum of short- and long-term brain pathology and long-term behavioral deficits in male repeated hypoxic rats closely resembling human extreme prematurity. Journal of Neuroscience, 33(29), 11863-11877. doi: 10.1523/jneurosci.0342-12.2013
Oorschot, D. E., Lin, N., Cooper, B. H., Reynolds, J. N. J., Sun, H., & Wickens, J. R. (2013). Synaptic connectivity between rat striatal spiny projection neurons in vivo: Unexpected multiple somatic innervation in the context of overall sparse proximal connectivity. Basal Ganglia, 3, 93-108. doi: 10.1016/j.baga.2013.04.001
Conference Contribution - Published proceedings: Abstract
Oorschot, D. E., & Goddard, L. (2013). Myelin deficits, with no change in the absolute number of mature oligodendrocytes, in male repeated hypoxic rats closely resembles human extreme prematurity. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 31st International Australasian Winter Conference on Brain Research. 31, (pp. 36). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2013copy.html
Faull, R. L. M., Kim, E. H., Thu, D. C. V., Hogg, V., Synek, B., Oorschot, D. E., … Waldvogel, H. J. (2013). Region-specific cortical degeneration is a key component in understanding the neural basis of clinical heterogeneity in Huntington’s disease. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 31st International Australasian Winter Conference on Brain Research. 31, (pp. 33). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2013copy.html
Reynolds, J. N. J., Barry, M. D., Connelly, W. M., Oorschot, D. E., & Abraham, W. C. (2013). Cellular mechanisms underlying modulation of interhemispheric inhibition by theta-burst stimulation. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 31st International Australasian Winter Conference on Brain Research. 31, (pp. 26). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2013copy.html
Conference Contribution - Verbal presentation and other Conference outputs
Sizemore, R. J., Parr-Brownlie, L., Lin, N., Zhang, R., & Oorschot, D. E. (2013, March). Number and type of synapses on the somata and primary dendrites of dopaminergic neurons in the rat ventral tegmental area. Verbal presentation at the 11th Triennial Meeting of the International Basal Ganglia Society (IBAGS-XI), Eilat, Israel.
2012
Journal - Research Article
Oorschot, D. E. (2012). The percentage of interneurons in the dorsal striatum of the rat, cat, monkey and human: A critique of the evidence. Basal Ganglia, 3(1), 19-24. doi: 10.1016/j.baga.2012.11.001
Conference Contribution - Published proceedings: Abstract
Oorschot, D., Voss, L., Covey, M., Huang, W., Birchall, P., Bilkey, D., & Kohe, S. (2012). Spectrum of short- and long-term brain pathology and long-term behavioural deficits in male repeated hypoxic rats closely resembling human extreme prematurity. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 30th International Australasian Winter Conference on Brain Research. 30, (pp. 73). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2012.html
Cameron, S., Goddard, L., Sizemore, R., & Oorschot, D. (2012). Delayed post-treatment with mesenchymal stem cells affects progenitor cell proliferation in the subventricular zone after neonatal rat hypoxic/ischemic striatal injury. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 30th International Australasian Winter Conference on Brain Research. 30, (pp. 65). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2012.html
Kim, E. H., Thu, D. C. V., Hogg, V., Synek, B., Oorschot, D. E., Tippett, L. J., … Faull, R. L. M. (2012). Pyramidal and interneuron cell loss in the motor and cingulate cortex in HD human brain correlates with dominant symptom profile. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 30th International Australasian Winter Conference on Brain Research. 30, (pp. 61). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2012.html
Sizemore, R., Parr-Brownlie, L., & Oorschot, D. (2012). Number and type of synapses on the somata and primary dendrites of dopaminergic neurons in the rat ventral tegmental area. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 30th International Australasian Winter Conference on Brain Research. 30, (pp. 41). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2012.html
