2023
Chapter in Book - Research
Torbati, E., Stuart, G., Krause, K., Brown, C., & Wise, L. (2023). Methods to assess chemokine binding and anti-chemotactic activity of virus proteins. In A. R. Lucas (Ed.), Chemokine-glycosaminoglycan interactions: Methods and protocols: Methods in molecular biology (Vol. 2597). (pp. 217-234). New York, N Y: Humana Press. doi: 10.1007/978-1-0716-2835-5_16
Journal - Research Article
Kok, J. M. L., Dowd, G. C., Cabral, J. D., & Wise, L. M. (2023). Macrocystis pyrifera lipids reduce cytokine-induced pro-inflammatory signalling and barrier dysfunction in human keratinocyte models. International Journal of Molecular Sciences, 24, 1638. doi: 10.3390/ijms242216383
Journal - Research Other
McInnes, C. J., Damon, I. K., Smith, G. L., McFadden, G., Isaacs, S. N., Loper, R. L., … Wise, L. M., & Lefkowitz, E. J. (2023). ICTV Virus taxonomy profile: Poxviridae 2023. Journal of General Virology, 104, 001849. doi: 10.1099/jgv.0.001849
Conference Contribution - Published proceedings: Abstract
Kok, J. M. L., Dowd, G. C., Cabral, J. D., & Wise, L. (2023). Investigating the effects of an omega-3 rich brown seaweed extract on atopic dermatitis in a keratinocytes raft model. Journal of Investigative Dermatology, 143, (pp. S334). doi: 10.1016/j.jid.2023.09.016
Conference Contribution - Verbal presentation and other Conference outputs
Stent, H. R. T., Cumming, M. H., Dowd, G. C., & Wise, L. M. (2023, August). Biocompatible cross-linking of marine collagen nanofibers for tissue engineering. Verbal presentation at the 267th Otago Medical School Research Society (OMSRS) Meeting: PhD Student Speaker Awards, Dunedin, New Zealand.
2022
Journal - Research Article
Naqash, A., Stuart, G., Kemp, R., & Wise, L. (2022). Parapoxvirus interleukin-10 homologues vary in their receptor binding, anti-inflammatory, and stimulatory activities. Pathogens, 11, 507. doi: 10.3390/pathogens11050507
Kok, J. M. L., Dowd, G., Cabral, J., & Wise, L. (2022). Time-dependent anti-inflammatory effects of a lipid extract from Macrocystis pyrifera on toll-like receptor 2 signaling in human THP-1 monocytes. Planta Medica International Open, 9, e80-e89. doi: 10.1055/a-1729-3654
Conference Contribution - Published proceedings: Abstract
Schwass, C. M., Stuart, G. S., Highton, A. J., & Wise, L. M. (2022). Raji and Daudi B cell-lines are not appropriate models of blood-derived B cell responses to interleukin-10. In L. Wilson, H. Harcombe, P. Jayakaran, L. Burga, J. Antony, K. Morgaine, M. Garelja, A. Middleton, M. Anwar & T. Milne (Eds.), Proceedings of the 264th Otago Medical School Research Society (OMSRS) Meeting: Masters/Honours Student Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
Berry-Kilgour, C. R. H., Oey, I., Cabral, J. D., Dowd, G. C., & Wise, L. M. (2022). Decellularised seaweed as a novel biomaterial for treatment of skin wounds. In L. Wilson, H. Harcombe, P. Jayakaran, L. Burga, J. Antony, K. Morgaine, M. Garelja, A. Middleton, M. Anwar & T. Milne (Eds.), Proceedings of the 263rd Otago Medical School Research Society (OMSRS) Meeting: PhD Student Speaker Awards. Dunedin, New Zealand: OMSRS. Retrieved from https://ourarchive.otago.ac.nz/handle/10523/12839
Longoni, A., Major, G., Atienza-Roca, P., Wise, L., Hooper, G., Kieser, D., Woodfield, T., … Lim, K. (2022). Gelatin incorporation in VEGF-loaded PVA-Tyramine hydrogels to enhance cellular interaction and vascular infiltration. Tissue Engineering Part A, 28(Suppl. 3), (pp. 642). doi: 10.1089/ten.tea.2022.29036.abstracts
2021
Chapter in Book - Research
Stuart, G. S., Jones, N. C., & Wise, L. M. (2021). Murine model of thermal burn injury for evaluating protein therapeutics derived from viruses. In A. R. Lucas (Ed.), Viruses as therapeutics: Methods and protocols: Methods in molecular biology (Vol. 2225). (pp. 93-105). New York, NY: Humana Press. doi: 10.1007/978-1-0716-1012-1_6
Journal - Research Article
Hazlett, J., Niemi, V., Aiderus, A., Powell, K., Wise, L., Kemp, R., & Dunbier, A. K. (2021). Oestrogen deprivation induces chemokine production and immune cell recruitment in in vitro and in vivo models of oestrogen receptor-positive breast cancer. Breast Cancer Research, 23, 95. doi: 10.1186/s13058-021-01472-1
Longoni, A., Li, J., Lindberg, G. C. J., Rnjak-Kovacina, J., Wise, L. M., Hooper, G. J., Woodfield, T. B. F., Kieser, D. C., & Lim, K. S. (2021). Strategies for inclusion of growth factors into 3D printed bone grafts. Essays in Biochemistry, 65(3), 569-585. doi: 10.1042/ebc20200130
