Associate Professor Jo Kirman

2023

Journal - Professional & Other Non-Research Articles

Kirman, J. R., Weinkove, R., & Borger, J. G. (2023). Immunology across two islands: Understanding the research landscape of Aotearoa (New Zealand) [Interview]. Immunology & Cell Biology. Advance online publication. doi: 10.1111/imcb.12709

2022

Conference Contribution - Poster Presentation (not in published proceedings)

Sircombe, K. J., Kirman, J. R., & Pletzer, D. (2022, August). Can BCG vaccination train innate immune cells to protect against skin and soft tissue infections? Poster session presented at the Webster Centre for Infectious Diseases Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Ryder, B., Foster, M., Krotky, N., Daniels, N., & Kirman, J. (2022, August). Teaching the unteachable: Training innate immune cells in the lung using the BCG vaccine. Verbal presentation at the Webster Centre for Infectious Diseases Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

2021

Journal - Research Article

Chen, S., Quan, D. H., Wang, X. T., Sandford, S., Kirman, J. R., Britton, W. J., & Rehm, B. H. A. (2021). Particulate mycobacterial vaccines induce protective immunity against tuberculosis in mice. Nanomaterials, 11, 2060. doi: 10.3390/nano11082060

Blanchett, S., Tsai, C. J. Y., Sandford, S., Loh, J. M. S., Huang, L., Kirman, J. R., & Proft, T. (2021). Intranasal immunisation with Ag85B peptide 25 displayed on Lactococcus lactis using the PilVax platform induces antigen-specific B- and T-cell responses. Immunology & Cell Biology, 99, 767-781. doi: 10.1111/imcb.12462

2020

Journal - Research Other

Borger, J. G., Le Gros, G., & Kirman, J. R. (2020). The role of innate lymphoid cells in mucosal immunity. Frontiers in Immunology, 11, 1233. doi: 10.3389/fimmu.2020.01233

2019

Journal - Research Article

Lamichhane, R., Schneider, M., de la Harpe, S. M., Harrop, T. W. R., Hannaway, R. F., Dearden, P. K., Kirman, J. R., Tyndall, J. D. A., Vernall, A. J., & Ussher, J. E. (2019). TCR- or cytokine-activated CD8⁺ mucosal-associated invariant T cells are rapid polyfunctional effectors that can coordinate immune responses. Cell Reports, 28(12), 3061-3076.e5. doi: 10.1016/j.celrep.2019.08.054

Chen, S., Sandford, S., Kirman, J. R., & Rehm, B. H. A. (2019). Innovative antigen carrier system for the development of tuberculosis vaccines. FASEB Journal, 33, 7505-7518. doi: 10.1096/fj.201802501RR

Ryder, B. M., Sandford, S. K., Manners, K. M., Dalton, J. P., Wiles, S., & Kirman, J. R. (2019). Gr1^int/high cells dominate the early phagocyte response to mycobacterial lung infection in mice. Frontiers in Microbiology, 10, 402. doi: 10.3389/fmicb.2019.00402

Journal - Research Other

Kirman, J. R., Quinn, K. M., & Seder, R. A. (2019). Immunological memory. Immunology & Cell Biology, 97, 615-616. doi: 10.1111/imcb.12280

Steigler, P., Verrall, A. J., & Kirman, J. R. (2019). Beyond memory T cells: Mechanisms of protective immunity to tuberculosis infection. Immunology & Cell Biology, 97, 647-655. doi: 10.1111/imcb.12278

2018

Journal - Research Article

Chen, S., Sandford, S., Kirman, J., & Rehm, B. H. A. (2018). Design of bacterial inclusion bodies as antigen carrier systems. Advanced Biosystems, 2(11), 1800118. doi: 10.1002/adbi.201800118

Prendergast, K. A., Daniels, N. J., Petersen, T. R., Hermans, I. F., & Kirman, J. R. (2018). Langerin⁺ CD8α⁺ dendritic cells drive early CD8⁺ T cell activation and IL-12 production during systemic bacterial infection. Frontiers in Immunology, 9, 953. doi: 10.3389/fimmu.2018.00953

Steigler, P., Daniels, N. J., McCulloch, T. R., Ryder, B. M., Sandford, S. K., & Kirman, J. R. (2018). BCG vaccination drives accumulation and effector function of innate lymphoid cells in murine lungs. Immunology & Cell Biology, 96(4), 379-389. doi: 10.1111/imcb.12007

Conference Contribution - Poster Presentation (not in published proceedings)

Ryder, B., Wiles, S., & Kirman, J. (2018, September). BCG immunisation alters lung phagocyte dynamics during early mycobacterial infection of mice. Poster session presented at the Otago Spotlight Symposium on Infectious Disease, Wellington, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Lamichhane, R., de la Harpe, S., Harrop, T., Vernall, A., Tyndall, J., Dearden, P., Kirman, J., & Ussher, J. E. (2018, August). Differential regulation of MR1- and cytokine stimulated MAIT cells. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Blanchett, S., Loh, J., Kirman, J., & Proft, T. (2018, August). PilVax: A novel peptide carrier for the development of vaccines against tuberculosis. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Ryder, B. M., Steigler, P., Wiles, S., & Kirman, J. R. (2018, August). BCG vaccination induces ILC expansion and alters phagocyte dynamics early after mycobacterial challenge. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Kirman, J. (2018, August). Progress towards development of an improved TB vaccine. Verbal presentation at the Australasian Tuberculosis Conference, Wellington, New Zealand.