Cameron, S., Goddard, L., Sizemore, R., & Oorschot, D. (2012). Delayed post-treatment with bone marrow-derived mesenchymal stem cells affects the proliferation of progenitor cells in the subventricular zone after neonatal rat hypoxic-ischemic brain injury. New Zealand Medical Journal, 125(1355). Retrieved from http://www.nzma.org.nz/journal
2011
Journal - Research Article
Oorschot, D. E. (2011). Indirect measures of neuroprotection are parameters to avoid: Examples from research on neonatal rat hypoxia-ischemia. Image Analysis & Stereology, 30(1), 1-9. doi: 10.5566/ias.v30.p1-9
Conference Contribution - Published proceedings: Abstract
Barry, M. D., Oorschot, D. E., & Reynolds, J. N. J. (2011). Effects of intermittent theta burst stimulation on interhemispheric inhibition in pyramidal neurons of the motor cortex in vivo. Proceedings of the Australasian Neuroscience Society (ANS) Sensorimotor Satellite Meeting. Retrieved from http://www.sensorimotorcontrolmeeting.org
Faull, R., Tippett, L., Thu, D., Nana, A., Kim, E., Oorschot, D., … Curtis, M. (2011). Huntington's disease: New perspectives correlating the variable symptomatology with striatal and cortical pathology and stem cell proliferation in the human brain. Clinical Genetics, 80(Suppl. 1), (pp. 9-10). [Abstract]
Nana, A. L., Tippett, L. J., Hogg, V., Oorschot, D. E., Dragunow, M., Waldvogel, H. J., & Faull, R. L. M. (2011). Cell loss in the cerebral cortex in Huntington's disease. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 161). Retrieved from http://www.ans.org.au/uploads/documents/2011%20Docs/conference%20abstracts/ANS%202011%20Poster%20Abstracts.pdf
Kim, E. H., Thu, D. C. V., Nana, A. L., Oorschot, D. E., Hogg, V. M., Tippett, L. J., … Faull, R. L. M. (2011). Variable cortical interneuronal loss in Huntington's disease human brain correlates with symptom profiles. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 124). Retrieved from http://www.ans.org.au/uploads/documents/2011%20Docs/conference%20abstracts/ANS%202011%20Poster%20Abstracts.pdf
Alwakeel, A., Hobbs, C. E., Gowing, E. K., Barnett, L. R., & Oorschot, D. E. (2011). Effect of delayed mesenchymal stem cell treatment for rat neonatal hypoxia/ischemia. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 116). Retrieved from http://www.ans.org.au/uploads/documents/2011%20Docs/conference%20abstracts/ANS%202011%20Poster%20Abstracts.pdf
Oorschot, D. E., Sizemore, R. J., Lin, N., Wastney, T., Reynolds, J. N. J., & Zhang, R. (2011). Rat striatal cholinergic interneurons have markedly fewer synapses on their soma and primary dendrites compared to striatal spiny projection neurons. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 48). Retrieved from http://www.ans.org.au/uploads/documents/2011%20Docs/conference%20abstracts/ANS%202011%20Oral%20Abstracts.pdf
Oorschot, D. E., Hobbs, C. E., Khouri, B., Barnett, E., Alwakeel, A., & Lim, J.-Y. (2011). Combined antioxidant (S-PBN)-hypothermia treatment, administered immediately post-injury, is not neuroprotective for striatal medium-spiny neurons after neonatal rat hypoxia-ischemia: A dose-response and stereological study. Proceedings of the Society for Neuroscience 41st Annual Meeting. SfN. Retrieved from http://www.sfn.org/am2011/index.aspx?pagename=abstracts_main
Sizemore, R. J., Oorschot, D. E., Lin, N., Wastney, T., Reynolds, J. N. J., & Zhang, R. (2011). Rat striatal spiny projection neurons have markedly more synapses on their somata and primary dendrites compared to striatal cholinergic interneurons. In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 5.49. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html
Conference Contribution - Verbal presentation and other Conference outputs
Oorschot, D. E. (2011, October). Indirect measures of neuroprotection are parameters to avoid: Examples from research on neonatal rat hypoxia-ischemia. Verbal presentation at the 13th International Congress for Stereology, Beijing, China.
Kohe, S. E., Gowing, E. K., & Oorschot, D. E. (2011, October). The effect of aging on the absolute number of dopaminergic neurons in the substantia nigra, retrorubral field, and the ventral tegmental area of the rat midbrain. Verbal presentation at the 13th International Congress for Stereology, Beijing, China.