Journal - Research Other
Rajesh, A., Stuart, G., Real, N., Tschirley, A., Ahn, J., Wise, L., & Hibma, M. (2021). Skin antigen presenting cells and wound healing: New knowledge gained and challenges encountered using mouse depletion models. Immunology, 163, 98-104. doi: 10.1111/imm.13311
Berry-Kilgour, C., Cabral, J., & Wise, L. (2021). Advancements in the delivery of growth factors and cytokines for the treatment of cutaneous wound indications [Invited]. Advances in Wound Care, 10(11), 596-622. doi: 10.1089/wound.2020.1183
Conference Contribution - Published proceedings: Abstract
Tabi-Amponsah, A. D., Stuart, G. S., Kemp, R. A., & Wise, L. M. (2021). Dissecting the receptor signalling events responsible for the immune suppressive and immune stimulatory effects of IL-10. New Zealand Medical Journal, 134(1547), (pp. 144). Retrieved from https://www.nzma.org.nz/journal
Machado, A. A., Stuart, G. S., Lim, K. S., & Wise, L. M. (2021). Evaluation of vascular endothelial growth factor-A165 glycoforms in angiogenic assays. New Zealand Medical Journal, 134(1547), (pp. 144). Retrieved from https://www.nzma.org.nz/journal
Naqash, A., Kemp, R., Glass, M., & Wise, L. (2021). Control of immune cell function by IL-10 proteins derived from viruses. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 46). [Abstract]
McCrostie, C. B. M., & Wise, L. (2021). Characterisation of the inflammatory response to injury in an ex vivo rodent model of spinal cord injury. New Zealand Medical Journal, 134(1537), (pp. 108). Retrieved from https://www.nzma.org.nz/journal
Cao, H., Stitely, M., & Wise, L. (2021). Investigating the wound healing capacity of subcutaneous adipose tissue. New Zealand Medical Journal, 134(1535), (pp. 99). Retrieved from https://www.nzma.org.nz/journal
Stent, H. R. T., & Wise, L. M. (2021). Inflammation and scarring in an ex vivo model of spinal cord injury. New Zealand Medical Journal, 134(1535), (pp. 97). Retrieved from https://www.nzma.org.nz/journal
Conference Contribution - Verbal presentation and other Conference outputs
Wise, L. (2021, November). Algal lipids for treatment of skin inflammation & barrier dysfunction. Verbal presentation at the Australasian Wound and Tissue Repair Society (AWTRS) Wound Healing Symposium, [Online].
2020
Journal - Research Article
Bose, D., Banerjee, S., Singh, R. K., Wise, L. M., & Robertson, E. S. (2020). Vascular endothelial growth factor encoded by Parapoxviruses can regulate metabolism and survival of triple negative breast cancer cells. Cell Death & Disease, 11, 996. doi: 10.1038/s41419-020-03203-4
Wise, L. M., Stuart, G. S., Sriutaisuk, K., Adams, B. R., Riley, C. B., & Theoret, C. L. (2020). Anti-fibrotic actions of equine interleukin-10 on transforming growth factor-beta1-simulated dermal fibroblasts isolated form limbs of horses. Frontiers in Veterinary Science, 7, 577835. doi: 10.3389/fvets.2020.577835
Atienza-Roca, P., Kieser, D., Cui, X., Bathish, B., Ramaswamy, Y., Hooper, G. J., Clarkson, A. N., … Wise, L. M., Woodfield, T. B. F., & Lim, K. S. (2020). Visible light mediated PVA-tyramine hydrogels for covalent incorporation and tailorable release of functional growth factors. Biomaterials Science, 8(18), 5005-5019. doi: 10.1039/D0BM00603C
Rajesh, A., Stuart, G., Real, N., Ahn, J., Tschirley, A., Wise, L., & Hibma, M. (2020). Depletion of langerin+ cells enhances cutaneous wound healing. Immunology, 160, 366-381. doi: 10.1111/imm.13202
Wise, L. M., Stuart, G. S., Jones, N. C., Fleming, S. B., & Mercer, A. A. (2020). Orf virus IL-10 and VEGF-E act synergistically to enhance healing of cutaneous wounds in mice. Journal of Clinical Medicine, 9(4), 1085. doi: 10.3390/jcm9041085
Journal - Research Other
Yaron, J. R., Zhang, L., Guo, Q., Burgin, M., Schutz, L. N., Awo, E., Wise, L., … Lucas, A. R. (2020). Deriving immune modulating drugs from viruses: A new class of biologics. Journal of Clinical Medicine, 9(4), 972. doi: 10.3390/jcm9040972
2019
Journal - Research Article
Sharif, S., Ueda, N., Nakatani, Y., Wise, L. M., Clifton, S., Lateef, Z., Mercer, A. A., & Fleming, S. B. (2019). Chemokine-binding proteins encoded by parapoxvirus of red deer of New Zealand display evidence of gene duplication and divergence of ligand specificity. Frontiers in Microbiology, 10, 1421. doi: 10.3389/fmicb.2019.01421
