2021
Journal - Research Article
Stanton, J.-A. L., O'Brien, R., Hall, R. J., Chernyavtseva, A., Ha, H. J., Jelley, L., Mace, P. D., … Treece, J. M., … Ussher, J. E., … Hore, T. A., Moser, T. V., Harfoot, R., Lawley, B., Quiñones‑Mateu, M. E., … Blaikie, R. (2021). Uncoupling molecular testing for SARS-CoV-2 from international supply chains. Frontiers in Public Health, 9, 808751. doi: 10.3389/fpubh.2021.808751
2020
Journal - Research Article
Bates, A., Laven, R., O'Brien, R., Liggett, S., & Griffin, F. (2020). Estimation of the sensitivity and specificity of four serum ELISA and one fecal PCR for diagnosis of paratuberculosis in adult dairy cattle in New Zealand using Bayesian latent class analysis. Preventive Veterinary Medicine, 185, 105199. doi: 10.1016/j.prevetmed.2020.105199
2019
Journal - Research Article
Bates, A., O'Brien, R., Liggett, S., & Griffin, F. (2019). Control of Mycobacterium avium subsp. paratuberculosis infection on a New Zealand pastoral dairy farm. BMC Veterinary Research, 15, 266. doi: 10.1186/s12917-019-2014-6
2018
Journal - Research Article
Bates, A., O'Brien, R., Liggett, S., & Griffin, F. (2018). The effect of sub-clinical infection with Mycobacterium avium subsp. paratuberculosis on milk production in a New Zealand dairy herd. BMC Veterinary Research, 14, 93. doi: 10.1186/s12917-018-1421-4
2017
Journal - Research Other
Thomas, R. R., Brooks, H. J. L., & O'Brien, R. (2017). Prevalence of Shiga toxin-producing and enteropathogenic Escherichia coli marker genes in diarrhoeic stools in a New Zealand catchment area [Short report]. Journal of Clinical Pathology, 70(1), 81-84. doi: 10.1136/jclinpath-2016-203882
2016
Journal - Research Article
Mackintosh, C. G., Griffin, J. F. T., Scott, I. C., O'Brien, R., Stanton, J. L., Maclean, P., & Brauning, R. (2016). SOLiD SAGE sequencing shows differential gene expression in jejunal lymph node samples of resistant and susceptible red deer (Cervus elaphus) challenged with Mycobacterium avium subsp. paratuberculosis. Veterinary Immunology & Immunopathology, 169, 102-110. doi: 10.1016/j.vetimm.2015.10.009
2015
Conference Contribution - Published proceedings: Full paper
O'Brien, R., Liggett, S., Brennan, L., Mackintosh, C., & Griffin, F. (2015). A model for the heritabilty of susceptibility or resilience to Johne's disease. Proceedings of the Society of Sheep and Beef Veterinarians of the New Zealand Veterinary Association and Cervetec Conference [NZVA Publication No. 309]. (pp. 143-153). Wellington, New Zealand: NZVA. [Full Paper]
Conference Contribution - Poster Presentation (not in published proceedings)
Lange, J., Ussher, J., O'Brien, R., & Hannaway, R. (2015, August-September). Role of mucosal associated invariant T (MAIT) cells in cervine Johne's disease. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Ussher, J., Hannaway, R., Lange, J., O'Brien, R., Griffin, F., Murdoch, D., & Klenerman, P. (2015, August-September). MAIT cells: Key cellular effectors in antibacterial immunity? Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Griffin, J. F. T., Liggett, S., Brennan, L., Mackintosh, G., & O'Brien, R. (2015, August-September). Biomarkers for resilience and susceptibility to mycobacterial infection: Model studies in deer. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2014
Conference Contribution - Published proceedings: Abstract
Mackintosh, C. G., de Lisle, G., O'Brien, R., Clark, R. G., & Griffin, F. (2014). Diverse experiences arising from a MAP infection model in red deer. Proceedings of the 12th International Colloquium on Paratuberculosis (ICP). (pp. 201-203). Retrieved from http://www.paratuberculosis.info/
Brennan, L., O'Brien, R., & Griffin, F. (2014). Genetic markers for resilience and susceptibility to Johne's disease in red deer. Proceedings of the 12th International Colloquium on Paratuberculosis (ICP). (pp. 180). Retrieved from http://www.paratuberculosis.info/
Griffin, F., Liggett, S., Brennan, L., Mackintosh, C. G., Marfell, B., & O'Brien, R. (2014). Selection for heritable resistance is an option to control Johne's disease in ruminants. Proceedings of the 12th International Colloquium on Paratuberculosis (ICP). (pp. 166). Retrieved from http://www.paratuberculosis.info/
