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Dr Daniel Pletzer

Contact Details

Email
daniel.pletzer@otago.ac.nz
Position
Senior Lecturer
Department
Department of Microbiology and Immunology
Qualifications
PhD
Research summary
Using nanomedicines to combat multidrug resistant WHO-priority pathogens

Research

Our research is focused on recalcitrant ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogens; especially hard-to-treat clinical isolates involved in multidrug resistance, biofilm infections and persistence.

We are especially interested in bacteria that have been categorized as 'critical' priority pathogens by the World Health Organization. This includes multidrug resistant organisms that cause severe and often deadly infections and therefore pose an enormous threat in hospitals.

To address this issue, research in the Pletzer Lab focuses on fighting infectious diseases and tackling antimicrobial resistance using innovative and interdisciplinary approaches.

Our lab seeks to:

  1. Understand how microbes cause disease
  2. Fight antimicrobial resistance with novel nanomedicines
  3. Develop new antimicrobial strategies

Visit www.pletzerlab.com for more information

Visit Daniel Pletzer’s profile in the Department of Microbiology and Immunology.

Scholarly networking websites

Publications

Rajchakit, U., Lamba, S., Wang, K., Lyons, N., Lu, J., Swift, S., Pletzer, D., & Sarojini, V. (2024). Size-controlled synthesis of gold nanoparticles tethering antimicrobial peptides with potent broad-spectrum antimicrobial and antibiofilm activities. Molecular Pharmaceutics. Advance online publication. doi: 10.1021/acs.molpharmaceut.3c00734

Saha, T., Lyons, N., Yung, D. B. Y., Quiñones‑Mateu, M. E., Pletzer, D., & Das, S. C. (2024). Repurposing ebselen as an inhalable dry powder to treat respiratory tract infections. European Journal of Pharmaceutics & Biopharmaceutics, 195, 114170. doi: 10.1016/j.ejpb.2023.12.010

Shein, A. M. S., Wannigama, D. L., Hurst, C., Monk, P. N., Amarasiri, M., Badavath, V. N., … Pletzer, D., … Hosseini Rad, S. M. A., … Abe, S. (2023). Novel intranasal phage-CaEDTA-ceftazidime/avibactam triple combination therapy demonstrates remarkable efficacy in treating Pseudomonas aeruginosa lung infection. Biomedicine & Pharmacotherapy, 168, 115793. doi: 10.1016/j.biopha.2023.115793

Wei, X., Gao, J., Xu, C., Pan, X., Jin, Y., Bai, F., … Lamont, I. L., Pletzer, D., & Wu, W. (2023). Murepavadin induces envelope stress response and enhances the killing efficacies of β-lactam antibiotics by impairing the outer membrane integrity of Pseudomonas aeruginosa. Microbiology Spectrum. Advance online publication. doi: 10.1128/spectrum.01257-23

Wiesmann, C. L., Zhang, Y., Alford, M., Hamilton, C. D., Dosanjh, M., Thoms, D., … Pletzer, D., … Haney, C. H. (2023). The ColR/S two-component system is a conserved determinant of host association across Pseudomonas species. ISME Journal, 17, 286-296. doi: 10.1038/s41396-022-01343-3

Haney, E. F., Pletzer, D., & Hancock, R. E. W. (2021). Impact of host defense peptides on chronic wounds and infections. In M. A. Shiffman & M. Low (Eds.), Chronic wounds, wound dressings and wound healing. (pp. 3-19). Cham, Switzerland: Springer. doi: 10.1007/15695_2017_88

Chapter in Book - Research

Rajchakit, U., Lamba, S., Wang, K., Lyons, N., Lu, J., Swift, S., Pletzer, D., & Sarojini, V. (2024). Size-controlled synthesis of gold nanoparticles tethering antimicrobial peptides with potent broad-spectrum antimicrobial and antibiofilm activities. Molecular Pharmaceutics. Advance online publication. doi: 10.1021/acs.molpharmaceut.3c00734

