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Contact Details

+64 3 479 8460
Senior Research Fellow
Department of Anatomy
BSc (Hons) PhD
Research summary
Memory and Alzheimer's disease


Memory loss arising from neurodegenerative diseases such as Alzheimer's disease is devastating both to the individual and to their loved ones, robbing the individual of many of his/her uniquely identifiable characteristics. Dr Ryan's interest is in how memories are formed and stored in the brain at the molecular level and how this may be altered in Alzheimer's disease.


Mockett, B. G., & Ryan, M. M. (2023). The therapeutic potential of the neuroactive peptides of soluble amyloid precursor protein-alpha in Alzheimer’s disease and related neurological disorders. Seminars in Cell & Developmental Biology, 139, 93-101. doi: 10.1016/j.semcdb.2022.05.014 Journal - Research Other

Cawood, S., Neehoff, S., Glue, P., Williams, J., Ryan, M., Russell, B., & Harrison, O. (2022). Investigating the relationship between microRNA expression, brain structure and biochemistry in anxiety disorders and their potential treatment with ketamine. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 82). Retrieved from Conference Contribution - Published proceedings: Abstract

Ryan, M., Tan, V. T. Y., Thompson, N., Guévremont, D., Mockett, B. G., Tate, W. P., Abraham, W. C., Hughes, S. M., & Williams, J. (2021). Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha promotes long-term induction of neuroprotective genes and pathways in a mouse model of Alzheimer’s disease. Journal of Alzheimer's Disease, 79, 1075-1090. doi: 10.3233/JAD-200757 Journal - Research Article

Sweetman, E., Noble, A., Edgar, C., Mackay, A., Helliwell, A., Vallings, R., Ryan, M., & Tate, W. (2019). Current research provides insight into the biological basis and diagnostic potential for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Diagnostics, 9(3), 73. doi: 10.3390/diagnostics9030073 Journal - Research Other

Sweetman, E., Ryan, M., Edgar, C., MacKay, A., Vallings, R., & Tate, W. (2019). Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndrome. International Journal of Immunopathology & Pharmacology, 33, 1-8. doi: 10.1177/2058738418820402 Journal - Research Article

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