
Contact Details
- Phone
- +64 3 479 4300
- dvc.pacific@otago.ac.nz
University Links
- Position
- Professor (Immunology), Deputy Vice-Chancellor, Pacific
- Department
- Pacific Development Office
- Qualifications
- Cert AT(AIT) DPH(Otago) BSc BBMedSc PGCertEdPD PGDipHELT MBMEDSC(Hons) PhD(VUW)
- Research summary
- Immunology, Cancer, Acute Rheumatic Fever, Rheumatic Heart Disease, COVID-19, Pacific health
Research
Dianne Sika-Paotonu is a Professor of Immunology and Deputy Vice-Chancellor, Pacific, at the University of Otago. She is a Fulbright Scholar, having returned from the United States after working as an Immunology Scientist at Harvard University based in the Harvard T.H. Chan School of Public Health, and in the Health Sciences Centre at the University of Oklahoma.
Dianne is an experienced research scientist, educator and science communicator and commentator, teaching, supervising, and mentoring students and holding leadership roles within the tertiary sector for many years. Her areas of research focus include rheumatic fever and rheumatic heart disease, cancer and early diagnosis, health equity and inequities, and infectious diseases, and she has established research collaborations leading as Principal Investigator across multiple projects nationally and internationally working with collaborators in overseas and into the Pacific region and beyond. Dianne’s leadership and scientific contributions to these interdisciplinary research projects are evidence based, equity focused, and inclusivity driven, utilising her Pacific health, scientific and immunological expertise.
Science communication and advocacy
Dianne regularly presents at scientific conferences, and over the years has received national and international awards relating to her research work and science communication efforts. She holds numerous service and leadership responsibilities and contributes to local, national and international groups, committees and boards, functioning as chair and/or convenor for many of these.
Dianne has a long-standing track record of advocacy and engagement efforts with many groups, while seeking to address health inequities in society more generally, as the basis for the scientific work she leads and supports.
PhD Research
Dianne completed her PhD in Biomedical Science specialising in Immunology at the Malaghan Institute of Medical Research as a member of the cancer vaccines team undertaking work that explored modification of these vaccines to generate stronger immune responses against cancer. Her work showed that increased numbers of cancer-killing immune cells could be generated when synthetic compounds that mimic infected tissue were incorporated into the cancer vaccine preparation. Her work also highlighted the role of specific sub-populations of immune cells in generating these cancer-killing immune responses.
Dianne’s work overall aimed to improve of the potency of these cancer vaccines for the treatment of all cancers. Dianne also previously worked at the Telethon Kids Institute in Perth Western Australia as the Scientific Lead for the Penicillin Research programme within the Group A Streptococcal Disease team based at the Wesfarmers Centre for Vaccines and Infectious Diseases.
Awards
Dianne is an award-winning scientist, Fulbright Scholar, receiving national and international awards for her research work including the Prime Minister's Science Communication Prize, Callaghan Medal 2024, AAW Woman of the Year Award, USA, Liley Medal-Team Award, Cranwell Medal, MacDiarmid New Zealand Young Scientist of the Year – Advancing Human Health & Wellbeing, Colmar Brunton Research Excellence Award, Australasian Society of Immunology BD Science Communication Award, Asia Pacific Science Technology Studies Networks New Contributions to Science Technology & Innovation Award-Indigenous studies, and the Australasian Society of Immunology Buck Memorial Award, among others.
Dianne was also recipient of the Royal Order Award the Most Illustrious Royal Order of Queen Salote Tupou III-Commander, awarded by the late King George Tupou V of Tonga in recognition of scientific achievement.
Academic qualifications
She’s completed a BSc (Physiology), BBMedSc (Molecular Pathology), MBMedSc (1st class Hons - Molecular Pathology), DPH (Public Health), PGDipHELT (Higher Education Learning and Teaching), PGCert (Education & Professional Development), Certificate (Anaesthetic Technology) and PhD (Immunology).
Publications
Lao, C., Gurney, J., Stanley, J., Teng, A., Kuper-Hommel, M., Campbell, I., Krebs, J., Sika-Paotonu, D., Koea, J., Stairmand, J., & Lawrenson, R. (2025). Differences in systemic treatments for breast cancer between patients with and without diabetes. New Zealand Medical Journal/Te ara tika o te hauora hapori, 138(1613), 67-78. Retrieved from https://www.nzmj.org.nz/ Journal - Research Article
Teng, A., Stanley, J., Krebs, J., Jackson, C. G. C. A., Koea, J., Scott, N., Sika-Paotonu, D., Stairmand, J., … Gurney, J. (2025). Projected increases in the prevalence of diabetes mellitus in Aotearoa New Zealand, 2020–2044. New Zealand Medical Journal/Te ara tika o te hauora hapori, 138(1608), 94-106. Retrieved from https://www.nzmj.org.nz/ Journal - Research Article
Teng, A., Stanley, J., Lawrenson, R., Lao, C., Krebs, J., Koea, J., Sika-Paotonu, D., & Gurney, J. (2025). Co-occurence of cancer and diabetes in a high-income country: Age-period-cohort projections 2020-2024. Cancer Epidemiology, 94, 102723. doi: 10.1016/j.canep.2024.102723 Journal - Research Article
Wirth, S., Sika-Paotonu, D., Beaton, A., Raghu, A., Steer, A., & Carapetis, J. (2024). Acute rheumatic fever and rheumatic heart disease. In J. J. Ferretti, D. L. Stevens & V. A. Fischetti (Eds.), Streptococcus pyogenes: Basic biology to clinical manifestations. (2nd ed.) (pp. 617-660). Oklahoma City, OK: University of Oklahoma Health Sciences Center. Chapter in Book - Research
Burgess, J., Raman, S., Wiles, S., Long, A.-M., Smith-Ali, D., Sesan, T., & Sika-Paotonu, D. (2024, June). Science communication as a human right. Panel discussion at the Australian Science Communicators (ASC) National Conference: Support connect grow, Perth, Australia. Conference Contribution - Verbal presentation and other Conference outputs
2025
Journal - Research Article
Lao, C., Gurney, J., Stanley, J., Teng, A., Kuper-Hommel, M., Campbell, I., Krebs, J., Sika-Paotonu, D., Koea, J., Stairmand, J., & Lawrenson, R. (2025). Differences in systemic treatments for breast cancer between patients with and without diabetes. New Zealand Medical Journal/Te ara tika o te hauora hapori, 138(1613), 67-78. Retrieved from https://www.nzmj.org.nz/
Teng, A., Stanley, J., Krebs, J., Jackson, C. G. C. A., Koea, J., Scott, N., Sika-Paotonu, D., Stairmand, J., … Gurney, J. (2025). Projected increases in the prevalence of diabetes mellitus in Aotearoa New Zealand, 2020–2044. New Zealand Medical Journal/Te ara tika o te hauora hapori, 138(1608), 94-106. Retrieved from https://www.nzmj.org.nz/
Teng, A., Stanley, J., Lawrenson, R., Lao, C., Krebs, J., Koea, J., Sika-Paotonu, D., & Gurney, J. (2025). Co-occurence of cancer and diabetes in a high-income country: Age-period-cohort projections 2020-2024. Cancer Epidemiology, 94, 102723. doi: 10.1016/j.canep.2024.102723
2024
Chapter in Book - Research
Wirth, S., Sika-Paotonu, D., Beaton, A., Raghu, A., Steer, A., & Carapetis, J. (2024). Acute rheumatic fever and rheumatic heart disease. In J. J. Ferretti, D. L. Stevens & V. A. Fischetti (Eds.), Streptococcus pyogenes: Basic biology to clinical manifestations. (2nd ed.) (pp. 617-660). Oklahoma City, OK: University of Oklahoma Health Sciences Center.