Journal - Research Article

Saha, T., Lyons, N., Yung, D. B. Y., Quiñones‑Mateu, M. E., Pletzer, D., & Das, S. C. (2024). Repurposing ebselen as an inhalable dry powder to treat respiratory tract infections. European Journal of Pharmaceutics & Biopharmaceutics, 195, 114170. doi: 10.1016/j.ejpb.2023.12.010

Journal - Research Article

Fahma, F., Firmanda, A., Cabral, J., Pletzer, D., Fisher, J., Mahadik, B., … Wulandari, A. (2023). Three-dimensional printed cellulose for wound dressing applications. 3D Printing & Additive Manufacturing, 10(5), 1015-1035. doi: 10.1089/3dp.2021.0327

Journal - Research Article

Shein, A. M. S., Wannigama, D. L., Hurst, C., Monk, P. N., Amarasiri, M., Badavath, V. N., … Pletzer, D., … Hosseini Rad, S. M. A., … Abe, S. (2023). Novel intranasal phage-CaEDTA-ceftazidime/avibactam triple combination therapy demonstrates remarkable efficacy in treating Pseudomonas aeruginosa lung infection. Biomedicine & Pharmacotherapy, 168, 115793. doi: 10.1016/j.biopha.2023.115793

Journal - Research Article

Wei, X., Gao, J., Xu, C., Pan, X., Jin, Y., Bai, F., … Lamont, I. L., Pletzer, D., & Wu, W. (2023). Murepavadin induces envelope stress response and enhances the killing efficacies of β-lactam antibiotics by impairing the outer membrane integrity of Pseudomonas aeruginosa. Microbiology Spectrum. Advance online publication. doi: 10.1128/spectrum.01257-23

Journal - Research Article

Wiesmann, C. L., Zhang, Y., Alford, M., Hamilton, C. D., Dosanjh, M., Thoms, D., … Pletzer, D., … Haney, C. H. (2023). The ColR/S two-component system is a conserved determinant of host association across Pseudomonas species. ISME Journal, 17, 286-296. doi: 10.1038/s41396-022-01343-3

Journal - Research Article

Adhikari, B. R., Sinha, S., Lyons, N., Pletzer, D., Lamont, I., Gordon, K. C., & Das, S. C. (2022). Inhalable ceftazidime-roflumilast powder targeting infection and inflammation: Influence of incorporating roflumilast into ceftazidime-leucine co-amorphous formulation. European Journal of Pharmaceutics & Biopharmaceutics, 180, 260-268. doi: 10.1016/j.ejpb.2022.10.005

Journal - Research Article

Belanger, C. R., Dostert, M., Blimkie, T. M., Lee, A. H.-Y., Dhillon, B. K., Wu, B. C., … Pletzer, D., … Hancock, R. E. W. (2022). Surviving the host: Microbial metabolic genes required for growth of Pseudomonas aeruginosa in physiologically-relevant conditions. Frontiers in Microbiology, 13, 1055512. doi: 10.3389/fmicb.2022.1055512

Journal - Research Article

Esposito, T. V. F., Rodríguez-Rodríguez, C., Blackadar, C., Haney, E. F., Pletzer, D., Hancock, R. E. W., … Häfeli, U. O. (2022). Biodistribution and Toxicity of Innate Defense Regulator 1018 (IDR-1018). European Journal of Pharmaceutics & Biopharmaceutics, 179, 11-25. doi: 10.1016/j.ejpb.2022.08.004

Journal - Research Article

Firmanda, A., Fahma, F., Syamsu, K., Cabral, J., Pletzer, D., & Gustiananda, M. (2022). Cellulose composites containing active constituents of coffee and tea: A prospective novel wound dressing [Review]. Materials Advances, 3, 7463-7483. doi: 10.1039/D2MA00642A

Journal - Research Article

Harfoot, R., Yung, D. B. Y., Anderson, W. A., Wild, C. E. K., Coetzee, N., Hernández, L. C., Lawley, B., Pletzer, D., Derraik, J. G. B., … Quiñones‑Mateu, M. E. (2022). Ultraviolet-C irradiation, heat, and storage as potential methods of inactivating SARS-CoV-2 and bacterial pathogens on filtering facepiece respirators. Pathogens, 11(1), 83. doi: 10.3390/pathogens11010083