Kirman, J. (2018, September). Deciphering the protective immune response to tuberculosis. Verbal presentation at the Otago Spotlight Symposium on Infectious Disease, Wellington, New Zealand.

2017

Conference Contribution - Published proceedings: Abstract

Ryder, B., Steigler, P., Lewis, C., & Kirman, J. (2017). Innate lymphoid cell response to vaccination against tuberculosis in mice. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 80). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html

Lamichhane, R., Kirman, J., & Ussher, J. (2017). Differences in the effector functions of MR1- and cytokine stimulated MAIT cells. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 47-48). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html

Conference Contribution - Poster Presentation (not in published proceedings)

Lamichhane, R., de la Harpe, S., Harrop, T., Vernall, A., Tyndall, J., Dearden, P., Kirman, J., & Ussher, J. (2017, November). Differences in the effector function of MR1- and cytokine stimulated MAIT cells. Poster session presented at the 10th International CD1-MR1 Workshop, Napa, USA.

Conference Contribution - Verbal presentation and other Conference outputs

Ryder, B., Steigler, P., Lewis, C., & Kirman, J. R. (2017, November-December). Innate lymphoid cell response to BCG vaccination in mice. Verbal presentation at the Proceedings of the 46th Australasian Society for Immunology (ASI) Annual Scientific Meeting, Brisbane, Australia.

Ryder, B., Steigler, P., Lewis, C., & Kirman, J. (2017, July). Innate lymphoid cell response to BCG vaccination in mice. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

Lamichhane, R., Kirman, J., & Ussher, J. E. (2017, July). Differences in the effector functions of MR1- and Cytokine stimulated MAIT cells. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

2016

Journal - Research Article

Kirman, J. R., Henao-Tamayo, M. I., & Agger, E. M. (2016). The memory immune response to tuberculosis. Microbiology Spectrum, 4(6), TBTB2-0009-2016. doi: 10.1128/microbiolspec.TBTB2-0009-2016

Conference Contribution - Published proceedings: Abstract

Steigler, P., & Kirman, J. (2016). Memory CD4 and CD8 T cells are dispensable for BCG-vaccine mediated protection. European Journal of Immunology, 46(Suppl. 1), (pp. 640). doi: 10.1002/eji.201670200

Ryder, B. M., Manners, K., & Kirman, J. R. (2016). Dynamics of phagocytic cells early after mycobacterial lung infection. European Journal of Immunology, 46(Suppl. 1), (pp. 513-514). doi: 10.1002/eji.201670200

Steigler, P., McCulloch, T., & Kirman, J. R. (2016). Mucosal BCG vaccination promotes function and accumulation of innate lymphoid cells in murine lungs. European Journal of Immunology, 46(Suppl. 1), (pp. 146). doi: 10.1002/eji.201670200

Prendergast, K., Petersen, T., Hermans, I., & Kirman, J. (2016). Langerin⁺ CD8a⁺ dendritic cells play a protective role early after systemic bacterial infection in mice. European Journal of Immunology, 46(Suppl. 1), (pp. 104-105). doi: 10.1002/eji.201670200

2015

Journal - Research Article

Kuhn, S., Yang, J., Hyde, E. J., Harper, J. L., Kirman, J. R., & Ronchese, F. (2015). IL-1βR-dependent priming of antitumor CD4⁺ T cells and sustained antitumor immunity after peri-tumoral treatment with MSU and mycobacteria. OncoImmunology, 4(10), e1042199. doi: 10.1080/2162402X.2015.1042199

Conference Contribution - Verbal presentation and other Conference outputs

Kirman, J. (2015, July). Innate lymphoid cell (ILC) distribution and function after BCG vaccination of mice. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Auckland, New Zealand.