Lateef, Z., Stuart, G., Jones, N., Mercer, A., Fleming, S., & Wise, L. (2019). The cutaneous inflammatory response to thermal burn injury in a murine model. International Journal of Molecular Sciences, 20(3), 538. doi: 10.3390/ijms20030538
Journal - Research Other
Rajesh, A., Wise, L., & Hibma, M. (2019). The role of Langerhans cells in pathologies of the skin. Immunology & Cell Biology, 97(8), 700-713. doi: 10.1111/imcb.12253
Conference Contribution - Published proceedings: Abstract
Rajesh, A., Stuart, G. S., Real, N., Tschirley, A., Wise, L., & Hibma, M. (2019). Novel suppressive role of Langerhans cells in wound healing. European Journal of Immunology, 49(Suppl. 2), (pp. 22-23). doi: 10.1002/eji.201970200
McBride, T., Lateef, Z., & Wise, L. (2019). The role of macrophages in allogenic skin graft rejection in murine models. New Zealand Medical Journal, 132(1499), (pp. 86). Retrieved from https://www.nzma.org.nz/journal
Conference Contribution - Verbal presentation and other Conference outputs
Cabral, J. D., Murray, E., Turner, P., & Wise, L. (2019, August-September). Wound healing biomaterials as cell and drug delivery vehicles. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2018
Journal - Research Article
Wise, L. M., Bodaan, C. J., Stuart, G. S., Real, N. C., Lateef, Z., Mercer, A. A., … Theoret, C. L. (2018). Treatment of limb wounds of horses with orf virus IL-10 and VEGF-E accelerates resolution of exuberant granulation tissue, but does not prevent its development. PLoS ONE, 13(5), e0197223. doi: 10.1371/journal.pone.0197223
Wise, L. M., Stuart, G. S., Real, N. C., Fleming, S. B., & Mercer, A. A. (2018). VEGF receptor-2 activation mediated by VEGF-E limits scar tissue formation following cutaneous injury. Advances in Wound Care, 7(8), 283-297. doi: 10.1089/wound.2016.0721
Journal - Research Other
Lateef, Z., & Wise, L. M. (2018). Exploitation of receptor tyrosine kinases by viral-encoded growth factors. Growth Factors, 36(3-4), 118-140. doi: 10.1080/08977194.2018.1520229
Conference Contribution - Poster Presentation (not in published proceedings)
Rajesh, A., Jones, N., Stuart, G., Cunliffe, H., Wise, L., & Hibma, M. (2018, September). Investigating the role of Langerhans cells during wound healing. Poster session presented at the Otago Spotlight Symposium on Infectious Disease, Wellington, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Wise, L. (2018, April). Hydrogel delivery of orf virus proteins VEGF-E and IL-10 enhances the resolution of exuberant granulation tissue in horses. Verbal presentation at the University of Otago Centre for Bioengineering & Nanomedicine Symposium: Biomaterials and Regenerative Medicine, Dunedin, New Zealand.
Lateef, Z., Jones, N. C., Stuart, G. S., & Wise, L. M. (2018, August). Improved healing and scar quality in surgical wounds following treatment with a viral protein combination. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Rajesh, A., Stuart, G., Real, N., Ahn, J., Tschirley, A., Hibma, M., & Wise, L. (2018, August). Depletion of Langerin/CD207+ cells accelerated wound healing. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.
Other Research Output
Wise, L. (2018, September). Improved C-section healing: Translation of a biological therapy. Department of Women's & Children's Health, University of Otago, Dunedin, New Zealand. [Department Seminar].
2017
Journal - Research Article
Fleming, S. B., McCaughan, C., Lateef, Z., Dunn, A., Wise, L. M., Real, N. C., & Mercer, A. A. (2017). Deletion of the chemokine binding protein gene from the Parapoxvirus Orf virus reduces virulence and pathogenesis in sheep. Frontiers in Microbiology, 8, 46. doi: 10.3389/fmicb.2017.00046
Conference Contribution - Published proceedings: Abstract
Burgess, E., Real, N., & Wise, L. (2017). Development of a new in vitro skin infection model to assess topical antivirals against Molluscum contagiosum virus. New Zealand Medical Journal, 130(1461), (pp. 90). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Verbal presentation and other Conference outputs
Rajesh, A., Cunliffe, H., Wise, L., & Hibma, M. (2017, July). Role of Langerhans cells in wound healing. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.
Dunbier, A., Hazlett, J., Wise, L., & Kemp, R. (2017, July). Effect of oestrogen deprivation on chemokine expression and immune cell recruitment in breast cancer. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.