Journal - Research Article

Neilsen, J. E., Alford, M. A., Yung, D. B. Y., Molchanova, N., Fortkort, J. A., Lin, J. S., … Pletzer, D., … Barron, A. E. (2022). Self-assembly of antimicrobial peptoids impacts their biological effects on ESKAPE bacterial pathogens. ACS Infectious Diseases, 8, 533-545. doi: 10.1021/acsinfecdis.1c00536

Journal - Research Article

Sousa, M. G. d. C., de Almeida, G. C., Mota, D. C. M., da Costa, R. A., Dias, S. C., Limberger, S. N., … Pletzer, D., … Rezende, T. M. B. (2022). Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures. Bioactive Materials, 16, 173-186. doi: 10.1016/j.bioactmat.2022.01.027

Journal - Research Article

Wolfmeier, H., Wardell, S. J. T., Liu, L. T., Falsafi, R., Draeger, A., Babiychuk, E. B., Pletzer, D., & Hancock, R. E. W. (2022). Targeting the Pseudomonas aeruginosa virulence factor phospholipase C with engineered liposomes. Frontiers in Microbiology, 13, 867449. doi: 10.3389/fmicb.2022.867449

Journal - Research Article

Alford, M. A., Choi, K.-Y. G., Trimble, M. J., Masoudi, H., Kalsi, P., Pletzer, D., & Hancock, R. E. W. (2021). Murine model of sinusitis infection for screening antimicrobial and immunomodulatory therapies. Frontiers in Cellular & Infection Microbiology, 11, 621081. doi: 10.3389/fcimb.2021.621081

Journal - Research Article

Coleman, S. R., Pletzer, D., & Hancock, R. E. W. (2021). Contribution of swarming motility to dissemination in a Pseudomonas aeruginosa murine skin abscess infection model. Journal of Infectious Diseases, 224, 726-733. doi: 10.1093/infdis/jiaa778

Journal - Research Article

Drayton, M., Alford, M. A., Pletzer, D., Haney, E. F., Machado, Y., Luo, H. D., … Straus, S. K. (2021). Enzymatically releasable polyethylene glycol: Host defense peptide conjugates with improved activity and biocompatibility. Journal of Controlled Release, 339, 220-231. doi: 10.1016/j.jconrel.2021.09.035

Journal - Research Article

Khomtchouk, K. M., Joseph, L. I., Khomtchouk, B. B., Kouhi, A., Massa, S., Xia, A., … Pletzer, D., … Santa Maria, P. L. (2021). Treatment with a neutrophil elastase inhibitor and ofloxacin reduces P. aeruginosa burden in a mouse model of chronic suppurative otitis media. npj Biofilms & Microbiomes, 7, 31. doi: 10.1038/s41522-021-00200-z

Journal - Research Article

Pletzer, D., Asnis, J., Slavin, Y. N., Hancock, R. E. W., Bach, H., Saatchi, K., & Häfeli, H. O. (2021). Rapid microwave-based method for the preparation of antimicrobial lignin-capped silver nanoparticles active against multidrug-resistant bacteria. International Journal of Pharmaceutics, 596, 120299. doi: 10.1016/j.ijpharm.2021.120299

Journal - Research Article

Ren, H., Zhang, J., Zhou, J., Xu, C., Fang, Z., Pan, X., … Pletzer, D., & Wu, W. (2021). Synergistic bactericidal activities of tobramycin with ciprofloxacin and azithromycin against Klebsiella pneumoniae. Journal of Antibiotics, 74, 528-537. doi: 10.1038/s41429-021-00427-0

Journal - Research Article

Wilkinson, L. V., Alford, M. A., Coleman, S. R., Wu, B. C., Lee, A. H. Y., Blimkie, T. M., … Pletzer, D., & Hancock, R. E. W. (2021). Peptide 1018 inhibits swarming and influences Anr-regulated gene expression downstream of the stringent stress response in Pseudomonas aeruginosa. PLoS ONE, 16(4), e0250977. doi: 10.1371/journal.pone.0250977

