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Professor Andrew Day

Andrew DayHead of Department / Cure Kids Chair of Paediatric Research at UOC

MB ChB MD FRACP AGAF

Tel +64 3 372 6718
Email andrew.day@otago.ac.nz

Andrew Day trained in paediatrics in Christchurch and undertook further subspeciality training in Toronto, Canada.

After completing clinical and research training in Canada, Professor Day took up a clinical academic position at University of New South Wales, Sydney, Australia.

He returned to the department in 2009 and was appointed to Head of Department in 2010.

Professor Day is a paediatric gastroenterologist.

Research interests

Projects focus

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Publications

Leach, S. T., & Day, A. S. (2019). Enzyme-linked immunosorbent assay to measure S100A12 in fecal samples of children and adults. In C. W. Heizmann (Ed.), Calcium-binding proteins of the EF-hand superfamily: From basics to medical applications: Methods in molecular biology (Vol. 1929). (pp. 755-761). New York, NY: Humana Press. doi: 10.1007/978-1-4939-9030-6_47

Rahmani, J., Kord-Varkaneh, H., Hekmatdoost, A., Thompson, J., Clark, C., Salehisahlabadi, A., Day, A. S., & Jacobson, K. (2019). Body mass index and risk of inflammatory bowel disease: A systematic review and dose-response meta-analysis of cohort studies of over a million participants. Obesity Reviews. Advance online publication. doi: 10.1111/obr.12875

Vernon-Roberts, A., Lopez, R. N., Frampton, C., Gearry, R. B., Lemberg, D. A., & Day, A. S. (2019). A symptom self-report tool for children with inflammatory bowel disease (IBDnow). Journal of Pediatric Gastroenterology & Nutrition. Advance online publication. doi: 10.1097/MPG.0000000000002329

Karim, S., Porter, J. A., McCombie, A., Gearry, R. B., & Day, A. S. (2019). Transition clinics: An observational study of themes important to young people with inflammatory bowel disease. Translational Pediatrics, 8(1), 83-89. doi: 10.21037/tp.2019.01.04

Martin, N. G., Rigterink, T., Adamji, M., Wall, C. L., & Day, A. S. (2019). Single high-dose oral vitamin D3 treatment in New Zealand children with inflammatory bowel disease. Translational Pediatrics, 8(1), 35-41. doi: 10.21037/tp.2018.11.01

Chapter in Book - Research

Leach, S. T., & Day, A. S. (2019). Enzyme-linked immunosorbent assay to measure S100A12 in fecal samples of children and adults. In C. W. Heizmann (Ed.), Calcium-binding proteins of the EF-hand superfamily: From basics to medical applications: Methods in molecular biology (Vol. 1929). (pp. 755-761). New York, NY: Humana Press. doi: 10.1007/978-1-4939-9030-6_47

von der Weid, P.-Y., & Day, A. S. (2018). Pediatric lymphatic development and intestinal lymphangiectasia. In M. J. Caplan (Ed.), Reference module in biomedical sciences. Elsevier. doi: 10.1016/B978-0-12-801238-3.66051-8

Day, A. S., & Robinson, S. J. (2013). Complementary and alternative medicine use in children with inflammatory bowel disease. In K. R. Carter & G. E. Murphy (Eds.), Alternative medicine: Practices, health benefits and controversies. (pp. 107-116). Nova Science.

Beasley, S., & Day, A. (2012). Abdominal pain and vomiting. In M. South & D. Isaacs (Eds.), Practical paediatrics. (7th ed.) (pp. 706-714). Edinburgh, UK: Churchill Livingstone.

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Chapter in Book - Other

Day, A. (2013). Paediatrics. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 41-44). Christchurch, New Zealand: University of Otago.

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Journal - Research Article

Rahmani, J., Kord-Varkaneh, H., Hekmatdoost, A., Thompson, J., Clark, C., Salehisahlabadi, A., Day, A. S., & Jacobson, K. (2019). Body mass index and risk of inflammatory bowel disease: A systematic review and dose-response meta-analysis of cohort studies of over a million participants. Obesity Reviews. Advance online publication. doi: 10.1111/obr.12875

Martin, N. G., Rigterink, T., Adamji, M., Wall, C. L., & Day, A. S. (2019). Single high-dose oral vitamin D3 treatment in New Zealand children with inflammatory bowel disease. Translational Pediatrics, 8(1), 35-41. doi: 10.21037/tp.2018.11.01

Karim, S., Porter, J. A., McCombie, A., Gearry, R. B., & Day, A. S. (2019). Transition clinics: An observational study of themes important to young people with inflammatory bowel disease. Translational Pediatrics, 8(1), 83-89. doi: 10.21037/tp.2019.01.04

