Dr Sharon Ladyman

2025

Journal - Research Article

Hackwell, E., Ladyman, S. R., Clarkson, J., McQuillan, H. J., Boehm, U., Herbison, A. E., Brown, R. S. E., & Grattan, D. R. (2025). Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice. eLIFE, 13, RP94570. doi: 10.7554/eLife.94570.3

Ladyman, S. R., Georgescu, T. R., Stewart, A. M., Khant Aung, Z., Cheong, I., Grattan, D. R., & Brown, R. S. E. (2025). Prolactin modulation of thermoregulatory circuits provides resilience to thermal challenge of pregnancy. Cell Reports, 44(4), 115567. doi: 10.1016/j.celrep.2025.115567

2024

Chapter in Book - Research

Ladyman, S. R., & Woodside, B. C. (2024). Adaptations of the maternal brain to meet the increased energy demands of pregnancy and lactation. In P. J. Brunton & D. R. Grattan (Eds.), Neuroendocrine regulation of mammalian pregnancy and lactation. (pp. 65-92). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-51138-7_3

Grattan, D. R., & Ladyman, S. R. (2024). Maternal recognition of pregnancy. In P. J. Brunton & D. R. Grattan (Eds.), Neuroendocrine regulation of mammalian pregnancy and lactation. (pp. 1-20). Cham, Switzerland: Springer. doi: 10.1007/978-3-031-51138-7_1

Journal - Research Article

Khant Aung, Z., Ladyman, S. R., & Brown, R. S. E. (2024). Transient loss of satiety effects of leptin in middle-aged male mice. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13386

Clarke, G. S., Vincent, A. D., Ladyman, S. R., Gatford, K. L., & Page, A. J. (2024). Circadian patterns of behaviour change during pregnancy in mice. Journal of Physiology. Advance online publication. doi: 10.1113/JP285553

Clarke, G. S., Li, H., Ladyman, S. R., Young, R. L., Gatford, K. L., & Page, A. J. (2024). Effect of pregnancy on the expression of nutrient-sensors and satiety hormones in mice. Peptides, 172, 171114. doi: 10.1016/j.peptides.2023.171114

Conference Contribution - Poster Presentation (not in published proceedings)

Cross, A. N., Khant Aung, Z., & Ladyman, S. R. (2024, August-September). Role of prolactin sensitive POA to VTA pathway in suppression of running wheel activity during early pregnancy. Poster session presented at the 18th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Georgescu, T., Stewart, A. M., Sawyer, I. L., Gillett, M. L., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2024, August-September). Investigating the role of prolactin in pregnancy-associated thermoregulatory changes. Verbal presentation at the 18th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Boer, G. A., Rizwan, M. Z., Ladyman, S., Garratt, M., & Tups, A. (2024, August-September). Control of energy balance by hypothalamic and hindbrain GIP receptors. Verbal presentation at the 18th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2023

Journal - Research Article

Brown, R. S. E., Jacobs, I. M., Khant Aung, Z., Knowles, P. J., Grattan, D. R., & Ladyman, S. R. (2023). High fat diet-induced maternal obesity in mice impairs peripartum maternal behaviour. Journal of Neuroendocrinology, 35, e13350. doi: 10.1111/jne.13350

Garratt, M., Neyt, C., Ladyman, S. R., Pyrski, M., Zufall, F., & Leinders-Zufall, T. (2023). Sensory detection of female olfactory cues as a central regulator of energy metabolism and body weight in male mice. iScience, 26, 106455. doi: 10.1016/j.isci.2023.106455

Hackwell, E. C. R., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2023). Mechanisms of lactation-induced infertility in female mice. Endocrinology, 164(5), bqad049. doi: 10.1210/endocr/bqad049

Swart, J. M., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2023). Pups and prolactin are rewarding to virgin female and pregnant mice. Journal of Neuroendocrinology, 35, e13232. doi: 10.1111/jne.13232

Conference Contribution - Published proceedings: Abstract

Murrell, C. L., Andrews, Z. B., Grattan, D. R., & Ladyman, S. R. (2023). Insensitivity to the feeding response of exogenous ghrelin develops during pregnancy. Proceedings of the Society for Neuroscience Annual Meeting. PSTR286.14/KK2. Retrieved from https://www.sfn.org/

Conference Contribution - Poster Presentation (not in published proceedings)

