MA BChir MA MD(Camb) FRCP FRACP FRCPCHBrian Darlow trained at Cambridge University, elsewhere in the United Kingdom and New Zealand, with a spell in Papua New Guinea.
He returned to the department as Senior Lecturer in 1982 and was appointed to the Chair of Paediatrics in 2001. From 2007 until 2018 Brian held the Cure Kids Chair of Paediatric Research at the University of Otago, Christchurch.
Through most of his career he has worked as a clinical neonatologist and his research interests include free radical disease in the newborn, the epidemiology and outcome of complications of prematurity, and neonatal networking.
Interests outside of medicine include ornithology and tramping.
Read about the NZ Very Low Birthweight study
Publications
Crowther, C. A., Ashwood, P., Middleton, P. F., McPhee, A., Tan, T., Harding, J. E., for the MAGENTA Study Group, including Austin, N., Darlow, B. A., Dixon, B., Gullam, J., Leishman, D., Dawson, P., Devenish, C., Gaerty, K., Tomlinson, P. A., & Miller, H. (2023). Prenatal intravenous magnesium at 30-34 weeks' gestation and neurodevelopmental outcomes in offspring: The MAGENTA randomized clinical trial. JAMA, 330(7), 603-614. doi: 10.1001/jama.2023.12357
Journal - Research Article
Darlow, B. A. (2023). Primary prevention of ROP: More can be done in all settings. Expert Review of Ophthalmology. Advance online publication. doi: 10.1080/17469899.2023.2245143
Journal - Research Other
Cameron, V. A., Jones, G. T., Horwood, L. J., Pilbrow, A. P., Martin, J., Frampton, C., Ip, W. T., Troughton, R. W., Greer, C., Yang, J., Epton, M. J., Harris, S. L., & Darlow, B. A. (2023). DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight. Clinical Epigenetics, 15, 47. doi: 10.1186/s13148-023-01463-3
Journal - Research Article
Bolbocean, C., van der Pal, S., van Buuren, S., Anderson, P. J., Bartmann, P., Baumann, N., … Darlow, B. A., … Horwood, J., … Woodward, L., … Petrou, S. (2023). Health-related quality-of-life outcomes of very preterm or very low birth weight adults: Evidence from an individual participant data meta-analysis. Pharmacoeconomics, 41, 93-105. doi: 10.1007/s40273-022-01201-2
Journal - Research Article
Robinson, R., Girchenko, P., Pulakka, A., Heinonen, K., Lähdepuro, A., Lahti-Pulkkinen, M., … Darlow, B. A., … Horwood, L. J., … Räikkönen, K. (2023). ADHD symptoms and diagnosis in adult preterms: Systematic review, IPD meta-analysis, and register-linkage study. Pediatric Research, 93, 1399-1409. doi: 10.1038/s41390-021-01929-1
Journal - Research Article
Darlow, B. (2012). The newborn infant: Stabilization and examination. In M. South & D. Isaacs (Eds.), Practical paediatrics. (7th ed.) (pp. 328-340). Edinburgh, UK: Churchill Livingstone.
Chapter in Book - Research
Begg, E. J., Atkinson, H. C., & Darlow, B. A. (1997). Guide to drug usage in lactation. In T. M. Speight & N. H. G. Holford (Eds.), Avery's Drug Treatment: a Guide to the Properties, Choice, Therapeutic Use and Economic Value of Drugs in Disease Management, 4th edition. (pp. 1701-1723). Auckland: Adis Press.
