Accessibility Skip to Global Navigation Skip to Local Navigation Skip to Content Skip to Search Skip to Site Map Menu

Lara Friedlander

Lara Friedlander is a new and emerging researcher and member of the Immunopathology Research Group of the Sir John Walsh Research Institute. She has developed research themes in pulpal biology, regeneration and angiogenesis; and separate from this is also active in research related to Endodontic curriculum development and teaching.

Results of her PhD research around pulp biology and angiogenesis associated with immature permanent teeth have been presented at international conferences and publication in internationally peer reviewed journals. This work has influenced clinical practice by providing further knowledge about pulp cell behaviour and healing following dental trauma.

As main author she has published on Endodontic teaching and this work is on-going and now looking at five year outcomes.

Lara was invited to Switzerland to speak on endodontic curriculum development at the University Forum of 160 international universities.

Lara is a co-supervisor of Clinical Doctorate students and has had substantial competitive grant applications associated with these. This includes angiogenesis associated with oral pathology and broader clinical research pertaining to endodontic practice and disease. From this work, three manuscripts have been published in internationally peer reviewed journals and oral presentations made at international conferences.

As part of the Immunopathology group Lara assists in advising on projects including PhD pulp research which has evolved from her own research theme.

Contact details

Tel 64 3 479 7126
Email lara.friedlander@otago.ac.nz

^ Top of page

Publications

Arora, S., Cooper, P. R., Friedlander, L. T., Seo, B., Rizwan, S. B., Rich, A. M., & Hussaini, H. M. (2022). Potentiality and inflammatory marker expression are maintained in dental pulp cell cultures from carious teeth. International Journal of Molecular Sciences, 23(16), 9425. doi: 10.3390/ijms23169425

AlSamahi, S., Milne, T. M., Hussaini, H., Rich, A. M., & Friedlander, L. T. (2022). Type 2 diabetes and the clinically normal pulp: An in-vitro study. International Endodontic Journal. Advance online publication. doi: 10.1111/iej.13732

Arora, S., Cooper, P. R., Ratnayake, J. T., Friedlander, L. T., Rizwan, S. B., Seo, B., & Hussaini, H. M. (2022). A critical review of in vitro research methodologies used to study mineralization in human dental pulp cell cultures. International Endodontic Journal, 55(Suppl. 1), 3-13. doi: 10.1111/iej.13684

Chutipongpisit, K., Parachuru, V. P., Friedlander, L. T., Hussaini, H. M., & Rich, A. M. (2021). Immunohistochemical and immunofluorescence expression profile of lymphatic endothelial cell markers in oral cancer. International Journal of Experimental Pathology, 102, 268-278. doi: 10.1111/iep.12411

Arora, S., Cooper, P. R., Friedlander, L. T., Rizwan, S., Seo, B., Rich, A. M., & Hussaini, H. M. (2021). Potential application of immunotherapy for modulation of pulp inflammation: Opportunities for vital pulp treatment. International Endodontic Journal, 54, 1263-1274. doi: 10.1111/iej.13524

AlSamahi, S., Milne, T. M., Hussaini, H., Rich, A. M., & Friedlander, L. T. (2022). Type 2 diabetes and the clinically normal pulp: An in-vitro study. International Endodontic Journal. Advance online publication. doi: 10.1111/iej.13732

Journal - Research Article

Arora, S., Cooper, P. R., Friedlander, L. T., Seo, B., Rizwan, S. B., Rich, A. M., & Hussaini, H. M. (2022). Potentiality and inflammatory marker expression are maintained in dental pulp cell cultures from carious teeth. International Journal of Molecular Sciences, 23(16), 9425. doi: 10.3390/ijms23169425

Journal - Research Article

Chutipongpisit, K., Parachuru, V. P., Friedlander, L. T., Hussaini, H. M., & Rich, A. M. (2021). Immunohistochemical and immunofluorescence expression profile of lymphatic endothelial cell markers in oral cancer. International Journal of Experimental Pathology, 102, 268-278. doi: 10.1111/iep.12411

Journal - Research Article

Al-Hassiny, A., Hussani, H., Milne, T., Seo, B., Rich, A. M., & Friedlander, L. T. (2019). Vascularity and angiogenic signaling in the dentine-pulp complex of immature and mature permanent teeth. European Endodontic Journal, 4(2), 80-85. doi: 10.14744/eej.2019.26349

Journal - Research Article

Friedlander, L. T., Meldrum, A. M., & Lyons, K. (2019). Curriculum development in final year dentistry to enhance competency and professionalism for contemporary general dental practice. European Journal of Dental Education, 23, 489-506. doi: 10.1111/eje.12458