Journal - Research Article

Wu, B., Haney, E. F., Akhoundsadegh, N., Pletzer, D., Trimble, M. J., Adriaans, A. E., … Hancock, R. E. W. (2021). Human organoid biofilm model for assessing antibiofilm activity of novel agents. npj Biofilms & Microbiomes, 7(1), 8. doi: 10.1038/s41522-020-00182-4

Journal - Research Article

Alford, M. A., Baghela, A., Yeung, A. T. Y., Pletzer, D., & Hancock, R. E. W. (2020). NtrBC regulates invasiveness and virulence of Pseudomonas aeruginosa during high-density infection. Frontiers in Microbiology, 11. doi: 10.3389/fmicb.2020.00773

Journal - Research Article

Belanger, C. R., Lee, A. H.-Y., Pletzer, D., Dhillon, B. K., Falsafi, R., & Hancock, R. E. W. (2020). Identification of novel targets of azithromycin activity against Pseudomonas aeruginosa grown in physiologically relevant media. PNAS, 117(2), 33519-33529. doi: 10.1073/pnas.2007626117

Journal - Research Article

Copp, J. N., Pletzer, D., Brown, A. S., van der Heijden, J., Miton, C. M., Rich, M. H., … Ackerley, D. F. (2020). Mechanistic understanding enables the rational design of salicylanilide combination therapies for gram-negative infections. mBio, 11(5), e02068-20. doi: 10.1128/mBio.02068-20

Journal - Research Article

Etayash, H., Pletzer, D., Kumar, P., Straus, S. K., & Hancock, R. E. W. (2020). Cyclic derivative of host-defense peptide IDR-1018 improves proteolytic stability, suppresses inflammation, and enhances in vivo activity. Journal of Medicinal Chemistry, 63(17), 9228-9236. doi: 10.1021/acs.jmedchem.0c00303

Journal - Research Article

Etayash, H., Qian, Y., Pletzer, D., Zhang, Q., Xie, J., Cui, R., … Hancock, R. E. W. (2020). Host defense peptide-mimicking amphiphilic β-peptide polymer (Bu:DM) exhibiting anti-biofilm, immunomodulatory, and in Vivo anti-infective activity. Journal of Medicinal Chemistry, 63, 12921-12928. doi: 10.1021/acs.jmedchem.0c01321

Journal - Research Article

Khomtchouk, K. M., Kouhi, A., Xia, A., Bekale, L. A., Massa, S. M., Sweere, J. M., Pletzer, D., … Santa Maria, P. L. (2020). A novel mouse model of chronic suppurative otitis media and its use in preclinical antibiotic evaluation. Science Advances, 6(33), eabc1828. doi: 10.1126/sciadv.abc1828

Journal - Research Article

Moosavian, M., Emam, N., Pletzer, D., & Savari, M. (2020). Rough-type and loss of the LPS due to lpx genes deletions are associated with colistin resistance in multidrug-resistant clinical Escherichia coli isolates not harbouring mcr genes. PLoS ONE, 15(5), e0233518. doi: 10.1371/journal.pone.0233518

Journal - Research Article

Pletzer, D., Blimkie, T. M., Wolfmeier, H., Li, Y., Baghela, A., Lee, A. H. Y., … Hancock, R. E. W. (2020). The stringent stress response controls proteases and global regulators under optimal growth conditions in Pseudomonas aeruginosa. mSystems, 5(4), e00495-20. doi: 10.1128/mSystems.00495-20

Journal - Research Article

Pletzer, D., Sun, E., Ritchie, C., Wilkinson, L., Liu, L. T., Trimble, M. J., … Hancock, R. E. W. (2020). Surfing motility is a complex adaptation dependent on the stringent stress response in Pseudomonas aeruginosa LESB58. PLoS Pathogens, 16(3), e1008444. doi: 10.1371/journal.ppat.1008444

Journal - Research Article

Kłodzińska, S. N., Pletzer, D., Rahanjam, N., Rades, T., Hancock, R. E. W., & Nielsen, H. M. (2019). Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5. Nanomedicine, 20, 102022. doi: 10.1016/j.nano.2019.102022