Journal - Research Article
Lawrenson, R., Lao, C., Stanley, J., Teng, A., Kuper-Hommel, M., Campbell, I., Krebs, J., Sika-Paotonu, D., … Gurney, J. (2024). Does diabetes affect breast cancer survival? Cancer Reports, e2040. doi: 10.1002/cnr2.2040
Oetzel, J., Ngawati, R., Penetito‑Hemara, D., Te Puke, T., Henry, A., Povaru‑Bourne, S., & Sika-Paotonu, D. (2024). Facilitators and barriers for implementation of health programmes with Māori communities. Implementation Science Communications, 5, 26. doi: 10.1186/s43058-024-00567-y
Teng, A., Stanley, J., Jackson, C., Koea, J., Lao, C., Lawrenson, R., … Sika-Paotonu, D., & Gurney, J. (2024). The growing cancer burden: Age-period-cohort projections in Aotearoa New Zealand 2020-2044. Cancer Epidemiology, 89, 102535. doi: 10.1016/j.canep.2024.102535
Lacey, J. A., Bennett, J., James, T. B., Hines, B. S., Chen, T., Lee, D., Sika-Paotonu, D., … Baker, M. G., … Moreland, N. J. (2024). A worldwide population of Streptococcus pyogenes strains circulating among school-aged children in Auckland, New Zealand: A genomic epidemiology analysis. Lancet Regional Health: Western Pacific, 24, 100964. doi: 10.1016/j.lanwpc.2023.100964
Journal - Research Other
Kvalsvig, A., Brooks, A. E. S., Potter, J. D., Jeffreys, M., Bennett, J., Davies-Payne, D., Kennedy, J., Sika-Paotonu, D., Timu-Parata, C., … Hume, C., … Lorgelly, P., & Baker, M. (2024). Long Covid in Aotearoa NZ: Risk assessment and preventive action urgently needed. The Briefing, (26 March). Retrieved from https://www.phcc.org.nz/briefing/long-covid-aotearoa-nz-risk-assessment-and-preventive-action-urgently-needed
Conference Contribution - Published proceedings: Abstract
Lawrenson, R., Lao, C., Stanley, J., Kuper-Hommel, M., Campbell, I., Krebs, J., Sika-Paotonu, D., … Stairmand, J., & Gurney, J. (2024). Does diabetes affect systematic treatments for breast cancer? Proceedings of the 47th New Zealand Society for the Study of Diabetes (NZSSD) Annual Scientific Meeting. P1. Retrieved from https://www.nzssd.org.nz/
Conference Contribution - Verbal presentation and other Conference outputs
Burgess, J., Raman, S., Wiles, S., Long, A.-M., Smith-Ali, D., Sesan, T., & Sika-Paotonu, D. (2024, June). Science communication as a human right. Panel discussion at the Australian Science Communicators (ASC) National Conference: Support connect grow, Perth, Australia.
Sika-Paotonu, D. (2024, June). The potential, power and perils of science communication. Keynote presentation at the Australian Science Communicators (ASC) National Conference: Support connect grow, Perth, Australia.
Smith-Ali, D., Long, A.-M., Sesan, T., Sika-Paotonu, D., Wiles, S., & Raman, S. (2024, June). Keynote panel. Panel discussion at the Science Communication as a Human Right Conference, [Hybrid].
2023
Journal - Research Article
Cleverley, T., Meredith, I., Sika-Paotonu, D., & Gurney, J. (2023). Cancer incidence, mortality and survival for Pacific Peoples in Aotearoa New Zealand. New Zealand Medical Journal/Te ara tika o te hauora hapori, 136(1586), 12-31. Retrieved from https://journal.nzma.org.nz/
Gurney, J., Stanley, J., Teng, A., Robson, B., Scott, N., Sika-Paotonu, D., … Krebs, J., & Koea, J. (2023). Equity of cancer and diabetes co-occurrence: A national study with 44 million person-years of follow-up. JCO Global Oncology, 9, e2200357. doi: 10.1200/GO.22.00357
Lawrenson, R., Lao, C., Stanley, J., Campbell, I., Krebs, J., Meredith, I., Koea, J., Teng, A., Sika-Paotonu, D., Stairmand, J., & Gurney, J. (2023). Impact of diabetes on surgery and radiotherapy for breast cancer. Breast Cancer Research & Treatment, 199, 305-314. doi: 10.1007/s10549-023-06915-1
Bako, K. R., Reynolds, A. N., Sika-Paotonu, D., Signal, L., & Mohammadnezhad, M. (2023). Identifying factors which enhance the self-management of type 2 diabetes: A systematic review with thematic analysis. Global Journal of Health Science, 15(1), 1-19. doi: 10.5539/gjhs.v15n1p1
Lao, C., Gurney, J., Stanley, J., Krebs, J., Meredith, I., Campbell, I., Teng, A., Sika-Paotonu, D., Koea, J., & Lawrenson, R. (2023). Association of diabetes and breast cancer characteristics at diagnosis. Cancer Causes & Control, 34, 103-111. doi: 10.1007/s10552-022-01654-y
Journal - Research Other
Bako, K. R., Mohammadnezhad, M., Sika-Paotonu, D., Sime, S., & Signal, L. (2023). Diabetes Cam: An objective methodology to study diabetes self-management. American Journal of Preventive Medicine. Advance online publication. doi: 10.1016/j.amepre.2023.12.016
Conference Contribution - Published proceedings: Abstract
Sika-Paotonu, D., Taramai, A., Teumohenga, R., & Tagi, S. (2023). The appropriate application and utilisation of a Pacific model of health and well being for immunology based health sciences education. Journal of Immunology, 210(Suppl. 1), 232.04. doi: 10.4049/jimmunol.210.Supp.75.01
Sika-Paotonu, D. (2023). Viral immunology in the context of COVID-19. Journal of Immunology, 210(Suppl. 1), 75.01. doi: 10.4049/jimmunol.210.Supp.75.01
Sika-Paotonu, D. (2023). Enhancing immunology based health sciences education for addressing health inequities: in the context of COVID-19. Journal of Immunology, 210(Suppl. 1), 232.03. doi: 10.4049/jimmunol.210.Supp.74.01
Sika-Paotonu, D. (2023). Vaccine immunology in the context of COVID-19. Journal of Immunology, 210(Suppl. 1), 74.01. doi: 10.4049/jimmunol.210.Supp.74.01
Conference Contribution - Verbal presentation and other Conference outputs
Sika-Paotonu, D. (2023, November). Science communication. Keynote presentation at the Science Communicators Association of New Zealand (SCANZ) Conference: Techtopia: Navigating the Power, Potential and Perils of Technology in Science Communication, Wellington, New Zealand.
2022
Journal - Research Article
Gurney, J., Stanley, J., Teng, A., Krebs, J., Koea, J., . . ., Sika-Paotonu, D., & Sarfati, D. (2022). Cancer and diabetes co-occurrence: A national study with 44 million person-years of follow-up. PLoS ONE, 17(11), e0276913. doi: 10.1371/journal.pone.0276913
Bennett, J., Moreland, N. J., Zhang, J., Crane, J., Sika-Paotonu, D., Carapetis, J., Williamson, D. A., & Baker, M. G. (2022). Risk factors for group A streptococcal pharyngitis and skin infections: A case control study. Lancet Regional Health: Western Pacific, 26, 100507. doi: 10.1016/j.lanwpc.2022.100507
Journal - Research Other
Oetzel, J., Sika-Paotonu, D., Penetito-Hemara, D., & Henry, A. (2022). Healthier Lives Implementation Research Network for Māori and Pacific community health providers in Aotearoa New Zealand: A study protocol with an observational mixed methods design. Implementation Science Communications, 3, 122. doi: 10.1186/s43058-022-00373-4
Conference Contribution - Verbal presentation and other Conference outputs
Dew, K., Hendy, S., Russell, J., & Sika-Paotonu, D. (2022, December). The sticky arts of science communication in crisis times. Plenary presentation at the Sociological Association of Aotearoa New Zealand (SAANZ) Conference: Now what? Reimagining hope, 'truth' and equality, Auckland, New Zealand.