Murrell, C. L., Andrews, Z. B., Grattan, D. R., & Ladyman, S. R. (2023, August). Adaptations in the AgRP neuron responses to ghrelin do not under pregnancy-induced ghrelin insensitivity. Poster session presented at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Murrell, C. L., Andrews, Z. B., Grattan, D. R., & Ladyman, S. R. (2023, August). Insensitivity to ghrelin-induced food intake occurs during pregnancy and is not driven by AgRP neuron desensitisation. Poster session presented at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Georgescu, T., Sawyer, I., Gillett, M., Stewart, A., Ladyman, S. R., & Grattan, D. R. (2023, August). Suppression of fever, but not sickness behaviours in late pregnancy in mice [Award lecture]. Verbal presentation at the Brain Health Research Centre (BHRC) Annual Conference, Dunedin, New Zealand.

Murrell, C. L., Andrews, Z. B., Grattan, D. R., & Ladyman, S. (2023, August-September). AgRP neuron activity throughout the estrus cycle. Verbal presentation at the Queenstown Molecular Biology (QMB) Hypothalamic Neuroscience & Neuroendocrinology Australasia (HNNA) Satellite, Queenstown, New Zealand.

Murrell, C. L., Andrews, Z. B., Grattan, D. R., & Ladyman, S. R. (2023, August). AgRP neuron activity throughout pregnancy. Verbal presentation at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2022

Conference Contribution - Published proceedings: Abstract

Young, C. D., Grattan, D. R., & Ladyman, S. (2022). The effect of a Polynesian-specific CREBRF gene variant on pregnancy hormones in a mouse model. In A. Finigan, R. Richards & P. Vakaoti (Eds.), Proceedings of the Pacific Postgraduate Symposium: Pacific Voices XIX. (pp. 39). Dunedin, New Zealand: Pacific Islands Centre, University of Otago. Retrieved from http://hdl.handle.net/10523/16237

Clarke, G. S., Ladyman, S. R., Young, R. L., Gatford, K. L., & Page, A. J. (2022). Circadian variations in food intake during pregnancy in mice. Obesity Reviews, 23(Suppl. 2), (pp. 4-5). doi: 10.1111/obr.13503

Young, C., Grattan, D., & Ladyman, S. (2022). Effect of the Polynesian-specific CREBRF gene variant on lactogenic activity during mouse pregnancy. Proceedings of the joint ESA-SRB-APEG-NZSE Annual Scientific Meeting. 139. Retrieved from https://www.esa-srb-apeg-nzse.org

Ladyman, S. R. (2022). Prolactin modulation of thermoregulatory circuits provides resilience to thermal challenge of pregnancy and lactation. Proceedings of the joint ESA-SRB-APEG-NZSE Annual Scientific Meeting. 223. Retrieved from https://www.esa-srb-apeg-nzse.org

Hackwell, E. C. R., Ladyman, S. R., Brown, R. S. E., Herbison, A. E., & Grattan, D. R. (2022). Prolactin-induced suppression of gonadotrophin secretion during lactation. Proceedings of the joint ESA-SRB-APEG-NZSE Annual Scientific Meeting. 240. Retrieved from https://www.esa-srb-apeg-nzse.org

Gillett, M. L., Grattan, D. R., & Ladyman, S. R. (2022). The role of prolactin in the small intestine during pregnancy and lactation. New Zealand Medical Journal, 135(1557), (pp. 102). Retrieved from https://journal.nzma.org.nz/

Conference Contribution - Verbal presentation and other Conference outputs

Khant Aung, Z., Kado, E., Young, C., Grattan, D. R., & Ladyman, S. R. (2022, August). Protective role of a Polynesian-specific variant of CREBRF gene against gestational diabetes mellitus (GDM): Mouse model. Verbal presentation at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

Ladyman, S. R. (2022, August-September). Long term impact of pregnancy and lactation on the regulation of energy balance in female mice. Verbal presentation at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Murrell, C. L., Grattan, D. R., & Ladyman, S. R. (2022, August-September). Ghrelin-induced food intake is supressed during pregnancy and restored lactation. Verbal presentation at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Gillett, M. L., Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2022, August-September). Prolactin receptors in the epithelial cells of the intestine influence feeding patterns in pregnancy. Verbal presentation at the 16th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2021

