Contact Details
University Links
- Position
- PhD Student
- Department
- Department of Anatomy
- Qualifications
- BSc (Genetics)
- Research summary
- Investigating candidate genes for mammalian Gene Drive pest control
Research
Recent discovery of CRISPR gene editing has enabled further exploration of Gene Drive techniques for pest species control and eradication. Based on the idea of super-Mendelian inheritance, species populations could be humanely controlled by introduced sex-biased infertility genes.
Most research has been focused on reviewing system models as a whole so we aim to investigate candidate genes. Application could have the potential to be a long term solution to aid conservation both here in New Zealand and overseas.
Publications
Clark, A. C., Edison, R., Esvelt, K., Kamau, S., Dutoit, L., Champer, J., … Alexander, A., & Gemmell, N. J. (2024). A framework for identifying fertility gene targets for mammalian pest control. Molecular Ecology Resources, 24(2), e13901. doi: 10.1111/1755-0998.13901 Journal - Research Article
Clark, A. C., Messer, P. W., Alexander, A., & Gemmell, N. J. (2023, August-September). Exploring outcomes of genetic pest control in multi-species models. Verbal presentation at the He taonga tuku iho: Queenstown Molecular Biology (QMB) Bioprotection Aotearoa Satellite, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs
Taitingfong, R. I., Triplett, C., Vásquez, V. N., Rajagopalan, R. M., Raban, R., Roberts, A., … Clark, A., … Bloss, C. S. (2023). Exploring the value of a global gene drive project registry. Nature Biotechnology, 41, 9-13. doi: 10.1038/s41587-022-01591-w Journal - Research Other
Forsdick, N. J., Adams, C. I. M., Alexander, A., Clark, A. C., Collier-Robinson, L., Cubrinovska, I., … Dowle, E. J., … Verry, A. J. F., … Steeves, T. E. (2022). Current applications and future promise of genetic/genomic data for conservation in an Aotearoa New Zealand context (Science for Conservation 337). Commissioned by Department of Conservation (DOC). Wellington, New Zealand: Department of Conservation Te Papa Atawhai. 57p. Retrieved from https://www.doc.govt.nz/about-us/science-publications/series/science-for-conservation Commissioned Report for External Body