2021
Journal - Research Article
Oliver, J., Robertson, O., Zhang, J., Marsters, B. L., Sika-Paotonu, D., Jack, S., Bennett, J., Williamson, D. A., … Pierse, N., & Baker, M. G. (2021). Early release-ethnically disparate disease progression and outcomes among acute rheumatic fever patients in New Zealand, 1989–2015. Emerging Infectious Diseases, 27(7), 1893-1901. doi: 10.3201/eid2707.203045
Bennett, J., Zhang, J., Leung, W., Jack, S., Oliver, J., Webb, R., … Sika-Paotonu, D., Harwood, M., & Baker, M. G. (2021). Rising ethnic inequalities in acute rheumatic fever and rheumatic heart disease, New Zealand, 2000-2018. Emerging Infectious Diseases, 27(1), 36-46. doi: 10.3201/eid2701.191791
Journal - Research Other
Bennett, J., Anderson, A., 'Ofanoa, M., Anderson, P., Baker, M. G., Brown, R., … Eggleton, K., Harwood, M., … Malcolm, J., … Sika-Paotonu, D., … Wilson, N. (2021). Acute rheumatic fever: A preventable, inequitable disease: A call for action. New Zealand Medical Journal, 134(1535), 93-95. Retrieved from https://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Sika-Paotonu, D. (2021). The integration of immunology based pharmacological elements for health sciences education. Journal of Immunology, 206(Suppl. 1), 54.24. [Abstract]
Sika-Paotonu, D., Patel, J., Reed, K., McTavish, A., Humphries, F., & Motu, L. (2021). Immunology education within an undergraduate program for health sciences education. Journal of Immunology, 206(Suppl. 1), 54.23. [Abstract]
Sika-Paotonu, D., Walton, M., Faavae, S., Tagi, S., & Guilford, P. (2021). Diagnostic approaches for early cancer detection in Pacific youth using ctDNA technology. Journal of Immunology, 206(Suppl. 1), 26.21. [Abstract]
Sika-Paotonu, D. (2021). Active learning strategies incorporating Immunology based teaching examples for health sciences education. Journal of Immunology, 206(Suppl. 1), 54.22. [Abstract]
Sika-Paotonu, D., Walton, M., Finau, E., Faavae, S., Vaimoli, J., & Guilford, P. (2021). The clinical considerations for early cancer detection using ctDNA within the Pacific setting. Journal of Immunology, 206(Suppl. 1), 12.08. [Abstract]
Sika-Paotonu, D. (2021). A Novel approach towards drug design. Journal of Immunology, 206(Suppl. 1), 95.16. [Abstract]
Sika-Paotonu, D. (2021). Designing vaccines to combat cancer: An indigenous approach. Journal of Immunology, 206(Suppl. 1), 58.12. [Abstract]
Sika-Paotonu, D. (2021). Using an indigenous framework to contextualise immunology education within the health sciences setting. Journal of Immunology, 206(Suppl. 1), 54.26. [Abstract]
Sika-Paotonu, D. (2021). Therapeutic cancer vaccines in the Pacific region. Journal of Immunology, 206(Suppl. 1), 58.11. [Abstract]
Working Paper; Discussion Paper; Technical Report
Harwood, M., Anderson, A., Murdoch, D., Sika-Paotonu, D., Heinemann, J., Dyet, K., … Wiles, S. (2021). Executive summary: Group A Streptococcus and acute rheumatic fever in Aotearoa New Zealand: A summary of current knowledge in Aotearoa New Zealand. (pp. 1-7). Auckland, New Zealand: Office of the Prime Minister’s Chief Science Advisor, Kaitohutohu Mātanga Pūtaiao Matua ki te Pirimia. Retrieved from https://cpb-ap-se2.wpmucdn.com/blogs.auckland.ac.nz/dist/f/688/files/2021/12/OPMCSA-rheumatic-fever-evidence-synthesis-Exec-summary-to-upload-v2.pdf
Harwood, M., Anderson, A., Murdoch, D., Sika-Paotonu, D., Heinemann, J., Dyet, K., … Wiles, S. (2021). Evidence synthesis: Group A Streptococcus and acute rheumatic fever in Aotearoa New Zealand: A summary of current knowledge in Aotearoa New Zealand. (pp. 1-107). Auckland, New Zealand: Office of the Prime Minister’s Chief Science Advisor, Kaitohutohu Mātanga Pūtaiao Matua ki te Pirimia. Retrieved from https://cpb-ap-se2.wpmucdn.com/blogs.auckland.ac.nz/dist/f/688/files/2021/12/OPMCSA-rheumatic-fever-to-upload-on-Nov-19-v2.pdf
Gerrard, J., Harwood, M., Anderson, A., Murdoch, D., Sika-Paotonu, D., Heinemann, J., … Wiles, S. (2021). Kotahitanga: Uniting Aotearoa against infectious disease and antimicrobial resistance: Key messages. (pp. 1-37). Auckland, New Zealand: Office of the Prime Minister’s Chief Science Advisor, Kaitohutohu Mātanga Pūtaiao Matua ki te Pirimia. Retrieved from https://cpb-ap-se2.wpmucdn.com/blogs.auckland.ac.nz/dist/f/688/files/2020/01/Short-report-web-v4.pdf
Gerrard, J., Harwood, M., Anderson, A., Murdoch, D., Sika-Paotonu, D., Heinemann, J., … Wiles, S. (2021). Kotahitanga: Uniting Aotearoa against infectious disease and antimicrobial resistance. (pp. 1-405). Auckland, New Zealand: Office of the Prime Minister’s Chief Science Advisor, Kaitohutohu Mātanga Pūtaiao Matua ki te Pirimia. [Technical/Scientific Report].
2020
Journal - Research Article
Hand, R. M., Senarathna, S. M. D. K. G., Page-Sharp, M., Gray, K., Sika-Paotonu, D., Sheel, M., … Batty, K. T. (2020). Quality of benzathine penicillin G: A multinational cross-sectional study. Pharmacology Research & Perspectives, 8(6), e. doi: 10.1002/prp2.668
Filoche, S., Stone, P., Cram, F., Bacharach, S., Dowell, A., Sika-Paotonu, D., … Ormandy, J., … Thunders, M., & Dew, K. (2020). Uncovering social structures and informational prejudices to reduce inequity in delivery and uptake of new molecular technologies. Journal of Medical Ethics, 46, 763-767. doi: 10.1136/medethics-2019-105734
Journal - Research Other
Signal, V., Gurney, J., Inns, S., McLeod, M., Sika-Paotonu, D., Sowerbutts, S., Teng, A., & Sarfati, D. (2020). Helicobacter pylori, stomach cancer and its prevention in New Zealand. Journal of the Royal Society of New Zealand, 50(3), 397-417. doi: 10.1080/03036758.2019.1650081
Conference Contribution - Published proceedings: Abstract
Sika-Paotonu, D. (2020). Cancer vaccines in the Pacific region. Journal of Immunology, 204(1, Suppl.), 169.34. [Abstract]
Sika-Paotonu, D. (2020). Connecting with STEM and immunology in the classroom: The importance of role modelling. Journal of Immunology, 204(1, Suppl.), 222.34. [Abstract]
Sika-Paotonu, D. (2020). Contextualisation of immunology related STEM examples to support youth interest and engagement. Journal of Immunology, 204(1, Suppl.), 222.29. [Abstract]
Sika-Paotonu, D. (2020). Immunology based STEM outreach education efforts that support knowledge translation for Pacific college students. Journal of Immunology, 204(1, Suppl.), 222.33. [Abstract]
Sika-Paotonu, D., & Cockburn, A. (2020). The importance of cultural context in supporting STEM related immunology content for high school students. Journal of Immunology, 204(1, Suppl.), 222.30. [Abstract]
Sika-Paotonu, D., Chandra, P., De Silva, H., Hermann, Z., Lowry, F., Papalii, S., Rajakumaran, P., Simpson, E., Walton, M., & Mitchell, M. (2020). Appropriate contextualisation of immunology based STEM and health teaching for undergraduate Medical Sciences Education. Journal of Immunology, 204(1, Suppl.), 222.32. [Abstract]
Sika-Paotonu, D., Baltazar, P., Dudley, J., Gilespie, A., Logan, M., Su, T., Tam, V., & Walton, M. (2020). The utility and appropriate contextualisation of immunology based cancer related teaching examples with Medical Sciences Education. Journal of Immunology, 204(1, Suppl.), 222.31. [Abstract]
Sika-Paotonu, D., Anderson, J., Cashin, P., & Cockburn, A. (2020). Immunology that supports STEM participation for high school students. Journal of Immunology, 204(1, Suppl.), 222.28. [Abstract]
Sika-Paotonu, D., Anitelea, T., Cockburn, A., & Guilford, P. (2020). Early cancer detection using ctDNA technology: What is the relevance for Pacific communities? Journal of Immunology, 204(1, Suppl.), 159.54. [Abstract]
Sika-Paotonu, D., Anitelea, T., Faatoese, A., Laing, B., Puni, R., Vaipuna, T., & Guilford, P. (2020). ctDNA for early cancer diagnosis in Pacific communities. Journal of Immunology, 204(1, Suppl.), 86.51. [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Sika-Paotonu, D. (2020, December). Drug design and addressing health Inequalities: Towards a new penicillin for ARF and RHD prevention. Invited presentation at the 8th One Health Aotearoa (OHA) Symposium, [Hybrid].