2010
Chapter in Book - Research
Oorschot, D. E. (2010). Cell types in the different nuclei of the basal ganglia. In H. Steiner & K. Y. Tseng (Eds.), Handbook of basal ganglia structure and function. (pp. 63-74). London: Academic Press. doi: 10.1016/B978-0-12-374767-9.00003-2
Journal - Research Article
Sizemore, R. J., Reynolds, J. N. J., & Oorschot, D. E. (2010). Number and type of synapses on the distal dendrite of a rat striatal cholinergic interneuron: A quantitative, ultrastructural study. Journal of Anatomy, 217, 223-235. doi: 10.1111/j.1469-7580.2010.01264.x
Thu, D. C. V., Oorschot, D. E., Tippett, L. J., Nana, A. L., Hogg, V. M., Synek, B. J., … Faull, R. L. M. (2010). Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease. Brain, 133(4), 1094-1110. doi: 10.1093/brain/awq047
Conference Contribution - Published proceedings: Abstract
Oorschot, D. E., Lin, N., Cooper, B. H., Reynolds, J. N. J., Sun, H., & Wickens, J. R. (2010). Local connectivity between rat striatal spiny projection neurons: A three-dimensional ultrastructural study of somal innervation. Proceedings of the 10th Triennial Meeting of the International Basal Ganglia Society (IBAGS X). (pp. 114). Retrieved from http://www.ibags.info/
Oswald, M. J., Schulz, J. M., Oorschot, D. E., & Reynolds, J. N. J. (2010). Augmentation of the afterhyperpolarization in striatal cholinergic interneurons by repetitive stimulation and dopamine-dependent potentiation of cortical synapses: Implications for spike rate modulation by conditioned stimuli. Proceedings of the 10th Triennial Meeting of the International Basal Ganglia Society (IBAGS X). (pp. 89). Retrieved from http://ibags.info/
Sizemore, R. J., Reynolds, J. N. J., & Oorschot, D. E. (2010). Number and type of synapses on the distal dendrites of rat striatal cholinergic interneurons: A quantitative, ultrastructural study. Proceedings of the 10th Triennial Meeting of the International Basal Ganglia Society (IBAGS X). (pp. 95-96). Retrieved from http://www.ibags.info/
Barry, M. D., Oorschot, D. E., & Reynolds, J. N. J. (2010). Effects of intermittent theta burst stimulation on interhemispheric inhibition recorded in pyramidal neurons of the motor cortex in vivo. In B. Leitch (Ed.), Proceedings of the 28th International Australasian Winter Conference on Brain Research. 28, (pp. 25). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2010.htm
Kim, E., Thu, D. C. V., Nana, A. L., Oorschot, D. E., Synek, B. J., Hogg, V. M., … Faull, R. L. M. (2010). Variable pattern of cortical interneuron loss in the human brain in Huntington's disease correlates with symptom profiles. Proceedings of the Society for Neuroscience 40th Annual Meeting. SfN. Retrieved from http://www.abstractsonline.com/Plan/SSResults.aspx
2009
Journal - Research Article
Oswald, M. J., Oorschot, D. E., Schulz, J. M., Lipski, J., & Reynolds, J. N. J. (2009). IH current generates the afterhyperpolarisation following activation of subthreshold cortical synaptic inputs to striatal cholinergic interneurons. Journal of Physiology, 587(24), 5879-5897. doi: 10.1113/jphysiol.2009.177600
Conference Contribution - Published proceedings: Abstract
Oswald, M. J., Oorschot, D. E., Lipski, J., & Reynolds, J. N. J. (2009). The hyperpolarisation activated current (IH) significantly contributes to the afterhyperpolarisation in striatal cholinergic interneurons. Proceedings of the Australian Neuroscience Society (ANS) Annual Scientific Meeting. (pp. 75). Retrieved from http://www.ans.org.au/uploads/documents/2009%20Docs/ANS%202009%20Poster%20Abstracts.pdf
Oswald, M. J., Oorschot, D. E., & Reynolds, J. N. J. (2009). Augmentation of post-synaptic potentials following dopamine-dependent potentiation of cortical synapses is associated with afterhyperpolarisations in striatal cholinergic interneurons. In R. Napper (Ed.), Proceedings of the 27th International Australasian Winter Conference on Brain Research. 27, (pp. 61). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2009.htm
Kohe, S., Gowing, E., & Oorschot, D. (2009). Decreased absolute number of dopamine neurons in rats exposed to repeated hypoxia during development. New Zealand Medical Journal, 122(1299). Retrieved from http://journal.nzma.org.nz/journal/122-1299/3706/content.pdf
Barry, M. D., Oorschot, D. E., & Reynolds, J. N. J. (2009). Synaptic plasticity effects of intermittent theta burst stimulation on interhemispheric inhibition recorded in pyramidal neurons of the motor cortex. Proceedings of the Society for Neuroscience 39th Annual Meeting. SfN. Retrieved from http://www.abstractsonline.com/plan/AdvancedSearch.aspx
2008
Journal - Research Article