Journal - Research Article

Al-Hassiny, A., Friedlander, L. T., Parachuru, V. P. B., Seo, B., Hussaini, H. M., & Rich, A. M. (2018). Upregulation of angiogenesis in oral lichen planus. Journal of Oral Pathology & Medicine, 47(2), 173-178. doi: 10.1111/jop.12665

Journal - Research Article

Friedlander, L. T., Coates, D., Seymour, G., Cullinan, M., & Rich, A. M. (2018). Vascularity and VEGF/VEGFR2 signaling in the dentine–pulp complex of immature and mature permanent teeth. European Endodontic Journal, 3(3), 153-159. doi: 10.14744/eej.2018.07269

Journal - Research Article

Russell, A. A., Chandler, N. P., & Friedlander, L. T. (2018). Crack formation following root-end preparation in roots with the butterfly effect. European Endodontic Journal, 3(2), 107-112. doi: 10.14744/eej.2018.47965

Journal - Research Article

Russell, A., Friedlander, L., & Chandler, N. (2018). Sealer penetration and adaptation in root canals with the butterfly effect. Australian Endodontic Journal, 44(3), 225-234. doi: 10.1111/aej.12238

Journal - Research Article

Russell, A. A., Chandler, N. P., & Friedlander, L. T. (2017). Vertical root fractures in root canal-treated teeth. ENDO, 11(3), 173-182.

Journal - Research Article

Firth, F. A., Friedlander, L. T., Parachuru, V. P. B., Kardos, T. B., Seymour, G. J., & Rich, A. M. (2015). Regulation of immune cells in oral lichen planus. Archives of Dermatological Research, 307, 333-339. doi: 10.1007/s00403-015-1540-8

Journal - Research Article

Friedlander, L. T., Hussaini, H., Cullinan, M. P., Seymour, G. J., De Silva, R. K., De Silva, H., Cameron, C., & Rich, A. M. (2015). VEGF and VEGFR2 in dentigerous cysts associated with impacted third molars. Pathology, 47(5), 446-451. doi: 10.1097/pat.0000000000000272

Journal - Research Article

Friedlander, L., McElroy, K., Daniel, B., Cullinan, M., & Hanlin, S. (2015). Direct pulp capping of permanent teeth in New Zealand general dental practice: A practice based research study. New Zealand Dental Journal, 111(2), 58-64.

Journal - Research Article

Alothmani, O. S., Chandler, N. P., & Friedlander, L. T. (2013). The anatomy of the root apex: A review and clinical considerations in endodontics. Saudi Endodontic Journal, 3(1), 1-9. doi: 10.4103/1658-5984.116273

Journal - Research Article

Alothmani, O. S., Friedlander, L. T., & Chandler, N. P. (2013). Radiographic assessment of endodontic working length. Saudi Endodontic Journal, 3(2), 57-64. doi: 10.4103/1658-5984.118145

Journal - Research Article

Alothmani, O. S., Friedlander, L. T., Monteith, B. D., & Chandler, N. P. (2013). Influence of clinical experience on the radiographic determination of endodontic working length. International Endodontic Journal, 46(3), 211-216. doi: 10.1111/j.1365-2591.2012.02109.x

Journal - Research Article

Lin, Y. P., Love, R. M., Friedlander, L. T., Shang, H. F., & Pai, M. H. (2013). Expression of Toll-like receptor 2 and 4, and the OPG-RANKL-RANK system in inflammatory external root resorption and external cervical resorption. International Endodontic Journal, 46, 971-981. doi: 10.1111/iej.12088

Journal - Research Article

Friedlander, L., & Anderson, V. (2011). A new predoctoral endodontic module: Evaluating learning and effectiveness. Journal of Dental Education, 75(3), 351-359.

Journal - Research Article

Friedlander, L. T., Love, R. M., & Cullinan, M. P. (2009). Dental stem cells and their potential role in apexogenesis and apexification. International Endodontic Journal, 42(11), 955-962. doi: 10.1111/j.1365-2591.2009.01622.x

Journal - Research Article

Buchanan, J., Colquhoun, A., Friedlander, L., Evans, S., Whitley, B., & Thomson, M. (2005). Maxillofacial fractures at Waikato Hospital, New Zealand: 1989 to 2000. New Zealand Medical Journal, 118(1217). Retrieved from http://journal.nzma.org.nz/journal/118-1217/1529/content.pdf

Journal - Research Article

Friedlander, L. T., Love, R. M., & Chandler, N. P. (2002). A comparision of phosphor-plate digital images with conventional radiographs for the perceived clarity of fine endodontic files and periapical lesions. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontology, 93, 321-327.

