School of Biomedical Sciences

Grattan, D. R., & Ladyman, S. R. (2020). Neurophysiological and cognitive changes in pregnancy. In E. A. P. Steegers, M. J. Cipolla & E. C. Miller (Eds.), Handbook of clinical neurology (Vol. 171): Neurology and pregnancy: Pathophysiology and patient care. (pp. 25-55). Amsterdam, The Netherlands: Elsevier. doi: 10.1016/B978-0-444-64239-4.00002-3

Chapter in Book - Research

Smiley, K. O., Ladyman, S. R., Gustafson, P., Grattan, D. R., & Brown, R. S. E. (2019). Neuroendocrinology and adaptive physiology of maternal care. In L. M. Coolen & D. R. Grattan (Eds.), Neuroendocrine regulation of behavior: Current topics in behavioral neurosciences (Vol. 43). (pp. 161-210). Cham, Switzerland: Springer. doi: 10.1007/7854_2019_122

Chapter in Book - Research

Woodside, B., Augustine, R. A., Ladyman, S. R., Naef, L., & Grattan, D. R. (2008). Role of prolactin in the metabolic adaptations to pregnancy and lactation. In R. S. Bridges (Ed.), Neurobiology of the parental brain. (pp. 249-267). London: Academic Press.

Chapter in Book - Research

Garratt, M., Neyt, C., Ladyman, S. R., Pyrski, M., Zufall, F., & Leinders-Zufall, T. (2023). Sensory detection of female olfactory cues as a central regulator of energy metabolism and body weight in male mice. iScience, 26, 106455. doi: 10.1016/j.isci.2023.106455

Journal - Research Article

Hackwell, E. C. R., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2023). Mechanisms of lactation-induced infertility in female mice. Endocrinology. Advance online publication. doi: 10.1210/endocr/bqad049

Journal - Research Article

Swart, J. M., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2022). Pups and prolactin are rewarding to virgin female and pregnant mice. Journal of Neuroendocrinology, e13232. Advance online publication. doi: 10.1111/jne.13232

Journal - Research Article

Khant Aung, Z., Kokay, I. C., Grattan, D. R., & Ladyman, S. R. (2021). Prolactin-induced adaptation in glucose homeostasis in mouse pregnancy is mediated by the pancreas and not in the forebrain. Frontiers in Endocrinology, 12, 765976. doi: 10.3389/fendo.2021.765976

Journal - Research Article

Ladyman, S. R., & Brooks, V. L. (2021). Central actions of insulin during pregnancy and lactation [Invited review]. Journal of Neuroendocrinology, 33, e12946. doi: 10.1111/jne.12946

Journal - Research Article

Ladyman, S. R., Carter, K. M., Gillett, M. L., Khant Aung, Z., & Grattan, D. R. (2021). A reduction in voluntary physical activity in early pregnancy in mice is mediated by prolactin. eLIFE, 10, e62260. doi: 10.7554/eLife.62260

Journal - Research Article

Ladyman, S. R., Larsen, C. M., Taylor, R. S., Grattan, D. R., & McCowan, L. M. E. (2021). Case–control study of prolactin and placental lactogen in SGA pregnancies. Reproduction & Fertility, 2(4), 244-250. doi: 10.1530/RAF-21-0020

Journal - Research Article

Swart, J. M., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2021). Changes in maternal motivation across reproductive states in mice: A role for prolactin receptor activation on GABA neurons. Hormones & Behavior, 135, 105041. doi: 10.1016/j.yhbeh.2021.105041

Journal - Research Article

Barad, Z., Khant Aung, Z., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2020). Impaired prolactin transport into the brain and functional responses to prolactin in aged male mice. Journal of Neuroendocrinology, 32, e12889. doi: 10.1111/jne.12889

Journal - Research Article

Georgescu, T., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2020). Acute effects of prolactin on hypothalamic prolactin receptor expressing neurones in the mouse. Journal of Neuroendocrinology, 32, e12908. doi: 10.1111/jne.12908

Journal - Research Article

Gustafson, P., Ladyman, S. R., McFadden, S., Larsen, C., Khant Aung, Z., Brown, R. S. E., Bunn, S. J., & Grattan, D. R. (2020). Prolactin receptor-mediated activation of pSTAT5 in the pregnant mouse brain. Journal of Neuroendocrinology, 32, e12901. doi: 10.1111/jne.12901

Journal - Research Article

Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2020). Pregnancy-induced adaptation of central sensitivity to leptin and insulin. Molecular & Cellular Endocrinology, 516, 110933. doi: 10.1016/j.mce.2020.110933

Journal - Research Article

Lopez-Vicchi, F., Ladyman, S. R., Ornstein, A. M., Gustafson, P., Knowles, P., Luque, G. M., Grattan, D. R., & Becu-Villalobos, D. (2020). Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake. FASEB Journal, 34, 3902-3914. doi: 10.1096/fj.201902357R