Other Research Output
Sika-Paotonu, D. (2020, June). RE: Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells. Science eLetters. Retrieved from https://science.sciencemag.org/content/368/6494/eaaz7548/tab-e-letters
Sika-Paotonu, D. (2020, June). RE: Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition. Science eLetters. Retrieved from https://stm.sciencemag.org/content/11/494/eaau6246/tab-e-letters
Sika-Paotonu, D. (2020, June). RE: Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease. Science eLetters. Retrieved from https://stm.sciencemag.org/content/11/494/eaau9087/tab-e-letters
Sika-Paotonu, D. (2020, June). Reducing transmission of SARS-CoV-2: The clinical relevance and practical application of scientific research studies during a global Pandemic. Science eLetters. Retrieved from https://science.sciencemag.org/content/368/6498/1422/tab-e-letters
Sika-Paotonu, D. (2020, June). Responding to COVID-19: Testing tactics in the context of a global pandemic. Science eLetters. Retrieved from https://science.sciencemag.org/content/367/6484/1287/tab-e-letters
Sika-Paotonu, D. (2020, June). Moving academic research forward during the COVID-19 crisis: Considerations for researchers, academic institutions and colleges. Science eLetters. Retrieved from https://science.sciencemag.org/content/368/6496/1190/tab-e-letters
Sika-Paotonu, D. (2020, June). RE: Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies. Science eLetters. Retrieved from https://stm.sciencemag.org/content/12/530/eaax0876/tab-e-letters
Sika-Paotonu, D. (2020, June). RE: A biologic scaffold–associated type 2 immune microenvironment inhibits tumor formation and synergizes with checkpoint immunotherapy. Science eLetters. Retrieved from https://stm.sciencemag.org/content/11/477/eaat7973/tab-e-letters
Sika-Paotonu, D. (2020, June). RE: Peripheral lymph nodes contain migratory and resident innate lymphoid cell populations. Science eLetters. Retrieved from https://immunology.sciencemag.org/content/4/35/eaau8082/tab-e-letters
Sika-Paotonu, D. (2020, June). RE: CTLA-4 mediated transendocytosis of co-stimulatory molecules primarily targets migratory dendritic cells. Science eLetters. Retrieved from https://immunology.sciencemag.org/content/4/35/eaaw0902/tab-e-letters
Sika-Paotonu, D. (2020, May). Re: Pulmonary surfactant: Biomimetic nanoparticles potentiate heterosubtypic influenza immunity: Strengthening Influenza vaccination. Science eLetters. Retrieved from https://science.sciencemag.org/content/367/6480/eaau0810/tab-e-letters
Sika-Paotonu, D. (2020, May). Strengthening influenza vaccination: A vaccine adjuvant elicits broad protection against influenza in animals. Science eLetters. Retrieved from https://science.sciencemag.org/content/367/6480/852/tab-e-letters
Sika-Paotonu, D. (2020, May). RE: The deadly threat of COVID-19. Science eLetters. Retrieved from https://science.sciencemag.org/content/367/6485/1436.1/tab-e-letters
Sika-Paotonu, D. (2020, May). The impact of the COVID-19 Pandemic and the suspension of mass vaccination campaigns. Science eLetters. Retrieved from https://science.sciencemag.org/content/368/6487/116/tab-e-letters
Sika-Paotonu, D. (2020, May). RE: Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia. Science Translational Medicine eLetters. Retrieved from https://stm.sciencemag.org/content/11/515/eaax5866/tab-e-letters
Sika-Paotonu, D. (2020, March). Preventing COVID-19 prejudice in academia. Science eLetters. Retrieved from https://science.sciencemag.org/content/367/6484/1313.1
Sika-Paotonu, D. (2020, January). RE: Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis. Science eLetters. Retrieved from https://stm.sciencemag.org/content/9/378/eaah4680/tab-e-letters
2019
Journal - Research Article
Hand, R. M., Salman, S., Newall, N., Vine, J., Page-Sharp, M., Bowen, A. C., … Sika-Paotonu, D., … Carapetis, J. (2019). A population pharmacokinetic study of benzathine benzylpenicillin G administration in children and adolescents with rheumatic heart disease: New insights for improved secondary prophylaxis strategies. Journal of Antimicrobial Chemotherapy, 74, 1984-1991. doi: 10.1093/jac/dkz076
Journal - Research Other
Bennett, J., Moreland, N. J., Oliver, J., Crane, J., Williamson, D. A., Sika-Paotonu, D., … Baker, M. G. (2019). Understanding group A streptococcal pharyngitis and skin infections as causes of rheumatic fever: Protocol for a prospective disease incidence study. BMC Infectious Diseases, 19, 633. doi: 10.1186/s12879-019-4126-9
Conference Contribution - Published proceedings: Abstract
Sika-Paotonu, D., & Liligeto, U. (2019). The utility of Benzathine Penicillin G for rheumatic fever prevention in the Solomon Islands. Journal of Immunology, 202(1, Suppl.), 229.1. [Abstract]
Sika-Paotonu, D., & Liligeto, U. (2019). Group A Streptococcal infection, acute rheumatic fever and rheumatic heart disease in the Solomin Islands. Journal of Immunology, 202(1, Suppl.), 182.80. [Abstract]
Sika-Paotonu, D., Liligeto, U., & Guilford, P. (2019). Early cancer detection in the Pacific. Journal of Immunology, 202(1, Suppl.), 229.2. [Abstract]
Sika-Paotonu, D., & Guilford, P. (2019). Cancer in Pacific populations in New Zealand and ctDNA technology for early cancer detection. Journal of Immunology, 202(1, Suppl.), 229.3. [Abstract]
Sika-Paotonu, D., Yang, A., Vaipuna, K., Buckley, E., Bartlett, H., Kalyanasundaram, S., & Faatoese, A. (2019). Contextualisation of immunology based teaching for undergraduate medical science students that supports knowledge application. Journal of Immunology, 202(1, Suppl.), 61.20. [Abstract]
Sika-Paotonu, D., Gu, V., Williams, G., Pinfold, E., Whyte, J., Motu, L., Anitelea, T., Yuhoi, J., & Laing, B. (2019). The utilisation of clinically relevant immunological research examples for undergraduate medical sciences education. Journal of Immunology, 202(1, Suppl.), 61.19. [Abstract]
Sika-Paotonu, D. (2019). Role modelling immunology to support STEM education outreach efforts for Pacific college students. Journal of Immunology, 202(1, Suppl.), 61.17. [Abstract]
Sika-Paotonu, D. (2019). STEM knowledge translation outreach efforts: Connecting with immunology in the classroom for Pacific intermediate students. Journal of Immunology, 202(1, Suppl.), 61.18. [Abstract]
Sika-Paotonu, D., Anderson, J., Cashin, P., & Cockburn, A. (2019). An immunological basis for improving interest and participation of underrepresented student groups in high school science classes. Journal of Immunology, 202(1, Suppl.), 61.16. [Abstract]
Sika-Paotonu, D., & Cockburn, A. (2019). Immunology as a basis for STEM related teaching that is culturally appropriate and engages underrepresented high school students. Journal of Immunology, 202(1, Suppl.), 61.15. [Abstract]
Sika-Paotonu, D., Anitelea, T., Uiese, T., & Cockburn, A. (2019). Engaging with Pacific communities to support effective dialogue, appropriate outreach and scientific knowledge translation activity. Journal of Immunology, 202(1, Suppl.), 61.14. [Abstract]
Sika-Paotonu, D., Laing, B., Anitelea, T., Uiese, T., Puni, R., Vaipuna, T., & Fa'atoese, A. (2019). Supporting scientific knowledge communication and translation efforts by engaging appropriately with the Pacific audience. Journal of Immunology, 202(1, Suppl.), 61.11. [Abstract]
Oliver, J., Robertson, O., Zhang, J., Marsters, B., Sika-Paotonu, D., Williamson, D., … Pierse, N., & Baker, M. (2019). Progression of acute rheumatic fever to recurrence, rheumatic heart disease, and death in New Zealand children and youth: A cohort study. Heart, Lung & Circulation, 28(Suppl. 1), (pp. S4). doi: 10.1016/j.hlc.2019.05.013
Hand, R., Senarathna, S. M. D. K. G., Page-Sharp, M., Gray, K., Sika-Paotonu, D., Sheel, M., … Batty, K. T. (2019). Potency: Do we need a new manufacturing standard? Heart, Lung & Circulation, 28(Suppl. 2), (pp. S52-S53). doi: 10.1016/j.hlc.2019.05.135
Salman, S., Hand, R., Baker, A., Vine, J., Page-Sharp, M., Bowen, A., … Sika-Paotonu, D., … Carapetis, J. (2019). A population pharmacokinetic study of benzylpenicillin following benzathine benzylpenicillin administration in children and adolescents with rheumatic heart disease: New insights for improved secondary prophylaxis strategic. Internal Medicine Journal, 49(Suppl. 3), (pp. 6). doi: 10.1111/imj.3_14295
Conference Contribution - Poster Presentation (not in published proceedings)
Sika-Paotonu, D., Mitchell, M., Thornley, C., Betty, B., Wineera-Parai, R., Varday, B., … Tiatia, R., Baker, M., … Carapetis, J. (2019, April). The pharmacokinetics of Benzathine Penicillin G within indigenous population groups. Poster session presented at the 12th Health Disparities Conference, New Orleans, USA.