Journal - Research Article

Arora, S., Cooper, P. R., Ratnayake, J. T., Friedlander, L. T., Rizwan, S. B., Seo, B., & Hussaini, H. M. (2022). A critical review of in vitro research methodologies used to study mineralization in human dental pulp cell cultures. International Endodontic Journal, 55(Suppl. 1), 3-13. doi: 10.1111/iej.13684

Journal - Research Other

Arora, S., Cooper, P. R., Friedlander, L. T., Rizwan, S., Seo, B., Rich, A. M., & Hussaini, H. M. (2021). Potential application of immunotherapy for modulation of pulp inflammation: Opportunities for vital pulp treatment. International Endodontic Journal, 54, 1263-1274. doi: 10.1111/iej.13524

Journal - Research Other

Sadr, A., Rossi-Fedele, G., Love, R. M., George, R., Parashos, P., Wu, M. C.-Y., Friedlander, L., … Abbott, P. V. (2021). Revised guidelines for the endodontic education of dentistry students in Australia and New Zealand (FEBRUARY 2021). Australian Endodontic Journal. Advance online publication. doi: 10.1111/aej.12501

Journal - Research Other

Coates, D. E., Alansary, M., Friedlander, L., Zanicotti, D. G., & Duncan, W. J. (2020). Dental pulp stem cells in serum-free medium for regenerative medicine. Journal of the Royal Society of New Zealand, 50(1), 80-90. doi: 10.1080/03036758.2019.1673447

Journal - Research Other

Rossi-Fedele, G., Damiani, F., Love, R. M., George, R., Parashos, P., Wu, M. C.-Y., Friedlander, L., … Abbott, P. V. (2020). Revised guidelines for educational requirements for specialisation in endodontics in Australia and New Zealand (July 2020). Australian Endodontic Journal, 46, 302-306. doi: 10.1111/aej.12431

Journal - Research Other

Friedlander, L. T., Chandler, N. P., & Drummond, B. K. (2013). Avulsion and replantation of a primary incisor tooth. Dental Traumatology, 29(6), 494-497. doi: 10.1111/j.1600-9657.2012.01168.x

Journal - Research Other

Friedlander, L., Chandler, N., & Love, R. (2011). Periapical healing following combined non-surgical and surgical retreatments [Case report]. ENDO, 5(1), 27-34.

Journal - Research Other

Friedlander, L. (2013). [Review of the book Seltzer and Bender's dental pulp]. New Zealand Dental Journal, 109(1), 32. [Book Review].

Journal - Professional & Other Non-Research Articles

AlSamahi, S., Milne, T. J., Rich, A. M., Hussaini, H. M., & Friedlander, L. T. (2019). The influences of Type 2 diabetes on clinically normal dental pulp tissues. International Endodontic Journal, 52(Suppl. 1), (pp. 39). doi: 10.1111/iej.13172

Conference Contribution - Published proceedings: Abstract

Al Samahi, S., Milne, T., Hussaini, H., Rich, A., & Friedlander, L. (2018). Increased expression of advanced glycation end-products (AGE) and its receptor (RAGE) in normal dental pulp of Type 2 diabetics. New Zealand Dental Journal, 114(4), (pp. 187). [Abstract]

Conference Contribution - Published proceedings: Abstract

Chandler, N., Russell, A., & Friedlander, L. T. (2017). The butterfly effect: An investigation of sealer penetration and adaptation in root canals. Journal of Dental Research, 96(Spec. Iss. B), 2810184. [Abstract]

Conference Contribution - Published proceedings: Abstract

Navani, H. A., Hussaini, H. M., Milne, T. J., Rich, A. M., & Friedlander, L. T. (2017). Angiopoietins and Tie2 receptor expression in immature permanent teeth. International Endodontic Journal, 50(Suppl. 1), (pp. 53). doi: 10.1111/iej.12813

Conference Contribution - Published proceedings: Abstract

Navani, H., Hussaini, H. M., Milne, T. J., Rich, A. M., & Friedlander, L. T. (2017). Angiogenic growth factor expression in the apical papilla of immature permanent teeth. New Zealand Dental Journal, 113(4), (pp. 53). [Abstract]

Conference Contribution - Published proceedings: Abstract

Russell, A. A., Chandler, N. P., & Friedlander, L. T. (2017). Crack formation following root-end preparations in roots with the butterfly effect. International Endodontic Journal, 50(Suppl. 1), (pp. 38-39). doi: 10.1111/iej.12813

Conference Contribution - Published proceedings: Abstract

Russell, A. A., Chandler, N. P., & Friedlander, L. T. (2017). The butterfly effect: An investigation of sealer penetration an adaptation in root canals. New Zealand Dental Journal, 113(4), (pp. 60). [Abstract]

Conference Contribution - Published proceedings: Abstract

Alansary, M., Drummond, B., Friedlander, L., Seymour, G. J., Cullinan, M. P., & Coates, D. E. (2016). Primary teeth pulp cells, not only MSCs, but a population with a unique “stem cell” signature. Proceedings of the Sir John Walsh Research Institute Research Symposium. (pp. 8-9). Retrieved from http://www.otago.ac.nz/sjwri/news/otago621026