Journal - Research Article

Khant Aung, Z., Kokay, I. C., Grattan, D. R., & Ladyman, S. R. (2021). Prolactin-induced adaptation in glucose homeostasis in mouse pregnancy is mediated by the pancreas and not in the forebrain. Frontiers in Endocrinology, 12, 765976. doi: 10.3389/fendo.2021.765976

Ladyman, S. R., Larsen, C. M., Taylor, R. S., Grattan, D. R., & McCowan, L. M. E. (2021). Case–control study of prolactin and placental lactogen in SGA pregnancies. Reproduction & Fertility, 2(4), 244-250. doi: 10.1530/RAF-21-0020

Ladyman, S. R., Carter, K. M., Gillett, M. L., Khant Aung, Z., & Grattan, D. R. (2021). A reduction in voluntary physical activity in early pregnancy in mice is mediated by prolactin. eLIFE, 10, e62260. doi: 10.7554/eLife.62260

Swart, J. M., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2021). Changes in maternal motivation across reproductive states in mice: A role for prolactin receptor activation on GABA neurons. Hormones & Behavior, 135, 105041. doi: 10.1016/j.yhbeh.2021.105041

Ladyman, S. R., & Brooks, V. L. (2021). Central actions of insulin during pregnancy and lactation [Invited review]. Journal of Neuroendocrinology, 33, e12946. doi: 10.1111/jne.12946

Journal - Research Other

Clarke, G. S., Gatford, K. L., Young, R. L., Grattan, D. R., Ladyman, S. R., & Page, A. J. (2021). Maternal adaptations to food intake across pregnancy: Central and peripheral mechanisms. Obesity, 29(11), 1813-1824. doi: 10.1002/oby.23224

2020

Chapter in Book - Research

Grattan, D. R., & Ladyman, S. R. (2020). Neurophysiological and cognitive changes in pregnancy. In E. A. P. Steegers, M. J. Cipolla & E. C. Miller (Eds.), Handbook of clinical neurology (Vol. 171): Neurology and pregnancy: Pathophysiology and patient care. (pp. 25-55). Amsterdam, The Netherlands: Elsevier. doi: 10.1016/B978-0-444-64239-4.00002-3

Journal - Research Article

Georgescu, T., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2020). Acute effects of prolactin on hypothalamic prolactin receptor expressing neurones in the mouse. Journal of Neuroendocrinology, 32, e12908. doi: 10.1111/jne.12908

Gustafson, P., Ladyman, S. R., McFadden, S., Larsen, C., Khant Aung, Z., Brown, R. S. E., Bunn, S. J., & Grattan, D. R. (2020). Prolactin receptor-mediated activation of pSTAT5 in the pregnant mouse brain. Journal of Neuroendocrinology, 32, e12901. doi: 10.1111/jne.12901

Barad, Z., Khant Aung, Z., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2020). Impaired prolactin transport into the brain and functional responses to prolactin in aged male mice. Journal of Neuroendocrinology, 32, e12889. doi: 10.1111/jne.12889

Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2020). Pregnancy-induced adaptation of central sensitivity to leptin and insulin. Molecular & Cellular Endocrinology, 516, 110933. doi: 10.1016/j.mce.2020.110933

Lopez-Vicchi, F., Ladyman, S. R., Ornstein, A. M., Gustafson, P., Knowles, P., Luque, G. M., Grattan, D. R., & Becu-Villalobos, D. (2020). Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake. FASEB Journal, 34, 3902-3914. doi: 10.1096/fj.201902357R

Journal - Research Other

Lopez-Vicchi, F., De Winne, C., Brie, B., Sorianello, E., Ladyman, S. R., & Becu-Villalobos, D. (2020). Metabolic functions of prolactin: Physiological and pathological aspects. Journal of Neuroendocrinology, 32, e12888. doi: 10.1111/jne.12888

Ladyman, S. R., Hackwell, E. C. R., & Brown, R. S. E. (2020). The role of prolactin in co-ordinating fertility and metabolic adaptations during reproduction. Neuropharmacology, 167, 107911. doi: 10.1016/j.neuropharm.2019.107911

Conference Contribution - Published proceedings: Abstract

Swart, J. M., Ladyman, S. R., Grattan, D. R., & Brown, R. S. E. (2020). Identifying a role for lactogenic hormones in maternal motivation. Journal of the Endocrine Society, 4(Suppl. 1), (pp. A1075). doi: 10.1210/jendso/bvaa046.2131