O'Brien, R., Liggett, S., & Griffin, F. (2014). Serological assay followed up by quantitative PCR: A synergistic combo for ante-mortem diagnosis of Johne's disease in farmed New Zealand deer. Proceedings of the 12th International Colloquium on Paratuberculosis (ICP). (pp. 93). Retrieved from http://www.paratuberculosis.info/
2013
Journal - Research Article
Marfell, B. J., O'Brien, R., & Griffin, J. F. T. (2013). Global gene expression profiling of monocyte-derived macrophages from red deer (Cervus elaphus) genotypically resistant or susceptible to Myobacterium avium subspecies paratuberculosis infection. Developmental & Comparative Immunology, 40(2), 210-217. doi: 10.1016/j.dci.2013.02.004
O'Brien, R., Hughes, A., Liggett, S., & Griffin, F. (2013). Composite testing for ante-mortem diagnosis of Johne's disease in farmed New Zealand deer: Correlations between bacteriological culture, histopathology, serological reactivity and faecal shedding as determined by quantitative PCR. BMC Veterinary Research, 9, 72. doi: 10.1186/1746-6148-9-72
Dobson, B., Liggett, S., O'Brien, R., & Griffin, J. F. T. (2013). Innate immune markers that distinguish red deer (Cervus elaphus) selected for resistant or susceptible genotypes for Johne’s disease. Veterinary Research, 44(1), 5. doi: 10.1186/1297-9716-44-5
Conference Contribution - Published proceedings: Abstract
Brennan, L., O'Brien, R., & Griffin, F. (2013). Genetic markers for resilience and susceptibility to Johne's disease in red deer (Cervus elaphus). Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 143). Retrieved from http://www.asi2013.org/
Griffin, F., O'Brien, R., Liggett, S., Marfell, B., Brennan, L., & Mackintosh, C. (2013). A deer model: Using a systems biology approach to study pathways of resilience or susceptibility to Johne's disease. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 80). Retrieved from http://www.asi2013.org/
2012
Conference Contribution - Published proceedings: Abstract
Griffin, J. F. T., O'Brien, R., Liggett, S., Dobson, B., & Mackintosh, C. G. (2012). Genetic markers for resistance and susceptibility to Johne's disease: A deer model. Proceedings of the 11th International Colloquium on Paratuberculosis (ICP). (pp. 99). Retrieved from http://www.paratuberculosis.info/
Dobson, B., O'Brien, R., & Griffin, F. (2012). The search for candidate genes that characterise susceptibility or resistance to Mycobacterium avium subspecies paratuberculosis. Proceedings of the 11th International Colloquium on Paratuberculosis (ICP). (pp. 92-93). Retrieved from http://www.paratuberculosis.info/
Dobson, B., O'Brien, R., & Griffin, J. F. T. (2012). The search for candidate genes that characterise susceptibility or resistance to pathogenic mycobacteria. Immunology, 137(Suppl. s1), (pp. 666). doi: 10.1111/imm.12002
2011
Journal - Research Article
Robinson, M. W., O'Brien, R., Mackintosh, C. G., Clark, R. G., & Griffin, J. F. T. (2011). Immunoregulatory cytokines are associated with protection from immunopathology following Mycobacterium avium subspecies paratuberculosis infection in red deer. Infection & Immunity, 79(5), 2089-2097. doi: 10.1128/IAI.00779-10
Conference Contribution - Published proceedings: Full paper
O'Brien, R., Hughes, A., & Griffin, F. (2011). Quantitative PCR as an ancillary, ante-mortem diagnostic test for Johne's disease in deer: A comparison between bacteriologic culture, serological reactivity and faecal shedding. In P. Wilson (Ed.), Proceedings of a Deer Course for Veterinarians No. 28. (pp. 121-127). Wellington, New Zealand: Deer Branch, New Zealand Veterinary Association. [Full Paper]
Conference Contribution - Published proceedings: Abstract
Griffin, F., Liggett, S., Dobson, B., O'Brien, R., Robinson, M., & Mackintosh, C. (2011). Genotypic and phenotypic markers for heritable resistance to mycobacteria in farmed deer. Proceedings of the Centre for Reproduction and Genomics Third Annual Research Colloquium. (pp. 4). Retrieved from http://www.crg.org.nz/colloquium/programme-2011.pdf
2010
Journal - Research Article
Gillan, S., Hughes, A. D., O'Brien, R., & Griffin, J. F. T. (2010). Ovine immune parameters following immunisation against Mycobacterium avium ssp. paratuberculosis using a lipid-based live cell vaccine. Veterinary Immunology & Immunopathology, 137(1-2), 109-119. doi: 10.1016/j.vetimm.2010.04.020
Robinson, M. W., O'Brien, R., Mackintosh, C. G., & Griffin, J. F. T. (2010). Peripheral blood mononuclear cell population changes associated with age and Mycobacterium avium subspecies paratuberculosis infection in red deer (Cervus elaphus). Veterinary Immunology & Immunopathology, 136(3-4), 211-218. doi: 10.1016/j.vetimm.2010.03.009