Chapter in Book - Research
Bolbocean, C., van der Pal, S., van Buuren, S., Anderson, P. J., Bartmann, P., Baumann, N., … Darlow, B. A., … Horwood, J., … Woodward, L., … Petrou, S. (2023). Health-related quality-of-life outcomes of very preterm or very low birth weight adults: Evidence from an individual participant data meta-analysis. Pharmacoeconomics, 41, 93-105. doi: 10.1007/s40273-022-01201-2
Journal - Research Article
Cameron, V. A., Jones, G. T., Horwood, L. J., Pilbrow, A. P., Martin, J., Frampton, C., Ip, W. T., Troughton, R. W., Greer, C., Yang, J., Epton, M. J., Harris, S. L., & Darlow, B. A. (2023). DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight. Clinical Epigenetics, 15, 47. doi: 10.1186/s13148-023-01463-3
Journal - Research Article
Crowther, C. A., Ashwood, P., Middleton, P. F., McPhee, A., Tan, T., Harding, J. E., for the MAGENTA Study Group, including Austin, N., Darlow, B. A., Dixon, B., Gullam, J., Leishman, D., Dawson, P., Devenish, C., Gaerty, K., Tomlinson, P. A., & Miller, H. (2023). Prenatal intravenous magnesium at 30-34 weeks' gestation and neurodevelopmental outcomes in offspring: The MAGENTA randomized clinical trial. JAMA, 330(7), 603-614. doi: 10.1001/jama.2023.12357
Journal - Research Article
Robinson, R., Girchenko, P., Pulakka, A., Heinonen, K., Lähdepuro, A., Lahti-Pulkkinen, M., … Darlow, B. A., … Horwood, L. J., … Räikkönen, K. (2023). ADHD symptoms and diagnosis in adult preterms: Systematic review, IPD meta-analysis, and register-linkage study. Pediatric Research, 93, 1399-1409. doi: 10.1038/s41390-021-01929-1
Journal - Research Article
Chevallier, M., Debillon, T., Darlow, B. A., Synnes, A. R., Pierrat, V., Hurrion, E., … Australian and New Zealand Neonatal Network (ANZNN), including Austin, N., Lynn, A., Edmonds, L., … Etude Epidémiologique sur les Petits Ages Gestationnels (EPIPAGE-2) Investigators. (2022). Mortality and significant neurosensory impairment in preterm infants: An international comparison. Archives of Disease in Childhood: Fetal & Neonatal Edition, 107, F317-F323. doi: 10.1136/archdischild-2021-322288
Journal - Research Article
Darlow, B. A., Harris, S. L., & Horwood, L. J. (2022). Little evidence for long-term harm from antenatal corticosteroids in a population-based very low birthweight young adult cohort. Paediatric & Perinatal Epidemiology, 36, 631-639. doi: 10.1111/ppe.12886
Journal - Research Article
Kim, H. M., Horwood, L. J., Harris, S. L., Bora, S., Darlow, B. A., & Woodward, L. J. (2022). Self-reported executive function problems in adults born very low birthweight. Paediatric & Perinatal Epidemiology, 36, 643-653. doi: 10.1111/ppe.12891
Journal - Research Article
McLeod, G. F. H., Horwood, L. J., Darlow, B. A., Boden, J. M., Martin, J., Spittlehouse, J. K., Carter, F. A., Jordan, J., Porter, R., Bell, C., Douglas, K., … McIntosh, V. V. W., … Vierck, E. (2022). Recruitment and retention of participants in longitudinal studies after a natural disaster. Longitudinal & Life Course Studies, 13(2), 287-306. doi: 10.1332/175795921X16168462584238
Journal - Research Article
Willis, J., Cunningham-Tisdall, C., Griffin, C., Scott, R., Darlow, B. A., Owens, N., Ferguson, J., Mackenzie, K., Williman, J., & de Bock, M. (2022). Type 1 diabetes diagnosed before age 15 years in Canterbury, New Zealand: A fifty year record of increasing incidence. Pediatric Diabetes, 23, 301-309. doi: 10.1111/pedi.13305
Journal - Research Article
Woodward, L. J., Horwood, L. J., Darlow, B. A., & Bora, S. (2022). Visuospatial working memory of children and adults born very preterm and/or very low birth weight. Pediatric Research, 91, 1436-1444. doi: 10.1038/s41390-021-01869-w
Journal - Research Article
Yang, J., Epton, M. J., Harris, S. L., Horwood, J., Kingsford, R. A., Troughton, R., Greer, C., & Darlow, B. A. (2022). Reduced exercise capacity in adults born at very low birth weight: A population-based cohort study. American Journal of Respiratory & Critical Care Medicine, 205, 88-98. doi: 10.1164/rccm.202103-0755OC