2019

Chapter in Book - Research

Smiley, K. O., Ladyman, S. R., Gustafson, P., Grattan, D. R., & Brown, R. S. E. (2019). Neuroendocrinology and adaptive physiology of maternal care. In L. M. Coolen & D. R. Grattan (Eds.), Neuroendocrine regulation of behavior: Current topics in behavioral neurosciences (Vol. 43). (pp. 161-210). Cham, Switzerland: Springer. doi: 10.1007/7854_2019_122

Journal - Research Article

Gustafson, P., Ladyman, S. R., & Brown, R. S. E. (2019). Suppression of leptin transport into the brain contributes to leptin resistance during pregnancy in the mouse. Endocrinology, 160(4), 880-890. doi: 10.1210/en.2018-01065

Augustine, R. A., Knowles, P. J., Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2019). Impaired hypothalamic leptin sensitivity in pseudopregnant rats treated with chronic prolactin to mimic pregnancy. Journal of Neuroendocrinology, 31, e12702. doi: 10.1111/jne.12702

Aquino, N. S. S., Kokay, I. C., Perez, C. T., Ladyman, S. R., Henriques, P. C., Silva, J. F., … Grattan, D. R., & Szawka, R. E. (2019). Kisspeptin stimulation of prolactin secretion requires Kiss1 receptor but not in tuberoinfundibular dopaminergic neurons. Endocrinology, 160(3), 522-533. doi: 10.1210/en.2018-00932

Journal - Research Other

Ladyman, S. R. (2019). Anticipating future demands: Hormone-induced transcriptional programming in the maternal pancreas during pregnancy. Endocrinology, 160(5), 1164-1165. doi: 10.1210/en.2019-00243

Conference Contribution - Poster Presentation (not in published proceedings)

Khant Aung, Z., Jacobs, I., Grattan, D. R., Brown, R. S. E., & Ladyman, S. R. (2019, August-September). Peripartum prolactin and growth hormone concentrations in diet-induced obese mice. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Hackwell, E. C. R., Brown, R. S. E., Ladyman, S. R., & Grattan, D. R. (2019, August-September). Prolactin action on kisspeptin neurons is required for maintaining lactational infertility. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Ladyman, S. R., & Grattan, D. R. (2019, September). Contribution of central prolactin receptors to changes in energy homeostasis during pregnancy and lactation. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Swart, J. M., Ladyman, S. R., Grattan, D. R., & Brown, R. S. E. (2019, September). The effect of reproductive experience on maternal motivation. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Georgescu, T., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2019, August-September). Investigating the acute effects of prolactin upon hypothalamic prolactin-receptor expressing neurons. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2018

Journal - Research Article

McEwen, H. J. L., Cognard, E., Ladyman, S. R., Khant-Aung, Z., Tups, A., Shepherd, P. R., & Grattan, D. R. (2018). Feeding and GLP-1 receptor activation stabilize beta-catenin in specific hypothalamic nuclei in male rats. Journal of Neuroendocrinology, 30(6), e12607, 1-10. doi: 10.1111/jne.12607

Ladyman, S. R., Carter, K. M., & Grattan, D. R. (2018). Energy homeostasis and running wheel activity during pregnancy in the mouse. Physiology & Behavior, 194, 83-94. doi: 10.1016/j.physbeh.2018.05.002

Ladyman, S. R., Khant Aung, Z., & Grattan, D. R. (2018). Impact of pregnancy and lactation on the long-term regulation of energy balance in female mice. Endocrinology, 159(6), 2324-2336. doi: 10.1210/en.2018-00057

Conference Contribution - Published proceedings: Abstract

Ladyman, S. R., Khant Aung, Z., & Grattan, D. R. (2018). Pregnancy-induced adaptations in glucose homeostasis in the mouse requires prolactin receptor expression in the pancreas but not the brain. Endocrine Reviews, 39(2), MON-150. [Abstract]

Lopez-Vicchi, F., Ladyman, S. R., Ornstein, A. M., Luque, G. M., Grattan, D. R., & Becu-Villalobus, D. (2018). Leptin insensitivity and nuclei-specific altered gene expression in hypothalamus of trransgenic mice with chronic hyperprolactinemia. Endocrine Reviews, 39(2), SAT-623-LB. [Abstract]