Journal - Research Article

Aquino, N. S. S., Kokay, I. C., Perez, C. T., Ladyman, S. R., Henriques, P. C., Silva, J. F., … Grattan, D. R., & Szawka, R. E. (2019). Kisspeptin stimulation of prolactin secretion requires Kiss1 receptor but not in tuberoinfundibular dopaminergic neurons. Endocrinology, 160(3), 522-533. doi: 10.1210/en.2018-00932

Journal - Research Article

Augustine, R. A., Knowles, P. J., Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2019). Impaired hypothalamic leptin sensitivity in pseudopregnant rats treated with chronic prolactin to mimic pregnancy. Journal of Neuroendocrinology, 31, e12702. doi: 10.1111/jne.12702

Journal - Research Article

Gustafson, P., Ladyman, S. R., & Brown, R. S. E. (2019). Suppression of leptin transport into the brain contributes to leptin resistance during pregnancy in the mouse. Endocrinology, 160(4), 880-890. doi: 10.1210/en.2018-01065

Journal - Research Article

Ladyman, S. R., Carter, K. M., & Grattan, D. R. (2018). Energy homeostasis and running wheel activity during pregnancy in the mouse. Physiology & Behavior, 194, 83-94. doi: 10.1016/j.physbeh.2018.05.002

Journal - Research Article

Ladyman, S. R., Khant Aung, Z., & Grattan, D. R. (2018). Impact of pregnancy and lactation on the long-term regulation of energy balance in female mice. Endocrinology, 159(6), 2324-2336. doi: 10.1210/en.2018-00057

Journal - Research Article

McEwen, H. J. L., Cognard, E., Ladyman, S. R., Khant-Aung, Z., Tups, A., Shepherd, P. R., & Grattan, D. R. (2018). Feeding and GLP-1 receptor activation stabilize beta-catenin in specific hypothalamic nuclei in male rats. Journal of Neuroendocrinology, 30(6), e12607, 1-10. doi: 10.1111/jne.12607

Journal - Research Article

Augustine, R. A., Ladyman, S. R., Bouwer, G. T., Alyousif, Y., Sapsford, T. J., Scott, V., Kokay, I. C., Grattan, D. R., & Brown, C. H. (2017). Prolactin regulation of oxytocin neurone activity in pregnancy and lactation. Journal of Physiology, 595(11), 3591-3605. doi: 10.1113/jp273712

Journal - Research Article

Brown, R. S. E., Aoki, M., Ladyman, S. R., Phillipps, H. R., Wyatt, A., Boehm, U., & Grattan, D. R. (2017). Prolactin action in the medial preoptic area is necessary for postpartum maternal nursing behavior. PNAS, 114(40), 10779-10784. doi: 10.1073/pnas.1708025114

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2017). Region-specific suppression of hypothalamic responses to insulin to adapt to elevated maternal insulin secretion during pregnancy. Endocrinology, 158(12), 4257-4269. doi: 10.1210/en.2017-00600

Journal - Research Article

Ladyman, S. R., MacLeod, M. A., Khant Aung, Z., Knowles, P., Phillipps, H. R., Brown, R. S. E., & Grattan, D. R. (2017). Prolactin receptors in Rip-cre cells, but not in AgRP neurons, are involved in energy homeostasis. Journal of Neuroendocrinology, 29(10), e12474. doi: 10.1111/jne.12474

Journal - Research Article

Tups, A., Benzler, J., Sergi, D., Ladyman, S. R., & Williams, L. M. (2017). Central regulation of glucose homeostasis. Comprehensive Physiology, 7(2), 741-764. doi: 10.1002/cphy.c160015

Journal - Research Article

Brown, R. S. E., Kokay, I. C., Phillipps, H. R., Yip, S. H., Gustafson, P., Wyatt, A., Larsen, C. M., Knowles, P., Ladyman, S. R., LeTissier, P., & Grattan, D. R. (2016). Conditional deletion of the prolactin receptor reveals functional subpopulations of dopamine neurons in the arcuate nucleus of the hypothalamus. Journal of Neuroscience, 36(35), 9173-9185. doi: 10.1523/jneurosci.1471-16.2016

Journal - Research Article

Brown, R. S. E., Wyatt, A. K., Herbison, R. E., Knowles, P. J., Ladyman, S. R., Binart, N., … Grattan, D. R. (2016). Prolactin transport into mouse brain is independent of prolactin receptor. FASEB Journal, 30(2), 1002-1010. doi: 10.1096/fj.15-276519

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2016). Central effects of leptin on glucose homeostasis are modified during pregnancy in the rat. Journal of Neuroendocrinology, 28(10). doi: 10.1111/jne.12431

Journal - Research Article

Ladyman, S. R., Augustine, R. A., Scherf, E., Phillipps, H. R., Brown, C. H., & Grattan, D. R. (2016). Attenuated hypothalamic responses to α-melanocyte stimulating hormone during pregnancy in the rat. Journal of Physiology, 594(4), 1087-1101. doi: 10.1113/jp271605

Journal - Research Article

Ladyman, S., & Woodside, B. (2014). Food restriction during lactation suppresses Kiss1 mRNA expression and kisspeptin-stimulated LH release in rats. Reproduction, 147, 743-751. doi: 10.1530/rep-13-0426