Sika-Paotonu, D., Yuhoi, J., Cockburn, A., Gu, V., Tiatia, R., Sung, Y. K., … Baker, M., … Carapetis, J. (2019, April). The Benzathine Penicillin G reformulation preferences of health professionals who deliver regular BPG injections for rheumatic fever prevention: An interim analysis. Poster session presented at the 12th Health Disparities Conference, New Orleans, USA.
Sika-Paotonu, D., Laing, B., Cockburn, A., Gu, V., Tiatia, R., Sung, Y. K., … Baker, M., … Carapetis, J. (2019, April). The Benzathine Penicillin G reformulation preferences of children and young people: An interim analysis. Poster session presented at the 12th Health Disparities Conference, New Orleans, USA.
Conference Contribution - Verbal presentation and other Conference outputs
Sika-Paotonu, D. (2019, February). Improving the formulation of Benzathine Penicillin G and its delivery. Verbal presentation at the Public Health Summer School Symposium: Update on Rheumatic Fever Prevention and Control, Wellington, New Zealand.
Sika-Paotonu, D., Motu, L., Cockburn, A., Gu, V., Tiatia, R., Sung, Y. K., … Baker, M., … Carapetis, J. (2019, April). The Benzathine Penicillin G reformulation preferences of families with a child or young person with rheumatic fever: An interim analysis. Verbal presentation at the 12th Health Disparities Conference, New Orleans, USA.
Other Research Output
Sika-Paotonu, D. (2019, March). RE: Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome. Science eLetters. Retrieved from https://stm.sciencemag.org/content/10/472/eaap8914/tab-e-letters
Sika-Paotonu, D. (2019, March). RE: Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay. Science eLetters. Retrieved from https://stm.sciencemag.org/content/11/473/eaau3174/tab-e-letters
Sika-Paotonu, D. (2019, February). RE: Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes. Science eLetters. Retrieved from https://science.sciencemag.org/content/359/6379/1037/tab-e-letters
Sika-Paotonu, D. (2019, March). RE: Regulatory T cells induce activation rather than suppression of human basophils. Science eLetters. Retrieved from https://immunology.sciencemag.org/content/3/23/eaan0829/tab-e-letters
Sika-Paotonu, D. (2019, March). Cell surface polysaccharides of Bifidobacterium bifidum induce the generation of Foxp3+ regulatory T cells. Science eLetters. Retrieved from https://immunology.sciencemag.org/content/3/28/eaat6975/tab-e-letters
Sika-Paotonu, D. (2019, March). Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue. Science eLetters. Retrieved from https://immunology.sciencemag.org/content/3/24/eaar4526/tab-e-letters
Sika-Paotonu, D. (2019, February). RE: Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1–infected individuals. Science eLetters. Retrieved from http://stm.sciencemag.org/content/10/461/eaau4711/tab-e-letters
Sika-Paotonu, D. (2019, February). RE: Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps. Science eLetters. Retrieved from http://immunology.sciencemag.org/content/3/26/eaar6676/tab-e-letters
Sika-Paotonu, D. (2019, February). RE: Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by Tenapanor reduces paracellular phosphate permeability. Science eLetters. Retrieved from http://stm.sciencemag.org/content/10/456/eaam6474/tab-e-letters
Sika-Paotonu, D. (2019, February). RE: MEK inhibition enhances oncolytic virus immunotherapy through increased tumor cell killing and T cell activation. Science eLetters. Retrieved from http://stm.sciencemag.org/content/10/471/eaau0417/tab-e-letters
Sika-Paotonu, D. (2019, February). RE: An increase in LRRK2 suppresses autophagy and enhances Dectin-1-induced immunity in a mouse model of colitis. Science eLetters. Retrieved from http://stm.sciencemag.org/content/10/444/eaan8162/tab-e-letters
Sika-Paotonu, D. (2019, February). RE: Generation and molecular recognition of melanoma-associated antigen-specific human γδ T cells. Science eLetters. Retrieved from http://immunology.sciencemag.org/content/3/30/eaav4036/tab-e-letters
Sika-Paotonu, D. (2019, February). RE: Type 3 cytokines IL-17A and IL-22 drive TGF-β–dependent liver fibrosis. Science eLetters. Retrieved from http://immunology.sciencemag.org/content/3/28/eaar7754/tab-e-letters
Sika-Paotonu, D. (2019, January). RE: Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis. Science eLetters. Retrieved from http://immunology.sciencemag.org/content/3/26/eaat2738/tab-e-letters
Sika-Paotonu, D. (2019, January). RE: Direct reprogramming of fibroblasts into antigen-presenting dendritic cells. Science eLetters. Retrieved from http://immunology.sciencemag.org/content/3/30/eaau4292/tab-e-letters
Sika-Paotonu, D. (2019, January). RE: HDAC inhibition improves autophagic and lysosomal function to prevent loss of subcutaneous fat in a mouse model of Cockayne syndrome. Science eLetters. Retrieved from http://stm.sciencemag.org/content/10/456/eaam7510/tab-e-letters
Sika-Paotonu, D. (2019, January). RE: p95HER2–T cell bispecific antibody for breast cancer treatment. Science eLetters. Retrieved from http://stm.sciencemag.org/content/10/461/eaat1445/tab-e-letters
2018
Chapter in Book - Research
Sika-Paotonu, D., Beaton, A., & Carapetis, J. (2018). Epidemiology and global burden of rheumatic heart disease. In A. J. Camm, T. F. Lüscher, G. Maurer & P. W. Serruys (Eds.), The ESC textbook of cardiovascular medicine. (3rd ed.) Oxford, UK: Oxford University Press. doi: 10.1093/med/9780198784906.003.0065
Journal - Research Other
Robertson, S. P., Harré Hindmarsh, J., Berry, S., Cameron, V. A., Cox, M. P., Dewes, O., … Matisoo-Smith, E., … Sika-Paotonu, D., … Merriman, T. R., … Wilcox, P. (2018). Genomic medicine must reduce, not compound, health inequities: The case for hauora-enhancing genomic resources for New Zealand. New Zealand Medical Journal, 131(1480), 81-89. Retrieved from https://www.nzma.org.nz/journal
Sarfati, D., Robson, B., Garvey, G., Goza, T., Foliaki, S., Millar, E., … on behalf of the participants of the Indigenous Peoples and Cancer Symposium, including Sika-Paotonu, D. (2018). Improving the health of Indigenous people globally. Lancet Oncology, 19(6), e276. doi: 10.1016/S1470-2045(18)30336-X
Conference Contribution - Published proceedings: Abstract
Salman, S., Hand, R., Newall, N., Baker, A., Vine, J., Page-Sharp, M., … Sika-Paotonu, D., … Carapetis, J. (2018). A population pharmacokinetic study of benzylpenicillin following benzathine benzylpenicillin administration in children and adolescents with rheumatic heart disease: New insights for improved secondary prophylaxis strategies. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Annual Scientific Meeting: Innovation in Therapeutics. 428. Retrieved from https://www.asceptasm.com/2018-annaul-scientific-meeting