Khant Aung, Z., Grattan, D., & Ladyman, S. R. (2018). Long-term consequences of reproductive experience on metabolic homeostasis in mothers. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 214). Retrieved from http://www.icn2018.org/

Ladyman, S., Carter, K. M., & Grattan, D. (2018). Prolactin drives the decreases in voluntary physical activity in early pregnancy. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 173). Retrieved from http://www.icn2018.org/

Gustafson, P., Ladyman, S. R., Grattan, D., & Brown, R. S. E. (2018). Changing dynamics of prolactin and leptin transport into the brain during pregnancy and with aging. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 124). Retrieved from http://www.icn2018.org/

Conference Contribution - Poster Presentation (not in published proceedings)

Hackwell, E. C. R., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2018, November). Central prolactin action is required for maintaining lactational diestrus in mice. Poster session presented at the Women’s Wellbeing Symposium, Dunedin, New Zealand.

Carter, K. M., Grattan, D. R., & Ladyman, S. R. (2018, November). Prolactin acutely influences running wheel activity but not ambulatory activity in female mice. Poster session presented at the Women’s Wellbeing Symposium, Dunedin, New Zealand.

Jacobs, I., Brown, R. S. E., Grattan, D. R., & Ladyman, S. R. (2018, November). Are impairments in prolactin signalling in the brain of obese mice associated with deficits in maternal care? Poster session presented at the Women’s Wellbeing Symposium, Dunedin, New Zealand.

Ladyman, S. R., & Grattan, D. R. (2018, November). Pregnancy and lactation lead to long term changes in body weight and small intestine length in female mice. Poster session presented at the Women’s Wellbeing Symposium, Dunedin, New Zealand.

Carter, K. M., Grattan, D. R., & Ladyman, S. R. (2018, August). Prolactin acutely influences running wheel activity but not ambulatory activity in female mice. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Khant Aung, Z., Ladyman, S. R., & Grattan, D. R. (2018, August). Central prolactin receptor activation contributes to the hyperphagia of lactation. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Khant Aung, Z., Ladyman, S. R., & Grattan, D. R. (2018, November). Central prolactin receptor activition contributes to the hyperphagia of lactation. Poster session presented at the Women’s Wellbeing Symposium, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Tawngdee, Y., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2018, August). The role of prolactin in reward aspects of maternal behaviour. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Jacobs, I., Brown, R. S. E., Grattan, D. R., & Ladyman, S. R. (2018, August). Are impairments in prolactin signaling in the brain of obese mice associated with deficits in maternal care? Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Hackwell, E. C. R., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2018, August). Central prolactin action is required for maintaining lactational diestrus in mice. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2017

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2017). Region-specific suppression of hypothalamic responses to insulin to adapt to elevated maternal insulin secretion during pregnancy. Endocrinology, 158(12), 4257-4269. doi: 10.1210/en.2017-00600

Brown, R. S. E., Aoki, M., Ladyman, S. R., Phillipps, H. R., Wyatt, A., Boehm, U., & Grattan, D. R. (2017). Prolactin action in the medial preoptic area is necessary for postpartum maternal nursing behavior. PNAS, 114(40), 10779-10784. doi: 10.1073/pnas.1708025114

Ladyman, S. R., MacLeod, M. A., Khant Aung, Z., Knowles, P., Phillipps, H. R., Brown, R. S. E., & Grattan, D. R. (2017). Prolactin receptors in Rip-cre cells, but not in AgRP neurons, are involved in energy homeostasis. Journal of Neuroendocrinology, 29(10), e12474. doi: 10.1111/jne.12474

Tups, A., Benzler, J., Sergi, D., Ladyman, S. R., & Williams, L. M. (2017). Central regulation of glucose homeostasis. Comprehensive Physiology, 7(2), 741-764. doi: 10.1002/cphy.c160015

Augustine, R. A., Ladyman, S. R., Bouwer, G. T., Alyousif, Y., Sapsford, T. J., Scott, V., Kokay, I. C., Grattan, D. R., & Brown, C. H. (2017). Prolactin regulation of oxytocin neurone activity in pregnancy and lactation. Journal of Physiology, 595(11), 3591-3605. doi: 10.1113/jp273712

Conference Contribution - Published proceedings: Abstract

Carter, K. M., Grattan, D. R., & Ladyman, S. R. (2017). Prolactin acutely influences running wheel activity but not ambulatory activity in female mice. Proceedings of the Australasian Neuroscience Society 37th Annual Scientific Meeting. Retrieved from http://ans2017.aomevents.com.au