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2013). JAK-STAT and feeding. JAK-STAT, 2(2), e23675. doi: 10.4161/jkst.23675

Journal - Research Article

Phillipps, H. R., Ladyman, S. R., & Grattan, D. R. (2013). Maintained expression of genes associated with metabolism in the ventromedial hypothalamic nucleus despite development of leptin resistance during pregnancy in the rat. Physiological Reports, 1(6), e00162. doi: 10.1002/phy2.162

Journal - Research Article

Ladyman, S. R., Fieldwick, D. M., & Grattan, D. R. (2012). Suppression of leptin-induced hypothalamic JAK/STAT signaling and feeding response during pregnancy in the mouse. Reproduction, 144(1), 83-90. doi: 10.1530/rep-12-0112

Journal - Research Article

Ladyman, S. R., Sapsford, T. J., & Grattan, D. R. (2011). Loss of acute satiety response to cholecystokinin in pregnant rats. Journal of Neuroendocrinology, 23(11), 1091-1098. doi: 10.1111/j.1365-2826.2011.02191.x

Journal - Research Article

Ladyman, S. R., Augustine, R. A., & Grattan, D. R. (2010). Hormone interactions regulating energy balance during pregnancy. Journal of Neuroendocrinology, 22, 805-817. doi: 10.1111/j.1365-2826.2010.02017.x

Journal - Research Article

Ladyman, S. R., & Woodside, B. (2009). Regulation of maternal food intake and mother-pup interactions by the Y5 receptor. Physiology & Behavior, 97, 91-97. doi: 10.1016/j.physbeh.2009.02.008

Journal - Research Article

Ladyman, S. R., Tups, A., Augustine, R. A., Swahn-Azavedo, A., Kokay, I. C., & Grattan, D. R. (2009). Loss of hypothalamic response to leptin during pregnancy associated with development of melanocortin resistance. Journal of Neuroendocrinology, 21(5), 449-456. doi: 10.1111/j.1365-2826.2009.01862.x

Journal - Research Article

Augustine, R. A., Ladyman, S. R., & Grattan, D. R. (2008). From feeding one to feeding many: Hormone-induced changes in bodyweight homeostasis during pregnancy (Symposium report). Journal of Physiology, 586(2), 387-397. doi: 10.1113/jphysiol.2007.146316

Journal - Research Article

Grattan, D. R., Ladyman, S. R., & Augustine, R. A. (2007). Hormonal induction of leptin resistance during pregnancy. Physiology & Behavior, 91, 366-374.

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2005). Suppression of leptin receptor messenger ribonucleic acid and leptin responsiveness in the ventromedial nucleus of the hypothalamus during pregnancy in the rat. Endocrinology, 146(9), 3868-3874.

Journal - Research Article

Ladyman, S. R., & Grattan, D. R. (2004). Region-specific reduction in leptin-induced phosphorylation of signal transducer and activator of transcription-3 (STAT3) in the rat hypothalamus is associated with leptin resistance during pregnancy. Endocrinology, 145(8), 3704-3711.

Journal - Research Article

Augustine, R. A., Kokay, I. C., Andrews, Z. B., Ladyman, S. R., & Grattan, D. R. (2003). Quantitation of prolactin receptor mRNA in the maternal rat brain during pregnancy and lactation. Journal of Molecular Endocrinology, 31, 221-232.

Journal - Research Article

Todd, B. J., Ladyman, S. R., & Grattan, D. R. (2003). Suppression of pulsatile luteinizing hormone secretion but not luteinizing hormone surge in leptin resistant obese Zucker rats. Journal of Neuroendocrinology, 15, 61-68.

Journal - Research Article

Clarke, G. S., Gatford, K. L., Young, R. L., Grattan, D. R., Ladyman, S. R., & Page, A. J. (2021). Maternal adaptations to food intake across pregnancy: Central and peripheral mechanisms. Obesity, 29(11), 1813-1824. doi: 10.1002/oby.23224

Journal - Research Other

Ladyman, S. R., Hackwell, E. C. R., & Brown, R. S. E. (2020). The role of prolactin in co-ordinating fertility and metabolic adaptations during reproduction. Neuropharmacology, 167, 107911. doi: 10.1016/j.neuropharm.2019.107911

Journal - Research Other

Lopez-Vicchi, F., De Winne, C., Brie, B., Sorianello, E., Ladyman, S. R., & Becu-Villalobos, D. (2020). Metabolic functions of prolactin: Physiological and pathological aspects. Journal of Neuroendocrinology, 32, e12888. doi: 10.1111/jne.12888

Journal - Research Other

Ladyman, S. R. (2019). Anticipating future demands: Hormone-induced transcriptional programming in the maternal pancreas during pregnancy. Endocrinology, 160(5), 1164-1165. doi: 10.1210/en.2019-00243

Journal - Research Other

Ladyman, S. R. (2008). Leptin resistance during pregnancy in the rat. Journal of Neuroendocrinology, 20(269), 269-277. doi: 10.1111/j.1365-2826.2007.01628.x

Journal - Research Other