Sika-Paotonu, D. (2018). The Benzathine Penicillin G (BPG) reformation studies: Towards a new penicillin for rheumatic fever and rheumatic heart disease [Plenary]. Proceedings of the Pacific International Health Symposium. (pp. 31). Retrieved from https://pihs.squarespace.com
Monerasinghe, R., Maude, R., & Sika-Paotonu, D. (2018). What is a 'normal' woman? The usefulness of labels such as 'normal' in the midwifery care of obese breastfeeding women. Proceedings of the New Zealand College of Midwives (NZCOM) 15th Biennial National Conference: One Voice: Women & Midwives: E nga Mareikura, Aro Tahi, Kokiri tahi. (pp. 10). Retrieved from https://legacy.midwife.org.nz/resources-events
Sika-Paotonu, D., Tiatia, R., Thornley, C., Betty, B., Wineera-Parai, R., Eddie, B., Baker, M., … Carapetis, J. (2018). Understanding protective plasma levels of penicillin and monitoring antibody responses for the prevention of GAS infection in a paediatric population in New Zealand. Journal of Immunology, 200(1, Suppl.), 45.46. [Abstract]
Hand, R. M., Bowen, A., Manning, L., Salman, S., Joseph, J., Sika-Paotonu, D., … Carapetis, J. (2018). Benzathine penicillin G pharmacokinetics in a predominately Australian Aboriginal adolescent population: A prospective observational study. Global Heart, 13(4), (pp. 519-520). doi: 10.1016/j.gheart.2018.09.503
Hand, R. M., Senarathna, G., Page-Sharp, M., Sika-Paotonu, D., Gray, K., Batty, K. T., & Carapetis, J. (2018). Benzathine penicillin G quality and potency: Do we need a new manufacturing standard? Global Heart, 13(4), (pp. 519). doi: 10.1016/j.gheart.2018.09.501
Sika-Paotonu, D., Tiatia, R., Sung, Y. K., Thornley, C., Betty, B., Wineera-Parai, R., … Baker, M., … Carapetis, J. (2018). The Benzathine Penicillin G (BPG) reformulation preferences study: The importance of cultural awareness and appropriate governance concerning Rheumatic Fever related research in New Zealand. Journal of Immunology, 200(1, Suppl.), 120.39. [Abstract]
Sika-Paotonu, D., Tiatia, R., Sung, Y. K., Thornley, C., Betty, B., Wineera-Parai, R., … Baker, M., … Carapetis, J. (2018). The Benzathine Penicillin G (BPG) reformulation preferences study-edging closer towards a new Penicillin for Rheumatic Fever and Rheumatic Heart Disease. Journal of Immunology, 200(1, Suppl.), 120.35. [Abstract]
Sika-Paotonu, D., Viali, S., Naseri, L. T. T. K., So'o, F. L. T. I. A., Lameko, T. V., Punivalu, M., … Tiatia, R., … Norris, P., … Baker, M., & Carapetis, J. (2018). The Benzathine Penicillin G (BPG) Reformulation Preferences Study: Samoa. Journal of Immunology, 200(1, Suppl.), 45.45. [Abstract]
Sika-Paotonu, D., Aho, G., 'Ulufonua, L. K., 'Ofanoa, M., Vaea, K., Tuipulotu, A. A., … Tiatia, R., … Norris, P., … Baker, M., & Carapetis, J. (2018). The Benzathine Penicillin G (BPG) Reformulation Preferences Study: Tonga. Journal of Immunology, 200(1, Suppl.), 166.68. [Abstract]
Sika-Paotonu, D., Vaea, K., 'Ulufonua, L. K., Akau'ola, S., Aho, G., Tuipulotu, A. A., … Guilford, P. (2018). The utilization of ctDNA technology as an early diagnostic tool for Cancer detection in Tonga. Journal of Immunology, 200(1, Suppl.), 120.38. [Abstract]
Sika-Paotonu, D., Viali, S., Naseri, L. T. T. K., So'o, F. L. T. I. A., Lameko, T. V., Punivalu, M., … Guilford, P. (2018). The application of ctDNA technology for early Cancer diagnostics in Samoa. Journal of Immunology, 200(1, Suppl.), 120.40. [Abstract]
Sika-Paotonu, D., & Guilford, P. (2018). The potential application of ctDNA technology as a cancer diagnostic tool within the Socialist Republic of Vietnam. Journal of Immunology, 200(1, Suppl.), 120.21. [Abstract]
Sika-Paotonu, D., & Guilford, P. (2018). Exploring the applicability of ctDNA technology as a diagnostic tool for improved Cancer care and management within the Pacific. Journal of Immunology, 200(1, Suppl.), 120.20. [Abstract]
Sika-Paotonu, D. (2018). The incorporation of active learner centered strategies to support improved memory recall and classroom engagement within postgraduate education blended learning education frameworks. Journal of Immunology, 200(1, Suppl.), 113.15. [Abstract]
Sika-Paotonu, D. (2018). The successful use of Immunology based Peer Teaching strategies within postgraduate clinical health sciences blended learning education frameworks. Journal of Immunology, 200(1, Suppl.), 113.14. [Abstract]
Sika-Paotonu, D. (2018). Translating knowledge and raising awareness of Immunology related human disease mechanisms via engagement with the general public and lay audience. Journal of Immunology, 200(1, Suppl.), 113.13. [Abstract]
Sika-Paotonu, D. (2018). The utilization of a clinically relevant Immunological research case example within undergraduate biomedical sciences education. Journal of Immunology, 200(1, Suppl.), 113.12. [Abstract]
Sika-Paotonu, D. (2018). Enhancing student knowledge and understanding of Immunology using integration of a clinically relevant Immunological condition within postgraduate clinical sciences education. Journal of Immunology, 200(1, Suppl.), 113.11. [Abstract]
Sika-Paotonu, D., & Tait, C. (2018). The utilization of scientific language communication techniques to enhance Immunology Education for Postgraduate Clinical Health Science students. Journal of Immunology, 200(1, Suppl.), 113.10. [Abstract]
Sika-Paotonu, D., & Laban, L. W. (2018). Knowledge translation for Cancer Immunotherapy and Immunology that is culturally appropriate and relevant within a Pacific context. Journal of Immunology, 200(1, Suppl.), 113.9. [Abstract]
Sika-Paotonu, D., & Tait, C. (2018). Immunology Education for English Second Language learners within a Postgraduate Nursing Science program in New Zealand. Journal of Immunology, 200(1, Suppl.), 113.18. [Abstract]
Sika-Paotonu, D., & Tait, C. (2018). The incorporation of Self-Directed Learning for English Second Language learners within postgraduate Clinical Health Sciences Immunology education. Journal of Immunology, 200(1, Suppl.), 113.6. [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Sika-Paotonu, D. (2018, February). Pacific populations, pharmacokinetics and immunology. Invited presentation at the Public Health Summer School Presentations: Emerging Issues for Te-Moana-Nui-A-Kiwa, Wellington, New Zealand.
Sika-Paotonu, D. (2018, November). A re-imagined workforce: Participate, innovate & reinvigorate: An update from the university of Otago Wellington. Panel discussion at the Pasifika Medical Association Conference, Auckland, New Zealand.
Ward, V., Taylor, B., Murdoch, D., Ekeroma, A., Kirifi-Alai, T. N., Maoate, K., Richards, R., Sika-Paotonu, D., Tong, D., … Wells, B. (2018, November). Strengthening partnerships for Pacific health: Where to from here? [Plenary]. Panel discussion at the Pacific International Health Symposium, Dunedin, New Zealand.