Hobbs, C. E., Murphy, M. P., Smith, R. A. J., & Oorschot, D. E. (2008). Neonatal rat hypoxia-ischemia: Effect of the anti-oxidant mitoquinol, and S-PBN. Pediatrics International, 50(4), 481-488. doi: 10.1111/j.1442-200X.2008.02705.x
Hobbs, C. E., & Oorschot, D. E. (2008). Neonatal rat hypoxia-ischemia: Long-term rescue of striatal neurons and motor skills by combined antioxidant-hypothermia treatment. Brain Pathology, 18(3), 443-454. doi: 10.1111/j.1750-3639.2008.00146.x
Conference Contribution - Published proceedings: Abstract
Kohe, S. E., Covey, M. V., Birchall, P., Bilkey, D. K., & Oorschot, D. E. (2008). Myelin and memory deficits in rats exposed to repeated hypoxia during development: A novel model of extreme prematurity. Proceedings of the Society for Neuroscience 38th Annual Meeting. SfN. Retrieved from http://www.abstractsonline.com/plan/AdvancedSearch.aspx
Oorschot, D. E., Savanthrapadian, S., & Hobbs, C. E. (2008). Neonatal rat hypoxia-ischemia: Rescue of hippocampal CA1 neurons by combined antioxidant-hypothermia treatment. Proceedings of the Society for Neuroscience 38th Annual Meeting. SfN. Retrieved from http://www.abstractsonline.com/plan/AdvancedSearch.aspx
Nana, A. L., Thu, D. C. V., Oorschot, D. E., Tippett, L. J., Hogg, V. M., Waldvogel, H. J., & Faull, R. L. M. (2008). Cell loss in the cerebral cortex in Huntington's disease. In J. G. Anson (Ed.), Proceedings of the 26th International Australasian Winter Conference on Brain Research. 26, (pp. 44). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2008Abstracts.pdf
Oswald, M. J., Lipski, J., Oorschot, D. E., & Reynolds, J. N. J. (2008). The hyperpolarisation-activated current (Ih) significantly contributes to the afterhyperpolarisation in striatal cholinergic interneurons. In J. G. Anson (Ed.), Proceedings of the 26th International Australasian Winter Conference on Brain Research. 26, (pp. 20). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2008Abstracts.pdf
Sizemore, R. J., Reynolds, J. N. J., & Oorschot, D. E. (2008). Synaptic inputs onto cholinergic interneurons in the striatum of the rat: A three-dimensional, ultrastructural mapping study. Proceedings of the Society for Neuroscience 38th Annual Meeting. SfN. Retrieved from http://www.abstractsonline.com/plan/AdvancedSearch.aspx
Oswald, M. J., Lipski, J., Oorschot, D. E., & Reynolds, J. N. J. (2008). The hyperpolarization-activated current (Ih) is a major contributor to the synaptically-induced afterhyperpolarization in striatal cholinergic interneurons. Proceedings of the Society for Neuroscience 38th Annual Meeting. SfN. Retrieved from http://www.abstractsonline.com/plan/AdvancedSearch.aspx
Barry, M. D., Oorschot, D. E., & Reynolds, J. N. J. (2008). Synaptic plasticity in the crossed-cortical pathways induced by intermittent or continuous theta-burst stimulation: An in vivo intracellular investigation. Proceedings of the Society for Neuroscience 38th Annual Meeting. SfN. Retrieved from http://www.abstractsonline.com/plan/AdvancedSearch.aspx
Conference Contribution - Verbal presentation and other Conference outputs
Oorschot, D. (2008, June). Neonatal rat hypoxia-ischemia: Long-term rescue of striatal neurons and motor skills by combined antioxidant-hypothermia treatment. Verbal presentation at the Brain Health and Repair Research Centre 2nd Annual Conference, Dunedin, New Zealand.
2007
Journal - Research Article
Covey, M. V., & Oorschot, D. E. (2007). Effect of hypothermic post-treatment on hypoxic-ischemic striatal injury, and normal striatal development, in neonatal rats: A stereological study. Pediatric Research, 62(6), 646-651.
Oorschot, D. E., Voss, L., Covey, M. V., Bilkey, D. K., & Saunders, S. E. (2007). ADHD-like hyperactivity, with no attention deficit, in adult rats after repeated hypoxia during the equivalent of extreme prematurity. Journal of Neuroscience Methods, 166, 315-322.
Conference Contribution - Poster Presentation (not in published proceedings)
Faull, R., Thu, D., Oorschot, D., Tippett, L., Hogg, V., & Waldvogel, H. (2007, September). Cell loss in the cerebral cortex in Huntington's disease correlates with symptom profiles. Poster session presented at the World Congress on Huntington's Disease, Dresden, Germany.
Oorschot, D. E., Lin, N., Wastney, T., & Zhang, R. (2007, September). Total number and type of synapses on the soma and primary dendrites of spiny projection neurons and cholinergic interneurons in the rat striatum: A three-dimensional, ultrastructural study. Poster session presented at the 9th Triennial Meeting of the International Basal Ganglia Society, Egmond aan Zee, the Netherlands.