2016
Journal - Research Article
Sharif, S., Nakatani, Y., Wise, L., Corbett, M., Real, N. C., Stuart, G. S., Lateef, Z., Krause, K., Mercer, A. A., & Fleming, S. B. (2016). A broad-spectrum chemokine-binding protein of bovine papular stomatitis virus inhibits neutrophil and monocyte infiltration in inflammatory and wound models of mouse skin. PLoS ONE, 11(12), e0168007. doi: 10.1371/journal.pone.0168007
Bodaan, C. J., Wise, L. M., Wakelin, K. A., Stuart, G. S., Real, N. C., Mercer, A. A., … Theoret, C. (2016). Short-term treatment of equine wounds with orf virus IL-10 and VEGF-E dampens inflammation and promotes repair processes without accelerating closure. Wound Repair & Regeneration, 24(6), 966-980. doi: 10.1111/wrr.12488
Wakelin, K. A., Wise, L. M., Bodaan, C. J., Mercer, A. A., Riley, C. B., & Theoret, C. L. (2016). Orf virus interleukin-10 and vascular endothelial growth factor-E modulate gene expression in cultured equine dermal fibroblasts. Veterinary Determatology, 27(5), 434-438. doi: 10.1111/vde.12370
Bennett, J. R., Lateef, Z., Fleming, S. B., Mercer, A. A., & Wise, L. M. (2016). Orf virus IL-10 reduces monocyte, dendritic cell and mast cell recruitment to inflamed skin. Virus Research, 213, 230-237. doi: 10.1016/j.virusres.2015.12.015
Conference Contribution - Published proceedings: Abstract
Wise, L., Libuda, F., Real, N., Stuart, G., Wilkins, S., Wakelin, K., Mercer, A., Clarkson, A., Walker, G., … Theoret, C. (2016). Combined delivery of orf virus proteins VEGF-E and IL-10 dampens inflammation and promotes repair processes in equine skin wounds. Proceedings of the Diagnostics, Drugs, Devices, Discovery (D4) Conference. Retrieved from http://www.otago.ac.nz/d4/index.html
Intellectual Property
Wise, L. M., Fleming, S. B., & Mercer, A. A. (2016). Combination treatments and compositions for wound healing comprising viral VEGF. (9,314,505). United States.
2015
Journal - Research Article
Harvey, R., McCaughan, C., Wise, L. M., Mercer, A. A., & Fleming, S. B. (2015). Orf virus inhibits interferon stimulated gene expression and modulates the JAK/STAT signalling pathway. Virus Research, 208, 180-188. doi: 10.1016/j.virusres.2015.06.014
Couñago, R. M., Knapp, K. M., Nakatani, Y., Fleming, S. B., Corbett, M., Wise, L. M., Mercer, A. A., & Krause, K. L. (2015). Structures of orf virus chemokine binding protein in complex with host chemokines reveal clues to broad binding specificity. Structure, 23(7), 1199-1213. doi: 10.1016/j.str.2015.04.023
Fleming, S. B., Wise, L. M., & Mercer, A. A. (2015). Molecular genetic analysis of Orf virus: A poxvirus that has adapted to skin. Viruses, 7(3), 1505-1539. doi: 10.3390/v7031505
Lee, S., Chu, H. X., Kim, H. A., Real, N. C., Sharif, S., Fleming, S. B., Mercer, A. A., Wise, L. M., … Sobey, C. G. (2015). Effect of a broad-specificity chemokine-binding protein on brain leukocyte infiltration and infarct development. Stroke, 46, 537-544. doi: 10.1161/strokeaha.114.007298
Conference Contribution - Verbal presentation and other Conference outputs
Dunbier, A. K., Hazlett, J. A., Hunter, B. L., Buchanan, S. T., Bundock, A. S., Wise, L. M., Kemp, R. A., & Dowsett, M. (2015, August-September). Determinants of resistance to endocrine therapy in breast cancer. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Wise, L., Wong, K., Wati, U., Mros, S., Fleming, J., Weerasinghe, R., Brooks, H., & McConnell, M. (2015, August-September). Emerging antimicrobial therapies for skin wound infections. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2014
Journal - Research Article
Wise, L. M., Stuart, G. S., Real, N. C., Fleming, S. B., & Mercer, A. A. (2014). Orf virus IL-10 accelerates wound healing while limiting inflammation and scarring. Wound Repair & Regeneration, 22(3), 356-367. doi: 10.1111/wrr.12169
Conference Contribution - Published proceedings: Abstract
Sobey, C., Lee, S., Chu, H., Kim, H. A., Drummond, G., & Wise, L. (2014). Using a chemokine binding protein to treat acute stroke. International Journal of Stroke, 9(Suppl. 3), (pp. 188). doi: 10.1111/ijs.12367
Menorca, A., Mros, S., Brooks, H., Wise, L., & McConnell, M. (2014). Antiviral properties of natural extracts against herpes simplex virus type 1. New Zealand Medical Journal, 127(1406). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Poster Presentation (not in published proceedings)
Wilkins, S., Wise, L., Walker, G., Libuda, F., & Real, N. (2014, November). Engineering electrospun nanofibres with orf virus proteins for improved wound healing. Poster session presented at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.