Other Research Output
Sika-Paotonu, D. (2018, October). RE: Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria. Science eLetters. Retrieved from https://immunology.sciencemag.org/content/3/26/eaat7668/tab-e-letters
Sika-Paotonu, D. (2018, October). RE: Type I interferons instigate fetal demise after Zika virus infection. Science eLetters. Retrieved from https://immunology.sciencemag.org/content/3/19/eaao1680/tab-e-letters
Sika-Paotonu, D. (2018, October). RE: PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production. Science eLetters. Retrieved from http://stm.sciencemag.org/content/10/460/eaar8356/tab-e-letters
Sika-Paotonu, D. (2018, October). RE: Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections. Science eLetters. Retrieved from http://stm.sciencemag.org/content/10/460/eaat7520/tab-e-letters
Sika-Paotonu, D. (2018, October). RE: Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumours. Science eLetters. Retrieved from http://science.sciencemag.org/content/359/6371/91/tab-e-letters
Sika-Paotonu, D. (2018, October). IL-25 drives skin inflammation in psoriasis: The potential for clinical utility of IL-25 as a therapeutic target. Science eLetters. Retrieved from http://immunology.sciencemag.org/content/3/23/eaat9662/tab-e-letters
Sika-Paotonu, D. (2018, October). RE: The probacterial effect of type I interferon signaling requires its own negative regulator USP18 . Science eLetters. Retrieved from http://immunology.sciencemag.org/content/3/27/eaau2125/tab-e-letters
2017
Chapter in Book - Research
Sika-Paotonu, D., Beaton, A., Raghu, A., Steer, A., & Carapetis, J. (2017). Acute rheumatic fever and rheumatic heart disease. In J. J. Ferretti, D. L. Stevens & V. A. Fischetti (Eds.), Streptococcus pyogenes: Basic biology to clinical manifestations. (pp. 771-826). Oklahoma, OK: University of Oklahoma Health Sciences Center. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK425394/
Journal - Research Other
Sika-Paotonu, D., Robinson, B., & Maling, T. (2017). Engaging postgraduate students undertaking clinical pharmacology using GoSoapBox for problem-based learning [Syllabus selections: Innovative learning activities]. Journal of Nursing Education, 56(9), 575-576. doi: 10.3928/01484834-20170817-14
Conference Contribution - Published proceedings: Abstract
Sika-Paotonu, D., Tiatia, R., Sung, Y. K., Lander, L., Haira, T., Thornley, C., … Carapetis, J. (2017). The Benzathine Penicillin G (BPG) reformulation preferences study: Towards a new pencillin for rheumatic fever and rheumatic heart disease. Journal of Immunology, 198(1, Suppl.), 213.2. [Abstract]
Sika-Paotonu, D., Viali, S. U., Lameko, V., Bunch, S., Best, K., Fiu, F., … Guilford, P. (2017). Exploring the potential application of ctDNA technology within a resource constrained environment. Journal of Immunology, 198(1, Suppl.), 157.18. [Abstract]
Sika-Paotonu, D., & Guilford, P. (2017). The potential application of ctDNA for improved cancer management, treatment and diagnosis within the Pacific. Journal of Immunology, 198(1, Suppl.), 157.4. [Abstract]
Sika-Paotonu, D., Azevedo, P., Faatoese, A., Wihongi, H., Nuku, H., Hudson, M., … Merriman, T., & Lennon, D. (2017). Culturally appropriate advisory and governance oversight for the study of rheumatic fever and rheumatic heart disease in New Zealand. Journal of Immunology, 198(1, Suppl.), 125.30. [Abstract]
Sika-Paotonu, D., & Laban, L. W. (2017). Cancer immunotherapy: Knowledge translation and outreach education. Journal of Immunology, 198(1, Suppl.), 137.1. [Abstract]
Sika-Paotonu, D., & Tait, C. (2017). Scientific language communication within postgraduate Immunology education. Journal of Immunology, 198(1, Suppl.), 137.2. [Abstract]
Sika-Paotonu, D. (2017). Self-directed learning within postgraduate immunology education. Journal of Immunology, 198(1, Suppl.), 128.5. [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Sika-Paotonu, D. (2017, March). Self-directed learning within postgraduate sciences education for nursing, midwifery and health students. Poster session presented at the 10th Health Disparities Conference, New Orleans, LA.
Sika-Paotonu, D., & Laban, L. W. (2017, March). Increasing awareness of Cancer immunotherapy through knowledge translation and outreach education. Poster session presented at the 10th Health Disparities Conference, New Orleans, LA.
Sika-Paotonu, D. (2017, March). Increasing awareness of scientific concepts by focusing on language communication within postgraduate education. Poster session presented at the 10th Health Disparities Conference, New Orleans, LA.
Sika-Paotonu, D., Viali, S. U., Lameko, V., Burich, S., Best, K., Fiu, F., … Guilford, P. (2017, March). Exploring the potential application of ctDNA technology within a resource constrained environment. Poster session presented at the 10th Health Disparities Conference, New Orleans, LA.
Sika-Paotonu, D., Ulufonua, L., Falevasiva, P., Vaka, E., & Guilford, P. (2017, March). The potential application of ctDNA for improved cancer management, treatment and diagnosis within the Pacific. Poster session presented at the 10th Health Disparities Conference, New Orleans, LA.
Sika-Paotonu, D., Azevedo, P. M., Faatoese, A., Wihongi, H., Nuku, H., Hudson, M., … Merriman, T., & Lennon, D. (2017, March). Culturally appropriate advisory and governance for the study of rheumatic fever and rheumatic heart disease in New Zealand. Poster session presented at the 10th Health Disparities Conference, New Orleans, LA.
Sika-Paotonu, D., Tiatia, R., Thornley, C., Betty, B., Wineera-Parai, R., Eddie, B., Baker, M., … Carapetis, J. (2017, March). The pharmacokinetics of Benzathine Penicillin G (BPG): Towards a new penicillin for rheumatic fever and rheumatic heart disease. Poster session presented at the 10th Health Disparities Conference, New Orleans, LA.
Conference Contribution - Verbal presentation and other Conference outputs
Sika-Paotonu, D. (2017, July). Perspective from a New Zealand member: Victoria University of Wellington. Verbal presentation at the Council of Academic Public Health Institutions Australasia (CAPHIA) Australian Teaching and Learning Forum, Sydney, Australia.
Sika-Paotonu, D., Tiatia, R., Sung, Y. K., Lander, L., Haira, T., Thornley, C., … Baker, M., … Carapetis, J. (2017, March). The Benzathine Penicillin G (BPG) Reformulation Preferences Study: Towards a new penicillin for rheumatic fever and rheumatic heart disease. Verbal presentation at the 10th Health Disparities Conference, New Orleans, LA.