2014

Journal - Research Article

Prendergast, K. A., Osmond, T. L., Ochiai, S., Hermans, I. F., & Kirman, J. R. (2014). Sustained in vivo depletion of splenic langerin⁺ CD8α⁺ dendritic cells is well-tolerated by lang-DTREGFP mice. Journal of Immunological Methods, 406, 104-109. doi: 10.1016/j.jim.2014.02.005

2013

Journal - Research Article

Bassett, I. M., Lun, S., Bishai, W. R., Guo, H., Kirman, J. R., Altaf, M., & O'Toole, R. F. (2013). Detection of inhibitors of phenotypically drug-tolerant Mycobacterium tuberculosis using an in vitro bactericidal screen. Journal of Microbiology, 51(5), 651-658. doi: 10.1007/s12275-013-3099-4

Kuhn, S., Hyde, E. J., Yang, J., Rich, F. J., Harper, J. L., Kirman, J. R., & Ronchese, F. (2013). Increased numbers of monocyte-derived dendritic cells during successful tumor immunotherapy with immune-activating agents. Journal of Immunology, 191(4), 1984-1992. doi: 10.4049/jimmunol.1301135

Conference Contribution - Published proceedings: Abstract

Steigler, P., Ancelet, L. R., Petersen, T. R., & Kirman, J. R. (2013). Novel adoptive transfer model to identify protective memory CD4⁺T cell subsets in mycobacterial infection. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 178-179). Retrieved from http://www.asi2013.org/

Kuhn, S., Hyde, E. J., Yang, J., Rich, F. J., Harper, J. L., Kirman, J. R., & Ronchese, F. (2013). Successful reprogramming of the tumour microenvironment with immune-activating agents elicits inflammatory DC and activates innate and adaptive effectors. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 91). Retrieved from http://www.asi2013.org/

Al Barwani, F., Young, S., Baird, M., Kirman, J., Larsen, D., & Ward, V. (2013). The sweetening of VLP. Proceedings of 15th Conference on Formulation and Delivery of Bioactives: Found in Translation. Retrieved from http://bioactives.otago.ac.nz/

2012

Journal - Research Article

Ancelet, L., & Kirman, J. (2012). Shaping the CD4⁺ memory immune response against tuberculosis: The role of antigen persistence, location and multi-functionality. Biomolecular Concepts, 3(1), 13-20. doi: 10.1515/BMC.2011.051

Rich, F. J., Kuhn, S., Hyde, E. J., Harper, J. L., Ronchese, F., & Kirman, J. R. (2012). Induction of T cell responses and recruitment of an inflammatory dendritic cell subset following tumor immunotherapy with Mycobacterium smegmatis. Cancer Immunology, Immunotherapy, 61(12), 2333-2342. doi: 10.1007/s00262-012-1291-8

Prendergast, K. A., & Kirman, J. R. (2012). Dendritic cell subsets in mycobacterial infection: Control of bacterial growth and T cell responses. Tuberculosis, 93(2), 115-122. doi: 10.1016/j.tube.2012.10.008

Ancelet, L. R., Aldwell, F. E., Rich, F. J., & Kirman, J. R. (2012). Oral vaccination with lipid-formulated BCG induces a long-lived, multifunctional CD4⁺ T cell memory immune response. PLoS ONE, 7(9), e45888. doi: 10.1371/journal.pone.0045888

Ancelet, L., Rich, F. J., Delahunt, B., & Kirman, J. R. (2012). Dissecting memory T cell responses to TB: Concerns using adoptive transfer into immunodeficient mice. Tuberculosis, 92(5), 422-433. doi: 10.1016/j.tube.2012.05.008

2010

Journal - Research Article

Connor, L. M., Harvie, M. C., Rich, F. J., Quinn, K. M., Brinkmann, V., Le Gros, G., & Kirman, J. R. (2010). A key role for lung-resident memory lymphocytes in protective immune responses after BCG vaccination. European Journal of Immunology, 40, 2482-2492. doi: 10.1002/eji.200940279

Chandrahasen, C., Grimwood, K., Redshaw, N., Rich, F. J., Wood, C., Stanley, J., Kirman, J. R., on behalf of the New Zealand Rotavirus Study Group. (2010). Geographical differences in the proportion of human group A rotavirus strains within New Zealand during one epidemic season. Journal of Medical Virology, 82(5), 897-902. doi: 10.1002/jmv.21739

2008

Journal - Research Article

Grimwood, K., Cohet, C., Rich, F. J., Cheng, S., Wood, C., Redshaw, N., … Kirman, J. R. (2008). Risk factors for respiratory syncytial virus bronchiolitis hospital admission in New Zealand. Epidemiology & Infection, 136(10), 1333-1341. doi: 10.1017/S0950268807000180

Quinn, K. M., Rich, F., Goldsack, L. M., de Lisle, G. W., Buddle, B. M., Delahunt, B., & Kirman, J. R. (2008). Accelerating the secondary immune response by inactivating CD4⁺CD25⁺ T regulatory cells prior to BCG vaccination does not enhance protection against tuberculosis. European Journal of Immunology, 38(3), 695-705.