Barry, M. D., Oorschot, D. E., & Reynolds, J. N. J. (2007, July). Effect of intermittent theta-burst stimulation on crossed-cortical pathways. Poster session presented at the 7th International Brain Research Organization World Congress of Neuroscience, Melbourne, Australia.
Oswald, M. J., Lipski, J., Oorschot, D. E., & Reynolds, J. N. J. (2007, September). Calcium and sodium ion dependence of the slow afterhyperpolarisation in striatal cholinergic interneurons in response to direct and synaptic stimulation in vitro. Poster session presented at the 9th Triennial Meeting of the International Basal Ganglia Society, Egmond aan Zee, the Netherlands.
Sizemore, R. J., Reynolds, J. N. J., & Oorschot, D. E. (2007, July). Presumptive cortical inputs to cholinergic interneurons in the striatum of the rat. Poster session presented at the 7th International Brain Research Organization World Congress of Neuroscience, Melbourne, Australia.
2006
Journal - Research Article
Covey, M. V., Murphy, M. P., Hobbs, C. E., Smith, R. A. J., & Oorschot, D. E. (2006). Effect of the mitochondrial antioxidant, Mito Vitamin E, on hypoxic-ischemic striatal injury in neonatal rats: A dose-response and stereological study. Experimental Neurology, 199, 513-519.
Zhang, R., & Oorschot, D. E. (2006). Total number of neurons in the habenular nuclei of the rat epithalamus: A stereological study. Journal of Anatomy, 208, 577-585.
Conference Contribution - Published proceedings: Abstract
Saunders, S., Covey, M., Bilkey, D., & Oorschot, D. (2006). Hyperactivity in adult rats after exposure to repeated hypoxia during development: A novel rat model of extreme prematurity that is relevant to attention deficit hyperactivity disorder. New Zealand Medical Journal, 119(1245). Retrieved from http://journal.nzma.org.nz/journal/119-1245/2331/content.pdf
Faull, R. L. M., Waldvogel, H. J., Tippett, L., Thu, D., Curtis, M., & Oorschot, D. E. (2006). Correlation of the genetics, symptomatology, pathology and stem cell proliferation in Huntington's disease. Proceedings of the Australian Neuroscience Society 26th Annual Meeting. 17, (pp. 13). ANS. [Abstract]
Barry, M. D., Oorschot, D. E., & Reynolds, J. N. J. (2006). Mapping the crossed-corticostriatal pathway using antidromic activation. In J. G. Anson (Ed.), Proceedings of the 24th International Australasian Winter Conference on Brain Research. 24, (pp. 51). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2006Abstracts.pdf
Sizemore, R. J., Reynolds, J. N. J., & Oorschot, D. E. (2006). Cortical inputs to cholinergic interneurons in the striatum of the rat: Optimisation of methods. In J. G. Anson (Ed.), Proceedings of the 24th International Australasian Winter Conference on Brain Research. 24, (pp. 35). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2006Abstracts.pdf
Barry, M., Oorschot, D., & Reynolds, J. (2006). Mapping the crossed-corticostriatal pathway using antidromic activation. New Zealand Medical Journal, 119(1245). Retrieved from http://journal.nzma.org.nz/journal/119-1245/2331/content.pdf
Saunders, S. E., Covey, M., Bilkey, D., & Oorschot, D. (2006). Hyperactivity and memory deficits after repeated hypoxia during development: A novel rat model of extreme prematurity. In J. G. Anson (Ed.), Proceedings of the 24th International Australasian Winter Conference on Brain Research. 24, (pp. 25). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2006Abstracts.pdf
Oswald, M. J., Oorschot, D. E., & Reynolds, J. N. J. (2006). Cortical stimulation evokes postsynaptic potentials and slow afterhyperpolarisations in striatal cholinergic interneurons in vitro. In J. G. Anson (Ed.), Proceedings of the 24th International Australasian Winter Conference on Brain Research. 24, (pp. 53). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/2006Abstracts.pdf
2005
Conference Contribution - Published proceedings: Abstract
Thu, D. C. V., Oorschot, D., Tippett, L., Hogg, V., Waldvogel, H. J., & Faull, R. L. M. (2005). Correlation between the pattern of cell loss in the primary motor cortex and cingulate cortex with the pattern of symptomatology in Huntington's disease. Proceedings of the Society for Neuroscience 35th Annual Meeting. (1010.12). Washington DC: SfN. [Abstract]
