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Contact Details

Phone
(Teams): 975 6027
Email
joe.yip@otago.ac.nz
Position
Research Fellow
Department
Department of Anatomy
Qualifications
PhD
Research summary
Neuroendocrinology

Research

My research focuses on the neuronal plasticity induced by reproductive hormones, and how this contributes to reproductive function. Using a wide range of anatomical and functional neuroscience tools in transgenic rodent models, I study the neurochemical, morphological and behavioural characteristics of the tuberoinfundibular dopaminergic (TIDA) neurons relevant to maternal adaptation. I am particularly interested in understanding the mechanism underlying the plasticity of TIDA neurons to alter prolactin secretion especially to allow elevated levels critical for lactation.

Yip, S. H., Boehm, U., Herbison, A. E., & Campbell, R. E. (2015). Conditional viral tract tracing delineates the projections of the distinct kisspeptin neuron populations to gonadotropin-releasing hormone (GnRH) neurons in the mouse. Endocrinology, 156(7), 2582-2594. doi: 10.1210/en.2015-1131 Journal - Research Article

Yip, S. H., Eguchi, R., Grattan, D. R., & Bunn, S. J. (2012). Prolactin signalling in the mouse hypothalamus is primarily mediated by signal transducer and activator of transcription factor 5b but not 5a. Journal of Neuroendocrinology, 24(12), 1484-1491. doi: 10.1111/j.1365-2826.2012.02357.x Journal - Research Article

Romanò, N., Yip, S. H., Hodson, D. J., Guillou, A., Parnaudeau, S., Kirk, S., … Bunn, S. J., Grattan, D. R., … Martin, A. O. (2013). Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release. Journal of Neuroscience, 33(10), 4424-4433. doi: 10.1523/jneurosci.4415-12.2013 Journal - Research Article

Moore, A. M., Prescott, M., Marshall, C. J., Yip, S. H., & Campbell, R. E. (2015). Enhancement of a robust arcuate GABAergic input to gonadotropin-releasing hormone neurons in a model of polycystic ovarian syndrome. PNAS, 112(2), 596-601. doi: 10.1073/pnas.1415038112 Journal - Research Article

Brown, R. S. E., Kokay, I. C., Phillipps, H. R., Yip, S. H., Gustafson, P., Wyatt, A., Larsen, C. M., Knowles, P., Ladyman, S. R., LeTissier, P., & Grattan, D. R. (2016). Conditional deletion of the prolactin receptor reveals functional subpopulations of dopamine neurons in the arcuate nucleus of the hypothalamus. Journal of Neuroscience, 36(35), 9173-9185. doi: 10.1523/jneurosci.1471-16.2016 Journal - Research Article

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