Journal - Research Article

Kumar, P., Pletzer, D., Haney, E. F., Rahanjam, N., Cheng, J. T. J., Yue, M., … Straus, S. K. (2019). Aurein-derived antimicrobial peptides formulated with pegylated phospholipid micelles to target methicillin-resistant Staphylococcus aureus skin infections. ACS Infectious Diseases, 5, 443-453. doi: 10.1021/acsinfecdis.8b00319

Journal - Research Article

Woehlk, H., Trimble, M. J., Mansour, S. C., Pletzer, D., Trouillet, V., Welle, A., … Fairfull-Smith, K. E. (2019). Controlling biofilm formation with nitroxide functional surfaces. Polymer Chemistry, 10(31), 4252-4258. doi: 10.1039/c9py00690g

Journal - Research Article

Luscher, A., Moynié, L., Auguste, P. S., Bumann, D., Mazza, L., Pletzer, D., … Köhler, T. (2018). TonB-dependent receptor repertoire of Pseudomonas aeruginosa for uptake of siderophore-drug conjugates. Antimicrobial Agents & Chemotherapy, 62(6), e00097-18. doi: 10.1128/AAC.00097-18

Journal - Research Article

Pletzer, D., Mansour, S. C., & Hancock, R. E. W. (2018). Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens. PLoS Pathogens, 14(6), e1007084. doi: 10.1371/journal.ppat.1007084

Journal - Research Article

Windham, I. H., Servetas, S. L., Whitmire, J. M., Pletzer, D., Hancock, R. E. W., & Merrell, D. S. (2018). Helicobacter pylori biofilm formation is differentially affected by common culture conditions, and proteins play a central role in the biofilm matrix. Applied & Environmental Microbiology, 84(14), e00391-18. doi: 10.1128/AEM.00391-18

Journal - Research Article

Wolfmeier, H., Mansour, S. C., Liu, L. T., Pletzer, D., & Draeger, A. (2018). Liposomal therapy attenuates dermonecrosis induced by community-associated methicillin-resistant Staphylococcus aureus by targeting α-type phenol-soluble modulins and α-hemolysin. EBioMedicine, 33, 211-217. doi: 10.1016/j.ebiom.2018.06.016

Journal - Research Article

Wolfmeier, H., Pletzer, D., Mansour, S. C., & Hancock, R. E. W. (2018). New perspectives in biofilm eradication. ACS Infectious Diseases, 4(2), 93-106. doi: 10.1021/acsinfecdis.7b00170

Journal - Research Article

Chalhoub, H., Pletzer, D., Weingart, H., Braun, Y., Tunney, M. M., Elborn, J. S., … Van Bambeke, F. (2017). Mechanisms of intrinsic resistance and acquired susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients to temocillin, a revived antibiotic. Scientific Reports, 7, 40208. doi: 10.1038/srep40208

Journal - Research Article

Moynié, L., Luscher, A., Rolo, D., Pletzer, D., Tortajada, A., Weingart, H., … Köhler, T. (2017). Structure and function of the PiuA and PirA siderophore-drug receptors from Pseudomonas aeruginosa and Acinetobacter baumannii. Antimicrobial Agents & Chemotherapy, 61, e02531-16. doi: 10.1128/AAC.02531-16

Journal - Research Article

Pletzer, D., Mansour, S. C., Wuerth, K., Rahanjam, N., & Hancock, R. E. W. (2017). New mouse model for chronic infections by gram-negative bacteria enabling the study of anti-infective efficacy and host-microbe interactions. mBio, 8(1), e00140-17. doi: 10.1128/mBio.00140-17

Journal - Research Article

Pletzer, D., Wolfmeier, H., Bains, M., & Hancock, R. E. W. (2017). Synthetic peptides to target stringent response-controlled virulence in a Pseudomonas aeruginosa murine cutaneous infection model. Frontiers in Microbiology, 8, 1867. doi: 10.3389/fmicb.2017.01867

Journal - Research Article

Pothula, K. R., Dhanasekar, N. N., Lamichhane, U., Younas, F., Pletzer, D., Benz, R., … Kleinekathöfer, U. (2017). Single residue acts as gate in OccK channels. Journal of Physical Chemistry B, 121, 2614-2621. doi: 10.1021/acs.jpcb.7b01787