Conference Contribution - Poster Presentation (not in published proceedings)

Khant Aung, Z., Ladyman, S. R., & Grattan, D. R. (2017, September). Pregnancy-induced adaptations in glucose homeostasis in the mouse requires prolactin receptor expression in the pancreas but not the brain. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Carter, K., Grattan, D. R., & Ladyman, S. R. (2017, September). Prolactin-induced suppression of acute running wheel activity in female mice. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2016

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2016). Central effects of leptin on glucose homeostasis are modified during pregnancy in the rat. Journal of Neuroendocrinology, 28(10). doi: 10.1111/jne.12431

Brown, R. S. E., Kokay, I. C., Phillipps, H. R., Yip, S. H., Gustafson, P., Wyatt, A., Larsen, C. M., Knowles, P., Ladyman, S. R., LeTissier, P., & Grattan, D. R. (2016). Conditional deletion of the prolactin receptor reveals functional subpopulations of dopamine neurons in the arcuate nucleus of the hypothalamus. Journal of Neuroscience, 36(35), 9173-9185. doi: 10.1523/jneurosci.1471-16.2016

Ladyman, S. R., Augustine, R. A., Scherf, E., Phillipps, H. R., Brown, C. H., & Grattan, D. R. (2016). Attenuated hypothalamic responses to α-melanocyte stimulating hormone during pregnancy in the rat. Journal of Physiology, 594(4), 1087-1101. doi: 10.1113/jp271605

Brown, R. S. E., Wyatt, A. K., Herbison, R. E., Knowles, P. J., Ladyman, S. R., Binart, N., … Grattan, D. R. (2016). Prolactin transport into mouse brain is independent of prolactin receptor. FASEB Journal, 30(2), 1002-1010. doi: 10.1096/fj.15-276519

Conference Contribution - Published proceedings: Abstract

Grattan, D. R., McEwen, H., Ladyman, S., & Shepherd, P. (2016). Feeding and GLP-1 receptor activation stabilize β-catenin in specific hypothalamic nuclei in male rats. Proceedings of the Society for Neuroscience 46th Annual Meeting. 731.21/CCC15. SfN. Retrieved from https://www.sfn.org/

Brown, R. S. E., Kokay, I. C., Phillipps, H. R., Gustafson, P. E., Khant Aung, Z., Ladyman, S. R., & Grattan, D. R. (2016). Conditional deletion of prolactin receptor gene reveals remarkable redundancy in feedback regulation of tuberoinfundibular dopamine neurons by prolactin. Endocrine Reviews, 37(2, Suppl.), FRI-504. Retrieved from http://press.endocrine.org/series/endo-meetings

Conference Contribution - Poster Presentation (not in published proceedings)

Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2016, August). Impaired pregnancy-induced changes to glucose homeostasis in mice lacking prolactin receptors in the pancreas. Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Kaplish, M., Ladyman, S. R., & Grattan, D. R. (2016, August). The effect of pregnancy-induced adaptations on glucagon like-peptide-1 receptor activation-induced stabilisation of beta-catenin in hypothalamic neurons in female rats. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.

MacLeod, M. A., Ladyman, S. R., & Grattan, D. R. (2016, August). The effect of prolactin on AgRP neurons in the arcuate nucleus. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.

Carter, K., Rizwan, M., Ladyman, S. R., & Grattan, D. R. (2016, August). Feeding-induced regulation of Wnt/beta catenin signaling in the mouse hypothalamus. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.

Brown, R. S. E., Kokay, I. C., Phillipps, H. R., Yip, S. H., Gustafson, P., Wyatt, A., Larsen, C. M., Knowles, P., Ladyman, S. R., … Grattan, D. R. (2016, August). Conditional deletion of the prolactin receptor reveals functional subpopulations of dopamine neurons in the arcuate nucleus of the hypothalamus. Verbal presentation at the Medical Sciences Congress (MedSci), Nelson, New Zealand.