Vernon-Roberts, A., Lopez, R. N., Frampton, C., Gearry, R. B., Lemberg, D. A., & Day, A. S. (2019). A symptom self-report tool for children with inflammatory bowel disease (IBDnow). Journal of Pediatric Gastroenterology & Nutrition. Advance online publication. doi: 10.1097/MPG.0000000000002329

Wall, C. L., McCombie, A. M., Gearry, R. B., & Day, A. S. (2019). Newly diagnosed Crohn's disease treated with standard care or enteral nutrition: Psychological outcomes over 6 months. Inflammatory Intestinal Diseases, 4(1), 7-13. doi: 10.1159/000497323

Lawley, M., Wu, J. W., Navas-López, V. M., Huynh, H. Q., Carroll, M. W., Chen, M., … Day, A. S., … Wine, E. (2018). Global variation in use of enteral nutrition for pediatric Crohn disease. Journal of Pediatric Gastroenterology & Nutrition, 67(2), e22-e29. doi: 10.1097/mpg.0000000000001946

Lopez, R. N., Evans, H. M., Appleton, L., Bishop, J., Chin, S., Mouat, S., Gearry, R. B., & Day, A. S. (2018). Prospective incidence of paediatric inflammatory bowel disease in New Zealand in 2015: Results from the Paediatric Inflammatory Bowel Disease in New Zealand (PINZ) Study. Journal of Pediatric Gastroenterology & Nutrition, 66(5), e122-e126. doi: 10.1097/mpg.0000000000001806

Moeeni, V., Walls, T., & Day, A. S. (2018). A retrospective comparison between the PNST and other paediatric nutritional screening tools. International Journal of Child Health & Nutrition, 7(3), 97-101. doi: 10.6000/1929-4247.2018.07.03.1

Porter, J. A., MacKenzie, K. E., Darlow, B. A., Butler, R., & Day, A. S. (2018). Gastric emptying in children with type 1 diabetes mellitus: A pilot study. Journal of Paediatrics & Child Health. Advance online publication. doi: 10.1111/jpc.14215

Ho, S. S. C., & Day, A. S. (2018). Exclusive enteral nutrition in children with inflammatory bowel disease: Physician perspectives and practice. JGH Open. Advance online publication. doi: 10.1002/jgh3.12121

Lopez, R. N., Appleton, L., Gearry, R. B., & Day, A. S. (2018). Rising incidence of paediatric inflammatory bowel disease in Canterbury, New Zealand, 1996-2015. Journal of Pediatric Gastroenterology & Nutrition, 66(2), e45-e50. doi: 10.1097/mpg.0000000000001688

Garg, M., Leach, S. T., Pang, T., Needham, B., Coffey, M. J., Katz, T., … Day, A. S., … Ooi, C. Y. (2018). Age-related levels of fecal M2-pyruvate kinase in children with cystic fibrosis and healthy children 0 to 10 years old. Journal of Cystic Fibrosis, 17(1), 109-113. doi: 10.1016/j.jcf.2017.07.011

Day, A. S., Gulati, A. S., Patel, N., Boyle, B., Park, K. T., & Saeed, S. A. (2018). The role of combination therapy in pediatric inflammatory bowel disease (IBD): A clinical report from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Journal of Pediatric Gastroenterology & Nutrition, 66(2), 361-368. doi: 10.1097/mpg.0000000000001850

Alhagamhmad, M. H., Lemberg, D. A., Day, A. S., Tan, L.-Z., Ooi, C. Y., Krishnan, U., … Leach, S. T. (2017). Advancing nutritional therapy: A novel polymeric formulation attenuates intestinal inflammation in a murine colitis model and suppresses pro-inflammatory cytokine production in ex-vivo cultured inflamed colonic biopsies. Clinical Nutrition, 36(2), 497-505. doi: 10.1016/j.clnu.2016.01.010

Budd, G. R., Aitchison, A., Day, A. S., & Keenan, J. I. (2017). The effect of polymeric formula on enterocyte differentiation. Innate Immunity, 23(3), 240-248. doi: 10.1177/1753425916689333

Flores, S. E., Aitchison, A., Day, A. S., & Keenan, J. I. (2017). Helicobacter pylori infection perturbs iron homeostasis in gastric epithelial cells. PLoS ONE, 12(9), e0184026. doi: 10.1371/journal.pone.0184026

Alhagamhmad, M. H., Day, A. S., Lemberg, D. A., & Leach, S. T. (2017). Exploring and enhancing the anti-inflammatory properties of polymeric formula. Journal of Parenteral & Enteral Nutrition, 41(3), 436-445. doi: 10.1177/0148607115625627