Gillan, S., O'Brien, R., Hughes, A. D., & Griffin, J. F. T. (2010). Identification of immune parameters to differentiate disease states among sheep infected with Mycobacterium avium subsp paratuberculosis. Clinical & Vaccine Immunology, 17(1), 108-117. doi: 10.1128/CVI.00359-09
Conference Contribution - Published proceedings: Full paper
O'Brien, R., Hughes, A., & Griffin, F. (2010). Quantitative PCR as an ancillary, ante-mortem diagnostic test for Johne's disease in deer. In P. Wilson (Ed.), Proceedings of a Deer Course for Veterinarians No. 27. (pp. 45-51). Wellington, New Zealand: Deer Branch, New Zealand Veterinary Association. [Full Paper]
Conference Contribution - Published proceedings: Abstract
Griffin, F., Liggett, S., Dobson, B., O'Brien, R., Robinson, M., & Mackintosh, C. (2010). Heritable resistance and susceptibility to pathogenic Mycobacteria: A deer model. Proceedings of the 3rd Annual Otago International Health Research Network [OIHRN] Conference. (pp. 21-22). Retrieved from http://dnmeds.otago.ac.nz/departments/psm/research/international_hlth/conference/programme.html
2009
Conference Contribution - Published proceedings: Full paper
O'Brien, R., Hughes, A., & Griffin, F. (2009). Quantitative PCR as an ancillary, ante-mortem diagnostic test for Johne's disease in deer. In P. Wilson (Ed.), Proceedings of a Deer Course for Veterinarians No. 26. (pp. 62-66). Wellington, New Zealand: Deer Branch, New Zealand Veterinary Association. [Full Paper]
Conference Contribution - Published proceedings: Abstract
Griffin, F., O'Brien, R., Liggett, S., & Mackintosh, C. (2009). A deer model for heritable resistance to MAP infection and Johne's disease. Proceedings of the 10th International Colloquium on Paratuberculosis (ICP). (pp. 288). Retrieved from http://www.paratuberculosis.info/
Robinson, M. W., O'Brien, R., & Griffin, F. (2009). Interleukin 17 and interleukin 23 gene expression differentiate severe pathology in Johne's disease. Proceedings of the 10th International Colloquium on Paratuberculosis (ICP). (pp. 119). Retrieved from http://www.paratuberculosis.info/
Robinson, M. W., O'Brien, R., & Griffin, F. (2009). Interleukin 17 and interleukin 23 gene expression differentiate severe pathology in Johne's disease. Proceedings of the Australasian Society for Immunology 39th Annual Scientific Meeting. ASI. Retrieved from http://www.asi2009.org/
Griffin, F., Liggett, S., O'Brien, R., & Mackintosh, C. (2009). Paratuberculosis in deer: A large animal model for heritable resistance to pathogenic mycobacteria. Proceedings of the Webster Centre for Infectious Diseases Symposium. WCID. Retrieved from http://www.webstercentre.otago.ac.nz/WCIDSymposiumProgramme.pdf
Robinson, M. W., O'Brien, R., & Griffin, J. F. T. (2009). Gene expression profiles differentiate pathological outcomes of Johne's disease: An infectious model of inflammatory bowel disease. Proceedings of the Webster Centre for Infectious Diseases Symposium. WCID. Retrieved from http://www.webstercentre.otago.ac.nz/WCIDSymposiumProgramme.pdf
Conference Contribution - Poster Presentation (not in published proceedings)
Robinson, M., O'Brien, R., & Griffin, F. (2009, September). The pro-inflammatory genes interleukin 17 and interleukin 23 are associated with severe pathology and clinical Johne's disease. Poster session presented at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand.
2008
Journal - Research Article
Robinson, M., O'Brien, R., Mackintosh, C., & Griffin, F. (2008). Differential immune responses of red deer (Cervus elaphus) following experimental challenge with Mycobacterium avium subsp. paratuberculosis. Clinical & Vaccine Immunology, 15(6), 963-969. doi: 10.1128/CVI.00031-08
Conference Contribution - Verbal presentation and other Conference outputs
Robinson, M., O'Brien, R., Mackintosh, C., & Griffin, F. (2008, November). Immunopathology and bacterial load in the intestinal tract during Johne's disease. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.
Griffin, F., Rodgers, C., O'Brien, R., Robinson, M., & Liggett, S. (2008, November). A deer model of chronic inflammatory bowel disease (CIBD) that mimics Crohn's disease in humans. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.