2014

Journal - Research Article

Ladyman, S., & Woodside, B. (2014). Food restriction during lactation suppresses Kiss1 mRNA expression and kisspeptin-stimulated LH release in rats. Reproduction, 147, 743-751. doi: 10.1530/rep-13-0426

2013

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2013). JAK-STAT and feeding. JAK-STAT, 2(2), e23675. doi: 10.4161/jkst.23675

Phillipps, H. R., Ladyman, S. R., & Grattan, D. R. (2013). Maintained expression of genes associated with metabolism in the ventromedial hypothalamic nucleus despite development of leptin resistance during pregnancy in the rat. Physiological Reports, 1(6), e00162. doi: 10.1002/phy2.162

Conference Contribution - Published proceedings: Abstract

McEwen, H. J. L., Cognard, E., Ladyman, S. R., Shepherd, P. R., & Grattan, D. R. (2013). Regulation of beta-catenin by GLP-1 in the hypothalamus. Endocrine Reviews, 34(3, Suppl.), SAT-825. Retrieved from http://press.endocrine.org/series/endo-meetings

2012

Journal - Research Article

Ladyman, S. R., Fieldwick, D. M., & Grattan, D. R. (2012). Suppression of leptin-induced hypothalamic JAK/STAT signaling and feeding response during pregnancy in the mouse. Reproduction, 144(1), 83-90. doi: 10.1530/rep-12-0112

Conference Contribution - Published proceedings: Abstract

McEwen, H. J. L., Smith, G. C., Ladyman, S. R., Grattan, D. R., & Shepherd, P. R. (2012). Phosphorylation of Akt by antipsychotic drugs is induced indirectly through dysregulation of glucose homeostasis. In B. Leitch & J. Shemmell (Eds.), Proceedings of the 30th International Australasian Winter Conference on Brain Research. 30, (pp. 64). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2012.html

2011

Journal - Research Article

Ladyman, S. R., Sapsford, T. J., & Grattan, D. R. (2011). Loss of acute satiety response to cholecystokinin in pregnant rats. Journal of Neuroendocrinology, 23(11), 1091-1098. doi: 10.1111/j.1365-2826.2011.02191.x

Conference Contribution - Published proceedings: Abstract

McEwen, H. J. L., Ladyman, S. R., Cognard, E., Shepherd, P. R., & Grattan, D. R. (2011). Activation of the Wnt signalling pathway in the hypothalamus by metabolic parameters and its potential: Possible involvement in the glucose homeostasis? In B. Leitch (Ed.), Proceedings of the 29th International Australasian Winter Conference on Brain Research. 29, 5.25. AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/abstracts/abstracts2011.html

Scherf, E., Ladyman, S., & Grattan, D. (2011). Patterns of α-MSH-induces neuronal activation in the pregnant rat brain. New Zealand Medical Journal, 124(1335). Retrieved from http://www.nzma.org.nz/journal/124-1335/4693/content.pdf

Conference Contribution - Verbal presentation and other Conference outputs

Scherf, E. M., Ladyman, S. R., & Grattan, D. R. (2011, August). Patterns of α-MSH-induced neuronal activation in the pregnant rat brain. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Ladyman, S. R., & Grattan, D. R. (2011, August). Pregnancy-induced adaptations in the neuroendocrine networks controlling metabolism. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

2010

Journal - Research Article

Ladyman, S. R., Augustine, R. A., & Grattan, D. R. (2010). Hormone interactions regulating energy balance during pregnancy. Journal of Neuroendocrinology, 22, 805-817. doi: 10.1111/j.1365-2826.2010.02017.x

Conference Contribution - Published proceedings: Abstract

Ladyman, S. R., & Grattan, D. R. (2010). Leptin resistance during pregnancy is associated with a loss of the satiety response to cholecystokinin. Proceedings of the Society for Neuroscience 40th Annual Meeting. SfN. Retrieved from http://www.abstractsonline.com/Plan/SSResults.aspx

Conference Contribution - Poster Presentation (not in published proceedings)

Fieldwick, D. M., Ladyman, S. R., & Grattan, D. R. (2010, November-December). Suppression of leptin induced pSTAT3 in the hypothalamus of pregnant mice. Poster session presented at the Medical Sciences Congress: A New Decade of Discovery (MedSciNZ), Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Ladyman, S. R., & Grattan, D. R. (2010, November-December). Development of hypothalamic insulin resistance during pregnancy. Verbal presentation at the Medical Sciences Congress: A New Decade of Discovery (MedSciNZ), Queenstown, New Zealand.