2013
Conference Contribution - Published proceedings: Abstract
Ahn, J., Wise, L., Real, N., Stuart, G., & Hibma, M. (2013). Inhibitory role of Langerhans cells (LCs) during cutaneous wound healing. New Zealand Medical Journal, 126(1386). Retrieved from http://www.nzma.org.nz/journal
Wise, L. M., Real, N. C., Stuart, G. S., Fleming, S. B., & Mercer, A. A. (2013). ORF virus homologs of VEGF and IL-10 act synergistically to accelerate skin regeneration and limit scarring. Wound Repair & Regeneration, 21(2), (pp. A47). doi: 10.1111/wrr.12030
Conference Contribution - Verbal presentation and other Conference outputs
Wise, L. (2013, August). Exploiting the therapeutic potential of viruses. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2012
Journal - Research Article
Wise, L. M., Inder, M. K., Real, N. C., Stuart, G. S., Fleming, S. B., & Mercer, A. A. (2012). The vascular endothelial growth factor (VEGF)-E encoded by orf virus regulates keratinocyte proliferation and migration and promotes epidermal regeneration. Cellular Microbiology, 14(9), 1376-1390. doi: 10.1111/j.1462-5822.2012.01802.x
Conference Contribution - Published proceedings: Abstract
Wise, L., Stuart, G., Real, N., Fleming, S., & Mercer, A. (2012). VEGF-E enhances wound closure by promoting re-epithelialisation and reducing granulation tissue formation. Journal of Vascular Research, 49(Suppl. 1), (pp. 37). doi: 10.1159/000334223
Wise, L., Real, N., Inder, M., Fleming, S., & Mercer, A. (2012). Dissecting the role of the VEGF receptors in VEGF-induced monocyte activation and migration. Journal of Vascular Research, 49(Suppl. 1), (pp. 36). doi: 10.1159/000334223
Wise, L., Stuart, G., Real, N., Inder, M., Fleming, S., & Mercer, A. (2012). VEGF-E enhances wound closure by promoting vascular and epidermal regeneration while limiting granulation tissue formation. Wound Repair & Regeneration, 20(5), (pp. A78). doi: 10.1111/j.1524-475X.2012.00835.x
Wise, L., Stuart, G., Real, N., Inder, M., Fleming, S., & Mercer, A. (2012). Orf virus IL-10 enhances wound resolution by limiting inflammation and granualtion tissue formation. Wound Repair & Regeneration, 20(5), (pp. A69). doi: 10.1111/j.1524-475X.2012.00835.x
Conference Contribution - Verbal presentation and other Conference outputs
Krause, K., Couñago, R., Fleming, S., Corbett, M., Wise, L., Knapp, K., & Mercer, A. (2012, November). The structure of the chemokine binding protein from orf virus reveals clues to its broad binding specificity. Verbal presentation at the 57th New Zealand Microbiological Society (NZMS) Annual Scientific Meeting, Dunedin, New Zealand.
2011
Conference Contribution - Published proceedings: Abstract
D'Costa, Z., Matthews, C., Mercer, A., Wise, L., & Hibma, M. (2011). Human papillomavirus type 16 E6 regulates E-cadherin in a DNA methyltransferase-dependent manner. New Zealand Medical Journal, 124(1344). Retrieved from http://journal.nzma.org.nz/journal/124-1344/4919/content.pdf
Conference Contribution - Verbal presentation and other Conference outputs
Wise, L., Stuart, G., Real, N., Fleming, S., & Mercer, A. (2011, November-December). VEGF-E enhances wound closure by promoting re-epithelialisation and reducing granulation tissue formation. Verbal presentation at the 15th Australian and New Zealand Microcirculation Society (ANZMS) Meeting, Margaret River, Australia.
Wise, L., Real, N., Inder, M., Fleming, S., & Mercer, A. (2011, November-December). Dissecting the role of the VEGF receptors in VEGF-induced monocyte activation and migration. Verbal presentation at the 15th Australian and New Zealand Microcirculation Society (ANZMS) Meeting, Margaret River, Australia.
2010
Journal - Research Article
Lateef, Z., Baird, M. A., Wise, L. M., Young, S., Mercer, A. A., & Fleming, S. B. (2010). The chemokine binding protein encoded by the poxvirus orf virus inhibits recruitment of dendritic cells to sites of skin inflammation and migration to peripheral lymph nodes. Cellular Microbiology, 12(5), 665-676. doi: 10.1111/j.1462-5822.2009.01425.x
Other Research Output
Wise, L. (July, 2010). Viral vascular endothelial growth factor (VEGF): A multi-faceted virulence factor. University of Otago Department of Pharmacology & Toxicology Seminar , Dunedin, New Zealand. [Department Seminar].