Other Research Output
Sika-Paotonu, D. (2017, April). RE: The challenges of work-life balance within the scientific and academic research domains. Science eLetters. Retrieved from http://science.sciencemag.org/content/354/6319/1666/tab-e-letters
Sika-Paotonu, D. (2017, April). RE: Pathways for women into scientific research. Science eLetters. Retrieved from http://science.sciencemag.org/content/354/6317/1346/tab-e-letters
Sika-Paotonu, D. (2017, January). RE: Scientific endeavours, cultural perspectives and considerations: Learning from other cultures. Science eLetters. Retrieved from http://science.sciencemag.org/content/345/6198/842/tab-e-letters
Sika-Paotonu, D. (2017, January). RE: Scientific education, educators and the importance of student learning: Lessons for all. Science eLetters. Retrieved from http://science.sciencemag.org/content/345/6202/1414/tab-e-letters
Sika-Paotonu, D. (2017, January). RE: Reducing the risk of non-reproducibility within the computational science context: Important lessons for all. Science eLetters. Retrieved from http://science.sciencemag.org/content/354/6308/142/tab-e-letters
Sika-Paotonu, D. (2017, January). RE: Success within the scientific research and academic environment. Science eLetters. Retrieved from http://science.sciencemag.org/content/353/6294/94/tab-e-letters
Sika-Paotonu, D. (2017, January). RE: The 1-hour workday. Science eLetters. Retrieved from http://science.sciencemag.org/content/353/6300/718/tab-e-letters
Sika-Paotonu, D. (2017, January). RE: A researcher discovers teaching. Science eLetters. Retrieved from http://science.sciencemag.org/content/352/6282/262/tab-e-letters
Sika-Paotonu, D. (2017, January). RE: The borders I crossed: An inspiration to others. Science eLetters. Retrieved from http://science.sciencemag.org/content/345/6204/1650/tab-e-letters
Sika-Paotonu, D. (2017, January). RE: Doing science - as a professor of comparative genomics. Science eLetters. Retrieved from http://science.sciencemag.org/content/353/6307/1586/tab-e-letters
Sika-Paotonu, D. (2017, April). RE: Supporting scientific research endeavours. Science eLetters. Retrieved from http://science.sciencemag.org/content/353/6302/954/tab-e-letters
Sika-Paotonu, D. (2017, April). RE: Collaboration success factors within the Scientific environment. Science eLetters. Retrieved from http://science.sciencemag.org/content/349/6246/446/tab-e-letters
Sika-Paotonu, D. (2017, April). RE: The value of a broad foundational knowledge base within the laboratory setting. Science eLetters. Retrieved from http://science.sciencemag.org/content/355/6329/1090/tab-e-letters
Sika-Paotonu, D. (2017, April). RE: A combinatorial approach: the modulation of CXCR2-mediated MDSC tumour trafficking to enhance anti-PD1 checkpoint blockade. Response to Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 Efficacy. Science eLetters. Retrieved from http://stm.sciencemag.org/content/6/237/237ra67/tab-e-letters
Sika-Paotonu, D. (2017, September). Response to STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade. Science eLetters. Retrieved from http://stm.sciencemag.org/content/7/283/283ra52/tab-e-letters
Sika-Paotonu, D., Tiatia, R. (2017, January). RE: Diversity, relationships and team building–towards powerful research collaboration. Response to Orchestrating a powerful group. Science eLetters. Retrieved from http://science.sciencemag.org/content/352/6283/378/tab-e-letters
2016
Journal - Research Article
Cornwall, J., Robinson, B., & Sika-Paotonu, D. (2016). The availability of clinical anatomy in postgraduate nursing education in New Zealand. Anatomy, 10(2), 138-142. doi: 10.2399/ana.16.022
Conference Contribution - Published proceedings: Abstract
Sika-Paotonu, D., Marsh, J., Gray, K., Bowen, A., Carapetis, J., Salman, S., … Ramsay, J. (2016). Understanding protective plasma levels of penicillin and monitoring antibody responses for the prevention of GAS infection in a pediatric population. European Journal of Immunology, 46(Suppl. 1), (pp. 619). doi: 10.1002/eji.201670200
Sika-Paotonu, D. (2016). Immunology education within a Postgraduate Nursing Science program in New Zealand. Journal of Immunology, 196(1, Suppl.), 130.8. [Abstract]
Cornwall, J., Robinson, B., & Sika-Paotonu, D. (2016). Is clinical anatomy and science-based education readily available in postgraduate nursing education frameworks in New Zealand? Clinical Anatomy, (pp. 221). doi: 10.1002/ca.22682
Azevedo, P., Merriman, T., Topless, R., Sika-Paotonu, D., Crengle, S., Wilson, N., … Lennon, D. (2016). Association study involving polymorphisms in IL-6, IL1-RA, and CTLA4 genes and rheumatic heart disease in New Zealand population of Māori and Pacific ancestry. European Journal of Immunology, 46(Suppl. 1), (pp. 288). doi: 10.1002/eji.201670200
Working Paper; Discussion Paper; Technical Report
Wyber, R., Johnson, T., Carapetis, J., Davis, K., Gray, K., Marantelli, S., … Sika-Paotonu, D., … Zühlke, L. (2016). Global status of BPG report: The Benzathine Penicillin G report. RHD Action. 52p. Retrieved from http://rhdaction.org
Other Research Output
Sika-Paotonu, D. (2016, December). RE: Living up to my mentors. Science eLetters. Retrieved from http://science.sciencemag.org/content/354/6318/1494/tab-e-letters
Sika-Paotonu, D. (2016, December). RE: Three lessons rarely taught: In pursuit of research success. Science eLetters. Retrieved from http://science.sciencemag.org/content/352/6291/1358/tab-e-letters
Sika-Paotonu, D. (2016, December). RE: Alternatives within academia: Research and teaching contributions within the academic landscape. Science eLetters. Retrieved from http://science.sciencemag.org/content/353/6297/418/tab-e-letters
Sika-Paotonu, D. (2016, December). Response to A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells. Science eLetters. Retrieved from http://science.sciencemag.org/content/348/6236/803/tab-e-letters
Sika-Paotonu, D. (2016, December). RE: Anti–CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response. Science eLetters. Retrieved from http://stm.sciencemag.org/content/6/254/254ra128/tab-e-letters
2014
Awarded Doctoral Degree
Sika-Paotonu, D. (2014). Increasing the potency of dendritic cell based vaccines for the treatment of cancer (PhD). Victoria University of Wellington, Wellington, New Zealand. 379p. Retrieved from https://viewer.waireto.victoria.ac.nz/client/viewer/IE960844/details?dps_dvs=1524436811973~298
2012
Conference Contribution - Verbal presentation and other Conference outputs
Sika-Paotonu, D. (2012, February). Designing vaccines to combat cancer: A pacific journey through the New Zealand science, health and research communities [Invited]. Workshop presentation at the Asia-Pacific Science, Technology and Society Network (APSTSN) Workshop, Wellington, New Zealand.
2011
Journal - Research Article
Petersen, T. R., Sika-Paotonu, D., Knight, D. A., Simkins, H. M. A., & Hermans, I. F. (2011). Exploiting the role of endogenous lymphoid-resident dendritic cells in the priming of NKT cells and CD8+ T cells to dendritic cell-based vaccines. PLoS ONE, 6(3), e17657. doi: 10.1371/journal.pone.0017657
Delahunt, B., Sika-Paotonu, D., Bethwaite, P. B., Jordan, T. W., Magi-Galluzzi, C., Zhou, M., … Srigley, J. R. (2011). Grading of clear cell renal cell carcinoma should be based on nucleolar prominence. American Journal of Surgical Pathology, 35(8), 1134-1139. doi: 10.1097/PAS.0b013e318220697f
Commissioned Report for External Body
Sika-Paotonu, D., Smith, L., Tibby, C., & McDuff, I. (2011). A dynamic evidence-base: Service and clinical quality initiatives addressing Pacific Peoples' health needs. Commissioned by Ministry of Health. Wellington, New Zealand: Litmus. 48p. Retrieved from https://litmus.co.nz
2010
Journal - Research Article
Petersen, T. R., Sika-Paotonu, D., Knight, D. A., Dickgreber, N., Farrand, K. J., Ronchese, F., & Hermans, I. F. (2010). Potent anti-tumor responses to immunization with dendritic cells loaded with tumor tissue and an NKT cell ligand. Immunology & Cell Biology, 88(5), 596-604. doi: 10.1038/icb.2010.9
Journal - Research Other
Delahunt, B., Bethwaite, P. B., Miller, R. J., Sika-Paotonu, D., & Srigley, J. R. (2010). Re: Fuhrman grade provides higher prognostic accuracy than nucleolar grade for papillary renal cell carcinoma [Letter to the editor/errata]. Journal of Urology, 185(1), 356-357. doi: 10.1016/j.juro.2010.08.045
2007
Journal - Research Article
Delahunt, B., Sika-Paotonu, D., Bethwaite, P. B., McCredie, M. R. E., Martignoni, G., Eble, J., & Jordan, T. W. (2007). Fuhrman grading is not appropriate for chromophobe renal cell carcinoma. American Journal of Surgical Pathology, 31(6), 957-960.
Awarded Masters Degree
Sika-Paotonu, D. (2007). Assessment of the utility of the Fuhrman grading system for the major subtypes of renal cell carcinoma (M.Bio.Sci.(Hons.)). Victoria University of Wellington, Wellington, New Zealand.
2006
Journal - Research Article
Sika-Paotonu, D., Bethwaite, P. B., McCredie, M. R. E., William, J. T., & Delahunt, B. (2006). Nucleolar grade but not Fuhrman grade is applicable to papillary renal cell carcinoma. American Journal of Surgical Pathology, 30(9), 1091-1096. doi: 10.1097/01.pas.0000209833.69972.2b