2009

Journal - Research Article

Ladyman, S. R., & Woodside, B. (2009). Regulation of maternal food intake and mother-pup interactions by the Y5 receptor. Physiology & Behavior, 97, 91-97. doi: 10.1016/j.physbeh.2009.02.008

Ladyman, S. R., Tups, A., Augustine, R. A., Swahn-Azavedo, A., Kokay, I. C., & Grattan, D. R. (2009). Loss of hypothalamic response to leptin during pregnancy associated with development of melanocortin resistance. Journal of Neuroendocrinology, 21(5), 449-456. doi: 10.1111/j.1365-2826.2009.01862.x

2008

Chapter in Book - Research

Woodside, B., Augustine, R. A., Ladyman, S. R., Naef, L., & Grattan, D. R. (2008). Role of prolactin in the metabolic adaptations to pregnancy and lactation. In R. S. Bridges (Ed.), Neurobiology of the parental brain. (pp. 249-267). London: Academic Press.

Journal - Research Article

Augustine, R. A., Ladyman, S. R., & Grattan, D. R. (2008). From feeding one to feeding many: Hormone-induced changes in bodyweight homeostasis during pregnancy (Symposium report). Journal of Physiology, 586(2), 387-397. doi: 10.1113/jphysiol.2007.146316

Journal - Research Other

Ladyman, S. R. (2008). Leptin resistance during pregnancy in the rat. Journal of Neuroendocrinology, 20(269), 269-277. doi: 10.1111/j.1365-2826.2007.01628.x

2007

Journal - Research Article

Grattan, D. R., Ladyman, S. R., & Augustine, R. A. (2007). Hormonal induction of leptin resistance during pregnancy. Physiology & Behavior, 91, 366-374.

2006

Conference Contribution - Published proceedings: Abstract

Augustine, R. A., Ladyman, S. R., Swahn Azavedo, A. M., Kokay, I. C., & Grattan, D. R. (2006). Pregnancy-induced leptin resistance involves a loss of appetite suppression by alpha-melanocyte stimulating hormone. Endocrine Journal. 53(Suppl.), (pp. 100). [Abstract]

2005

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2005). Suppression of leptin receptor messenger ribonucleic acid and leptin responsiveness in the ventromedial nucleus of the hypothalamus during pregnancy in the rat. Endocrinology, 146(9), 3868-3874.

2004

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2004). Region-specific reduction in leptin-induced phosphorylation of signal transducer and activator of transcription-3 (STAT3) in the rat hypothalamus is associated with leptin resistance during pregnancy. Endocrinology, 145(8), 3704-3711.

Conference Contribution - Published proceedings: Abstract

Ladyman, S. R., & Grattan, D. R. (2004). Leptin-induced phosphorylation of STAT3 in alpha-MSH neurons is maintained during pregnancy in the rat. Proceedings of the Society for Neuroscience Abstracts. (893.21). Retrieved from http://sfn.scholarone.com/itin2004/index.html

2003

Journal - Research Article

Augustine, R. A., Kokay, I. C., Andrews, Z. B., Ladyman, S. R., & Grattan, D. R. (2003). Quantitation of prolactin receptor mRNA in the maternal rat brain during pregnancy and lactation. Journal of Molecular Endocrinology, 31, 221-232.

Todd, B. J., Ladyman, S. R., & Grattan, D. R. (2003). Suppression of pulsatile luteinizing hormone secretion but not luteinizing hormone surge in leptin resistant obese Zucker rats. Journal of Neuroendocrinology, 15, 61-68.

Conference Contribution - Published proceedings: Abstract

Ladyman, S. R., & Grattan, D. R. (2003). Exogenous leptin does not suppress appetite in pregnant rats. Proceedings of the 33rd Annual Meeting of the Society for Neuroscience. Washington, DC: Society for Neuroscience. Retrieved from http://sfn.scholarone.com/itin2003

Ladyman, S. R., & Grattan, D. R. (2003). Effect of intracerebroventricular leptin administration on food intake in pregnant and cycling rats. Proceedings of the Endocrine Society of Australia. 46(185), (pp. 203-204). [Abstract]

2000

Conference Contribution - Published proceedings: Abstract

Todd, B. J., Ladyman, S. R., Davis, G., & Grattan, D. R. (2000). Characterisation of luteinising hormone secretion in the female obese Zucker rat. Proceedings of the University of Otago Medical School. 78, (pp. 29). [Abstract]