Oorschot, D. E., Voss, L., Covey, M. V., Bilkey, D. K., Huang, W., Birchall, P., & Saunders, S. E. (2005). Extreme prematurity, repeated hypoxia and attention deficit hyperactivity disorder. Proceedings of the First Dunedin Workshop on the Neurobiology of ADHD. (pp. 16-17). Dunedin, New Zealand: University of Otago. [Abstract]
Thu, D. C. V., Oorschot, D. E., Tippett, L., Hogg, V., Waldvogel, H. J., & Faull, R. L. M. (2005). The variable pattern of cell loss in the cerebral cortex correlates with the variable pattern of symptomatology in Huntington's disease. Journal of Neurology, Neurosurgery & Psychiatry, 76(Suppl. 4), (pp. A16). [Abstract]
2004
Conference Contribution - Published proceedings: Abstract
Hobbs, C., & Oorschot, D. (2004). Long-term rescue of striatal neurons and motor skills by combined antioxidant-hypothermia treatment after neonatal hypoxic-ischemic brain injury in the rat. New Zealand Medical Journal, 117(1202). Retrieved from http://journal.nzma.org.nz/journal/117-1202/1086/content.pdf
Hobbs, C. E., & Oorschot, D. E. (2004). Long-term functional and histological outcomes of antioxidant-hypothermia treatment after neonatal hypoxic-ischemic brain injury in the rat. Proceedings of the International Basal Ganglia Society 8th Triennial Meeting. (pp. 123). [Abstract]
Oorschot, D. E., Lin, N., Reynolds, J. N. J., & Wickens, J. R. (2004). Local connectivity between spiny projection neurons in the rat striatum: A three-dimensional, ultrastructural study. Proceedings of the 8th Triennial Meeting of the International Basal Ganglia Society. (P26), (pp. 46). [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Hobbs, C., & Oorschot, D. (2004, June). Possible help for cerebral palsy. Poster session presented at the MacDiarmid Young Scientists of the Year Awards, Auckland, New Zealand.
Thu, D. C. V., Oorschot, D., Waldvogel, H. J., & Faull, R. L. M. (2004, September). Neuronal loss in the primary motor cortex, primary sensory cortex and cingulate gyrus of the human brain in Huntington's disease. Poster session presented at the International Basal Ganglia Society 8th Triennial Meeting, Crieff, Scotland.
2003
Chapter in Book - Research
Oorschot, D. E., Tompkins, M. M., & Galvin, K. A. (2003). Effect of delayed treatment with basic fibroblast growth factor on the survival of striatal spiny projection neurons after perinatal hypoxia-ischemia. In K. Satoh, S. Suzuki & M. Matsunaga (Eds.), Advances in brain research. Cerebrovascular disorders and neurodegeneration. (pp. 71-79). Amsterdam: Elsevier.
Journal - Research Article
Partadiredja, G., Miller, R., & Oorschot, D. E. (2003). The number, size, and type of axons in rat subcortical white matter on left and right sides: A stereological, ultrastructural study. Journal of Neurocytology, 32, 1165-1179.
Galvin, K. A., & Oorschot, D. E. (2003). Continuous low-dose treatment with brain-derived neurotrophic factor or neurotrophin-3 protects striatal medium spiny neurons from mild neonatal hypoxia/ischemia: A stereological study. Neuroscience, 118, 1023-1032.
Conference Contribution - Published proceedings: Abstract
Hobbs, C. E., & Oorschot, D. E. (2003). Combined antioxidant-hypothermia treatment after hypoxic-ischemic brain injury in the immature rat. Proceedings of 33rd Annual Meeting of the Society for Neuroscience. Washington, DC: Society for Neuroscience. Retrieved from http://sfn.scholarone.com/itin2003
Covey, M. V., & Oorschot, D. E. (2003). Effect of mild or moderate hypothermia following hypoxic-ischemic injury to the immature rat striatum: A stereological study. Proceedings of 33rd Annual Meeting of the Society for Neuroscience. Washington, DC: Society for Neuroscience. Retrieved from http://sfn.scholarone.com/itin2003
Oorschot, D. E., Lin, N., Reynolds, J. N. J., & Wickens, J. R. (2003). Local connectivity among spiny projection neurons in the rat striatum: A three-dimensional, ultrastructural study. Proceedings of 33rd Annual Meeting of the Society for Neuroscience. Washington, DC: Society for Neuroscience. Retrieved from http://sfn.scholarone.com/itin2003
Conference Contribution - Poster Presentation (not in published proceedings)
Hobbs, C. E., & Oorschot, D. E. (2003, June). Preventing the loss of nerve cells in cerebral palsy. Poster session presented at the FiRST Scholarship and Career Development Conference 2003, Christchurch, New Zealand.