Journal - Research Article
Darlow, B. A., Horwood, J., Dhakal, B., Harris, S. L., McKelvey, V. A., Elliott, J. M., Yang, J., & Mackay, R. J. (2021). Biomarkers of ageing in New Zealand VLBW young adults and controls. Pediatric Research, 89, 533-539. doi: 10.1038/s41390-020-0882-x
Journal - Research Article
Doyle, L. W., & Darlow, B. A. (2021). The changing face of neonatal intensive care for infants born extremely preterm (<28 weeks’ gestation) [Review]. Seminars in Perinatology, 45, 151476. doi: 10.1016/j.semperi.2021.151476
Journal - Research Article
Eves, R., Mendonça, M., Baumann, N., Ni, Y., Darlow, B. A., Horwood, J., Woodward, L. J., … Wolke, D. (2021). Association of very preterm birth or very low birth weight with intelligence in adulthood: An individual participant data meta-analysis. JAMA Pediatrics, 175(8), e211058. doi: 10.1001/jamapediatrics.2021.1058
Journal - Research Article
Gagliardi, L., Rusconi, F., Reichman, B., Adams, M., Modi, N., Lehtonen, L., … Darlow, B. A., … the International Network for Evaluation of Outcomes (iNeo) of Neonates Investigators. (2021). Neonatal outcomes of extremely preterm twins by sex pairing: An international cohort study. Archives of Disease in Childhood: Fetal & Neonatal Edition, 106(1), F17-F24. doi: 10.1136/archdischild-2020-318832
Journal - Research Article
Greer, C., Harris, S. L., Troughton, R., Adamson, P. D., Horwood, J., Frampton, C., & Darlow, B. A. (2021). Right ventricular structure and function in young adults born preterm at very low birth weight. Journal of Clinical Medicine, 10(21), 4864. doi: 10.3390/jcm10214864
Journal - Research Article
Lui, K., Vento, M., Modi, N., Kusuda, S., Lehtonen, L., Håkansson, S., … on behalf of the International Network for Evaluating Outcomes of Neonates (iNeo) Investigators and Collaborators, including Darlow, B. A., Austin, N., & Lynn, A. (2021). Inter-center variability in neonatal outcomes of preterm infants: A longitudinal evaluation of 298 neonatal units in 11 countries. Seminars in Fetal & Neonatal Medicine, 26, 101196. doi: 10.1016/j.siny.2021.101196
Journal - Research Article
McKelvey, V., Darlow, B. A., Horwood, L. J., & Martin, J. (2021). Dental status of young adults born with very low birthweight: A national cohort study. Community Dentistry & Oral Epidemiology, 49, 240-248. doi: 10.1111/cdoe.12595
Journal - Research Article
Seaton, S. E., Draper, E. S., Adams, M., Kusuda, S., Håkansson, S., Helenius, K., … Darlow, B. A., … for the UK Neonatal Collaborative, on behalf of the International Network for Evaluating Outcomes of Neonates (iNeo) Investigators. (2021). Variations in neonatal length of stay of extremely preterm babies: An international comparison between iNeo networks. Journal of Pediatrics, 233, 26-32.e6. doi: 10.1016/j.jpeds.2021.02.015
Journal - Research Article
Darlow, B. A., Woodward, L. J., Levin, K. J., Melzer, T., & Horwood, L. J. (2020). Perinatal and childhood predictors of general cognitive outcome at 28 years in a very-low-birthweight national cohort. Developmental Medicine & Child Neurology, 62, 1423-1428. doi: 10.1111/dmcn.14649
Journal - Research Article
Harris, S. L., Bray, H., Troughton, R., Elliott, J., Frampton, C., Horwood, J., & Darlow, B. A. (2020). Cardiovascular outcomes in young adulthood in a population-based very low birth weight cohort. Journal of Pediatrics, 225, 74-79.e3. doi: 10.1016/j.jpeds.2020.06.023
Journal - Research Article
Helenius, K., Morisaki, N., Kusuda, S., Shah, P. S., Norman, M., Lehtonen, L., … Darlow, B. A., … on behalf of the International Network for Evaluation of Outcomes of neonates (iNeo), including Austin, N., Lynn, A., Edmonds, L., Broadbent, R., & Richardson, V. (2020). Survey shows marked variations in approaches to redirection of care for critically ill very preterm infants in 11 countries. Acta Paediatrica, 109, 1338-1345. doi: 10.1111/apa.15069
Journal - Research Article