2009
Journal - Research Article
Lateef, Z., Baird, M. A., Wise, L. M., Mercer, A. A., & Fleming, S. B. (2009). Orf virus-encoded chemokine-binding protein is a potent inhibitor of inflammatory monocyte recruitment in a mouse skin model. Journal of General Virology, 90(6), 1477-1482. doi: 10.1099/vir.0.009589-0
Deane, D., Ueda, N., Wise, L. M., Wood, A. R., Percival, A., Jepson, C., … Fleming, S. B., Mercer, A. A., & McInnes, C. J. (2009). Conservation and variation of the parapoxvirus GM-CSF-inhibitory factor (GIF) proteins. Journal of General Virology, 90, 970-977. doi: 10.1099/vir.0.006692-0
Conference Contribution - Published proceedings: Abstract
Inder, M., Dryden, N., Mercer, A., Fleming, S., & Wise, L. (2009). VEGF-E induces keratinocyte proliferation and migration via VEGFR-2. Journal of Vascular Research, 46(Suppl. 2), (pp. 30). doi: 10.1159/000230992
Corbett, M., Real, N., Fleming, S., Mercer, A., & Wise, L. (2009). Natural variation in ligand binding by parapoxvirus chemokine binding proteins. Journal of Vascular Research, 46(Suppl. 2), (pp. 28). doi: 10.1159/000230992
Wise, L., Li, K., van de Vrie, M., Real, N., Fleming, S., & Mercer, A. (2009). Regulation of dendritic cell function by a viral vascular endothelial growth factor. Journal of Vascular Research, 46(Suppl. 2), (pp. 20). doi: 10.1159/000230992
Corbett, M., Real, N., Fleming, S., Mercer, A., & Wise, L. (2009). The orf virus chemokine binding protein is a novel broad-spectrum chemokine inhibitor. New Zealand Medical Journal, 122(1306). Retrieved from http://journal.nzma.org.nz/journal/122-1306/3899/content.pdf
Inder, M., Dryden, N., Mercer, A., Fleming, S., & Wise, L. (2009). VEGF-E induces keratinocyte proliferation and migration via VEGFR-2. In C. Matthewson & M. Taumoepeau (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices VI. (pp. 25). Dunedin, New Zealand: Pacific Islands Centre, University of Otago. [Abstract]
Conference Contribution - Edited volume of conference proceedings
Sandow, S. L., & Wise, L. (Eds.). (2009). Journal of Vascular Research, 46(Suppl. 2). 43p. doi: 10.1159/000230992
Conference Contribution - Poster Presentation (not in published proceedings)
Inder, M., Dryden, N., Mercer, A., Fleming, S., & Wise, L. (2009, September). VEGF induces keratinocyte proliferation and migration via VEGFR-2. Poster session presented at the Third Annual Division of Health Sciences Research Forum, Wellington, New Zealand.
2008
Journal - Research Article
Inder, M. K., Wise, L. M., Fleming, S. B., & Mercer, A. A. (2008). The C-terminus of viral vascular endothelial growth factor-E partially blocks binding to VEGF receptor-1. FEBS Journal, 275(1), 207-217. doi: 10.1111/j.1742-4658.2007.06189.x
Conference Contribution - Published proceedings: Abstract
Inder, M., Dryden, N., Mercer, A., Fleming, S., & Wise, L. (2008). VEGF-E induces keratinocyte proliferation and migration via VEGFR-2. In C. Matthewson & M. Taumoepeau (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices V. (pp. 21). Dunedin, New Zealand: Pacific Islands Centre, University of Otago. [Abstract]
Lateef, Z., Baird, M., Wise, L., Mercer, A., & Fleming, S. (2008). The characterisation of orf virus chemokine binding protein using murine models. New Zealand Medical Journal, 121(1278). Retrieved from http://journal.nzma.org.nz/journal/121-1278/3179/content.pdf
2007
Journal - Research Article
Wise, L. M., Savory, L. J., Dryden, N. H., Whelan, E. M., Fleming, S. B., & Mercer, A. A. (2007). Major amino acid sequence variants of viral vascular endothelial growth factor are functionally equivalent during Orf virus infection of sheep skin. Virus Research, 128, 115-125.
Inder, M. K., Ueda, N., Mercer, A. A., Fleming, S. B., & Wise, L. M. (2007). Bovine papular stomatitis virus encodes a functionally distinct VEGF that binds both VEGFR-1 and VEGFR-2. Journal of General Virology, 88, 781-791.
Ueda, N., Inder, M. K., Wise, L. M., Fleming, S. B., & Mercer, A. A. (2007). Parapoxvirus of red deer in New Zealand encodes a variant of viral vascular endothelial growth factor. Virus Research, 124, 50-58.
Wise, L., McCaughan, C., Tan, C. K., Mercer, A. A., & Fleming, S. B. (2007). Orf virus interleukin-10 inhibits cytokine synthesis in activated human THP-1 monocytes, but only partially impairs their proliferation. Journal of General Virology, 88, 1677-1682.