Journal - Research Article

Abdallah, K., Hartman, K., Pletzer, D., Zhurina, D., & Ullrich, M. S. (2016). The bacteriophage-derived transcriptional regulator, LscR, activates the expression of levansucrase genes in Pseudomonas syringae. Molecular Microbiology, 102(6), 1062-1074. doi: 10.1111/mmi.13536

Journal - Research Article

Ganguly, S., Jimenez-Galisteo, G., Pletzer, D., Winterhalter, M., Benz, R., & Viñas, M. (2016). Draft genome sequence of Dietzia maris DSM 43672, a Gram-positive bacterium of the mycolata group. Genome Announcements, 4(3), e00542-16. doi: 10.1128/genomeA.00542-16

Journal - Research Article

Mansour, S. C., Pletzer, D., de la Fuente-Núñez, C., Kim, P., Cheung, G. Y. C., Joo, H.-S., … Hancock, R. E. W. (2016). Bacterial abscess formation is controlled by the stringent stress response and can be targeted therapeutically. EBioMedicine, 12, 219-226. doi: 10.1016/j.ebiom.2016.09.015

Journal - Research Article

Pletzer, D., Braun, Y., & Weingart, H. (2016). Swarming motility is modulated by expression of the putative xenosiderophore transporter SppR-SppABCD in Pseudomonas aeruginosa PA14. Antonie van Leeuwenhoek, 109, 737-753. doi: 10.1007/s10482-016-0675-8

Journal - Research Article

Pletzer, D., Coleman, S. R., & Hancock, R. E. W. (2016). Anti-biofilm peptides as a new weapon in antimicrobial warfare. Current Opinion in Microbiology, 33, 35-40. doi: 10.1016/j.mib.2016.05.016

Journal - Research Article

Mehmood, A., Abdallah, K., Khandekar, S., Zhurina, D., Srivastava, A., Al-Karablieh, N., … Pletzer, D., & Ullrich, M. S. (2015). Expression of extra-cellular levansucrase in Pseudomonas syringae is controlled by the in planta fitness-promoting metabolic repressor HexR. BMC Microbiology, 15, 48. doi: 10.1186/s12866-015-0349-0

Journal - Research Article

Pletzer, D., Braun, Y., Dubiley, S., Lafon, C., Köhler, T., Page, M. G. P., … Weingart, H. (2015). The Pseudomonas aeruginosa PA14 ABC transporter NppA1A2BCD is required for uptake of peptidyl nucleoside antibiotics. Journal of Bacteriology, 197(13), 2217-2228. doi: 10.1128/JB.00234-15

Journal - Research Article

Pletzer, D., Stahl, A., Oja, A. E., & Weingart, H. (2015). Role of the cell envelope stress regulators BaeR and CpxR in control of RND-type multidrug efflux pumps and transcriptional cross talk with exopolysaccharide synthesis in Erwinia amylovora. Archives of Microbiology, 197, 761-772. doi: 10.1007/s00203-015-1109-0

Journal - Research Article

Stahl, A., Pletzer, D., Mehmood, A., & Ullrich, M. S. (2015). Marinobacter adhaerens HP15 harbors two CzcCBA efflux pumps involved in zinc detoxification. Antonie van Leeuwenhoek, 108, 649-658. doi: 10.1007/s10482-015-0520-5

Journal - Research Article

Johnston, C. D., Bannantine, J. P., Govender, R., Endersen, L., Pletzer, D., Weingart, H., … Sleator, R. D. (2014). Enhanced expression of codon optimized Mycobacterium avium subsp. paratuberculosis antigens in Lactobacillus salivarius. Frontiers in Cellular & Infection Microbiology, 4, 120. doi: 10.3389/fcimb.2014.00120

Journal - Research Article

Karar, M. G. E., Pletzer, D., Jaiswal, R., Weingart, H., & Kuhnert, N. (2014). Identification, characterization, isolation and activity against Escherichia coli of quince (Cydonia oblonga) fruit polyphenols. Food Research International, 65(A), 121-129. doi: 10.1016/j.foodres.2013.10.040