2002
Chapter in Book - Research
Oorschot, D. E., Tunstall, M., & Wickens, J. (2002). Local connectivity between striatal spiny projection neurons: A re-evaluation. In L. Nicholson & R. L. N. Faull (Eds.), The Basal Ganglia VII. (pp. 421-434). USA: Plenum Publishers.
Journal - Research Article
Tunstall, M., Oorschot, D. E., Kean, A., & Wickens, J. (2002). Inhibitory interactions between spiny projection neurons in the rat striatum. Journal of Neurophysiology, 10, 1263-1269.
Conference Contribution - Published proceedings: Abstract
Stone, C. E., Murphy, M. P., Smith, R. A. J., & Oorschot, D. E. (2002). Are the free radical scavengers mitoquinol or N-tert-butyl-(2-suffophenyl)-nitrone (S-PBN) protective for striatal medium-spiny neurons following an acute hypoxic-ischemic insult to the immature rat brain? Pediatric Research. 51(4), (pp. 444). Baltimore, USA: Lippincott, Williams and Wilkins (eds). [Abstract]
Oorschot, D. E., Tompkins, M., & Galvin, K. A. (2002). Perinatal hypoxia-ischemia, striatal injury and growth factor treatments. Proceedings of the 6th Meeting of the Hirosaki International Forum of Medical Science. (pp. 26). Hirosaki, Japan: Hirosaki University School of Medicine. [Abstract]
Covey, M. V., & Oorschot, D. E. (2002). Does pre-treatment with magnesium sulphate (MgSO4), a glutamate receptor antagonist, protect striatal medium-spiny neurons against acute hypoxic-ischemic brain injury in the immature rat? Pediatric Research. 51(4), (pp. 444). Baltimore, USA: Lippincott, Williams and Wilkins. [Abstract]
2001
Conference Contribution - Published proceedings: Abstract
Zhang, R., & Oorschot, D. E. (2001). Analysis of somal and dendritic synapses on cholinergic interneurons in the rat striatum: A three-dimensional ultrastructural study. In L. F. B. Nicholson & R. L. M. Faull (Eds.), Proceedings of the VIIth International Basal Ganglia Society Conference. (pp. 105). New Zealand: University of Auckland. [Abstract]
Covey, M. V., Murphy, M. P., Stone, C. E., Coulter, C. V., Smith, R. A. J., & Oorschot, D. E. (2001). Does vitamin E-triphenylphosphonium (Vit E-TPP) protect striatal medium spiny neurons against acute hypoxic-ischemic brain injury in the immature rat? In L. F. B. Nicholson & R. L. M. Faull (Eds.), Proceedings of the VIIth International Basal Ganglia Society Conference. (pp. 112). New Zealand: University of Auckland. [Abstract]
Oorschot, D. E., Lin, N., Cooper, B. H., Sun, H., Reynolds, J. N. J., & Wickens, J. R. (2001). Direct ultrastructural evidence of synaptic contact between rat striatal medium-spiny neurons: A three dimensional electron microscopic study. In L. F. B. Nicholson & R. L. M. Faull (Eds.), Proceedings of the VIIth International Basal Ganglia Society Conference. (pp. 101). New Zealand: University of Auckland. [Abstract]
Tunstall, M. J., Kean, A., Wickens, J. R., & Oorschot, D. E. (2001). Inhibitory interactions between spiny projection neurons of the striatum: A physiological and anatomical study. In L. F. B. Nicholson & R. L. M. Faull (Eds.), Proceedings of the VIIth International Basal Ganglia Society Conference. (pp. 38). New Zealand: University of Auckland. [Abstract]
Wickens, J. R., Hardwick, C. R., Reynolds, J. N. J., & Oorschot, D. E. (2001). Colocalization of receptors for dopamine D1- and D2-like antagonists on spiny neurons in the rat striatum. In L. F. B. Nicholson & R. L. M. Faull (Eds.), Proceedings of the VIIth International Basal Ganglia Society Conference. (pp. 58). New Zealand: University of Auckland. [Abstract]
2000
Chapter in Book - Research
Wickens, J., & Oorschot, D. E. (2000). Neural dynamics and surround inhibition in the neostriatum: A possible connection. In R. Miller & J. R. Wickens (Eds.), Conceptual Advances in Brain Research, Brain Dynamics and the Striatal Complex. (pp. 141-150). Amsterdam: Harwood Academic.
Oorschot, D. E. (2000). The domain hypothesis: A central organizing principle for understanding neostriatal circuitry? In R. Miller & J. R. Wickens (Eds.), Conceptual Advances in Brain Research, Brain Dyamics and the Striatal Complex. (pp. 151-163). Amsterdam: Harwood Academic.