Conference Contribution - Published proceedings: Abstract
Inder, M. K., Wise, L. M., Fleming, S. B., & Mercer, A. A. (2007). The conserved O-glycosylated C-terminus of the Parapoxvirus VEGF family member, ORFVNZ2VEGF, plays a role in its unique receptor-binding profile. In C. Matthewson & M. Taumoepeau (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices IV. (pp. 19). Dunedin, New Zealand: Pacific Islands Centre, University of Otago. [Abstract]
2006
Intellectual Property
Wise, L. M., Mercer, A. A., Savory, L. J., & Fleming, S. B. (2006). Vascular endothelial growth factor-like protein from ORF virus NZ10 binds and activates mammalian VEGF receptor-2. (EP 1 126 863).
2005
Conference Contribution - Published proceedings: Abstract
Wise, L. M., McCaughan, C. A., Lateef, Z. I., Inder, M. K., Mercer, A. A., & Fleming, S. B. (2005). Manipulation of immune cell migration and pro-inflammatory cytokine expression by Orf virus-encoded virulence factors. Inflammatory Research. 54(Suppl.2), (pp. S132). [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Fleming, S. B., Seet, B. T., Haig, D., McCaughan, C. A., Baird, M., Imlach, W., Lateef, Z., Wise, L. M., … Mercer, A. A. (2005, November). Immune evasion strategies of the Parapoxvirus Orf virus. Verbal presentation at the SBMB New Zealand and the NZMS Conference, Dunedin, New Zealand.
2004
Conference Contribution - Poster Presentation (not in published proceedings)
Inder, M. K., Wise, L. M., Fleming, S. B., & Mercer, A. A. (2004, November). The structure-function analysis of a viral-encoded vascular endothelial growth factor. Poster session presented at the 14th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand.
2003
Journal - Research Article
Wise, L., Ueda, N., Dryden, N. H., Fleming, S. B., Caesar, C., Roufail, S., … Mercer, A. A. (2003). Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor-binding specificities, and the ability to induce vascular permeability yet are uniformly active mitogens. Journal of Biological Chemistry, 278(39), 38004-38014.
Ueda, N., Wise, L., Stacker, S. A., Fleming, S. B., & Mercer, A. A. (2003). Pseudocowpox virus encodes a homolog of vascular endothelial growth factor. Virology, 305, 298-309.
Conference Contribution - Verbal presentation and other Conference outputs
Mercer, A., Wise, L., Ueda, N., Fleming, S., Achen, M., & Stacker, S. (2003, December). Functional analysis of a unique viral vascular endothelial growth factor (VEGF). Verbal presentation at the 2nd Australian Virology Group Meeting, Fraser Island, Australia.
Intellectual Property
Wise, L. M., Mercer, A. A., Savory, L. J., Fleming, S. B., & Stacker, S. (2003). Vascular endothelial growth factor-like protein from orf viruses binds and activates mammalian VEGF receptor-2, and uses thereof. United States patent (US 6,541,008 B1).
2002
Journal - Research Article
Mercer, A. A., Wise, L. M., Scagliarini, A., McInnes, C. J., Buttner, M., Rziha, H. J., McCaughan, C. A., Fleming, S. B., Ueda, N., & Nettleton, P. F. (2002). Vascular endothelial growth factors encoded by orf virus show surprising sequence variation but have a conserved, functionally relevant structure. Journal of General Virology, 83, 2845-2855.
Conference Contribution - Published proceedings: Abstract
Wise, L. M., Ueda, N., Scagliarini, A., McInnes, C. J., Buettner, M., Rziha, H. J., … Fleming, S. B., … Mercer, A. A. (2002). Parapoxvirus-encoded vascular endothelial growth factors conserve structure and function despite extensive sequence variation. XIVth International Poxvirus and Iridovirus Symposium. (pp. 10). New York. [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Wise, L., Ueda, N., Scagliarini, A., McInnes, C. J., Buettner, M., Rhiza, H. J., … Fleming, S. B., … Mercer, A. A. (2002). Parapoxvirus-encoded vascular endothelial growth factors conserve structure and function despite extensive sequence variation. Verbal presentation at the XIVth International Poxvirus and Iridovirus Symposium, Lake Placid, USA.
Awarded Doctoral Degree
Wise, L. (2002). Characterisation of the vascular endothelial growth factor proteins encoded by parapoxviruses University of Otago, Dunedin.
2001
Journal - Research Article
Makinen, T., Veikkola, T., Mustjoki, S., Karpanen, T., Catimel, B., Nice, E., Wise, L. M., Mercer, A. A., … Alitalo, K. (2001). Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3. EMBO Journal, 20(17), 4762-4773.
Conference Contribution - Published proceedings: Abstract
Ueda, N., Wise, L. M., Stacker, S. A., Savory, L. J., Fleming, S. B., Caesar, C., … Mercer, A. A. (2001). A vascualr endothelial growth factor (VEGF) encoded by Pseudocowpox virus. American Society of Virology 20th Annual Meeting. [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Ueda, N., Wise, L. M., Stacker, S. A., Savory, L. J., Fleming, S. B., Caesar, C., … Mercer, A. A. (2001, July). A vascular endothelial growth factor (VEGF) encoded by Pseudocowpox virus. Poster session presented at the American Society of Virology 20th Annual Meeting, Madison, USA.