Conference Contribution - Published proceedings: Abstract

Chandrahasen, C., Redshaw, N., Grimwood, K., Wood, C., Rich, F., & Kirman, J. (2008). Shifting strains: the changing face of rotavirus in New Zealand. Proceedings of the New Zealand Microbiological Society Microbiology Conference. (pp. 22-23). NZMS. Retrieved from http://www.nzmsconference08.org.nz/files/Oral-Abstracts-NZMS-2008.pdf

2007

Journal - Research Article

Goldsack, L., & Kirman, J. R. (2007). Half-truths and selective memory: Interferon gamma, CD4⁺ T cells and protective memory against tuberculosis. Tuberculosis, 87, 465-473. doi: 10.1016/j.tube.2007.07.001

Journal - Research Other

Redshaw, N., Wood, C., Rich, F., Grimwood, K., & Kirman, J. R. (2007). Human bocavirus in infants, New Zealand [Letter to the editor]. Emerging Infectious Diseases, 13(11), 1797-1799.

2006

Journal - Research Article

Matheson, J. W., Rich, F. J., Cohet, C., Grimwood, K., Huang, Q. S., Penny, D., Hendy, M. D., & Kirman, J. R. (2006). Distinct patterns of evolution between respiratory syncytial virus subgroups A and B from New Zealand isolates collected over thirty-seven years. Journal of Medical Virology, 78(10), 1354-1364. doi: 10.1002/jmv.20702

Quinn, K. M., McHugh, R. S., Rich, F. J., Goldsack, L. M., de Lisle, G. W., Buddle, B. M., Delahunt, B., & Kirman, J. R. (2006). Inactivation of CD4⁺CD25⁺ regulatory T cells during early mycobacterial infection increases cytokine production but does not affect pathogen load. Immunology & Cell Biology, 84, 467-474.

2005

Conference Contribution - Published proceedings: Abstract

Grimwood, K., Cohet, C., Rich, F., Huang, Q. S., Matheson, J., Penny, D., & Kirman, J. (2005). Molecular evolution of respiratory syncytial viruses in New Zealand. Respirology, 10(Suppl. 1), (pp. A20). doi: 10.1111/j.1440-1843.2005.00663.x-i1

2004

Conference Contribution - Published proceedings: Abstract

Grimwood, K., Cohet, C., Matheson, J., Rich, F., Huang, Q., Penny, D., & Kirman, J. (2004). Molecular evolution of respiratory syncytial viruses in New Zealand. Canadian Journal of Infectious Diseases. 15(2), (pp. 119). [Abstract]

2000

Journal - Research Article

Kirman, J., Zakaria, Z., McCoy, K., Delahunt, B., & Le Gros, G. (2000). Role of eosinophils in the pathogenesis of Mycobacterium bovis BCG infection in gamma interferon receptor-deficient mice. Infection & Immunity, 68(5), 2976-2978. doi: 10.1128/IAI.68.5.2976-2978.2000

1999

Journal - Research Article

Erb, K. J., Hou, S., Hyland, L., Kirman, J., Moll, H., & Le Gros, G. (1999). Constitutive expression of interleukin 4 in vivo does not lead to the development of T helper 2 type CD8⁺ T cells secreting interleukin 4 or interleukin 5. Immunology Letters, 68(2-3), 383-390. doi: 10.1016/S0165-2478(99)00088-7

Erb, K. J., Kirman, J., Delahunt, B., Moll, H., & Le Gros, G. (1999). Infection of mice with Mycobacterium bovis-BCG induces both Th1 and Th2 immune responses in the absence of interferon-gamma signalling. European Cytokine Network, 10(2), 147-154.

Kirman, J., McCoy, K. D., Hook, S., Prout, M., Delahunt, B., Orme, I., … Le Gros, G. (1999). CTLA-4 blockade enhances the immune response induced by mycobacterial infection but does not lead to increased protection. Infection & Immunity, 67(8), 3786-3792.

1998

Journal - Research Article

Erb, K. J., Kirman, J., Woodfield, L., Wilson, T., Watson, J. D., & Le Gros, G. (1998). Identification of potential CD8⁺ T-cell epitopes of the 19kDa and AhpC proteins from Mycobacterium tuberculosis: No evidence for CD8⁺ T-cell priming against the identified peptides after DNA-vaccination of mice. Vaccine, 16(7), 692-697.

Erb, K. J., Kirman, J., Delahunt, B., Chen, W. X., & Le Gros, G. (1998). IL-4, IL-5 and IL-10 are not required for the control of M. bovis-BCG infection in mice. Immunology & Cell Biology, 76(1), 41-46. doi: 10.1046/j.1440-1711.1998.00719.x

Journal - Research Other

Kirman, J., & Le Gros, G. (1998). Which is the true regulator of Th₂ cell development in allergic immune responses? [Editorial]. Clinical & Experimental Allergy, 28(8), 908-910. doi: 10.1046/j.1365-2222.1998.00355.x