Journal - Research Article
Oorschot, D. E., Black, M. J., Rangi, F., & Scarr, E. (2000). Is Fos protein expressed by dying striatal neurons after immature hypoxic-ischemic brain injury? Experimental Neurology, 161, 227-233.
Journal - Research Other
Oorschot, D. E. (2000). Cerebral palsy and experimental hypoxia-induced perinatal brain injury: Is magnesium protective? Magnesium Research, 13(4), 265-273. [Review].
1999
Conference Contribution - Published proceedings: Abstract
Oorschot, D. E., Van Reisen, M. T., Lin, N., Cooper, B. H., & Wickens, J. (1999). Three-dimensional reconstruction of synaptic inputs and synapse/astrocyte topography in the rat neostriatum. Proceedings of the 17th International Australasian Winter Conference on Brain Research. 34. Queenstown, New Zealand. [Abstract]
Franks, S. J., Oorschot, D. E., & Grattan, D. R. (1999). Changes in the number of axo-spinous synapses in the ventromedial hypothalmic nucleus during the estrous cycle of the rat. Proceedings of the Physiological Society of New Zealand. 18. Wellington. [Abstract]
Oorschot, D. E., & Galvin, K. A. (1999). Treatment with neurotrophin-3 or brain-derived neurotrophic factor protects striatal medium spiny neurons against immature hypoxic/ischemic brain injury in the rat: A stereological study. Proceedings of the 29th Annual Meeting of the Society for Neuroscience. 909. Miami Beach, Florida. [Abstract]
Oorschot, D. E., Zhang, R., & Wickens, J. (1999). Absolute number and three-dimensional spatial distribution of rat neostriatal large interneurons: A first and second order stereological study. Proceedings of the Xth International Congress for Stereology. (pp. 87). Melbourne. [Abstract]
1998
Journal - Research Article
Galvin, K. A., & Oorschot, D. E. (1998). Postinjury magnesium sulfate treatment is not markedly neuroprotective for striatal medium spiny neurons after perinatal hypoxia/ischemia in the rat. Pediatric Research, 44, 740-745. doi: 10.1203/00006450-199811000-00017
Jones, K. R., & Oorschot, D. E. (1998). Do aluminium and/or glutamate induce Alz-50 reactivity? A light microscopic immunohistochemical study. Journal of Neurocytology, 27, 45-57.
Jones, K. R., Black, M. J., & Oorschot, D. E. (1998). Do aluminium and/or glutamate induce Alzheimer PHF-like formation? An electron microscopic study. Journal of Neurocytology, 27, 59-68.
Oorschot, D. E., & McLennan, I. S. (1998). The trophic requirements of mature motoneurons. Brain Research, 789, 315-321.
Conference Contribution - Published proceedings: Abstract
Oorschot, D. E., Mexted, M. J., Rangi, F., & Scarr, E. (1998). Fos protein expression after immature hypoxic-ischemic brain injury. International Journal of Neuroscience. 94. [Abstract]
Oorschot, D. E. (1998). The total number of rat thalamic parafascicular neurons, and the total number and spatial array of their target neurons, the large neostriatal interneurons: a stereological study. Proceedings of the VIth Triennial International Basal Ganglia Society Conference. (pp. 66). Massachussetts, USA. [Abstract]
Stuart, D. A., & Oorschot, D. E. (1998). The effect of interleukin-3 on microglia and macrophages within the lesioned adult rat spinal cord. Proceedings of the Asia Pacific Symposium on Neural Regeneration. (pp. 45). Hong Kong. [Abstract]
1997
Conference Contribution - Published proceedings: Abstract
Oorschot, D. E. (1997). Total number of large interneurons within the rat neostriatum: A stereological study using the optical disector and Cavalieri methods. International Journal of Neuroscience. 89. [Abstract]
Oorschot, D. E., & Galvin, K. A. (1997). Neuron-to-astrocyte ratios within rat basal ganglia. International Journal of Neuroscience. 89. [Abstract]
1996
Journal - Research Article
Oorschot, D. E. (1996). Total number of neurons in the neostriatal, pallidal, subthalamic, and substantia nigral nuclei of the rat basal ganglia: a stereological study using the Cavalieri and optical disector methods. Journal of Comparative Neurology, 366, 580-599.
1995
Journal - Research Article
Stuart, D., & Oorschot, D. E. (1995). Embedding, sectioning, immunocytochemical and stereological methods that optimise research on the lesioned adult rat spinal cord. Journal of Neuroscience Methods, 61, 5-14.