2006
Journal - Research Article
O'Brien, R., Mackintosh, C. G., Bakker, D., Kopecna, M., Pavlik, I., & Griffin, J. F. T. (2006). Immunological and molecular characterization of susceptibility in relationship to bacterial strain differences in Mycobacterium avium subsp. paratuberculosis infection in the red deer (Cervus elaphus). Infection & Immunity, 74(6), 3530-3537.
2005
Journal - Research Article
Begg, D. J., O'Brien, R., Mackintosh, C. G., & Griffin, J. F. T. (2005). Experimental infection model for Johne's disease in sheep. Infection & Immunity, 73(9), 5603-5611.
Conference Contribution - Poster Presentation (not in published proceedings)
Turner, D. J., O'Brien, R., Rodgers, C. R., & Griffin, J. F. T. (2005, August). Comparative pathology of Johne's disease in deer and sheep. Poster session presented at the 8th International Colloquium on Paratuberculosis, Copenhagen, Denmark.
2004
Conference Contribution - Published proceedings: Full paper
O'Brien, R., Rodgers, C., Liggett, S., Spittle, E., Crosbie, P., & Griffin, J. F. T. (2004). Immunodiagnosis of TB and Johne's disease in deer. In P. R. Wilson (Ed.), Proceedings of the 1st World Deer Veterinary Congress: Deer Branch of the New Zealand Veterinary Association. (pp. 102-105). Palmerston North, New Zealand: Institute of Veterinary, Animal & Biomedical Sciences, Massey University. [Full Paper]
Griffin, J. F. T., O'Brien, R., & Rodgers, C. (2004). Johne's disease and Crohn's disease: Implications for New Zealand farming. Proceedings of the Food Safety & Biosecurity Branch of the New Zealand Veterinary Association: Publication no. 239. (pp. 1-6). Palmerston North, New Zealand: VetLearn Foundation. [Full Paper]
2003
Conference Contribution - Published proceedings: Full paper
Griffin, J. F. T., O'Brien, R. P., Spittle, E., Liggett, S., Cooper, M., Crosbie, P., & Rodgers, C. (2003). Immunodiagnostic tests in the management of Johne's disease in deer herds. Proceedings of the Deer Branch New Zealand Veterinary Association. 20, (pp. 99-102). [Full Paper]
O'Brien, R. P., Chinn, N., Rodgers, C., Liggett, S., Spittle, E., Crosbie, P., … Griffin, J. F. T. (2003). Johne's disease: An emerging problem in farmed deer. Proceedings of the Seventh International Colloquium on Paratuberculosis. (pp. 353-357). [Full Paper]
2002
Conference Contribution - Published proceedings: Full paper
O'Brien, R. P., Chinn, N., Rodgers, C., Liggett, S., Spittle, E., Mackintosh, C. G., … Griffin, J. F. T. (2002). Demystifying Johne's disease in deer. Proceedings of the New Zealand Veterinary Association: Deer Branch. 19, (pp. 13-18). Palmerston North: Massey University Press. [Full Paper]
2001
Journal - Research Article
Cameron, H., O'Brien, R., Murray, A. S., Cryan, B., Hone, R., & Rogers, M. (2001). Evaluation of the micobacterium bovis restriction fragment length polymorphism probe pUCD, in combination with the direct repeat probe, for molecular typing of mycobacterium tuberculosis strains in Ireland. Journal of Clinical Microbiology, 39(12), 4404-4406.
2000
Journal - Research Article
O'Brien, R., Flynn, O., Costello, E., O'Grady, D., & Rogers, M. (2000). Identification of a novel DNA probe for strain typing Mycobacterium bovis by restriction fragment length polymorphism analysis. Journal of Clinical Microbiology, 38(5), 1723-1730.
O'Brien, R., Danilowicz, B., Bailey, L., Flynn, O., Costello, E., O'Grady, D., & Rogers, M. (2000). Characterization of the Mycobacterium bovis restriction fragment length polymorphism DNA probe pUCD and performance comparison with standard methods. Journal of Clinical Microbiology, 38(9), 3362-3369.
Awarded Doctoral Degree
O'Brien, R. P. (2000). Strain typing of Mycobacterium bovis in Ireland: The identification, characterisation and performance, evaluation of a novel, polymorphic, mycobacterial genetic marker (PhD). University College Dublin, Dublin, Ireland.
1999
Journal - Research Article
Costello, E., O'Grady, D., Flynn, O., O'Brien, R., Rogers, M., Quigley, F., … Griffin, J. (1999). Study of restriction fragment length polymorphism analysis and spoligotyping for epidemiological investigation of Mycobacterium bovis infection. Journal of Microbiology, 37(10), 3217-3222.
1998
Journal - Professional & Other Non-Research Articles
Costello, E., O'Grady, D., O'Brien, R., Flynn, O., Rogers, M., Quigley, F., … Griffin, J. F. T. (1998). Strain typing of mycobacterium bovis isolates. Irish Veterinary Journal, 51(3), 133.