Holtman, G. A., Lisman-van Leeuwen, Y., Day, A. S., Fagerberg, U. L., Henderson, P., Leach, S. T., … Berger, M. Y. (2017). Use of laboratory markers in addition to symptoms for diagnosis of inflammatory bowel disease in children: A meta-analysis of individual patient data. JAMA Pediatrics, 171(10), 984-991. doi: 10.1001/jamapediatrics.2017.1736

Bowden, M. R., Ee, L. C., Krishnan, U., O'Loughlin, E. V., Hardikar, W., Carmody, D., … Day, A. S., … Hazell, P. (2017). Family impact and infant emotional outcomes following diagnosis of serious liver disease or transplantation in infancy. Journal of Pediatric Gastroenterology & Nutrition, 64(4), 528-532. doi: 10.1097/mpg.0000000000001404

Aggarwal, V., Day, A. S., Connor, S., Leach, S. T., Brown, G., Singh, R., … Craig, P. I. (2017). Role of capsule endoscopy and fecal biomarkers in small-bowel Crohn's disease to assess remission and predict relapse. Gastrointestinal Endoscopy, 86(6), 1070-1078. doi: 10.1016/j.gie.2017.09.011

Duvoisin, G., Lopez, R. N., Day, A. S., Lemberg, D. A., Gearry, R. B., & Leach, S. T. (2017). Novel biomarkers and the future potential of biomarkers in inflammatory bowel disease. Mediators of Inflammation, 2017, 1936315. doi: 10.1155/2017/1936315

Wall, C. L., Gearry, R. B., & Day, A. S. (2017). Treatment of active Crohn's disease with exclusive and partial enteral nutrition: A pilot study in adults. Inflammatory Intestinal Diseases, 2(4), 219-227. doi: 10.1159/000489630

Chae, A., Aitchison, A., Day, A. S., & Keenan, J. I. (2017). Bovine colostrum demonstrates anti-inflammatory and antibacterial activity in in vitro models of intestinal inflammation and infection. Journal of Functional Foods, 28, 293-298. doi: 10.1016/j.jff.2016.11.016

Garg, M., Leach, S. T., Coffey, M. J., Katz, T., Strachan, R., Pang, T., … Day, A. S., Appleton, L., Moeeni, V., … Ooi, C. Y. (2017). Age-dependent variation of fecal calprotectin in cystic fibrosis and healthy children. Journal of Cystic Fibrosis, 16(5), 631-636. doi: 10.1016/j.jcf.2017.03.010

Lopez, R. N., Evans, H. M., Appleton, L., Bishop, J., Chin, S., Mouat, S., Gearry, R. B., & Day, A. S. (2017). Point prevalence of pediatric inflammatory bowel disease in New Zealand in 2015: Initial results from the PINZ study. Inflammatory Bowel Diseases, 23(8), 1418-1424. doi: 10.1097/mib.0000000000001138

Day, A. S., Mylvaganam, G., Shalloo, N., Clarkson, C., Leach, S. T., & Lemberg, D. A. (2017). Assessment of disease-specific knowledge in Australian children with inflammatory bowel disease and their parents. Journal of Paediatrics & Child Health, 53(8), 778-781. doi: 10.1111/jpc.13544

Nightingale, S., Storman, M. O., O'Loughlin, E. V., Shun, A., Thomas, G., Benchimol, E. I., Day, A. S., … Ng, V. L. (2017). Early posthepatoportoenterostomy predictors of native liver survival in biliary atresia. Journal of Pediatric Gastroenterology & Nutrition, 64(2), 203-209. doi: 10.1097/mpg.0000000000001289

Nielsen, S., Needham, B., Leach, S. T., Day, A. S., Jaffe, A., Thomas, T., & Ooi, C. Y. (2016). Disrupted progression of the intestinal microbiota with age in children with cystic fibrosis. Scientific Reports, 6, 24857. doi: 10.1038/srep24857

Wright, E. K., Kamm, M. A., De Cruz, P., Hamilton, A. L., Ritchie, K. J., Keenan, J. I., … Burgess, L., Aitchison, A., … Day, A. S., & Gearry, R. B. (2016). Comparison of fecal inflammatory markers in Crohn's disease. Inflammatory Bowel Diseases, 22(5), 1086-1094. doi: 10.1097/mib.0000000000000671

De Voogd, F. A. E., Gearry, R. B., Mulder, C. J., & Day, A. S. (2016). Osteoprotegerin: A novel biomarker for inflammatory bowel disease and gastrointestinal carcinoma. Journal of Gastroenterology & Hepatology, 31, 1386-1392. doi: 10.1111/jgh.13324

Andre, M., & Day, A. S. (2016). Causes of prolonged jaundice in infancy: 3-year experience in a tertiary paediatric centre. New Zealand Medical Journal, 129(1429), 14-21. Retrieved from https://www.nzma.org.nz/journal