Journal - Research Article

Khandekar, S., Srivastava, A., Pletzer, D., Stahl, A., & Ullrich, M. S. (2014). The conserved upstream region of lscB/C determines expression of different levansucrase genes in plant pathogen Pseudomonas syringae. BMC Microbiology, 14, 79. doi: 10.1186/1471-2180-14-79

Journal - Research Article

Pletzer, D., & Weingart, H. (2014). Characterization and regulation of the Resistance-Nodulation-Cell Division-type multidrug efflux pumps MdtABC and MdtUVW from the fire blight pathogen Erwinia amylovora. BMC Microbiology, 14, 185. doi: 10.1186/1471-2180-14-185

Journal - Research Article

Pletzer, D., & Weingart, H. (2014). Characterization of AcrD, a Resistance-Nodulation-Cell Division-type multidrug efflux pump from the fire blight pathogen Erwinia amylovora. BMC Microbiology, 14, 13. doi: 10.1186/1471-2180-14-13

Journal - Research Article

Pletzer, D., Lafon, C., Braun, Y., Köhler, T., Page, M. G. P., Mourez, M., & Weingart, H. (2014). High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in pseudomonas aeruginosa. PLoS ONE, 9(10), e111311. doi: 10.1371/journal.pone.0111311

Journal - Research Article

Pletzer, D., Schweizer, G., & Weingart, H. (2014). AraC/XylS family stress response regulators Rob, SoxS, PliA, and OpiA in the fire blight pathogen Erwinia amylovora. Journal of Bacteriology, 196(17), 3098-3110. doi: 10.1128/JB.01838-14

Journal - Research Article

Johnston, C., Douarre, P. E., Soulimane, T., Pletzer, D., Weingart, H., MacSharry, J., … O'Mahony, J. (2013). Codon optimisation to improve expression of a Mycobacterium avium ssp. paratuberculosis-specific membrane-associated antigen by Lactobacillus salivarius. Pathogens & Disease, 68, 27-38. doi: 10.1111/2049-632X.12040

Journal - Research Article

Veyrier, F., Pletzer, D., Turenne, C., & Behr, M. A. (2009). Phylogenetic detection of horizontal gene transfer during the step-wise genesis of Mycobacterium tuberculosis. BMC Evolutionary Biology, 9, 196. doi: 10.1186/1471-2148-9-196

Journal - Research Article

Firmanda, A., Syamsu, K., Sari, Y. W., Cabral, J., Pletzer, D., Mahadik, B., … Fahma, F. (2022). 3D printed cellulose based product applications. Materials Chemistry Frontiers, 6, 254-279. doi: 10.1039/d1qm00390a

Journal - Research Other

Yung, D. B. Y., Sircombe, K. J., & Pletzer, D. (2021). Friends or enemies? The complicated relationship between Pseudomonas aeruginosa and Staphylococcus aureus. Molecular Microbiology, 116, 1-15. doi: 10.1111/mmi.14699

Journal - Research Other

Alford, M. A., Pletzer, D., & Hancock, R. E. W. (2019). Dismantling the bacterial virulence program. Microbial Biotechnology, 12(3), 409-413. doi: 10.1111/1751-7915.13388

Journal - Research Other

Pletzer, D., & Hancock, R. E. W. (2018). Is synergy the key to treating high-density infections? Future Microbiology, 13(15), 1629-1632. doi: 10.2217/fmb-2018-0216

Journal - Research Other

Belanger, C. R., Mansour, S. C., Pletzer, D., & Hancock, R. E. W. (2017). Alternative strategies for the study and treatment of clinical bacterial biofilms. Emerging Topics in Life Sciences, 1, 41-53. doi: 10.1042/ETLS20160020

Journal - Research Other

Pletzer, D., & Hancock, R. E. W. (2016). Antibiofilm peptides: Potential as broadspectrum agents. Journal of Bacteriology, 198(19), 2572-2578. doi: 10.1128/JB.00017-16

Journal - Research Other

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