Introduction to organic synthesis, the synthesis of carbon frameworks and selective manipulation of functional groups. Stereochemical and structural features of synthesis and the structural characterisation of organic compounds.
CHEM 202 Organic Synthesis focuses on fundamental concepts of organic synthesis. The aims of chemical synthesis, construction of carbon frameworks, stereochemical factors and manipulation of functional groups are presented. The determination of structure using spectroscopic techniques, such as infrared and nuclear magnetic resonance spectroscopy, is also addressed. Most concepts are presented in a problem-solving context. CHEM 202 gives an appreciation for obtaining and assessing qualitative information to provide the basis for logically solving problems in organic synthesis.
| Paper title | Organic Chemistry |
|---|---|
| Paper code | CHEM202 |
| Subject | Chemistry |
| EFTS | 0.15 |
| Points | 18 points |
| Teaching period | Semester 1 (On campus) |
| Domestic Tuition Fees (NZD) | $1,141.35 |
| International Tuition Fees | Tuition Fees for international students are elsewhere on this website. |
- Prerequisite
- CHEM 111 or CHEM 191
- Recommended Preparation
- CHEM 111 and CHEM 191
- Schedule C
- Science
- Contact
Associate Professor Bill Hawkins
Tel +64 3 471 6217
Location: Science II, 2N8
bhawkins@chemistry.otago.ac.nz- More information link
- View more information about CHEM 202
- Teaching staff
Course Co-ordinator: Associate Professor Bill Hawkins
Lecturers: Associate Professor Nigel Lucas
Dr Alan Hayman
Dr Andrea Vernall- Paper Structure
The topics covered in CHEM 202, which build on concepts introduced in CHEM 111 and CHEM 191, are:
- Structural characterisation and analysis
- Spectrometric methods for the identification of organic compounds (mass spectrometry, infrared spectroscopy and 13C- and 1H-NMR spectrometry)
- Analysis of molecular conformation and dynamic processes
- Structure and stereochemistry
- Molecular shape
- Rings
- Rigid systems
- Stereochemical control of reactions
- Functional-group
manipulation in aromatic systems
- Molecular orbital description of benzene and aromaticity
- Monosubstituted benzenes
- Substituent effects
- Disubstituted benzene derivatives
- Functional group interconversion
- Nucleophilic aromatic substitution
- Effect of aromatic rings on functional groups
- Constructing
carbon frameworks
- Enolate chemistry
- Main group organometallics (Li, Mg, Cu)
- P and S-Ylids
- Structural characterisation and analysis
- Teaching Arrangements
- There are three lectures, one tutorial and one 4-hour laboratory class each week.
- Textbooks
- Bruice, P.Y. Organic Chemistry, (7th Edn), Prentice-Hall. Highly Recommended
- Graduate Attributes Emphasised
- Interdisciplinary perspective, Lifelong learning, Scholarship, Communication, Critical
thinking, Information literacy, Self-motivation
View more information about Otago's graduate attributes - Learning Outcomes
- Expectations at the completion of the paper:
- An understanding of and an ability to apply the principles of organic synthesis
- An ability to design syntheses of simple molecules
- Laboratory skills associated with organic chemistry and structure determination
- Logical application of chemical knowledge to problem solving
- Students who are majoring in chemistry will have acquired knowledge and skills that will enable them to proceed to 300- and 400-level papers in chemistry
- Students not majoring in chemistry will have acquired knowledge and experimental skills that will serve them in other areas of science