Kaakoush, N. O., Thomas, D. S., Ruzayqat, M. M., Lynch, D., Leach, S. T., Lemberg, D. A., Day, A. S., & Mitchell, H. M. (2016). Campylobacter concisus utilizes blood but not short chain fatty acids despite showing associations with Firmicutes taxa. Microbiology, 162(8), 1388-1397. doi: 10.1099/mic.0.000328

Day, A. S., Hamilton, D., Leach, S. T., & Lemberg, D. A. (2016). Inflammatory markers in children with newly diagnosed inflammatory bowel disease. Journal of Gastroenterology & Hepatology Research, 5(4), 2132-2135. doi: 10.17554/j.issn.2224-3992.2016.05.647

Su, H. Y., Gupta, V., Day, A. S., & Gearry, R. B. (2016). Rising incidence of inflammatory bowel disease in Canterbury, New Zealand. Inflammatory Bowel Diseases, 22(9), 2238-2244. doi: 10.1097/mib.0000000000000829

Kaakoush, N. O., Day, A. S., Leach, S. T., Lemberg, D. A., Nielsen, S., & Mitchell, H. M. (2015). Effect of exclusive enteral nutrition on the microbiota of children with newly diagnosed Crohn's disease. Clinical & Translational Gastroenterology, 6, e71. doi: 10.1038/ctg.2014.21

Ledder, O., Lemberg, D. A., & Day, A. S. (2015). Thiopurine-induced pancreatitis in inflammatory bowel diseases. Expert Review of Gastroenterology & Hepatology, 9(4), 399-403. doi: 10.1586/17474124.2015.992879

Pang, T., Leach, S. T., Katz, T., Jaffe, A., Day, A. S., & Ooi, C. Y. (2015). Elevated fecal M2-pyruvate kinase in children with cystic fibrosis: A clue to the increased risk of intestinal malignancy in adulthood? Journal of Gastroenterology & Hepatology, 30(5), 866-871. doi: 10.1111/jgh.12842

Bowden, M. R., Storman, M., Hardikar, W., Ee, L. C., Krishnan, U., Carmody, D., … Day, A. S., … Hazell, P. (2015). Family adjustment and parenting stress when an infant has serious liver disease: The Australian experience. Journal of Pediatric Gastroenterology & Nutrition, 60, 717-722. doi: 10.1097/mpg.0000000000000742

Lemberg, D. A., & Day, A. S. (2015). Crohn disease and ulcerative colitis in children: An update for 2014. Journal of Paediatrics & Child Health, 51, 266-270. doi: 10.1111/jpc.12685

Leach, S. T., Lui, K., Naing, Z., Dowd, S. E., Mitchell, H. M., & Day, A. S. (2015). Multiple opportunistic pathogens, but not pre-existing inflammation, may be associated with necrotizing enterocolitis. Digestive Diseases & Sciences, 60(12), 3728-3734. doi: 10.1007/s10620-015-3830-6

Alhagamhmad, M. H., Leach, S. T., Lemberg, D. A., & Day, A. S. (2015). Changing patterns in the epidemiology of Crohn disease. Journal of Gastroenterology & Hepatology Research, 4(11), 1805-1809. doi: 10.17554/j.issn.2224-3992.2015.04.550

Kaakoush, N. O., Castaño-Rodríguez, N., Day, A. S., Lemberg, D. A., Leach, S. T., & Mitchell, H. M. (2015). Faecal levels of zonula occludens toxin in paediatric patients with Crohn's disease and their association with the intestinal microbiota. Journal of Medical Microbiology, 64(3), 303-306. doi: 10.1099/jmm.0.000005

Wright, E. K., Kamm, M. A., De Cruz, P., Hamilton, A. L., Ritchie, K. J., Krejany, E. O., … Day, A. S., … Gearry, R. B. (2015). Measurement of fecal calprotectin improves monitoring and detection of recurrence of Crohn's disease following surgery. Gastroenterology, 148, 938-947. doi: 10.1053/j.gastro.2015.01.026

Shepherd, D., Day, A. S., Leach, S. T., Lopez, R., Messenger, R., Woodhead, H. J., … Lemberg, D. A. (2015). Single high-dose oral vitamin D3 therapy (Stoss): A solution to vitamin D deficiency in children with inflammatory bowel disease? Journal of Pediatric Gastroenterology & Nutrition, 61(4), 411-414. doi: 10.1097/mpg.0000000000000823

Kho, A., Whitehead, M., & Day, A. S. (2015). Coeliac disease in children in Christchurch, New Zealand: Presentation and patterns from 2000-2010. World Journal of Clinical Pediatrics, 4(4), 148-154. doi: 10.5409/wjcp.v4.i4.148

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