2000
Journal - Research Article
Fleming, S. B., Haig, D. M., Nettleton, P., Reid, H. W., McCaughan, C. A., Wise, L. M., & Mercer, A. (2000). Sequence and functional analysis of a homolog of interleukin-10 encoded by the parapoxvirus orf virus. Virus Genes, 21(1-2), 85-95.
Fleming, S. B., Haig, D. M., Nettleton, P. F., Reid, H. W., McCaughlan, C. A., Wise, L. M., & Mercer, A. A. (2000). Sequence and functional analysis of a homolog of interleukin-10 encoded by the parapoxvirus, orf virus. Virus Genes, 21(1/2), 85-90.
Conference Contribution - Published proceedings: Abstract
Savory, L. J., Stacker, S. A., Fleming, S. B., Lyttle, D. J., Wise, L. M., & Mercer, A. A. (2000). Functional analysis of two orf-virus encoded variants of vascular endothelial growth factor. Proceedings of XIII Poxvirus Meeting. [Abstract]
Ueda, N., Wise, L. M., Stacker, S. A., Savory, L. J., Fleming, S. B., Caesar, C., … Mercer, A. A. (2000). Pseudocowpox virus encodes a homolog of the orf virus vascular endothelial growth factor. XIIIth International Poxvirus and Iridovirus Symposium. (pp. 113). France. [Abstract]
Wise, L. M., Mercer, A. A., Savory, L. J., Fleming, S. B., Caesar, C., Vitali, A., & Stacker, S. A. (2000). Orf virus-encoded vascular endothelial growth factor: a family of varient growth factors. XIII Poxvirus Meeting. (pp. 177). [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Ueda, N., Wise, L. M., Stacker, S. A., Savory, L. J., Fleming, S. B., Caesar, C., … Mercer, A. A. (2000, September). Pseudocowpox virus encodes a homolog of the orf virus vascular endothelial growth factor-like proteins. Poster session presented at the XIIIth International Poxvirus and Iridovirus Symposium, Montpellier, France.
Conference Contribution - Verbal presentation and other Conference outputs
Wise, L. M., Mercer, A. A., Savory, L. J., Fleming, S. B., Caesar, C., Vitali, A., & Stacker, S. A. (2000, September). Orf virus encoded VEGF: A family of variant growth factors? Verbal presentation at the XIII International Poxvirus and Iridovirus Symposium, Montpellier.
Savory, L. J., Stacker, S. A., Fleming, S. B., Lyttle, D. J., Wise, L. M., & Mercer, A. A. (2000, September). Functional analysis of two orf virus-encoded variants of vascular endothelial growth factor (VEGF). Verbal presentation at the XIII International Poxvirus and Iridovirus Symposium, Montpellier.
1999
Journal - Research Article
Wise, L. M., Veikkola, T., Mercer, A. A., Savory, L. J., Fleming, S. B., Caesar, C., … Stacker, S. A. (1999). Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1. PNAS, 96(6), 3071-3076. doi: 10.1073/pnas.96.6.3071
Conference Contribution - Published proceedings: Abstract
Stacker, S. A., Wise, L. M., Mercer, A. A., Stenvers, K., Caesar, C., Vitali, A., … Savory, L. J., Fleming, S. B., … Achen, M. G. (1999). Vascular endothelial growth factor (VEGF) family: their role in blood vessel growth, lymphatic development and viral infection. Queenstown Molecular Biology Meeting. (pp. 36). [Abstract]
Wise, L. M., Savory, L. J., Veikkola, T., Fleming, S. B., Caesar, C., Vitali, A., Whelan, E., … Mercer, A. A. (1999). Orf virus encodes a bioactive vascular endothelial growth factor (VEGF). Queenstown Molecular Biology Meeting. (pp. 13). [Abstract]
Wise, L. M., Veikkola, T., Mercer, A. A., Savory, L. J., Fleming, S. B., Caesar, C., … Stacker, S. A. (1999). The vascualr endothelial growth factor (VEGF)-like protein from orf virus binds and activates VEGF receptors. XIth International Congress of Virology. (pp. 152). [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Wise, L. M., Veikkola, T., Mercer, A. A., Savory, L. J., Fleming, S. B., Caesar, C., … Stacker, S. (1999, August). The vascular endothelial growth factor (VEGF)-like protein from orf virus binds and activates VEGF receptors. Verbal presentation at the XI International Congress of Virology, Sydney, Australia.
Intellectual Property
Wise, L., Mercer, A. A., Savory, L. J., Fleming, S. B., & Stacker, S. (1999). Vascular endothelial growth factor-like protein from orf virus NZ2 binds and activates VEGF receptor-2 and uses thereof. United States patent (09/431,888).
Wise, L. M., Mercer, A. A., Savory, L. J., Fleming, S. B., & Stacker, S. (1999). Vascular endothelial growth factor -like protein from orf virus NZ2 binds and activates VEGF receptor-2 and uses thereof.. US Application 09/431,888 filed November 1999. U.S. Patent and Trademark Office.