Conference Contribution - Published proceedings: Abstract

Chutipongpisit, K., Parachuru, V. P., Hussaini, H. M., Friedlander, L. T., & Rich, A. M. (2016). Lymphangiogenic factors in oral cancer. Proceedings of the Sir John Walsh Research Institute Research Symposium. (pp. 22). Retrieved from http://www.otago.ac.nz/sjwri/news/otago621026

Conference Contribution - Published proceedings: Abstract

Friedlander, L. T., Chandler, N. P., & Daniel, B. (2016). Five year analysis of undergraduate education using tapered hand and rotary endodontic instrumentation techniques. International Endodontic Journal, 49(1), (pp. 85). doi: 10.1111/iej.12496

Conference Contribution - Published proceedings: Abstract

Alansary, M., Coates, D. E., Seymour, G., Cullinan, M. P., Friedlander, L. T., & Drummond, B. (2015). Primary tooth pulp progenitor cells' characterisation and differentiation potential. Journal of Dental Research, 94(Spec Iss B), 2332761. Retrieved from http://www.iadr.org/

Conference Contribution - Published proceedings: Abstract

Allsobrook, O., Parachuru, V., Milne, T., Friedlander, L., Seymour, G., & Rich, A. (2015). Angiogenic factors in oral squamous cell carcinoma. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 119(3), (pp. e140). doi: 10.1016/j.oooo.2014.07.163

Conference Contribution - Published proceedings: Abstract

Friedlander, L. T., Ong, J., Hanlin, S. M., & Daniel, B. (2015). Vital Pulp Therapy: When, how, why? A NZ PBRN study. Journal of Dental Research, 94(Spec Iss B), 2334433. Retrieved from http://www.iadr.org/

Conference Contribution - Published proceedings: Abstract

Hanlin, S. M., Chow, C., Dalzell, O., Friedlander, L. T., & Daniel, B. (2015). The understanding of Vital Pulp Therapy in a dental faculty. Journal of Dental Research, 94(Spec Iss B), 2335048. Retrieved from http://www.iadr.org/

Conference Contribution - Published proceedings: Abstract

Friedlander, L. T., Rich, A. M., Cullinan, M. P., De Silva, H., De Silva, G. R., & Seymour, G. J. (2014). Spatial localization of angiogenic growth factors and receptors in immature permanent teeth. International Endodontic Journal, 47(1), (pp. -96). doi: 10.1111/iej.12212

Conference Contribution - Published proceedings: Abstract

Firth, F. A., Friedlander, L. T., Parachuru, V. P., Kardos, T. B., Rich, A. M., & Seymour, G. J. (2013). Regulation of immune cells in oral lichen planus. Journal of Dental Research, 92(Spec Iss A), 2274. Retrieved from http://www.dentalresearch.org

Conference Contribution - Published proceedings: Abstract

Friedlander, L. (2013). The use of contemporary endodontic techniques to improve patient outcomes. Proceedings of the Sir John Walsh Research Institute (SJWRI) Clinical Research Programme Symposium: When Practice Meets Research: A Future Full of Possibilities. Retrieved from http://sjwri.otago.ac.nz/research/pbrn/

Conference Contribution - Published proceedings: Abstract

Chandler, N., Kim, Y. A., Herbison, G. P., Hauman, C. H., & Friedlander, L. T. (2012). Crack formation during apicectomy: Operating microscope observations and SEM images. Journal of Dental Research, 91(Spec Iss C), 169312. Retrieved from http://www.dentalresearch.org

Conference Contribution - Published proceedings: Abstract

Firth, F. A., Friedlander, L. T., Parachuru, P., Kardos, T. B., Rich, A. M., & Seymour, G. J. (2012). Immunoregulatory cells in oral lichen planus. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 114(4), (pp. e40). doi: 10.1016/j.oooo.2012.07.477

Conference Contribution - Published proceedings: Abstract

Firth, F. A., Friedlander, L., Parachuru, V., Kardos, T., Rich, A., & Seymour, G. (2012). Regulation of immune cells in oral lichen planus. Journal of Dental Research, 91(Spec Iss C), 169862. Retrieved from http://www.dentalresearch.org

Conference Contribution - Published proceedings: Abstract

Kim, A. Y. J., Friedlander, L., Herbison, P., Hauman, C., & Chandler, N. P. (2012). The resected root-end: Is what you see, what you get? A naked eye, optical and SEM study. Journal of Endodontics, 38(3), OR 25, (pp. e19). [Abstract]

Conference Contribution - Published proceedings: Abstract

More publications...